Detailed information for compound 807542

Basic information

Technical information
  • TDR Targets ID: 807542
  • Name: 1-[3-acetyl-6-hydroxy-2-(4-methoxyphenyl)-6-m ethyl-4-(phenylamino)-1-cyclohex-3-enyl]ethan one
  • MW: 393.475 | Formula: C24H27NO4
  • H donors: 2 H acceptors: 3 LogP: 3.83 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C1C(=C(Nc2ccccc2)CC(C1C(=O)C)(C)O)C(=O)C
  • InChi: 1S/C24H27NO4/c1-15(26)21-20(25-18-8-6-5-7-9-18)14-24(3,28)23(16(2)27)22(21)17-10-12-19(29-4)13-11-17/h5-13,22-23,25,28H,14H2,1-4H3
  • InChiKey: VVHLLIDVSGDNCN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[3-ethanoyl-6-hydroxy-2-(4-methoxyphenyl)-6-methyl-4-(phenylamino)-1-cyclohex-3-enyl]ethanone
  • STOCK2S-86348
  • BAS 01815067
  • BIM-0009933.P001
  • CBMicro_010139

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0051 0.0507 0.0951
Schistosoma mansoni carbonic anhydrase 0.0045 0.0416 0.0884
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0305 0.0693
Mycobacterium tuberculosis Conserved protein 0.0038 0.0305 0.0693
Brugia malayi thymidylate synthase 0.0107 0.1386 0.2748
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.007 0.0061
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0198 0.2808 0.5656
Schistosoma mansoni carbonic anhydrase-related 0.0045 0.0416 0.0884
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0059 0.0633 0.1209
Brugia malayi Serotonin receptor 0.0023 0.007 0.0058
Brugia malayi beta-lactamase 0.0038 0.0305 0.0539
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0237 0.3407 0.9675
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.002 0.0016 0.0024
Brugia malayi putative neuropeptide receptor 0.0023 0.007 0.0058
Echinococcus granulosus neuropeptide receptor 0.0023 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0081 0.0978 0.0969
Brugia malayi G-protein coupled receptor 0.0023 0.007 0.0058
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.101 0.2177
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.007 0.0107
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.3519 1
Schistosoma mansoni opsin-like receptor 0.0023 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Loa Loa (eye worm) hypothetical protein 0.0038 0.0305 0.0297
Brugia malayi Matrixin family protein 0.0334 0.4933 1
Onchocerca volvulus 0.0038 0.0305 0.0512
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Loa Loa (eye worm) integrin beta-2 0.0073 0.0847 0.0839
Echinococcus multilocularis neutral amino acid transporter A 0.0107 0.1376 0.1773
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.002 0.0016 0.002
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0047 0.0448 0.0577
Loa Loa (eye worm) hypothetical protein 0.0045 0.0416 0.0407
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0088 0.1079 0.1071
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.007 0.0107
Echinococcus granulosus metabotropic glutamate receptor 5 0.0085 0.1036 0.1569
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Trypanosoma brucei Peptide deformylase 2 0.009 0.112 0.3255
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Echinococcus multilocularis integrin alpha 3 0.0068 0.0779 0.1004
Onchocerca volvulus 0.0088 0.1079 0.2199
Loa Loa (eye worm) hypothetical protein 0.0038 0.0305 0.0297
Echinococcus granulosus carbonic anhydrase 0.0045 0.0416 0.063
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0305 0.032
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.007 0.0107
Schistosoma mansoni sodium/calcium exchanger 0.0075 0.0886 0.1908
Chlamydia trachomatis peptide deformylase 0.0237 0.3407 1
Echinococcus multilocularis fmrfamide receptor 0.0023 0.007 0.0091
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0305 0.032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0022 0.006 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Schistosoma mansoni amine GPCR 0.0023 0.007 0.0133
Brugia malayi AKH receptor 0.0023 0.007 0.0058
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.007 0.0058
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Echinococcus multilocularis neuropeptide receptor 0.0023 0.007 0.0091
Brugia malayi Integrin alpha pat-2 precursor 0.0089 0.1105 0.2174
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.007 0.0107
Brugia malayi G protein-coupled receptor 0.0023 0.007 0.0058
Echinococcus multilocularis excitatory amino acid transporter 2 0.0107 0.1376 0.1773
Brugia malayi follicle stimulating hormone receptor 0.0023 0.007 0.0058
Echinococcus multilocularis neutral amino acid transporter A 0.0107 0.1376 0.1773
Echinococcus granulosus Excitatory amino acid transporter 0.0107 0.1376 0.2085
Echinococcus multilocularis excitatory amino acid transporter 2 0.0107 0.1376 0.1773
