Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0051 | 0.0726 | 0.071 |
Loa Loa (eye worm) | MBCTL1 | 0.0058 | 0.0948 | 0.1247 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.075 | 0.0735 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0055 | 0.0867 | 0.5 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0058 | 0.0948 | 0.0933 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0055 | 0.0867 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.075 | 0.0735 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0051 | 0.0726 | 0.071 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.075 | 0.0987 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.075 | 0.0968 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.0867 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0016 | 0.0022 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0016 | 0.0022 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.075 | 0.0735 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0058 | 0.0948 | 0.0933 |
Onchocerca volvulus | 0.0051 | 0.0726 | 0.2046 | |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3483 | 0.4585 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0051 | 0.0726 | 0.071 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0058 | 0.0948 | 0.0933 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.075 | 0.0735 |
Brugia malayi | NNMT/PNMT/TEMT family protein | 0.0269 | 0.7597 | 1 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0051 | 0.0726 | 0.071 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.075 | 0.0735 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0055 | 0.0867 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0016 | 0.0022 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0058 | 0.0948 | 0.0933 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0201 | 0.5442 | 0.5435 |
Onchocerca volvulus | Huntingtin homolog | 0.0139 | 0.3483 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0139 | 0.3483 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0051 | 0.0726 | 0.0955 |
Schistosoma mansoni | hypothetical protein | 0.031 | 0.8872 | 0.887 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.7597 | 1 |
Echinococcus multilocularis | geminin | 0.0345 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.7597 | 1 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0051 | 0.0726 | 0.071 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.075 | 0.0735 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0051 | 0.0726 | 0.071 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0051 | 0.0726 | 0.071 |
Brugia malayi | hypothetical protein | 0.0139 | 0.3483 | 0.4573 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0055 | 0.0867 | 0.5 |
Brugia malayi | mbt repeat family protein | 0.0051 | 0.0726 | 0.0936 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0867 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3483 | 0.4585 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.0269 | 0.7597 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0055 | 0.0867 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0726 | 0.0955 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0058 | 0.0948 | 0.0933 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0055 | 0.0867 | 0.5 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0248 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0948 | 0.1247 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0051 | 0.0726 | 0.2046 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0201 | 0.5442 | 0.5435 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0867 | 0.1122 |
Brugia malayi | mbt repeat family protein | 0.0051 | 0.0726 | 0.0936 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0055 | 0.0867 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.075 | 0.0735 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0058 | 0.0948 | 0.1228 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.