TDR Targets

Basic information

Technical information

TDR Targets ID: 804007
Name: methyl 4-[[2-[methyl-[(2-oxo-3,4-dihydro-1H-q uinolin-6-yl)sulfonyl]amino]acetyl]amino]benz oate
MW: 431.462 | Formula: C20H21N3O6S
H donors: 2 H acceptors: 5 LogP: 0.97 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: COC(=O)c1ccc(cc1)NC(=O)CN(S(=O)(=O)c1ccc2c(c1)CCC(=O)N2)C
InChi: 1S/C20H21N3O6S/c1-23(12-19(25)21-15-6-3-13(4-7-15)20(26)29-2)30(27,28)16-8-9-17-14(11-16)5-10-18(24)22-17/h3-4,6-9,11H,5,10,12H2,1-2H3,(H,21,25)(H,22,24)
InChiKey: GFCIYTQKWVGKAU-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

4-[[2-[methyl-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonyl]amino]-1-oxoethyl]amino]benzoic acid methyl ester
4-[[2-[(2-keto-3,4-dihydro-1H-quinolin-6-yl)sulfonyl-methyl-amino]acetyl]amino]benzoic acid methyl ester
methyl 4-[2-[methyl-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonyl]amino]ethanoylamino]benzoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0132	0.0879	0.0873
Schistosoma mansoni	jumonji domain containing protein	0.0085	0.0518	0.0511
Plasmodium vivax	thioredoxin reductase, putative	0.0054	0.0283	0.3159
Schistosoma mansoni	poly [ADP-ribose] polymerase	0.0187	0.1307	0.1301
Trichomonas vaginalis	ankyrin, putative	0.002	0.0014	0.0018
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Brugia malayi	cytoplasmic intermediate filament protein	0.0031	0.01	0.0101
Trichomonas vaginalis	ankyrin repeat domain protein, putative	0.002	0.0013	0.0016
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0107	0.0688	0.0689
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0132	0.0879	0.088
Trypanosoma brucei	trypanothione reductase	0.0054	0.0283	0.212
Onchocerca volvulus		0.0116	0.0757	0.0728
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0028	0.0076	0.0076
Plasmodium vivax	glutathione reductase, putative	0.0054	0.0283	0.3159
Echinococcus granulosus	lamin	0.0058	0.0307	0.0307
Trichomonas vaginalis	conserved hypothetical protein	0.0116	0.0757	0.0953
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0757	0.0817
Schistosoma mansoni	hypothetical protein	0.0116	0.0757	0.075
Loa Loa (eye worm)	thioredoxin reductase	0.0054	0.0283	0.0295
Trichomonas vaginalis	ankyrin repeat domain protein, putative	0.002	0.0013	0.0016
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.0019	0.0007	0.0007
Brugia malayi	hypothetical protein	0.0116	0.0757	0.0767
Echinococcus multilocularis	poly (ADP ribose) polymerase 1	0.0187	0.1307	0.1309
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0076	0.0068
Echinococcus multilocularis	peregrin	0.0033	0.0113	0.0114
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0116	0.0757	0.5768
Giardia lamblia	PHD finger protein 15	0.0033	0.0113	1
Echinococcus granulosus	jumonji domain containing protein	0.0045	0.0212	0.0212
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0757	0.0817
Brugia malayi	Liprin-alpha 2	0.0116	0.0757	0.0767
Trypanosoma cruzi	poly(ADP-ribose) polymerase, putative	0.0187	0.1307	1
Onchocerca volvulus		0.0116	0.0757	0.0728
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0013	0.0016
Plasmodium falciparum	thioredoxin reductase	0.0054	0.0283	0.3674
Loa Loa (eye worm)	glutathione reductase	0.0054	0.0283	0.0295
Brugia malayi	jmjC domain containing protein	0.0107	0.0688	0.0696
Echinococcus granulosus	lysine specific demethylase 5A	0.0039	0.0166	0.0167
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Trichomonas vaginalis	conserved hypothetical protein	0.0116	0.0757	0.0953
Trichomonas vaginalis	mercuric reductase, putative	0.0019	0.0007	0.0009
Mycobacterium ulcerans	flavoprotein disulfide reductase	0.0019	0.0007	0.5
Schistosoma mansoni	ankyrin 23/unc44	0.002	0.0013	0.0006
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0132	0.0879	0.088
Loa Loa (eye worm)	toll and interleukin 1 receptor domain-containing protein isoform f	0.0116	0.0757	0.0817
Brugia malayi	Pre-SET motif family protein	0.0132	0.0879	0.089
Trichomonas vaginalis	unc-44 ankyrins, putative	0.002	0.0013	0.0016