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0441 0.6601 0.8504
Schistosoma mansoni biogenic amine receptor 0.0023 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0068 0.0765 0.0757
Schistosoma mansoni integrin alpha 0.0089 0.1105 0.2384
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0205 0.0311
Brugia malayi Melatonin receptor type 1A 0.0023 0.007 0.0058
Entamoeba histolytica glycogen phosphorylase, putative 0.0037 0.0288 0.5
Echinococcus multilocularis serotonin receptor 0.0023 0.007 0.0091
Onchocerca volvulus Matrilysin homolog 0.0088 0.1079 0.2199
Mycobacterium ulcerans thymidylate synthase 0.0107 0.1386 0.3951
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.002 0.0016 0.002
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.007 0.0133
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0107 0.1386 0.3484
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0305 0.0645
Echinococcus granulosus orexin receptor type 2 0.0023 0.007 0.0107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0022 0.006 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Brugia malayi ORL1-like opioid receptor 0.0023 0.007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni neuropeptide receptor 0.0023 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0038 0.0305 0.0297
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0021 0.0042 0.0033
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.007 0.0107
Trichomonas vaginalis esterase, putative 0.0038 0.0305 0.032
Echinococcus granulosus Glycosyl transferase family 35 0.0037 0.0288 0.0437
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0305 0.0645
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.0107 0.1376 0.2974
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Echinococcus multilocularis Excitatory amino acid transporter 0.0107 0.1376 0.1773
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0198 0.2808 0.5656
Echinococcus granulosus integrin beta 2 0.0054 0.0552 0.0836
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.007 0.0133
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.007 0.0107
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.002 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0054 0.0045
Loa Loa (eye worm) excitatory amino acid transporter 0.0107 0.1376 0.1369
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Mycobacterium tuberculosis Conserved protein 0.0038 0.0305 0.0693
Schistosoma mansoni carbonic anhydrase-related 0.0045 0.0416 0.0884
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.007 0.0107
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0198 0.2808 0.6088
Brugia malayi beta-lactamase family protein 0.0038 0.0305 0.0539
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0023 0.007 0.0091
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.007 0.0133
Mycobacterium ulcerans hypothetical protein 0.0038 0.0305 0.0717
Echinococcus granulosus adam 0.0128 0.1716 0.26
Echinococcus multilocularis fmrfamide receptor 0.0023 0.007 0.0091
Echinococcus granulosus excitatory amino acid transporter 3 0.0107 0.1376 0.2085
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0107 0.1376 0.1773
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Brugia malayi Hemopexin family protein 0.0124 0.1652 0.3292
Echinococcus granulosus sodium calcium exchanger 0.0075 0.0886 0.1342
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.007 0.0058
Mycobacterium tuberculosis Conserved protein 0.0038 0.0305 0.0693
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.007 0.0107
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0023 0.007 0.0061
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0045 0.0416 0.0764
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0022 0.006 0.0091
Brugia malayi Matrixin family protein 0.0088 0.1079 0.2121
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.007 0.0133
Trypanosoma brucei carbonic anhydrase-like protein 0.0198 0.2808 1
Schistosoma mansoni hypothetical protein 0.0023 0.007 0.0133
Echinococcus granulosus glycogen phosphorylase 0.0037 0.0288 0.0437
Schistosoma mansoni dihydroceramide desaturase 0.0031 0.0197 0.0409
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.007 0.0091
Echinococcus granulosus neutral amino acid transporter A 0.0107 0.1376 0.2085
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0305 0.0297
Schistosoma mansoni amine GPCR 0.0023 0.007 0.0133
Echinococcus granulosus allatostatin A receptor 0.0023 0.007 0.0107
Treponema pallidum polypeptide deformylase (def) 0.0237 0.3407 1
Echinococcus granulosus thymidylate synthase 0.0107 0.1386 0.21
Schistosoma mansoni hypothetical protein 0.0023 0.007 0.0133
