Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0138 | 0.0109 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0279 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0238 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.131 | 0.1284 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0238 | 0.021 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.002 | 0.0017 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Brugia malayi | hypothetical protein | 0.0122 | 0.067 | 0.0643 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0238 | 0.0235 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0397 | 0.222 | 0.2204 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.067 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0238 | 0.0219 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.067 | 0.0642 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0238 | 0.0235 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.131 | 0.1293 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0238 | 0.0209 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0017 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0147 | 0.0127 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0755 | 0.4237 | 0.422 |
Loa Loa (eye worm) | hyaluronidase | 0.1778 | 1 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0397 | 0.222 | 0.2204 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.1778 | 1 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.131 | 0.1293 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.067 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0397 | 0.222 | 0.2217 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.001 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0238 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.067 | 0.0642 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus multilocularis | bifunctional protein NCOAT | 0.1778 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0147 | 0.0127 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0147 | 0.0144 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.0314 | 0.0311 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0252 | 0.0249 |
Brugia malayi | hypothetical protein | 0.0236 | 0.131 | 0.1285 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0238 | 0.0219 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0138 | 0.0135 |
Schistosoma mansoni | Hyaluronidase | 0.1778 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0252 | 0.0224 |
Onchocerca volvulus | 0.0048 | 0.0252 | 0.2144 | |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.001 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0238 | 0.0235 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0017 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0138 | 0.0109 |
Echinococcus granulosus | bifunctional protein NCOAT | 0.1778 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0147 | 0.0144 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0252 | 0.0249 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.