Detailed information for compound 809782

Basic information

Technical information
  • TDR Targets ID: 809782
  • Name: N'-phenylsulfonylbenzenecarboximidamide
  • MW: 260.312 | Formula: C13H12N2O2S
  • H donors: 1 H acceptors: 2 LogP: 2.42 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: N=C(c1ccccc1)NS(=O)(=O)c1ccccc1
  • InChi: 1S/C13H12N2O2S/c14-13(11-7-3-1-4-8-11)15-18(16,17)12-9-5-2-6-10-12/h1-10H,(H2,14,15)
  • InChiKey: LPXRFQYPABSWTF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N'-phenylsulfonylbenzamidine
  • CBMicro_002381
  • N-[(Z)-Amino(phenyl)methylidene]benzenesulfonamide
  • N-[Phenylsulfonyl]benzenecarboxamidine
  • ZINC03865622
  • CBMicro_008403
  • ST5102007
  • EU-0074141
  • BIM-0008335.P001
  • BIM-0002452.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni amine GPCR 0.0111 0.0074 0.0851
Loa Loa (eye worm) TYRA-2 protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0111 0.0074 0.1931
Schistosoma mansoni hypothetical protein 0.0247 0.0212 0.2446
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0414 0.0382 0.5
Schistosoma mansoni alpha-1 adrenergic receptor 0.0111 0.0074 0.0851
Echinococcus multilocularis g protein coupled receptor 0.0111 0.0074 0.0594
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Toxoplasma gondii glycosyl transferase, group 4 family protein 0.0414 0.0382 0.5
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0969 0.0946 1
Onchocerca volvulus 0.0111 0.0074 0.1931
Onchocerca volvulus 0.0111 0.0074 0.1931
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.0543 0.0513 0.0401
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0111 0.0074 0.0594
Onchocerca volvulus 0.0111 0.0074 0.1931
Brugia malayi RE15519p 0.0111 0.0074 0.1515
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus granulosus 7TM GPCR rhodopsin 0.0111 0.0074 0.0649
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0062 0.0024 0.0059
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus granulosus hypothetical protein 0.0111 0.0074 0.0649
Echinococcus granulosus neuropeptides capa receptor 0.0111 0.0074 0.0649
Onchocerca volvulus 0.0111 0.0074 0.1931
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Echinococcus granulosus somatostatin receptor 0.0111 0.0074 0.0649
Echinococcus multilocularis geminin 0.0136 0.0099 0.087
Echinococcus multilocularis snurportin 1 0.0247 0.0212 0.2089
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0062 0.0024 0.0054
Echinococcus granulosus alpha 1A adrenergic receptor 0.0111 0.0074 0.0649
Brugia malayi Serotonin receptor 0.0111 0.0074 0.1515
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) neuropeptide F receptor 0.0111 0.0074 0.1931
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus granulosus neuropeptide receptor 0.0111 0.0074 0.0649
Schistosoma mansoni biogenic amine receptor 0.0111 0.0074 0.0851
Echinococcus multilocularis neuropeptide FF receptor 2 0.0111 0.0074 0.0594
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) 0.3753 0.3777 0.5
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0111 0.0074 0.1515
Echinococcus multilocularis somatostatin receptor 0.0111 0.0074 0.0594
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Brugia malayi RNA, U transporter 1 0.0066 0.0028 0.0254
Echinococcus multilocularis g protein coupled receptor 0.0111 0.0074 0.0594
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0111 0.0074 0.0649
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0111 0.0074 0.1931
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0111 0.0074 0.0851
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0111 0.0074 0.0649
Brugia malayi Tachykinin-like peptides receptor 99D 0.0111 0.0074 0.1515
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0111 0.0074 0.1515
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0111 0.0074 0.0851
Echinococcus granulosus g protein coupled receptor 0.0111 0.0074 0.0649
Echinococcus granulosus serotonin receptor 0.0111 0.0074 0.0649
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0111 0.0074 0.1515
Loa Loa (eye worm) transcription factor SMAD2 0.0158 0.0122 0.3183
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Brugia malayi neuropeptide F receptor 0.0111 0.0074 0.1515
Echinococcus multilocularis neuropeptide receptor 0.0111 0.0074 0.0594
Echinococcus granulosus snurportin 1 0.0247 0.0212 0.2279
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Schistosoma mansoni hypothetical protein 0.0111 0.0074 0.0851
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis neuropeptide receptor A26 0.0111 0.0074 0.0594
Echinococcus multilocularis tumor protein p63 0.0262 0.0227 0.2249
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis allatostatin A receptor 0.0111 0.0074 0.0594
Schistosoma mansoni opsin-like receptor 0.0111 0.0074 0.0851
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0111 0.0074 0.0594
Brugia malayi Dopamine receptor protein 2 0.0111 0.0074 0.1515