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0045 0.0416 0.0764
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0076 0.0901 0.1756
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.007 0.0133
Loa Loa (eye worm) integrin alpha pat-2 0.0138 0.1861 0.1854
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0054 0.0025
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.007 0.0107
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0054 0.0098
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.007 0.0061
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.007 0.0133
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.007 0.0133
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0205 0.0264
Onchocerca volvulus Matrix metalloproteinase homolog 0.0194 0.2748 0.5836
Loa Loa (eye worm) glutamate receptor 0.0026 0.011 0.0101
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.007 0.0107
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.002 0.0016 0.0024
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0065 0.0726 0.156
Loa Loa (eye worm) solute carrier family 8 0.0075 0.0886 0.0878
Giardia lamblia Glycogen phosphorylase 0.0037 0.0288 0.5
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0171
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.009 0.112 0.3255
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.007 0.0107
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.007 0.0133
Brugia malayi Metabotropic glutamate receptor precursor. 0.007 0.08 0.1551
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0074 0.0869 0.187
Brugia malayi Dopamine receptor protein 1 0.0023 0.007 0.0058
Mycobacterium ulcerans hydrolase 0.0107 0.1378 0.3927
Loa Loa (eye worm) glycogen phosphorylase 0.0037 0.0288 0.0279
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.007 0.0061
Echinococcus multilocularis Glycosyl transferase, family 35 0.0037 0.0288 0.0371
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Brugia malayi Sodium/calcium exchanger protein 0.003 0.018 0.0282
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0022 0.006 0.0112
Schistosoma mansoni myosin xvIII 0.0023 0.007 0.0133
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.101 0.2177
Brugia malayi Integrin beta pat-3 precursor 0.0073 0.0847 0.1646
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.007 0.0091
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.007 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.007 0.0107
Echinococcus granulosus neuropeptide receptor 0.0023 0.007 0.0107
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.007 0.0091
Brugia malayi Reprolysin 0.0034 0.0238 0.0401
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.007 0.0133
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0305 0.0717
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0022 0.006 0.0038
Echinococcus multilocularis integrin alpha ps 0.004 0.0335 0.0432
Treponema pallidum glutamate/aspartate transporter 0.0047 0.0448 0.1144
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0107 0.1386 0.4318
Loa Loa (eye worm) hypothetical protein 0.0107 0.1378 0.137
Brugia malayi hypothetical protein 0.0081 0.0978 0.1913
Loa Loa (eye worm) thymidylate synthase 0.0107 0.1386 0.1378
Echinococcus granulosus g protein coupled receptor 0.0023 0.007 0.0107
Brugia malayi ADAMTS-like protease 0.01 0.127 0.251
Mycobacterium tuberculosis Possible exported protein 0.0166 0.2303 0.648
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus multilocularis sodium calcium exchanger 0.0075 0.0886 0.1141
Echinococcus granulosus neutral amino acid transporter A 0.0107 0.1376 0.2085
Echinococcus granulosus g protein coupled receptor 0.0023 0.007 0.0107
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.007 0.0091
Schistosoma mansoni amine GPCR 0.0023 0.007 0.0133
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.007 0.0107
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0065 0.0726 0.0936
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.007 0.0061
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0305 0.0693
Echinococcus granulosus integrin alpha 3 0.0068 0.0779 0.1181
Trypanosoma cruzi Peptide deformylase 2, putative 0.009 0.112 0.3255
Brugia malayi Excitatory amino acid transporter 0.0107 0.1376 0.2729
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0305 0.0693
Mycobacterium tuberculosis Hypothetical protein 0.0051 0.0507 0.1277
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0441 0.6601 1
Echinococcus granulosus adam 17 protease 0.0345 0.5095 0.7717
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.007 0.0133
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.007 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0507 0.4093
