Detailed information for compound 763729

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 370.485 | Formula: C22H30N2O3
  • H donors: 2 H acceptors: 2 LogP: 2.79 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCC1CN(CCN1Cc1ccc(cc1)OCC)Cc1ccccc1O
  • InChi: 1S/C22H30N2O3/c1-2-27-21-9-7-18(8-10-21)15-24-13-12-23(17-20(24)11-14-25)16-19-5-3-4-6-22(19)26/h3-10,20,25-26H,2,11-17H2,1H3
  • InChiKey: TYWFUCZKAMXABQ-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0015 0.0209 0.8796
Schistosoma mansoni glycyl-tRNA synthetase 0.0006 0.0008 0.0034
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0015 0.0209 1
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0209 0.2953
Schistosoma mansoni amine GPCR 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0016 0.0238 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0063 0.0279
Loa Loa (eye worm) melatonin receptor type 1A 0.0016 0.0238 0.1052
Schistosoma mansoni 60S ribosomal protein L21 0.0007 0.0025 0.0108
Leishmania major glucose transporter, lmgt1 0.0033 0.0614 0.8666
Onchocerca volvulus 0.0016 0.0238 1
Leishmania major protein kinase, putative 0.0033 0.0604 0.8534
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0209 0.0925
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0614 0.2715
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0006 0.0008 0.0132
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0209 0.0316
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.034 0.1507
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0016 0.0238 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis serotonin receptor 0.0016 0.0238 0.1052
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0006 0.0008 0.0192
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0238 0.1052
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0238 0.1052
Trypanosoma brucei glucose transporter 2A 0.0033 0.0614 0.8666
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0406 0.1797
Brugia malayi hypothetical protein 0.0015 0.0209 0.0925
Chlamydia trachomatis threonine--tRNA ligase 0.0006 0.0008 0.0192
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Brugia malayi Sugar transporter family protein 0.0015 0.0209 0.0925
Echinococcus multilocularis serotonin receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0238 0.1052
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0238 0.1052
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0006 0.0008 0.0239
Echinococcus multilocularis General substrate transporter 0.0091 0.1924 0.8515
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0238 0.1052
Plasmodium vivax CDK-related protein kinase 6, putative 0.045 1 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0016 0.0238 0.1052
Echinococcus granulosus neuropeptide receptor 0.0016 0.0238 0.1052
Plasmodium vivax hexose transporter 0.0106 0.2259 0.2259
Leishmania major hypothetical protein, conserved 0.0015 0.0209 0.2953
Onchocerca volvulus 0.0016 0.0238 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0006 0.0008 0.0034
Loa Loa (eye worm) sugar transporter 0.0106 0.2259 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0016 0.0238 0.1052
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0614 0.8666
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0015 0.0209 0.6415
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0278 0.3927
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0209 0.0925
Brugia malayi hypothetical protein 0.0015 0.0209 0.0925
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0016 0.0238 1
Onchocerca volvulus 0.0016 0.0238 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis solute carrier family 22 0.0015 0.0209 0.0925
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0238 0.1052
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0605 0.0605
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0006 0.0008 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0063 0.0279
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0238 0.1052
Echinococcus granulosus tachykinin peptides receptor 99D 0.0016 0.0238 0.1052
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0172 0.3729 0.3729
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0238 0.1052
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0151 0.0668
Brugia malayi Cam kinase protein 1 0.0033 0.0604 0.2674
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0063 0.0279
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0406 0.1797
Giardia lamblia Threonyl-tRNA synthetase 0.0006 0.0008 0.0132
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0016 0.0238 0.1052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Echinococcus granulosus cGMP dependent protein kinase 1 0.0008 0.0046 0.0202
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0768 0.3399
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0238 0.1052
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0015 0.0209 0.6415
Schistosoma mansoni biogenic amine receptor 0.0016 0.0238 0.1052
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Loa Loa (eye worm) hypothetical protein 0.0037 0.0705 0.3118
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0046 0.0202
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0406 0.0406
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0209 0.2953
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus G protein coupled receptor 139 0.0016 0.0238 0.1052
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0006 0.0008 0.0034
Schistosoma mansoni glucose transport protein 0.0106 0.2259 1
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0605 0.0605
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0016 0.0238 0.1052
Plasmodium falciparum mitogen-activated protein kinase 2 0.0172 0.3729 0.3729
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus peptide allatostatin:somatostatin 0.0016 0.0238 0.1052
Echinococcus multilocularis G protein coupled receptor 139 0.0016 0.0238 0.1052
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0008 0.0063 0.0279
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0209 0.0925
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) sugar transporter 0.0015 0.0209 0.0925
