Detailed information for compound 784150

Basic information

Technical information
  • TDR Targets ID: 784150
  • Name: N-(2,6-Dimethylphenyl)-4-nitrobenzenesulfonam ide
  • MW: 306.337 | Formula: C14H14N2O4S
  • H donors: 1 H acceptors: 4 LogP: 3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1NS(=O)(=O)c1ccc(cc1)[N+](=O)[O-])C
  • InChi: 1S/C14H14N2O4S/c1-10-4-3-5-11(2)14(10)15-21(19,20)13-8-6-12(7-9-13)16(17)18/h3-9,15H,1-2H3
  • InChiKey: YJQBCUWRWHQCEJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,6-dimethylphenyl)-4-nitro-benzenesulfonamide
  • 4-Nitro-N-(2,6-xylyl)benzenesulfonamide
  • A0653/0030366
  • ZINC00059852

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.048 0.1381
Brugia malayi SET domain containing protein 0.0013 0.0038 0.0054
Giardia lamblia Kinase, PLK 0.0099 0.1264 0.178
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.001 0.001
Brugia malayi jmjC domain containing protein 0.01 0.1279 0.1802
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.1279 0.1279
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0436 0.1247
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.1264 0.1754
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0986 0.0986
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0893 0.1258
Brugia malayi jmjC domain containing protein 0.0037 0.0379 0.0534
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0098 0.1246 0.1246
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0022 0.0031
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0022 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0291 0.0291
Giardia lamblia PHD finger protein 15 0.003 0.0288 0.0405
Brugia malayi Heterochromatin protein 1 0.0073 0.0893 0.1258
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0436 0.0584
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0022 0.0022
Brugia malayi glucose-6-phosphate dehydrogenase 0.0098 0.1246 0.1755
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.2912 0.4103
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0201 0.0222
Echinococcus multilocularis Chromo domain 0.0012 0.0022 0.0022
Brugia malayi PHD-finger family protein 0.003 0.0288 0.0405
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0288 0.0288
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0201 0.0283
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0031 0.0291 0.041
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.1279 0.1279
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0044 0.003
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0098 0.1246 0.1704
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0379 0.0379
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0106 0.137 0.1904
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.0507 0.7099 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.1264 0.3747
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0201 0.0304
Loa Loa (eye worm) hypothetical protein 0.0024 0.0201 0.0283
Onchocerca volvulus 0.0043 0.0461 0.1325
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0022 0.0031
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0201 0.0304
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0218 0.0411
Schistosoma mansoni hypothetical protein 0.0012 0.0022 0.0022
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0218 0.0364
Loa Loa (eye worm) hypothetical protein 0.003 0.0288 0.0405
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0031
Schistosoma mansoni hypothetical protein 0.003 0.0288 0.0288
Echinococcus multilocularis microtubule associated protein 2 0.071 1 1
Echinococcus granulosus chromobox protein 1 0.0073 0.0893 0.0893
Schistosoma mansoni microtubule-associated protein tau 0.071 1 1
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0064 0.0762 0.2238
Brugia malayi Protein cec-1. 0.0012 0.0022 0.0031
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0201 0.0351
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0201 0.0252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0022 0.0031
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0221 0.3016 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.1264 0.1729
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0893 0.1231
Plasmodium falciparum protein-S-isoprenylcysteine O-methyltransferase, putative 0.0507 0.7099 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0112 0.0127
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0218 0.0247
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0218 0.0277
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.0405
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0022 0.0022
Schistosoma mansoni chromobox protein 0.0073 0.0893 0.0893
Onchocerca volvulus Alhambra homolog 0.003 0.0288 0.0801
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0034 0.0335 0.0813
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Loa Loa (eye worm) hypothetical protein 0.0032 0.0309 0.0436
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0201 0.0222
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0098 0.1246 0.1246
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0022 0.0031
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0022 0.0022
Echinococcus granulosus chromobox protein 1 0.0073 0.0893 0.0893
Trichomonas vaginalis set domain proteins, putative 0.0244 0.3335 0.4682
Trichomonas vaginalis chromobox protein, putative 0.0044 0.048 0.0647
Schistosoma mansoni protein-s-isoprenylcysteine o-methyltransferase 0.0507 0.7099 0.7099
Loa Loa (eye worm) hypothetical protein 0.0024 0.0201 0.0283
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.1264 0.1754
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0201 0.0304
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0379 0.0379
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0022 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.1264 0.1754
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0201 0.0304
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0461 0.0461
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.1264 0.1729
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0064 0.0762 0.1074
Giardia lamblia Isoprenylcysteine carboxyl methyltransferase 0.0507 0.7099 1
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0106 0.137 0.1904
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0106 0.137 0.1904
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0022 0.0031
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0098 0.1246 0.3903
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0288 0.0405
Mycobacterium ulcerans hypothetical protein 0.0026 0.0218 0.0364
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.0507 0.7099 1
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0211 0.0211
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0022 0.0022
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0291 0.0291
Entamoeba histolytica hypothetical protein 0.0012 0.0022 0.000000000086296
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0201 0.0304
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0201 0.0252
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.0507 0.7099 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.1264 0.178
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0211 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0436 0.0584
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0288 0.0288
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.0507 0.7099 1
Echinococcus granulosus protein S isoprenylcysteine O methyltransferase 0.0507 0.7099 0.7099
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0201 0.0222
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0218 0.0247
Plasmodium falciparum phd finger protein, putative 0.003 0.0288 0.0405
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.1264 0.1729
Onchocerca volvulus 0.0244 0.3335 1
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0098 0.1246 0.1704
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0022 0.0022
Mycobacterium ulcerans hypothetical protein 0.0026 0.0218 0.0364
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0291 0.0291