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.007 0.0107
Loa Loa (eye worm) metalloprotease 0.0034 0.0238 0.0229
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0034 0.0238 0.0498
Trypanosoma brucei Polypeptide deformylase 1 0.009 0.112 0.3255
Brugia malayi metabotropic glutamate receptor type 2 0.0036 0.0278 0.0482
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0148 0.2022 0.4048
Treponema pallidum glutamate transporter 0.0047 0.0448 0.1144
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0822 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.007 0.0058
Echinococcus granulosus integrin alpha ps 0.004 0.0335 0.0507
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0273 0.3976 0.3971
Echinococcus multilocularis carbonic anhydrase 0.0045 0.0416 0.0535
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0022 0.006 0.0078
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0065 0.0726 0.156
Brugia malayi sulfakinin receptor protein 0.0081 0.0978 0.1913
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0085 0.1036 0.1335
Schistosoma mansoni metabotropic glutamate receptor 0.0059 0.0635 0.1361
Echinococcus multilocularis integrin beta 2 0.0054 0.0552 0.0711
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.007 0.0107
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.007 0.0133
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0305 0.0693
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0198 0.2808 1
Echinococcus granulosus glycogen phosphorylase 0.0037 0.0288 0.0437
Echinococcus granulosus excitatory amino acid transporter 2 0.0107 0.1376 0.2085
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.007 0.0091
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0107 0.1386 0.3823
Brugia malayi angiogenesis inhibito 0.01 0.127 0.251
Schistosoma mansoni opsin-like receptor 0.0023 0.007 0.0133
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0107 0.1376 0.1773
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0026
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0023 0.007 0.0133
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.007 0.0133
Schistosoma mansoni glutamate receptor NMDA 0.002 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.007 0.0107
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.007 0.0107
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0305 0.0693
Echinococcus multilocularis g protein coupled receptor 0.0023 0.007 0.0091
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0107 0.1386 0.3484
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0045 0.0416 0.0407
Schistosoma mansoni adenoreceptor 0.0023 0.007 0.0133
Onchocerca volvulus 0.0038 0.0305 0.0512
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.007 0.0091
Echinococcus granulosus serotonin receptor 0.0023 0.007 0.0107
Brugia malayi beta-lactamase family protein 0.0038 0.0305 0.0539
Echinococcus multilocularis orexin receptor type 2 0.0023 0.007 0.0091
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0107 0.1386 0.4318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0305 0.0297
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.007 0.0107
Schistosoma mansoni neuropeptide receptor 0.0023 0.007 0.0133
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0107 0.1386 0.3484
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0197 0.2782 0.3584
Plasmodium vivax peptide deformylase, putative 0.0237 0.3407 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.007 0.0058
Schistosoma mansoni hypothetical protein 0.0045 0.0416 0.0884
Brugia malayi Matrixin family protein 0.0088 0.1079 0.2121
Mycobacterium leprae PROBABLE HYDROLASE 0.0107 0.1378 0.3458
Echinococcus multilocularis thymidylate synthase 0.0107 0.1386 0.1786
Brugia malayi ADAM-TS Spacer 1 family protein 0.0273 0.3976 0.8044
Loa Loa (eye worm) beta-lactamase 0.0038 0.0305 0.0297
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni amine GPCR 0.0023 0.007 0.0133
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0252 0.3652 0.7925
Loa Loa (eye worm) angiogenesis inhibito 0.0039 0.0316 0.0308
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.002 0.0016 0.0024
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0107 0.1386 0.4318
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.007 0.0061
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0023 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0088 0.1079 0.1071
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Schistosoma mansoni integrin alpha-ps 0.0021 0.0035 0.0056
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0107 0.1378 0.2732
Brugia malayi RE15519p 0.0023 0.007 0.0058