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0012 0.0151 0.0668
Brugia malayi follicle stimulating hormone receptor 0.0016 0.0238 0.1052
Entamoeba histolytica hypothetical protein 0.0024 0.0406 0.6679
Schistosoma mansoni neuropeptide receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis neuropeptide s receptor 0.0016 0.0238 0.1052
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0016 0.0238 0.1052
Brugia malayi G-protein coupled receptor 0.0016 0.0238 0.1052
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0006 0.0008 0.0192
Brugia malayi AKH receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Schistosoma mansoni voltage-gated potassium channel 0.0007 0.0025 0.0108
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0209 0.0925
Brugia malayi Melatonin receptor type 1A 0.0016 0.0238 0.1052
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0614 0.8666
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Toxoplasma gondii sugar transporter ST3 0.0015 0.0209 0.0316
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0063 0.0279
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Schistosoma mansoni neuropeptide receptor 0.0016 0.0238 0.1052
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0209 0.0209
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0063 0.0279
Echinococcus granulosus neuropeptide s receptor 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0015 0.0209 0.8796
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0406 0.5736
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0406 0.5736
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0406 0.1797
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0614 0.8666
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0589 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0326 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Schistosoma mansoni sugar transporter 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0006 0.0008 0.0034
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0604 0.2674
Loa Loa (eye worm) AGC/PKG protein kinase 0.0008 0.0046 0.0202
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0016 0.0238 0.1052
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Entamoeba histolytica protein kinase, putative 0.0033 0.0604 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Echinococcus multilocularis neuropeptide receptor A26 0.0016 0.0238 0.1052
Brugia malayi G protein-coupled receptor F59B2.13 0.0016 0.0238 0.1052
Brugia malayi major facilitator superfamily protein 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0015 0.0209 0.8796
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0238 0.1052
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0614 0.8666
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0209 0.0925
Onchocerca volvulus Neuropeptide F receptor homolog 0.0016 0.0238 1
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0008 0.0063 0.0279
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0063 0.0279
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0063 0.0279
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0238 0.1052
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0209 0.5147
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0605 0.0914
Brugia malayi ORL1-like opioid receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0008 0.011
Plasmodium vivax glycine--tRNA ligase, putative 0.0006 0.0008 0.0008
Onchocerca volvulus 0.0015 0.0209 0.8796
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0015 0.0209 0.8796
Giardia lamblia Hexose transporter 0.0015 0.0209 0.3547
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0238 0.1052
Schistosoma mansoni opsin-like receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis somatostatin receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0063 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0016 0.0238 1
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0026 0.0455 0.2014
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0008 0.0046 0.0202
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0008 0.0063 0.0279
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0238 0.1052
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0605 0.0914
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0016 0.0238 0.1052
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0406 0.0614
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0008 0.0063 0.0279
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0708 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0604 0.2674
Loa Loa (eye worm) hypothetical protein 0.0032 0.0589 0.2608
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0016 0.0238 0.1052
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0238 0.1052
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0006 0.0008 0.0012
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0008 0.011
Schistosoma mansoni sugar transporter 0.0015 0.0209 0.0925
Schistosoma mansoni amine GPCR 0.0016 0.0238 0.1052
Echinococcus multilocularis orexin receptor type 2 0.0016 0.0238 0.1052
Schistosoma mansoni growth hormone secretagogue receptor 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0015 0.0209 0.8796
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0209 0.0925
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0406 0.6891
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus hypothetical protein 0.0016 0.0238 0.1052
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0209 0.2953
Plasmodium vivax threonine--tRNA ligase, putative 0.0006 0.0008 0.0008
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0238 0.1052
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0605 0.0605
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0126 0.3112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0016 0.0238 0.1052
Schistosoma mansoni hypothetical protein 0.0106 0.2259 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2259 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0406 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0063 0.0279
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0589 0.2608