Trichomonas vaginalis	ankyrin repeat and FYVE domain containing protein, putative	0.002	0.0013	0.0016
Schistosoma mansoni	hypothetical protein	0.0116	0.0757	0.075
Trichomonas vaginalis	set domain proteins, putative	0.1044	0.7941	1
Echinococcus granulosus	poly adp ribose polymerase 2	0.0187	0.1307	0.1309
Schistosoma mansoni	hypothetical protein	0.0116	0.0757	0.075
Echinococcus granulosus	E3 ubiquitin protein ligase mib1	0.002	0.0013	0.0013
Leishmania major	huntingtin interacting protein (HIP), putative	0.002	0.0013	0.0206
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0132	0.0879	0.0873
Toxoplasma gondii	thioredoxin reductase	0.0054	0.0283	0.212
Treponema pallidum	NADH oxidase	0.0019	0.0007	0.5
Onchocerca volvulus		0.0058	0.0307	0.0219
Entamoeba histolytica	poly(ADP-ribose) polymerase, putative	0.0187	0.1307	0.5
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0068	0.0059
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0013	0.0016
Plasmodium falciparum	protein kinase, putative	0.0116	0.0757	1
Trypanosoma brucei	poly(adp-ribose) polymerase	0.0187	0.1307	1
Schistosoma mansoni	hypothetical protein	0.0033	0.0113	0.0106
Echinococcus multilocularis	sterile alpha and tir motif containing protein	0.0116	0.0757	0.0758
Loa Loa (eye worm)	hypothetical protein	0.0103	0.0661	0.0712
Brugia malayi	Intermediate filament tail domain containing protein	0.0058	0.0307	0.0311
Trypanosoma cruzi	trypanothione reductase, putative	0.0054	0.0283	0.212
Echinococcus multilocularis	poly (ADP ribose) polymerase	0.0187	0.1307	0.1309
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0107	0.0688	0.0689
Brugia malayi	jmjC domain containing protein	0.0039	0.0166	0.0169
Trichomonas vaginalis	conserved hypothetical protein	0.0116	0.0757	0.0953
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0033	0.0113	0.0114
Entamoeba histolytica	hypothetical protein	0.0187	0.1307	0.5
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0054	0.0283	0.2985
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0757	0.0817
Plasmodium vivax	SET domain protein, putative	0.0132	0.0879	1
Trichomonas vaginalis	multiple ankyrin repeats single kh domain protein, putative	0.002	0.0013	0.0016
Brugia malayi	Patatin-like phospholipase family protein	0.002	0.0013	0.0013
Trichomonas vaginalis	ion channel nompc, putative	0.002	0.0013	0.0016
Loa Loa (eye worm)	jmjC domain-containing protein	0.0067	0.0382	0.0405
Echinococcus multilocularis	lysine specific demethylase 5A	0.0039	0.0166	0.0167
Brugia malayi	intermediate filament protein	0.0058	0.0307	0.0311
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0299	0.0313
Echinococcus multilocularis	tumor protein p63	0.0706	0.5329	0.5336
Brugia malayi	Neurabin protein 1	0.0116	0.0757	0.0767
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0757	0.0817
Loa Loa (eye worm)	hypothetical protein	0.0132	0.0879	0.0952
Trypanosoma cruzi	palmitoyl acyltransferase 1, putative	0.002	0.0013	0.0044
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.0022	0.0028	0.0036
Trypanosoma cruzi	palmitoyl acyltransferase 1, putative	0.002	0.0013	0.0044
Echinococcus multilocularis	jumonji domain containing protein	0.0045	0.0212	0.0212
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0013	0.0016
Trichomonas vaginalis	ankyrin repeat domain protein, putative	0.002	0.0013	0.0016
Onchocerca volvulus		0.0103	0.0661	0.062
Brugia malayi	glutathione reductase	0.0054	0.0283	0.0286
Trypanosoma brucei	palmitoyl acyltransferase 1, putative	0.002	0.0013	0.0044
Echinococcus granulosus	SAM domain containing protein	0.0116	0.0757	0.0758
Schistosoma mansoni	sarm1	0.0116	0.0757	0.075
Echinococcus granulosus	tumor protein p63	0.0706	0.5329	0.5336
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0068	0.0059
Echinococcus multilocularis	liprin beta 1	0.0116	0.0757	0.0758
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0014	0.0018
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0124	0.0823	0.8837