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0893 0.1231
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0379 0.0534
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.0507 0.7099 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.1264 0.1264
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0458 0.0458
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0022 0.0031
Brugia malayi Pre-SET motif family protein 0.0214 0.2912 0.4103
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0218 0.0364
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.1264 0.1264
Mycobacterium ulcerans hypothetical protein 0.0024 0.0201 0.0304
Echinococcus multilocularis chromobox protein 1 0.0073 0.0893 0.0893
Schistosoma mansoni chromobox protein 0.0012 0.0022 0.0022
Schistosoma mansoni chromobox protein 0.0073 0.0893 0.0893
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0167 0.0235
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0022 0.0031
Toxoplasma gondii isoprenylcysteine carboxyl methyltransferase (icmt) family protein 0.0507 0.7099 1
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0098 0.1246 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0265 0.0343
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0022 0.000000000086296
Loa Loa (eye worm) hypothetical protein 0.0041 0.0436 0.0614
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0211 0.0266
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.0405
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0022 0.0031
Schistosoma mansoni chromobox protein 0.0012 0.0022 0.0022
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0022 0.0022
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0106 0.137 0.1904
Brugia malayi Bromodomain containing protein 0.003 0.0288 0.0405
Mycobacterium ulcerans hypothetical protein 0.0221 0.3016 1
Echinococcus multilocularis chromobox protein 2 0.0012 0.0022 0.0022
Trypanosoma brucei polo-like protein kinase 0.0099 0.1264 0.1729
Loa Loa (eye worm) helicase 0.0012 0.0022 0.0031
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0201 0.0252
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0098 0.1246 0.1755
Loa Loa (eye worm) hypothetical protein 0.0126 0.1658 0.2335
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0551 0.0747
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Loa Loa (eye worm) RecQ helicase 0.0025 0.0211 0.0297
Echinococcus granulosus Chromo domain 0.0012 0.0022 0.0022
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.1264 0.1754
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0112 0.0049
Loa Loa (eye worm) protein-S isoprenylcysteine O-methyltransferase 0.0507 0.7099 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0291 0.0291
Onchocerca volvulus 0.0012 0.0022 0.000000055502
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.0507 0.7099 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0379 0.0379
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0201 0.5
Plasmodium vivax SET domain protein, putative 0.0031 0.0291 0.038
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0458 0.0458
Trypanosoma cruzi hypothetical protein, conserved 0.0222 0.3031 0.4235
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.1264 0.1754
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0106 0.137 0.1929
Trypanosoma brucei prenyl protein specific carboxyl methyltransferase 0.0507 0.7099 1
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0288 0.0288
Brugia malayi protein-S isoprenylcysteine O-methyltransferase, putative 0.0507 0.7099 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0031
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0022 0.000000000086296
Trypanosoma cruzi hypothetical protein, conserved 0.0222 0.3031 0.4235
Mycobacterium tuberculosis Conserved protein 0.0026 0.0218 0.0411
Loa Loa (eye worm) hypothetical protein 0.0018 0.0112 0.0158
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0031
Brugia malayi hypothetical protein 0.0012 0.0022 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0291 0.0291
Echinococcus multilocularis 0.0507 0.7099 0.7099
Onchocerca volvulus 0.0024 0.0201 0.0538
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0106 0.137 0.1929
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0201 0.0304
Echinococcus granulosus bloom syndrome protein 0.0025 0.0211 0.0211
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0052 0.0599 0.0844
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0032 0.0314 0.0383
Brugia malayi Pre-SET motif family protein 0.0031 0.0291 0.041
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0218 0.0218
Schistosoma mansoni kinase 0.005 0.0569 0.0569
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0201 0.0283
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0098 0.1246 0.1246
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0201 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.1264 0.1754
Trichomonas vaginalis chromobox protein, putative 0.0044 0.048 0.0647
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0031
Echinococcus multilocularis peregrin 0.003 0.0288 0.0288
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0291 0.0291
Echinococcus multilocularis chromobox protein 1 0.0073 0.0893 0.0893
Plasmodium vivax protein-S-isoprenylcysteine O-methyltransferase, putative 0.0507 0.7099 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0275 0.0275
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0201 0.0351
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0135 0.0135
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0092 0.0129
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0201 0.0283
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0291 0.041
Loa Loa (eye worm) hypothetical protein 0.0024 0.0201 0.0283
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0218 0.0364
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0201 0.0304
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0022 0.0031
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0098 0.1246 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0752 0.1059
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0218 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0265 0.0343
Brugia malayi CHD4 protein 0.0012 0.0022 0.0031
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.001 0.0015
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0218 0.0218
Leishmania major hypothetical protein, conserved 0.0222 0.3031 0.4235
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.1264 0.178
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0031 0.03 0.0364
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.1264 0.1754
Plasmodium vivax hypothetical protein, conserved 0.003 0.0288 0.0375
Trypanosoma brucei hypothetical protein, conserved 0.0222 0.3031 0.4235
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0022 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0551 0.0747
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.0507 0.7099 1
Brugia malayi chromobox protein homolog 3 0.0041 0.0436 0.0614
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0211 0.0297
Leishmania major prenyl protein specific carboxyl methyltransferase, putative 0.0507 0.7099 1
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0106 0.137 0.1929
Echinococcus granulosus chromobox protein 2 0.0012 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0022 0.0031
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0112 0.0158
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0022 0.000000000086296
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0094 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.1264 0.1264
Echinococcus granulosus Chromobox protein 3 0.0012 0.0022 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.1264 0.1754
Echinococcus granulosus peregrin 0.003 0.0288 0.0288
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0379 0.0379
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0044 0.003
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0098 0.1246 0.1704
Onchocerca volvulus 0.0032 0.0309 0.0867

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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