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis neuropeptides capa receptor 0.0111 0.0074 0.0594
Brugia malayi G-protein coupled receptor 0.0111 0.0074 0.1515
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0111 0.0074 0.0649
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0247 0.0212 0.5553
Mycobacterium ulcerans thymidine phosphorylase 0.0543 0.0513 0.0401
Leishmania major UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0414 0.0382 0.5
Schistosoma mansoni neuropeptide f receptor 76f 0.0111 0.0074 0.0851
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Brugia malayi sulfakinin receptor protein 0.0111 0.0074 0.1515
Onchocerca volvulus 0.0414 0.0382 1
Brugia malayi Serotonin receptor 0.0111 0.0074 0.1515
Giardia lamblia Deoxynucleoside kinase 0.0431 0.0399 1
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0111 0.0074 0.0851
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus granulosus biogenic amine 5HT receptor 0.0111 0.0074 0.0649
Echinococcus granulosus tm gpcr rhodopsin 0.0111 0.0074 0.0649
Echinococcus multilocularis thymidine kinase 0.0892 0.0868 0.9164
Schistosoma mansoni biogenic amine receptor 0.0111 0.0074 0.0851
Schistosoma mansoni hypothetical protein 0.0111 0.0074 0.0851
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Echinococcus multilocularis G protein coupled receptor 139 0.0111 0.0074 0.0594
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0111 0.0074 0.0594
Echinococcus multilocularis g-protein coupled receptor 0.0111 0.0074 0.0594
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0111 0.0074 0.0594
Echinococcus granulosus tm gpcr rhodopsin 0.0111 0.0074 0.0649
Echinococcus multilocularis transfer RNA-Ile 0.0892 0.0868 0.9164
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Brugia malayi putative neuropeptide receptor NPR1 0.0111 0.0074 0.1515
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0111 0.0074 0.0851
Plasmodium vivax N-acetylglucosamine-1-phosphate transferase, putative 0.0414 0.0382 0.5
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0414 0.0382 0.5
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0161 0.0124 0.2906
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0062 0.0024 0.0139
Echinococcus granulosus neuropeptides capa receptor 0.0111 0.0074 0.0649
Echinococcus granulosus sex peptide receptor 0.0111 0.0074 0.0649
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0111 0.0074 0.0594
Onchocerca volvulus 0.0111 0.0074 0.1931
Echinococcus granulosus thymidine phosphorylase 0.0543 0.0513 0.5815
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0161 0.0124 0.2906
Onchocerca volvulus 0.0111 0.0074 0.1931
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.0024 0.0274
Echinococcus granulosus thymidine kinase 0.0892 0.0868 1
Echinococcus granulosus neuropeptide receptor 0.0111 0.0074 0.0649
Loa Loa (eye worm) MH2 domain-containing protein 0.0158 0.0122 0.3183
Brugia malayi AKH receptor 0.0111 0.0074 0.1515
Onchocerca volvulus 0.0111 0.0074 0.1931
Schistosoma mansoni hypothetical protein 0.0057 0.0019 0.0216
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0111 0.0074 0.0851
Schistosoma mansoni adenoreceptor 0.0111 0.0074 0.0851
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0062 0.0024 0.0059
Echinococcus multilocularis fmrfamide receptor 0.0111 0.0074 0.0594
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0111 0.0074 0.0594
Onchocerca volvulus 0.0111 0.0074 0.1931
Brugia malayi MH2 domain containing protein 0.0158 0.0122 0.2832
Echinococcus granulosus neuropeptide Y receptor 0.0111 0.0074 0.0649
Onchocerca volvulus 0.0111 0.0074 0.1931
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0111 0.0074 0.0649
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.9873 1 1
Echinococcus granulosus fmrfamide receptor 0.0111 0.0074 0.0649
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0111 0.0074 0.0594
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Schistosoma mansoni hypothetical protein 0.0136 0.0099 0.1145
Echinococcus multilocularis neuropeptide Y receptor 0.0111 0.0074 0.0594
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0111 0.0074 0.0851
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Schistosoma mansoni neuropeptide receptor 0.0111 0.0074 0.0851
Echinococcus granulosus thymidine kinase 0.0892 0.0868 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus granulosus g protein coupled receptor 0.0111 0.0074 0.0649
Echinococcus granulosus rhodopsin orphan GPCR 0.0111 0.0074 0.0649
Loa Loa (eye worm) G-protein coupled receptor 0.0111 0.0074 0.1931
Echinococcus granulosus rhodopsin orphan GPCR 0.0111 0.0074 0.0649
Schistosoma mansoni myosin xvIII 0.0111 0.0074 0.0851
Schistosoma mansoni neuropeptide receptor 0.0111 0.0074 0.0851
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Schistosoma mansoni neuropeptide F-like receptor 0.0111 0.0074 0.0851
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0111 0.0074 0.0649
