Detailed information for compound 846057

Basic information

Technical information
  • TDR Targets ID: 846057
  • Name: 6-ethoxy-N-(4-fluorophenyl)-3-phenylsulfonylq uinolin-4-amine
  • MW: 422.472 | Formula: C23H19FN2O3S
  • H donors: 1 H acceptors: 3 LogP: 5.52 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc2c(c1)c(Nc1ccc(cc1)F)c(cn2)S(=O)(=O)c1ccccc1
  • InChi: 1S/C23H19FN2O3S/c1-2-29-18-12-13-21-20(14-18)23(26-17-10-8-16(24)9-11-17)22(15-25-21)30(27,28)19-6-4-3-5-7-19/h3-15H,2H2,1H3,(H,25,26)
  • InChiKey: IHSCKKMFBZJNQT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 6-ethoxy-N-(4-fluorophenyl)-3-phenylsulfonyl-quinolin-4-amine
  • 6-ethoxy-N-(4-fluorophenyl)-3-phenylsulfonyl-4-quinolinamine
  • (6-ethoxy-3-phenylsulfonyl-4-quinolyl)-(4-fluorophenyl)amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor E75 0.0032 0.0747 0.0747
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0067 0.2404 0.2404
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Echinococcus multilocularis lamin dm0 0.0027 0.0518 0.0628
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0168 0.7086 0.8603
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.2404 0.2404
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.4305 1
Echinococcus granulosus intermediate filament protein 0.0027 0.0518 0.0727
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Echinococcus granulosus lamin dm0 0.0027 0.0518 0.0727
Brugia malayi tailless protein 0.0032 0.0747 0.0747
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Brugia malayi Nuclear hormone receptor E75 0.0032 0.0747 0.0747
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0032 0.0747 0.0907
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0943 0.6018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Brugia malayi orphan nuclear receptor NR2E1 0.0032 0.0747 0.0747
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0925 0.0925
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.1376 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0067 0.2404 0.3376
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0943 0.0855
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.4305 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.2404 0.3376
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.2404 0.2404
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.0747 0.0737
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.0747 0.105
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0629 0.457
Onchocerca volvulus 0.0094 0.3634 1
Schistosoma mansoni lamin 0.0027 0.0518 0.0628
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0943 0.2191
Loa Loa (eye worm) hypothetical protein 0.0035 0.0925 0.0925
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.2404 0.2918
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0629 0.4011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.2404 0.2404
Echinococcus multilocularis thyroid hormone receptor alpha 0.0192 0.8237 1
Schistosoma mansoni hypothetical protein 0.0168 0.712 0.8643
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.4305 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0747 0.0907
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.4305 0.5
Onchocerca volvulus Bile acid receptor homolog 0.0067 0.2404 0.6052
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.4305 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.1567 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0067 0.2404 0.2404
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0943 0.0943
Brugia malayi nuclear hormone receptor 0.0067 0.2404 0.2404
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.2404 0.2404
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0067 0.2404 0.2918
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.2404 0.2918
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0629 0.5
Loa Loa (eye worm) hypothetical protein 0.0035 0.0925 0.0925
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.4305 0.5
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.1567 0.2553
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.4305 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0925 0.0925
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0747 0.105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.2404 0.2918
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0067 0.2404 0.2404
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0943 0.1325
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0629 0.5
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.4305 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0067 0.2404 0.2404
Brugia malayi nuclear receptor NHR-88 0.0032 0.0747 0.0747
Echinococcus granulosus ecdysone induced protein 78C 0.0067 0.2404 0.3376
Schistosoma mansoni steroid hormone receptor ad4bp 0.0067 0.2404 0.2918
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.1567 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0032 0.0747 0.0907
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.2404 0.2404
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.2404 0.3376
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0067 0.2404 0.2918
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.2685 0.2685
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.6817 0.6817
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0067 0.2404 0.2918
Brugia malayi nuclear receptor RXR 0.0032 0.0747 0.0747
Brugia malayi ecdysone receptor 0.0032 0.0747 0.0747
