Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Tolloid protein 1 | 0.0139 | 0.1667 | 0.1667 |
Echinococcus multilocularis | Mastin | 0.002 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0105 | 0.1201 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0094 | 0.1058 | 0.8342 |
Echinococcus granulosus | lamin | 0.0029 | 0.018 | 0.018 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0048 | 0.0435 | 0.3512 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.0718 | 0.2665 |
Toxoplasma gondii | rhoptry neck protein RON9 | 0.0076 | 0.0809 | 0.5565 |
Onchocerca volvulus | 0.0053 | 0.0501 | 0.3799 | |
Echinococcus multilocularis | enteropeptidase | 0.002 | 0.0049 | 0.0049 |
Echinococcus multilocularis | cubilin | 0.0032 | 0.0207 | 0.0207 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0049 | 0.0181 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.002 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | CUB domain-containing protein | 0.0032 | 0.0207 | 0.0768 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0048 | 0.0435 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.018 | 0.0667 |
Loa Loa (eye worm) | lectin C-type domain-containing protein | 0.0032 | 0.0207 | 0.0768 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0138 | 0.1645 | 0.1645 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0313 | 0.0313 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.002 | 0.0049 | 0.0049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0134 | 0.3078 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0049 | 0.0049 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0048 | 0.0435 | 0.0435 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0032 | 0.0207 | 0.167 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0809 | 0.6522 |
Echinococcus multilocularis | lamin | 0.0029 | 0.018 | 0.018 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0048 | 0.0435 | 0.0435 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0301 | 0.6922 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Brugia malayi | zinc metalloproteinase toh-2 precursor | 0.0032 | 0.0207 | 0.167 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.002 | 0.0049 | 0.0049 |
Echinococcus granulosus | c4b binding protein beta chain | 0.0076 | 0.0809 | 0.0809 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.0718 | 0.2665 |
Onchocerca volvulus | 0.0029 | 0.018 | 0.1098 | |
Echinococcus multilocularis | fibrillin 1 | 0.0108 | 0.124 | 0.124 |
Trypanosoma brucei | serine peptidase, clan SB, family S8-like protein | 0.0032 | 0.0207 | 0.4755 |
Brugia malayi | RNA binding protein | 0.0069 | 0.0718 | 0.5793 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0139 | 0.1667 | 0.1667 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.018 | 0.018 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0051 | 0.0476 | 0.0476 |
Onchocerca volvulus | Arrow homolog | 0.0108 | 0.124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Schistosoma mansoni | thyroid hormone receptor | 0.0149 | 0.1794 | 0.1794 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0048 | 0.0435 | 1 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0809 | 0.6522 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.018 | 0.018 |
Echinococcus multilocularis | laminin | 0.0108 | 0.124 | 0.124 |
Echinococcus granulosus | neuropilin nrp and tolloid tll | 0.0032 | 0.0207 | 0.0207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0134 | 0.3066 |
Mycobacterium ulcerans | hypothetical protein | 0.002 | 0.0049 | 0.5 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.002 | 0.0049 | 0.0049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0268 | 0.6145 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Echinococcus granulosus | C type lectin domian containing protein | 0.0076 | 0.0809 | 0.0809 |
Onchocerca volvulus | 0.0032 | 0.0207 | 0.1328 | |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.0718 | 0.0718 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0809 | 0.6522 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Echinococcus multilocularis | neuropilin (nrp) and tolloid (tll) | 0.0032 | 0.0207 | 0.0207 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0048 | 0.0435 | 0.0435 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0301 | 0.6922 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0149 | 0.1794 | 0.1794 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0134 | 0.3078 |
Brugia malayi | CUB domain containing protein | 0.0032 | 0.0207 | 0.167 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0139 | 0.1667 | 0.1667 |
Schistosoma mansoni | neuropilin (nrp) and tolloid (tll)-like | 0.0032 | 0.0207 | 0.0207 |
Brugia malayi | Zinc metalloproteinase toh-2 precursor | 0.0032 | 0.0207 | 0.167 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0049 | 0.0181 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0268 | 0.6145 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.124 | 0.4601 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0134 | 0.3066 |
Toxoplasma gondii | thioredoxin reductase | 0.0041 | 0.034 | 0.075 |
Schistosoma mansoni | thyroid hormone receptor | 0.0149 | 0.1794 | 0.1794 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0134 | 0.3078 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0313 | 0.2525 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Echinococcus multilocularis | C type lectin domian containing protein | 0.0076 | 0.0809 | 0.0809 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0048 | 0.0435 | 1 |