Echinococcus multilocularis somatostatin receptor 0.0023 0.007 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Onchocerca volvulus Glycogen phosphorylase homolog 0.0037 0.0288 0.0475
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.007 0.0091
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0822 1
Onchocerca volvulus 0.0038 0.0305 0.0512
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0107 0.1386 0.2995
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.007 0.0107
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0305 0.032
Loa Loa (eye worm) hypothetical protein 0.0038 0.0305 0.0297
Mycobacterium ulcerans peptide deformylase 0.0237 0.3407 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0305 0.0393
Schistosoma mansoni amine GPCR 0.0023 0.007 0.0133
Brugia malayi Dopamine receptor protein 2 0.0023 0.007 0.0058
Echinococcus granulosus g protein coupled receptor 0.0023 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus Excitatory amino acid transporter 0.0107 0.1376 0.2085
Plasmodium falciparum peptide deformylase 0.0237 0.3407 1
Echinococcus multilocularis disintegrin and metalloproteinase 0.0031 0.0197 0.0254
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0198 0.2808 0.6088
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0022 0.006 0.0112
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.0107 0.1376 0.3795
Brugia malayi GnHR receptor homolog 0.0023 0.007 0.0058
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.007 0.0061
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Chlamydia trachomatis neutral amino acid transporter 0.0047 0.0448 0.1144
Brugia malayi G-protein coupled receptor 0.0023 0.007 0.0058
Echinococcus multilocularis glutamate receptor 2 0.002 0.0016 0.002
Echinococcus multilocularis g protein coupled receptor 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0051 0.0507 0.0805
Trypanosoma cruzi Peptide deformylase 2, putative 0.009 0.112 0.3255
Loa Loa (eye worm) hypothetical protein 0.0045 0.0416 0.0407
Schistosoma mansoni hypothetical protein 0.0023 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0079 0.0942 0.0933
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0252 0.3652 0.4705
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Loa Loa (eye worm) glutamate receptor 0.007 0.08 0.0792
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.007 0.0091
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.002 0.0016 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0022 0.006 0.0091
Echinococcus multilocularis glycogen phosphorylase 0.0037 0.0288 0.0371
Echinococcus multilocularis adam 17 protease 0.0313 0.4606 0.5934
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.007 0.0061
Schistosoma mansoni neuropeptide receptor 0.0023 0.007 0.0133
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus multilocularis sex peptide receptor 0.0023 0.007 0.0091
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.007 0.0061
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.007 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.007 0.0107
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0197 0.2782 0.4214
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.007 0.0091
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.007 0.0107
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0054 0.0082
Loa Loa (eye worm) hypothetical protein 0.0066 0.0743 0.0735
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0198 0.2808 0.2802
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Loa Loa (eye worm) matrixin family protein 0.0334 0.4933 0.4928
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0237 0.3407 1
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0252 0.3652 0.5533
Onchocerca volvulus Excitatory amino acid transporter homolog 0.0107 0.1376 0.2847
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.007 0.0061
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.007 0.0091
Schistosoma mansoni hypothetical protein 0.0124 0.1652 0.3573
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0107 0.1386 0.3244
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Echinococcus granulosus disintegrin and metalloproteinase 0.0031 0.0197 0.0299
Brugia malayi Dopamine receptor 0.0023 0.007 0.0058
Loa Loa (eye worm) hypothetical protein 0.021 0.299 0.2983
Echinococcus multilocularis Excitatory amino acid transporter 0.0107 0.1376 0.1773
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0059 0.0635 0.0818
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0054 0.007
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0313 0.4606 1
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0047 0.0448 0.0955
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.009 0.112 0.3255