Schistosoma mansoni hypothetical protein 0.0016 0.0238 0.1052
Brugia malayi G protein-coupled receptor 0.0016 0.0238 0.1052
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0016 0.0238 1
Brugia malayi Serotonin receptor 0.0016 0.0238 0.1052
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0238 0.1052
Echinococcus granulosus neuropeptide receptor A26 0.0016 0.0238 0.1052
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0209 0.0925
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0006 0.0008 0.011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Schistosoma mansoni hypothetical protein 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0015 0.0209 0.8796
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0605 0.0605
Loa Loa (eye worm) hypothetical protein 0.0012 0.0151 0.0668
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0589 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0605 0.0605
Entamoeba histolytica protein kinase, putative 0.0033 0.0604 1
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Brugia malayi RE15519p 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2259 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2259 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0708 1
Schistosoma mansoni protein kinase 0.0033 0.0604 0.2674
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0015 0.0209 0.8796
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Toxoplasma gondii facilitative glucose transporter GT1 0.0106 0.2259 0.3416
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0046 0.0202
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0016 0.0238 0.1052
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0209 0.0925
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0238 0.1052
Echinococcus granulosus solute carrier family 22 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.004 0.0768 0.3399
Echinococcus granulosus dro:myosuppressin receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Plasmodium falciparum cGMP-dependent protein kinase 0.0008 0.0046 0.0046
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0326 0.5529
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0106 0.2259 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0016 0.0238 0.1052
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0167 0.0741
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0604 0.2674
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0605 0.0605
Schistosoma mansoni biogenic amine receptor 0.0016 0.0238 0.1052
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0126 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus 7TM GPCR rhodopsin 0.0016 0.0238 0.1052
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2259 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0604 0.2674
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0238 0.1052
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0063 0.0279
Schistosoma mansoni sugar transporter 0.0015 0.0209 0.0925
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0008 0.0046 0.0069
Echinococcus granulosus alpha 1A adrenergic receptor 0.0016 0.0238 0.1052
Schistosoma mansoni hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0559 0.2474
Onchocerca volvulus 0.0016 0.0238 1
Brugia malayi glycyl-tRNA synthetase 0.0006 0.0008 0.0034
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0406 1
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0919 0.4067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0238 0.1052
Leishmania major threonyl-tRNA synthetase, putative 0.0006 0.0008 0.011
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0919 0.4067
Loa Loa (eye worm) TYRA-2 protein 0.0016 0.0238 0.1052
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Onchocerca volvulus 0.0015 0.0209 0.8796
Plasmodium vivax sugar transporter, putative 0.0015 0.0209 0.0209
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0063 0.0279
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0604 0.2674
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0589 0.2608
Plasmodium falciparum threonine--tRNA ligase 0.0006 0.0008 0.0008
Echinococcus granulosus solute carrier family 22 0.0015 0.0209 0.0925
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0012 0.0151 0.0668
Echinococcus multilocularis sex peptide receptor 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0015 0.0209 0.8796
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0015 0.0209 0.8796
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0406 0.0406
Onchocerca volvulus 0.0015 0.0209 0.8796
Loa Loa (eye worm) hypothetical protein 0.0032 0.0589 0.2608
Leishmania major glucose transporter, lmgt3 0.0033 0.0614 0.8666
Brugia malayi larval opioid receptor 0.0016 0.0238 0.1052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Echinococcus granulosus fmrfamide receptor 0.0016 0.0238 0.1052
Echinococcus granulosus orexin receptor type 2 0.0016 0.0238 0.1052
Echinococcus multilocularis solute carrier family 22 0.0015 0.0209 0.0925
Schistosoma mansoni opsin-like receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0016 0.0238 0.1052
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0589 0.2608
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0012 0.0151 0.0668
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0016 0.0238 0.1052
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0604 0.2674
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0614 0.2715
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0063 0.0279
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0589 0.2608
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus sex peptide receptor 0.0016 0.0238 0.1052
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0046 0.0202
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis G-protein coupled receptor, putative 0.0016 0.0238 0.1052
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2259 1
Echinococcus granulosus serotonin receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0604 0.2674
Echinococcus granulosus g protein coupled receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0016 0.0238 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0831 0.3678