Echinococcus granulosus neuropeptide receptor A26 0.0111 0.0074 0.0649
Onchocerca volvulus 0.0111 0.0074 0.1931
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.0024 0.0274
Echinococcus multilocularis neuropeptide s receptor 0.0111 0.0074 0.0594
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis g protein coupled receptor 0.0111 0.0074 0.0594
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase 0.3753 0.3777 0.5
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis serotonin receptor 0.0111 0.0074 0.0594
Onchocerca volvulus 0.0111 0.0074 0.1931
Echinococcus granulosus tachykinin peptides receptor 99D 0.0111 0.0074 0.0649
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0161 0.0124 0.2906
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Echinococcus granulosus rhodopsin orphan GPCR 0.0111 0.0074 0.0649
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0111 0.0074 0.0594
Loa Loa (eye worm) deoxynucleoside kinase 0.0161 0.0124 0.3254
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0111 0.0074 0.0649
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0111 0.0074 0.1931
Brugia malayi Deoxynucleoside kinase family protein 0.0161 0.0124 0.2906
Plasmodium falciparum UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0414 0.0382 0.5
Brugia malayi GnHR receptor homolog 0.0111 0.0074 0.1515
Echinococcus multilocularis orexin receptor type 2 0.0111 0.0074 0.0594
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0111 0.0074 0.1515
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0111 0.0074 0.0594
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0161 0.0124 0.1433
Brugia malayi Dopamine receptor protein 1 0.0111 0.0074 0.1515
Echinococcus granulosus g protein coupled receptor 0.0111 0.0074 0.0649
Echinococcus granulosus Thymidine kinase 2 mitochondrial 0.0892 0.0868 1
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase 0.9873 1 0.5
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Onchocerca volvulus 0.0111 0.0074 0.1931
Schistosoma mansoni opsin-like receptor 0.0111 0.0074 0.0851
Brugia malayi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0414 0.0382 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0111 0.0074 0.0851
Brugia malayi Melatonin receptor type 1A 0.0111 0.0074 0.1515
Schistosoma mansoni neuropeptide receptor 0.0111 0.0074 0.0851
Loa Loa (eye worm) G-protein coupled receptor 0.0111 0.0074 0.1931
Echinococcus multilocularis serotonin receptor 0.0111 0.0074 0.0594
Echinococcus granulosus NADH ubiquinone oxidoreductase 42 kDa subunit 0.0161 0.0124 0.1244
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0062 0.0024 0.0622
Echinococcus granulosus rhodopsin orphan GPCR 0.0111 0.0074 0.0649
Schistosoma mansoni hypothetical protein 0.0136 0.0099 0.1145
Mycobacterium ulcerans undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe 0.0414 0.0382 0.0269
Echinococcus multilocularis fmrfamide receptor 0.0111 0.0074 0.0594
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0111 0.0074 0.1515
Echinococcus multilocularis sex peptide receptor 0.0111 0.0074 0.0594
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0161 0.0124 0.2906
Echinococcus granulosus rhodopsin orphan GPCR 0.0111 0.0074 0.0649
Onchocerca volvulus 0.0111 0.0074 0.1931
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Echinococcus granulosus biogenic amine 5HT receptor 0.0111 0.0074 0.0649
Echinococcus multilocularis neuropeptide Y receptor 0.0111 0.0074 0.0594
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0111 0.0074 0.0851
Echinococcus granulosus tm gpcr rhodopsin 0.0111 0.0074 0.0649
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase 0.9873 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0111 0.0074 0.0851
Schistosoma mansoni amine GPCR 0.0111 0.0074 0.0851
Brugia malayi G-protein coupled receptor 0.0111 0.0074 0.1515
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0111 0.0074 0.0851
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Echinococcus granulosus tumor protein p63 0.0262 0.0227 0.2454
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Echinococcus multilocularis thymidine phosphorylase 0.0543 0.0513 0.5329
Loa Loa (eye worm) neuropeptide F receptor 0.0111 0.0074 0.1931
Echinococcus granulosus allatostatin A receptor 0.0111 0.0074 0.0649
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0111 0.0074 0.0851
Schistosoma mansoni hypothetical protein 0.0111 0.0074 0.0851
Schistosoma mansoni opsin-like receptor 0.0111 0.0074 0.0851
Onchocerca volvulus 0.0111 0.0074 0.1931
Echinococcus granulosus orexin receptor type 2 0.0111 0.0074 0.0649
Loa Loa (eye worm) hypothetical protein 0.0414 0.0382 1
Schistosoma mansoni transcription factor LCR-F1 0.0057 0.0019 0.0216
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0111 0.0074 0.0594
Loa Loa (eye worm) melatonin receptor type 1A 0.0111 0.0074 0.1931
Echinococcus multilocularis neuropeptides capa receptor 0.0111 0.0074 0.0594
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0414 0.0382 0.4404