Brugia malayi | pregnancy-associated plasma protein-A | 0.0076 | 0.0809 | 0.6522 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0105 | 0.1201 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.1645 | 0.1645 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.018 | 0.1449 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0207 | 0.167 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0313 | 0.0313 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0041 | 0.034 | 0.7818 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Brugia malayi | Trypsin family protein | 0.002 | 0.0049 | 0.0394 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0048 | 0.0435 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0094 | 0.1058 | 0.8342 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.002 | 0.0052 | 0.1204 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0172 | 0.3945 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.018 | 0.018 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0053 | 0.0501 | 0.0501 |
Onchocerca volvulus | 0.0032 | 0.0207 | 0.1328 | |
Echinococcus multilocularis | CUB | 0.0032 | 0.0207 | 0.0207 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0048 | 0.0435 | 1 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Toxoplasma gondii | rhoptry neck protein RON1 | 0.0076 | 0.0809 | 0.5565 |
Echinococcus granulosus | Mastin | 0.002 | 0.0049 | 0.0049 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Schistosoma mansoni | lamin | 0.0029 | 0.018 | 0.018 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0048 | 0.0435 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0718 | 0.0718 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0207 | 0.4755 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0094 | 0.1058 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Loa Loa (eye worm) | trypsin family protein | 0.002 | 0.0049 | 0.0181 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0094 | 0.1058 | 0.8342 |
Echinococcus granulosus | CUB | 0.0032 | 0.0207 | 0.0207 |
Plasmodium falciparum | apical sushi protein | 0.0076 | 0.0809 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0168 | 0.3855 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.002 | 0.0049 | 0.0049 |
Brugia malayi | Trypsin family protein | 0.002 | 0.0049 | 0.0394 |
Schistosoma mansoni | egf-like domain protein | 0.0108 | 0.124 | 0.124 |
Brugia malayi | CUB domain containing protein | 0.0032 | 0.0207 | 0.167 |
Brugia malayi | glutathione reductase | 0.0041 | 0.034 | 0.2746 |
Brugia malayi | Thioredoxin reductase | 0.0041 | 0.034 | 0.2746 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.018 | 0.1449 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0048 | 0.0435 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0076 | 0.0809 | 0.6522 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0172 | 0.3945 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0718 | 0.0718 |
Echinococcus multilocularis | c4b binding protein beta chain | 0.0076 | 0.0809 | 0.0809 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.018 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.124 | 0.4601 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0313 | 0.0313 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0108 | 0.124 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0268 | 0.6145 |
Brugia malayi | Lectin C-type domain containing protein | 0.0032 | 0.0207 | 0.167 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0207 | 0.0207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0268 | 0.6145 |
Echinococcus granulosus | enteropeptidase | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Onchocerca volvulus | 0.0032 | 0.0207 | 0.1328 | |
Brugia malayi | Suppressor of lurcher protein 1 precursor | 0.0032 | 0.0207 | 0.167 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0268 | 0.6145 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0313 | 0.0313 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.0032 | 0.0207 | 0.0768 |
Loa Loa (eye worm) | CUB domain-containing protein | 0.0032 | 0.0207 | 0.0768 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0755 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.018 | 0.0667 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0809 | 0.6522 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.0718 | 0.0718 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0755 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0268 | 0.6145 |
Brugia malayi | Nematode astacin protease protein 30 | 0.0032 | 0.0207 | 0.167 |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Schistosoma mansoni | lamin | 0.0029 | 0.018 | 0.018 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.0718 | 0.2665 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0048 | 0.0435 | 1 |
Plasmodium vivax | apical sushi protein, putative | 0.0076 | 0.0809 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.1667 | 0.6184 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0718 | 0.0718 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0039 | 0.0302 | 0.6934 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Brugia malayi | Fibulin-1 precursor | 0.0108 | 0.124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0049 | 0.0181 |
Brugia malayi | CUB domain containing protein | 0.0032 | 0.0207 | 0.167 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0168 | 0.3855 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0108 | 0.124 | 0.4601 |
Brugia malayi | CUB domain containing protein | 0.0032 | 0.0207 | 0.167 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0042 | 0.0348 | 0.0348 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0039 | 0.0302 | 0.6934 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0134 | 0.3078 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0301 | 0.6922 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0139 | 0.1667 | 0.6184 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0041 | 0.034 | 0.78 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.0032 | 0.0207 | 0.4755 |
Brugia malayi | CUB domain containing protein | 0.0032 | 0.0207 | 0.167 |