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Toxoplasma gondii hypothetical protein 0.0237 0.3407 1
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0061 0.0662 0.0654
Loa Loa (eye worm) hypothetical protein 0.0038 0.0305 0.0297
Schistosoma mansoni integrin beta subunit 0.0043 0.0379 0.0805
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.002 0.0016 0.002
Brugia malayi Matrixin family protein 0.0088 0.1079 0.2121
Echinococcus granulosus carbonic anhydrase 0.0045 0.0416 0.063
Echinococcus multilocularis integrin alpha ps 0.004 0.0335 0.0432
Loa Loa (eye worm) hypothetical protein 0.0034 0.0238 0.0229
Schistosoma mansoni biogenic amine receptor 0.0023 0.007 0.0133
Onchocerca volvulus Matrilysin homolog 0.0317 0.4659 1
Chlamydia trachomatis glycogen phosphorylase 0.0037 0.0288 0.0666
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.007 0.0133
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.007 0.0133
Onchocerca volvulus 0.0107 0.1386 0.2868
Echinococcus multilocularis adam 0.0128 0.1716 0.2211
Echinococcus multilocularis carbonic anhydrase II 0.0198 0.2808 0.3617
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Brugia malayi larval opioid receptor 0.0023 0.007 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0022 0.006 0.0112
Loa Loa (eye worm) hypothetical protein 0.0065 0.0726 0.0718
Echinococcus granulosus neuropeptide s receptor 0.0023 0.007 0.0107
Echinococcus multilocularis glycogen phosphorylase 0.0037 0.0288 0.0371
Schistosoma mansoni histamine h1 receptor 0.0023 0.007 0.0133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Chlamydia trachomatis glutamate symporter 0.0107 0.1376 0.3923
Brugia malayi Matrixin family protein 0.0088 0.1079 0.2121
Loa Loa (eye worm) hypothetical protein 0.0085 0.1036 0.1028
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0076 0.0901 0.0892
Echinococcus multilocularis g protein coupled receptor 0.0023 0.007 0.0091
Echinococcus multilocularis neuropeptide s receptor 0.0023 0.007 0.0091
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.021 0.299 0.6483
Echinococcus multilocularis neuropeptide receptor A26 0.0023 0.007 0.0091
Echinococcus granulosus somatostatin receptor 0.0023 0.007 0.0107
Echinococcus granulosus fmrfamide receptor 0.0023 0.007 0.0107
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.007 0.0091
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0047 0.0448 0.0955
Echinococcus granulosus metabotropic glutamate receptor 2 0.0059 0.0635 0.0962
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Onchocerca volvulus Papilin homolog 0.0079 0.0942 0.1899
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.007 0.0091
Mycobacterium ulcerans beta-lactamase 0.0038 0.0305 0.0717
Echinococcus multilocularis neutral amino acid transporter A 0.0107 0.1376 0.1773
Schistosoma mansoni carbonic anhydrase-related 0.0045 0.0416 0.0884
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0305 0.0463
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0045 0.0416 0.0764
Echinococcus granulosus sex peptide receptor 0.0023 0.007 0.0107
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0068 0.0765 0.1479
Brugia malayi neuropeptide F receptor 0.0023 0.007 0.0058
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.007 0.0133
Echinococcus multilocularis carbonic anhydrase 0.0045 0.0416 0.0535
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0054 0.0082
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0305 0.0717
Echinococcus granulosus carbonic anhydrase 0.0045 0.0416 0.063
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Schistosoma mansoni neuropeptide receptor 0.0023 0.007 0.0133
Schistosoma mansoni glycogen phosphorylase 0.0037 0.0288 0.0607
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.007 0.0133
Onchocerca volvulus 0.0124 0.1652 0.3447
Echinococcus granulosus glutamate receptor 2 0.002 0.0016 0.0024
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0045 0.0416 0.0764
Loa Loa (eye worm) hypothetical protein 0.0095 0.1191 0.1183
Schistosoma mansoni integrin alpha-ps 0.004 0.0335 0.0709
Schistosoma mansoni biogenic amine receptor 0.0023 0.007 0.0133
Echinococcus granulosus excitatory amino acid transporter 2 0.0107 0.1376 0.2085
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0305 0.0693
Loa Loa (eye worm) reprolysin 0.0065 0.0726 0.0718
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0107 0.1378 0.38
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.007 0.0107
Echinococcus granulosus carbonic anhydrase II 0.0198 0.2808 0.4254
Brugia malayi hypothetical protein 0.0126 0.168 0.3348
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.007 0.0107