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Trypanosoma brucei sugar transporter, putative 0.0015 0.0209 0.2953
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0016 0.0238 0.1052
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0209 0.5147
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0063 0.0279
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus 7tm_1 domain containing protein 0.0016 0.0238 0.1052
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0604 0.8534
Treponema pallidum threonyl-tRNA synthetase 0.0006 0.0008 0.0616
Leishmania major glucose transporter, lmgt2 0.0033 0.0614 0.8666
Echinococcus granulosus g-protein coupled receptor 0.0016 0.0238 0.1052
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0172 0.3729 0.5637
Echinococcus multilocularis neuropeptide FF receptor 2 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Schistosoma mansoni neuropeptide f receptor 76f 0.0016 0.0238 0.1052
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0209 0.0925
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus Threonyl tRNA synthetase C 0.0006 0.0008 0.0034
Schistosoma mansoni alpha-1 adrenergic receptor 0.0016 0.0238 0.1052
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Brugia malayi GnHR receptor homolog 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0016 0.0238 1
Schistosoma mansoni glucose transport protein 0.0106 0.2259 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Brugia malayi Dopamine receptor protein 1 0.0016 0.0238 0.1052
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0708 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0614 0.8666
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0008 0.0046 0.0202
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0006 0.0008 0.0034
Brugia malayi G-protein coupled receptor 0.0016 0.0238 0.1052
Giardia lamblia Glycyl-tRNA synthetase 0.0006 0.0008 0.0132
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0614 0.8666
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Echinococcus multilocularis voltage gated potassium channel 0.0012 0.0151 0.0668
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0016 0.0238 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0708 0.0708
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0406 0.1797
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Schistosoma mansoni histamine h1 receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0024 0.0406 0.1797
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0238 0.1052
Schistosoma mansoni opsin-like receptor 0.0016 0.0238 0.1052
Echinococcus granulosus General substrate transporter 0.0091 0.1924 0.8515
Brugia malayi Egg laying defective protein 4 0.0008 0.0046 0.0202
Echinococcus granulosus allatostatin A receptor 0.0016 0.0238 0.1052
Schistosoma mansoni adenoreceptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Leishmania major protein kinase, putative 0.0008 0.0046 0.0644
Echinococcus granulosus neuropeptide receptor 0.0016 0.0238 0.1052
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0831 0.3678
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Echinococcus multilocularis dro:myosuppressin receptor 0.0016 0.0238 0.1052
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0106 0.2259 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0016 0.0238 1
Schistosoma mansoni neuropeptide receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0209 0.0925
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0209 0.2953
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0406 0.1797
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0008 0.0063 0.0279
Echinococcus granulosus g protein coupled receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis allatostatin A receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Leishmania major protein kinase, putative 0.0008 0.0046 0.0644
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus voltage gated potassium channel 0.0012 0.0151 0.0668
Schistosoma mansoni amine GPCR 0.0016 0.0238 0.1052
Schistosoma mansoni myosin xvIII 0.0016 0.0238 0.1052
Plasmodium falciparum protein kinase 7 0.03 0.6615 0.6615
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0063 0.0279
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0708 1
Brugia malayi major facilitator superfamily protein 0.0015 0.0209 0.0925
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0015 0.0209 0.8796
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0006 0.0008 0.011
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0151 0.0668
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0015 0.0209 0.8796
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Brugia malayi Dopamine receptor protein 2 0.0016 0.0238 0.1052
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0006 0.0007 0.0101
Onchocerca volvulus 0.0016 0.0238 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0016 0.0238 0.1052
Echinococcus granulosus solute carrier family 22 0.0015 0.0209 0.0925
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0209 0.5147
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0589 0.9752
Toxoplasma gondii sugar transporter ST2 0.0015 0.0209 0.0316
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0604 0.2674
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0106 0.2259 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus cGMP dependent protein kinase 0.0008 0.0046 0.0202
Schistosoma mansoni neuropeptide receptor 0.0016 0.0238 0.1052
Brugia malayi hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0605 0.0605
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0238 0.1052
Onchocerca volvulus 0.0016 0.0238 1
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0209 0.0925
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0006 0.0008 0.0034
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0238 0.1052
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0605 0.0605
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0406 0.1797
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Brugia malayi Sugar transporter family protein 0.0015 0.0209 0.0925
Brugia malayi putative neuropeptide receptor 0.0016 0.0238 0.1052