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0067 0.2404 0.2404
Brugia malayi steroid hormone receptor 0.0067 0.2404 0.2404
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.2685 0.2685
Onchocerca volvulus 0.0067 0.2404 0.6052
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0067 0.2404 0.2918
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0629 0.4011
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.0925 0.1299
Brugia malayi conserved hypotetical protein 0.0032 0.0747 0.0747
Schistosoma mansoni tar DNA-binding protein 0.0073 0.2685 0.3259
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0943 0.0855
Brugia malayi 6-phosphofructokinase 0.0108 0.4305 0.4305
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0943 0.0855
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0067 0.2404 0.2918
Schistosoma mansoni hypothetical protein 0.0125 0.5101 0.6193
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.1376 0.2032
Brugia malayi ecdysteroid receptor 0.0067 0.2404 0.2404
Schistosoma mansoni nuclear receptor 0.0032 0.0747 0.0907
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0067 0.2404 0.2918
Brugia malayi phosphofructokinase 0.0108 0.4305 0.4305
Echinococcus multilocularis tar DNA binding protein 0.0073 0.2685 0.3259
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0032 0.0747 0.0907
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0067 0.2404 0.2404
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0067 0.2404 0.2404
Brugia malayi acetyltransferase, GNAT family protein 0.0168 0.7086 0.7086
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.0747 0.105
Loa Loa (eye worm) nuclear receptor NHR-67 0.0032 0.0747 0.0747
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0943 0.2191
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0518 0.0518
Echinococcus multilocularis musashi 0.0027 0.0518 0.0628
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.0747 0.0737
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0067 0.2404 0.2404
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0943 0.0855
Echinococcus multilocularis nuclear receptor nhr 48 0.0032 0.0747 0.0907
Brugia malayi 6-phosphofructokinase 0.0108 0.4305 0.4305
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0943 0.0855
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Schistosoma mansoni tar DNA-binding protein 0.0073 0.2685 0.3259
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.4305 1
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0518 0.0518
Loa Loa (eye worm) DR-78 0.0032 0.0747 0.0747
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0747 0.0907
Trypanosoma brucei glucosidase, putative 0.0036 0.0943 0.2191
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.1376 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0495 0.0495
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0067 0.2404 0.2918
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0747 0.0907
Onchocerca volvulus 0.0032 0.0747 0.0737
Echinococcus multilocularis ecdysone induced protein 78C 0.0067 0.2404 0.2918
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0032 0.0747 0.105
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0629 0.4011
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0067 0.2404 0.2404
Schistosoma mansoni intermediate filament proteins 0.0027 0.0518 0.0628
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0067 0.2404 0.3376
Brugia malayi hypothetical protein 0.0035 0.0925 0.0925
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Schistosoma mansoni alpha glucosidase 0.0036 0.0943 0.1145
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.4305 0.5226
Brugia malayi nuclear hormone receptor 0.0032 0.0747 0.0747
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.6817 0.8276
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0032 0.0747 0.0747
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0925 0.0925
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.0925 0.0925
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0168 0.7086 0.8603
Echinococcus granulosus tar DNA binding protein 0.0073 0.2685 0.3771
Echinococcus multilocularis FTZ F1 alpha 0.0067 0.2404 0.2918
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.4305 0.4305
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.6817 0.6817
Loa Loa (eye worm) hypothetical protein 0.0035 0.0925 0.0925
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0032 0.0747 0.0747
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0067 0.2404 0.6052
Loa Loa (eye worm) RNA binding protein 0.0073 0.2685 0.2685
Loa Loa (eye worm) hypothetical protein 0.0027 0.0518 0.0518
Echinococcus granulosus nuclear receptor nhr 48 0.0032 0.0747 0.105
Brugia malayi hypothetical protein 0.0032 0.0747 0.0747
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.4305 1
Loa Loa (eye worm) steroid hormone receptor 0.0067 0.2404 0.2404
Schistosoma mansoni thyroid hormone receptor 0.0192 0.8237 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.4305 0.4305
Echinococcus multilocularis lamin 0.0027 0.0518 0.0628
Schistosoma mansoni nuclear receptor nhr-48 0.0032 0.0747 0.0907
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0943 0.0855
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0943 0.0855
Schistosoma mansoni zinc finger protein 0.0032 0.0747 0.0907
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.4305 1
Brugia malayi RNA binding protein 0.0073 0.2685 0.2685
Echinococcus granulosus geminin 0.0168 0.712 1
Schistosoma mansoni lamin 0.0027 0.0518 0.0628