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0013	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Schistosoma mansoni	cellular tumor antigen P53	0.0103	0.0661	0.0655
Schistosoma mansoni	lar interacting protein (lip)-related protein	0.0116	0.0757	0.075
Schistosoma mansoni	lamin	0.0058	0.0307	0.03
Brugia malayi	hypothetical protein	0.0116	0.0757	0.0767
Entamoeba histolytica	hypothetical protein	0.0187	0.1307	0.5
Entamoeba histolytica	hypothetical protein	0.0187	0.1307	0.5
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0917	0.696	0.7643
Echinococcus granulosus	sterile alpha and tir motif containing protein	0.0116	0.0757	0.0758
Echinococcus granulosus	thioredoxin glutathione reductase	0.0054	0.0283	0.0283
Echinococcus multilocularis	lamin dm0	0.0058	0.0307	0.0307
Toxoplasma gondii	poly(ADP-ribose) polymerase catalytic domain-containing protein	0.0187	0.1307	1
Toxoplasma gondii	PHD-finger domain-containing protein	0.0033	0.0113	0.0818
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0019	0.0007	0.5
Toxoplasma gondii	PHD-finger domain-containing protein	0.0033	0.0113	0.0818
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0124	0.0823	0.8837
Loa Loa (eye worm)	tnks protein	0.1194	0.9103	1
Trichomonas vaginalis	2-5A-dependent ribonuclease, putative	0.002	0.0013	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0989	0.7519	0.8257
Echinococcus multilocularis	tankyrase	0.1308	0.9986	1
Loa Loa (eye worm)	intermediate filament protein	0.0058	0.0307	0.0322
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0039	0.0166	0.016
Trichomonas vaginalis	protein phosphatase 1 regulatory subunit 12C, putative	0.002	0.0013	0.0016
Plasmodium falciparum	phd finger protein, putative	0.0033	0.0113	0.1417
Entamoeba histolytica	hypothetical protein	0.0187	0.1307	0.5
Echinococcus multilocularis	SAM domain containing protein	0.0116	0.0757	0.0758
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0127	0.0842	0.0843
Echinococcus granulosus	PHD finger protein rhinoceros	0.0033	0.0113	0.0114
Mycobacterium tuberculosis	Probable oxidoreductase	0.0138	0.093	1
Brugia malayi	Tnks protein	0.1293	0.9875	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0116	0.0757	1
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Echinococcus granulosus	liprin beta 1	0.0116	0.0757	0.0758
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0138	0.093	1
Onchocerca volvulus	Tankyrase homolog	0.1174	0.8951	1
Loa Loa (eye worm)	poly(ADP-ribose) polymerase	0.0187	0.1307	0.1423
Brugia malayi	sterile alpha and TIR motif containing protein 1 isoform a	0.0116	0.0757	0.0767
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0124	0.0823	0.8837
Giardia lamblia	Kinase, NEK	0.002	0.0013	0.0534
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Brugia malayi	Pre-SET motif family protein	0.0917	0.696	0.7048
Leishmania major	trypanothione reductase	0.0054	0.0283	1
Echinococcus granulosus	Ankyrin	0.002	0.0013	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Loa Loa (eye worm)	PHD-finger family protein	0.0033	0.0113	0.0109
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0113	0.0109
Schistosoma mansoni	hypothetical protein	0.0116	0.0757	0.075
Brugia malayi	WGR domain containing protein	0.0187	0.1307	0.1324
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0132	0.0879	0.0873
Trichomonas vaginalis	c2h2 zinc finger protein, putative	0.0116	0.0757	0.0953
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0294	0.0307
Trichomonas vaginalis	ankyrin, putative	0.002	0.0013	0.0016
Echinococcus granulosus	dihydrolipoamide dehydrogenase	0.0019	0.0007	0.0007
Chlamydia trachomatis	dihydrolipoyl dehydrogenase	0.0019	0.0007	0.5
Echinococcus multilocularis	E3 ubiquitin protein ligase mib1	0.002	0.0013	0.0013
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0031	0.01	0.0094
Schistosoma mansoni	lamin	0.0058	0.0307	0.03
Echinococcus granulosus	lamin dm0	0.0058	0.0307	0.0307
Trichomonas vaginalis	ankyrin 2,3/unc44, putative	0.002	0.0013	0.0016
Entamoeba histolytica	zinc finger protein, putative	0.0187	0.1307	0.5