Echinococcus multilocularis | cubilin | 0.0032 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0049 | 0.0181 |
Echinococcus granulosus | cubilin | 0.0032 | 0.0207 | 0.0207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.022 | 0.5047 |
Onchocerca volvulus | Putative cubilin | 0.0032 | 0.0207 | 0.1328 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | neuropilin (nrp) and tolloid (tll)-like | 0.0032 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0049 | 0.0181 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0206 | 0.4722 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0301 | 0.6922 |
Brugia malayi | Sushi domain | 0.0076 | 0.0809 | 0.6522 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0048 | 0.0435 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0048 | 0.0435 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Brugia malayi | Trypsin family protein | 0.002 | 0.0049 | 0.0394 |
Schistosoma mansoni | c4b-binding protein beta chain | 0.0076 | 0.0809 | 0.0809 |
Brugia malayi | hypothetical protein | 0.002 | 0.0049 | 0.0394 |
Echinococcus granulosus | tumor protein p63 | 0.0364 | 0.4707 | 0.4707 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0048 | 0.0435 | 0.1616 |
Loa Loa (eye worm) | zinc metalloproteinase toh-2 | 0.0032 | 0.0207 | 0.0768 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0105 | 0.1201 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0108 | 0.124 | 1 |
Loa Loa (eye worm) | pregnancy-associated plasma protein-E | 0.0076 | 0.0809 | 0.3001 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.0718 | 0.5793 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0049 | 0.0181 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0023 | 0.009 | 0.207 |
Brugia malayi | Kelch motif family protein | 0.0032 | 0.0207 | 0.167 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0809 | 0.6522 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0172 | 0.0639 |
Loa Loa (eye worm) | glutathione reductase | 0.0041 | 0.034 | 0.1263 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0809 | 0.6522 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0108 | 0.124 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0207 | 0.0207 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0207 | 0.0207 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0207 | 0.0207 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.002 | 0.0049 | 0.0049 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.0032 | 0.0207 | 0.4755 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0051 | 0.0476 | 0.0476 |
Onchocerca volvulus | 0.0029 | 0.018 | 0.1098 | |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0039 | 0.0302 | 0.6934 |
Trypanosoma brucei | trypanothione reductase | 0.0041 | 0.034 | 0.7818 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0108 | 0.124 | 1 |
Echinococcus multilocularis | musashi | 0.0029 | 0.018 | 0.018 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0105 | 0.1201 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.002 | 0.0049 | 0.0049 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0718 | 0.0718 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0048 | 0.0435 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0094 | 0.1058 | 0.8342 |
Brugia malayi | Trypsin family protein | 0.002 | 0.0049 | 0.0394 |
Loa Loa (eye worm) | DPY-31 protein | 0.0032 | 0.0207 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Onchocerca volvulus | 0.0032 | 0.0207 | 0.1328 | |
Onchocerca volvulus | 0.0076 | 0.0809 | 0.6379 | |
Brugia malayi | Nematode astacin protease protein 30 | 0.0032 | 0.0207 | 0.167 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0207 | 0.0207 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.0718 | 0.5793 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.002 | 0.0049 | 0.0394 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0809 | 0.6522 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0041 | 0.034 | 0.1263 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.0718 | 0.0718 |
Brugia malayi | astacin protease protein 30 | 0.0032 | 0.0207 | 0.167 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.2695 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0301 | 0.6922 |
Echinococcus multilocularis | tumor protein p63 | 0.0364 | 0.4707 | 0.4707 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0049 | 0.0181 |
Echinococcus granulosus | laminin | 0.0108 | 0.124 | 0.124 |
Giardia lamblia | GTOR | 0.0048 | 0.0435 | 0.5 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0108 | 0.124 | 0.4601 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.002 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0501 | 0.186 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0809 | 0.3001 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0094 | 0.1058 | 0.8342 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0042 | 0.0348 | 0.0348 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0207 | 0.0768 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0172 | 0.3945 |
Leishmania major | trypanothione reductase | 0.0041 | 0.034 | 0.7818 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0138 | 0.1645 | 0.1645 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.124 | 0.4601 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.018 | 0.018 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0134 | 0.3066 |
Brugia malayi | Trypsin-like protease protein 5 | 0.002 | 0.0049 | 0.0394 |
Echinococcus granulosus | cubilin | 0.0032 | 0.0207 | 0.0207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0268 | 0.6145 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0 % | Inhibition of human alphaVbeta3 receptor expressed in african green monkey Vero E6 cells assessed as inhibition of SNV infection in cells at 1 uM by immunofluorescent assay | ChEMBL. | 20951038 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.