Schistosoma mansoni nuclear hormone receptor 0.0067 0.2404 0.2918
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0067 0.2404 0.2404
Onchocerca volvulus 0.0032 0.0747 0.0737
Schistosoma mansoni hypothetical protein 0.0051 0.1664 0.2021
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.4305 0.6046
Brugia malayi hypothetical protein 0.0035 0.0925 0.0925
Brugia malayi intermediate filament protein 0.0027 0.0518 0.0518
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0067 0.2404 0.2404
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Echinococcus granulosus histone acetyltransferase KAT2B 0.0163 0.6867 0.9645
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.0747 0.0907
Brugia malayi nuclear receptor NHR-67 0.0032 0.0747 0.0747
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0629 0.4011
Brugia malayi TAR-binding protein 0.0073 0.2685 0.2685
Echinococcus granulosus lamin 0.0027 0.0518 0.0727
Brugia malayi photoreceptor-specific nuclear receptor 0.0067 0.2404 0.2404
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0067 0.2404 0.3376
Loa Loa (eye worm) nuclear hormone receptor 0.0032 0.0747 0.0747
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.1567 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0518 0.0518
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0925 0.1122
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.4305 1
Schistosoma mansoni nuclear receptor 0.0032 0.0747 0.0907
Schistosoma mansoni tar DNA-binding protein 0.0073 0.2685 0.3259
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0067 0.2404 0.2404
Loa Loa (eye worm) acetyltransferase 0.0168 0.7086 0.7086
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0032 0.0747 0.0907
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Loa Loa (eye worm) follicle stimulating hormone receptor 0.023 1 1
Brugia malayi Steroid receptor seven-up type 2 0.0067 0.2404 0.2404
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0943 0.1145
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0943 0.0855
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.5101 0.7165
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.4305 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0943 0.2191
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0943 0.0855
Loa Loa (eye worm) hypothetical protein 0.0032 0.0747 0.0747
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.1567 0.2553
Schistosoma mansoni tar DNA-binding protein 0.0073 0.2685 0.3259
Loa Loa (eye worm) hypothetical protein 0.0035 0.0925 0.0925
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Schistosoma mansoni coup transcription factor 0.0067 0.2404 0.2918
Schistosoma mansoni alpha-glucosidase 0.0139 0.5766 0.7
Schistosoma mansoni RAR-like nuclear receptor 0.0067 0.2404 0.2918
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.1567 0.2201
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0943 0.0943
Brugia malayi nuclear receptor NHR-88 0.0067 0.2404 0.2404
Loa Loa (eye worm) phosphofructokinase 0.0108 0.4305 0.4305
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0067 0.2404 0.2918
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0067 0.2404 0.2918
Schistosoma mansoni retinoic acid receptor RXR 0.0067 0.2404 0.2918
Brugia malayi nuclear hormone receptor family member odr-7 0.0032 0.0747 0.0747
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0067 0.2404 0.3376
Echinococcus granulosus FTZ F1 alpha 0.0067 0.2404 0.3376
Echinococcus multilocularis geminin 0.0168 0.712 0.8643
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0943 0.0855
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.0925 0.1122
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.6817 0.8276
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0629 0.4011
Brugia malayi nuclear hormone receptor family member nhr-6 0.0032 0.0747 0.0747
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0943 0.0855
Echinococcus granulosus thyroid hormone receptor alpha 0.0032 0.0747 0.105
Brugia malayi hypothetical protein 0.0032 0.0747 0.0747
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0067 0.2404 0.2404
Schistosoma mansoni hypothetical protein 0.0168 0.712 0.8643
Schistosoma mansoni alpha-glucosidase 0.0139 0.5766 0.7
Brugia malayi nuclear receptor RXR 0.0035 0.0925 0.0925
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.4305 1
Schistosoma mansoni thyroid hormone receptor 0.0192 0.8237 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.5101 0.6193
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.0747 0.0907
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0629 0.457
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.2404 0.2404
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0067 0.2404 0.3376
Loa Loa (eye worm) TAR-binding protein 0.0073 0.2685 0.2685
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.2404 0.2404
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.4305 0.5226
Schistosoma mansoni tar DNA-binding protein 0.0073 0.2685 0.3259
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.6817 0.9575
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.4305 0.5226
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.0925 0.1122
Loa Loa (eye worm) hypothetical protein 0.0067 0.2404 0.2404
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0067 0.2404 0.2404
Onchocerca volvulus Protein ultraspiracle homolog 0.0067 0.2404 0.6052

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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