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase, LpdB	0.0019	0.0007	0.5
Onchocerca volvulus		0.0132	0.0879	0.0867
Plasmodium vivax	hypothetical protein, conserved	0.0033	0.0113	0.1219
Brugia malayi	PHD-finger family protein	0.0033	0.0113	0.0115
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0013	0.0016
Giardia lamblia	Kinase, NEK	0.002	0.0013	0.0534
Schistosoma mansoni	lip-related protein (liprin) alpha	0.0116	0.0757	0.075
Trichomonas vaginalis	conserved hypothetical protein	0.0116	0.0757	0.0953
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0058	0.0307	0.0322
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0132	0.0879	0.0873
Mycobacterium tuberculosis	Probable dehydrogenase	0.0124	0.0823	0.8837
Mycobacterium tuberculosis	Probable reductase	0.0124	0.0823	0.8837
Trichomonas vaginalis	unc-44 ankyrins, putative	0.002	0.0013	0.0016
Onchocerca volvulus		0.1045	0.7955	0.8873
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0054	0.0283	0.0283
Onchocerca volvulus		0.0058	0.0307	0.0219
Plasmodium falciparum	glutathione reductase	0.0054	0.0283	0.3674
Echinococcus multilocularis	Ankyrin	0.002	0.0014	0.0014
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0039	0.0166	0.016
Brugia malayi	Bromodomain containing protein	0.0033	0.0113	0.0115
Echinococcus granulosus	tankyrase	0.1308	0.9986	1
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0132	0.0879	0.6709
Trypanosoma cruzi	poly(ADP-ribose) polymerase, putative	0.0187	0.1307	1
Trichomonas vaginalis	glutathione reductase, putative	0.0019	0.0007	0.0009
Brugia malayi	Thioredoxin reductase	0.0054	0.0283	0.0286
Echinococcus granulosus	poly ADP ribose polymerase 1	0.0187	0.1307	0.1309
Brugia malayi	WGR domain containing protein	0.0187	0.1307	0.1324
Echinococcus multilocularis	poly (adp ribose) polymerase 2	0.0187	0.1307	0.1309
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase	0.0019	0.0007	0.5
Echinococcus multilocularis	stromal interaction molecule 1	0.0116	0.0757	0.0758
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0124	0.0823	0.8837
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0138	0.093	1
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0033	0.0113	0.0106
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0019	0.0007	0.5
Loa Loa (eye worm)	jmjC domain-containing protein	0.0039	0.0166	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0187	0.1307	0.1423
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Echinococcus granulosus	histone lysine methyltransferase setb	0.0132	0.0879	0.088
Loa Loa (eye worm)	hypothetical protein	0.0116	0.0757	0.0817
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0138	0.093	1
Echinococcus granulosus	stromal interaction molecule 1	0.0116	0.0757	0.0758
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0013	0.0016
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0014	0.0018
Brugia malayi	coiled-coil like protein 1	0.0116	0.0757	0.0767
Echinococcus multilocularis	lamin	0.0058	0.0307	0.0307
Echinococcus multilocularis	liprin alpha 2	0.0116	0.0757	0.0758
Schistosoma mansoni	poly [ADP-ribose] polymerase	0.0187	0.1307	0.1301
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0028	0.0076	0.0076
Echinococcus multilocularis	musashi	0.0058	0.0307	0.0307
Schistosoma mansoni	intermediate filament proteins	0.0058	0.0307	0.03
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0116	0.0757	0.8598
Trichomonas vaginalis	conserved hypothetical protein	0.0187	0.1307	0.1646
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0307	0.0322
Echinococcus granulosus	peregrin	0.0033	0.0113	0.0114
Echinococcus granulosus	Sterile alpha motif SAM	0.0116	0.0757	0.0758
Echinococcus multilocularis	dihydrolipoamide dehydrogenase	0.0019	0.0007	0.0007
Echinococcus granulosus	liprin alpha 2	0.0116	0.0757	0.0758
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.002	0.0013	0.0016
Echinococcus granulosus	intermediate filament protein	0.0058	0.0307	0.0307

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 804007