Echinococcus granulosus rhodopsin orphan GPCR 0.0111 0.0074 0.0649
Schistosoma mansoni neuropeptide F-like receptor 0.0111 0.0074 0.0851
Onchocerca volvulus 0.0111 0.0074 0.1931
Brugia malayi G protein-coupled receptor F59B2.13 0.0111 0.0074 0.1515
Onchocerca volvulus Neuropeptide F receptor homolog 0.0111 0.0074 0.1931
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0111 0.0074 0.0851
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Entamoeba histolytica UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0414 0.0382 1
Schistosoma mansoni amine GPCR 0.0111 0.0074 0.0851
Trypanosoma brucei UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0414 0.0382 0.5
Schistosoma mansoni biogenic amine receptor 0.0111 0.0074 0.0851
Schistosoma mansoni histamine h1 receptor 0.0111 0.0074 0.0851
Echinococcus granulosus neuropeptide Y receptor 0.0111 0.0074 0.0649
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0111 0.0074 0.1931
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0111 0.0074 0.0851
Echinococcus multilocularis dro:myosuppressin receptor 0.0111 0.0074 0.0594
Echinococcus multilocularis G-protein coupled receptor, putative 0.0111 0.0074 0.0594
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Brugia malayi follicle stimulating hormone receptor 0.0111 0.0074 0.1515
Schistosoma mansoni thymidine kinase 0.0892 0.0868 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Schistosoma mansoni growth hormone secretagogue receptor 0.0111 0.0074 0.0851
Echinococcus granulosus dro:myosuppressin receptor 0.0111 0.0074 0.0649
Echinococcus granulosus 7tm_1 domain containing protein 0.0111 0.0074 0.0649
Brugia malayi larval opioid receptor 0.0111 0.0074 0.1515
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Brugia malayi ORL1-like opioid receptor 0.0111 0.0074 0.1515
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0111 0.0074 0.0851
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Echinococcus multilocularis thymidine kinase 0.0892 0.0868 0.9164
Echinococcus granulosus geminin 0.0136 0.0099 0.0949
Echinococcus granulosus UDP N acetylglucosamine dolichyl phosphate 0.0414 0.0382 0.4281
Echinococcus granulosus peptide allatostatin:somatostatin 0.0111 0.0074 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Echinococcus multilocularis neuropeptide receptor 0.0111 0.0074 0.0594
Trichomonas vaginalis glucosaminephosphotransferase, putative 0.0414 0.0382 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0111 0.0074 0.0649
Schistosoma mansoni amine GPCR 0.0111 0.0074 0.0851
Onchocerca volvulus 0.0111 0.0074 0.1931
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0111 0.0074 0.0594
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0111 0.0074 0.1931
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0414 0.0382 0.4404
Brugia malayi Dopamine receptor 0.0111 0.0074 0.1515
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0111 0.0074 0.1931
Echinococcus granulosus G protein coupled receptor 139 0.0111 0.0074 0.0649
Echinococcus granulosus neuropeptide FF receptor 2 0.0111 0.0074 0.0649
Brugia malayi putative neuropeptide receptor 0.0111 0.0074 0.1515
Brugia malayi neuropeptide F receptor 0.0111 0.0074 0.1515
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.0024 0.0274
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Schistosoma mansoni hypothetical protein 0.0111 0.0074 0.0851
Brugia malayi hypothetical protein 0.0111 0.0074 0.1515
Echinococcus granulosus neuropeptide s receptor 0.0111 0.0074 0.0649
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Echinococcus granulosus g-protein coupled receptor 0.0111 0.0074 0.0649
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Entamoeba histolytica hypothetical protein 0.0161 0.0124 0.2906
Schistosoma mansoni amine GPCR 0.0111 0.0074 0.0851
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0111 0.0074 0.0594
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0111 0.0074 0.0594
Echinococcus multilocularis UDP N acetylglucosamine dolichyl phosphate 0.0414 0.0382 0.3923
Schistosoma mansoni neuropeptide receptor 0.0111 0.0074 0.0851
Echinococcus multilocularis NADH ubiquinone oxidoreductase 42 kDa subunit 0.0161 0.0124 0.114
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0111 0.0074 0.0851
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0111 0.0074 0.0851
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0111 0.0074 0.0594
Brugia malayi G protein-coupled receptor 0.0111 0.0074 0.1515
Echinococcus multilocularis rhodopsin orphan GPCR 0.0111 0.0074 0.0594
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Giardia lamblia UDP-N-acetylglucosamine-dolichyl-phosphateN-acetylglucosaminephosphotransferase 0.0414 0.0382 0.9388
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0062 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0111 0.0074 0.1931
Onchocerca volvulus 0.0111 0.0074 0.1931

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.