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus neutral amino acid transporter 0.0107 0.1376 0.2085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0054 0.0098
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0205 0.0264
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.007 0.0107
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0076 0.0901 0.1364
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.007 0.0091
Leishmania major carbonic anhydrase-like protein 0.0198 0.2808 1
Brugia malayi carbohydrate phosphorylase 0.0037 0.0288 0.0504
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0237 0.3407 1
Brugia malayi hypothetical protein 0.0023 0.007 0.0058
Loa Loa (eye worm) matrixin family protein 0.0194 0.2748 0.2742
Echinococcus multilocularis excitatory amino acid transporter 3 0.0107 0.1376 0.1773
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0305 0.0693
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Echinococcus multilocularis neuropeptide receptor 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.007 0.0805 0.0797
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Loa Loa (eye worm) carbonic anhydrase 3 0.0198 0.2808 0.2802
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0045 0.0416 0.0764
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0305 0.0539
Leishmania major polypeptide deformylase-like protein, putative 0.009 0.112 0.3255
Loa Loa (eye worm) hypothetical protein 0.0045 0.0416 0.0407
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.007 0.0107
Toxoplasma gondii hypothetical protein 0.0045 0.0416 0.0355
Loa Loa (eye worm) hypothetical protein 0.0049 0.0479 0.0471
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus integrin alpha ps 0.0019 0.0009 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus sodium:dicarboxylate symporter 0.0107 0.1376 0.2085
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0054 0.007
Schistosoma mansoni hypothetical protein 0.0023 0.007 0.0133
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Schistosoma mansoni metabotropic glutamate receptor 0.0036 0.0278 0.0584
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.007 0.0091
Echinococcus multilocularis serotonin receptor 0.0023 0.007 0.0091
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0198 0.2808 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus hypothetical protein 0.0023 0.007 0.0107
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.007 0.0061
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.007 0.0091
Brugia malayi Serotonin receptor 0.0023 0.007 0.0058
Brugia malayi neuropeptide F receptor 0.0023 0.007 0.0058
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0047 0.0448 0.0577
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0305 0.032
Loa Loa (eye worm) matrix metalloproteinase 0.0088 0.1079 0.1071
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus multilocularis integrin alpha ps 0.0019 0.0009 0.0012
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0076 0.0901 0.116
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.007 0.0107
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.007 0.0091
Echinococcus multilocularis allatostatin A receptor 0.0023 0.007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.007 0.0107
Schistosoma mansoni glycogen phosphorylase 0.0037 0.0288 0.0607
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Mycobacterium ulcerans lipase LipD 0.0038 0.0305 0.0717
Schistosoma mansoni opsin-like receptor 0.0023 0.007 0.0133
Echinococcus multilocularis carbonic anhydrase 0.0045 0.0416 0.0535
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.007 0.0133
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0515 0.7763 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.007 0.0133
Brugia malayi Disintegrin family protein 0.0031 0.0197 0.0318
Loa Loa (eye worm) hypothetical protein 0.0023 0.007 0.0061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.007 0.0091
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0065 0.0726 0.11
Entamoeba histolytica glycogen phosphorylase, putative 0.0037 0.0288 0.5
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0305 0.032
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0126 0.168 0.3633
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.007 0.0091
Echinococcus granulosus g-protein coupled receptor 0.0023 0.007 0.0107
Echinococcus granulosus neuropeptide receptor A26 0.0023 0.007 0.0107
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.007 0.0058
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0021 0.0042 0.0033
Brugia malayi metalloprotease 0.0034 0.0238 0.0401

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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