Schistosoma mansoni amine GPCR 0.0016 0.0238 0.1052
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0406 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0708 1
Toxoplasma gondii glycyl-tRNA synthetase 0.0006 0.0008 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0708 0.107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0589 0.2608
Schistosoma mansoni protein kinase 0.0033 0.0604 0.2674
Mycobacterium ulcerans sugar transporter 0.0015 0.0209 0.5147
Trypanosoma cruzi hexose transporter 0.0033 0.0614 0.8666
Onchocerca volvulus 0.0016 0.0238 1
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0238 0.1052
Brugia malayi Dopamine receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus somatostatin receptor 0.0016 0.0238 0.1052
Plasmodium falciparum hexose transporter 0.0106 0.2259 0.2259
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0238 0.1052
Schistosoma mansoni protein kinase 0.0033 0.0604 0.2674
Brugia malayi hypothetical protein 0.0015 0.0209 0.0925
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0604 0.2674
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0016 0.0238 0.1052
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0238 0.1052
Echinococcus granulosus solute carrier family 22 0.0015 0.0209 0.0925
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Schistosoma mansoni sugar transporter 0.0015 0.0209 0.0925
Loa Loa (eye worm) hypothetical protein 0.0015 0.0209 0.0925
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0063 0.0279
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0604 0.2674
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Schistosoma mansoni biogenic amine receptor 0.0016 0.0238 0.1052
Echinococcus granulosus g protein coupled receptor 0.0016 0.0238 0.1052
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0209 0.0925
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0604 0.2674
Schistosoma mansoni glucose transport protein 0.0106 0.2259 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus cGMP dependent protein kinase 1 0.0008 0.0046 0.0202
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0006 0.0008 0.0034
Brugia malayi neuropeptide F receptor 0.0016 0.0238 0.1052
Brugia malayi neuropeptide F receptor 0.0016 0.0238 0.1052
Schistosoma mansoni hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0559 0.2474
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0614 0.2715
Brugia malayi Serotonin receptor 0.0016 0.0238 0.1052
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0209 0.2953
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0831 0.3678
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0016 0.0238 0.1052
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0326 1
Echinococcus multilocularis solute carrier family 22 0.0015 0.0209 0.0925
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.2259 1
Trypanosoma brucei glucose transporter 1E 0.0033 0.0614 0.8666
Schistosoma mansoni amine GPCR 0.0016 0.0238 0.1052
Brugia malayi putative neuropeptide receptor NPR1 0.0016 0.0238 0.1052
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0614 0.8666
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0063 0.0279
Brugia malayi sulfakinin receptor protein 0.0016 0.0238 0.1052
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0604 0.2674
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0614 0.2715
Echinococcus multilocularis expressed conserved protein 0.0008 0.0046 0.0202
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0831 0.3678
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0605 0.0914
Echinococcus granulosus glycyl tRNA synthetase 0.0006 0.0008 0.0034
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0589 0.2608
Echinococcus multilocularis solute carrier family 22 0.0015 0.0209 0.0925
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0238 0.1052
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0209 0.0925
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0016 0.0238 0.1052
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Echinococcus multilocularis g-protein coupled receptor 0.0016 0.0238 0.1052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Brugia malayi Tachykinin-like peptides receptor 99D 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0604 0.2674
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0614 0.2715
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0614 0.2715
Toxoplasma gondii protein kinase, putative 0.03 0.6615 1
Brugia malayi Sugar transporter family protein 0.0106 0.2259 1
Echinococcus multilocularis glycyl tRNA synthetase 0.0006 0.0008 0.0034
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0589 0.2608
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0605 0.0605
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0238 0.1052
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0126 0.3112
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0406 0.5736
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0209 0.0925
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0015 0.0209 0.8796
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0063 0.0279
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0614 0.2715
Onchocerca volvulus 0.0016 0.0238 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0016 0.0238 0.1052
Giardia lamblia Sugar-proton symporter 0.0015 0.0209 0.3547
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0406 0.6891
Onchocerca volvulus 0.0015 0.0209 0.8796
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0604 0.2674
Brugia malayi Cyclic-nucleotide gated cation channel 0.0008 0.0063 0.0279
Onchocerca volvulus Putative transporter 0.0015 0.0209 0.8796
Toxoplasma gondii sugar transporter ST1 0.0015 0.0209 0.0316
Schistosoma mansoni glucose transporter 0.0015 0.0209 0.0925
Onchocerca volvulus 0.0016 0.0238 1
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0209 0.0925
Trypanosoma brucei glucose transporter, putative 0.0033 0.0614 0.8666
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0238 0.1052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0238 0.1052

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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