Detailed information for compound 869583

Basic information

Technical information
  • TDR Targets ID: 869583
  • Name: N-[(2-ethoxyphenyl)methyl]-2-phenylimidazo[2, 1-b][1,3]benzothiazole-6-carboxamide
  • MW: 427.518 | Formula: C25H21N3O2S
  • H donors: 1 H acceptors: 2 LogP: 6.06 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccccc1CNC(=O)c1ccc2c(c1)sc1n2cc(n1)c1ccccc1
  • InChi: 1S/C25H21N3O2S/c1-2-30-22-11-7-6-10-19(22)15-26-24(29)18-12-13-21-23(14-18)31-25-27-20(16-28(21)25)17-8-4-3-5-9-17/h3-14,16H,2,15H2,1H3,(H,26,29)
  • InChiKey: RQTVGPGSJYHDTQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[(2-ethoxyphenyl)methyl]-2-phenyl-imidazo[2,1-b][1,3]benzothiazole-6-carboxamide
  • N-[(2-ethoxyphenyl)methyl]-2-phenyl-6-imidazo[2,1-b][1,3]benzothiazolecarboxamide
  • N-(2-ethoxybenzyl)-2-phenyl-imidazo[2,1-b][1,3]benzothiazole-6-carboxamide
  • E235-1592
  • NCGC00121959-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.4388 0.4054
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0106 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0106 0.0562 0.0562
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.019 0.2253 0.2253
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Entamoeba histolytica cysteine proteinase, putative 0.0575 1 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0106 0.0562 0.0562
Brugia malayi cathepsin L-like cysteine proteinase 0.0106 0.0562 0.0562
Trypanosoma cruzi cysteine protease, putative 0.0296 0.4388 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0296 0.4388 0.4054
Trypanosoma cruzi cruzipain precursor, putative 0.0575 1 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.027 0.3857 0.3857
Entamoeba histolytica cysteine proteinase, putative 0.0296 0.4388 0.4054
Echinococcus granulosus cathepsin b 0.0106 0.0562 0.0562
Brugia malayi cathepsin L-like precursor 0.0385 0.6174 0.6174
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Entamoeba histolytica cysteine protease, putative 0.0575 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0296 0.4388 0.4388
Brugia malayi Cathepsin L-like precursor 0.0575 1 1
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Plasmodium vivax vivapain-2 0.0575 1 1
Plasmodium vivax vivapain-2 0.0575 1 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0106 0.0562 0.0562
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0106 0.0562 0.0562
Echinococcus granulosus cathepsin l1 0.0575 1 1
Echinococcus multilocularis cysteine protease 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Onchocerca volvulus Cathepsin L homolog 0.0575 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0106 0.0562 0.0562
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Onchocerca volvulus 0.0575 1 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0296 0.4388 0.4054
Echinococcus granulosus cathepsin L cysteine protease 0.0296 0.4388 0.4388
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0575 1 1
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Giardia lamblia Cathepsin L-like protease 0.0106 0.0562 0.5
Echinococcus granulosus potassium voltage gated channel subfamily H 0.027 0.3857 0.3857
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0106 0.0562 0.0562
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0106 0.0562 0.0562
Brugia malayi Papain family cysteine protease containing protein 0.0106 0.0562 0.0562
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Echinococcus multilocularis cathepsin L 0.0106 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0385 0.6174 0.6174
Leishmania major cathepsin L-like protease 0.0575 1 1
Giardia lamblia Cathepsin L-like protease 0.0106 0.0562 0.5
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Giardia lamblia Cathepsin L precursor 0.0106 0.0562 0.5
Echinococcus multilocularis cysteine protease 0.0575 1 1
Loa Loa (eye worm) cysteine protease 0.0575 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0296 0.4388 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0385 0.6174 0.5946
Onchocerca volvulus 0.0385 0.6174 0.5946
Echinococcus granulosus cathepsin L cysteine proteinase 0.0575 1 1
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Leishmania major cathepsin L-like protease 0.0575 1 1
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Giardia lamblia Encystation-specific protease 0.0106 0.0562 0.5
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0106 0.0562 0.0562
Echinococcus multilocularis cathepsin b 0.0106 0.0562 0.0562
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0294 0.4356 0.4356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0296 0.4388 0.4388
Brugia malayi cathepsin B-like cysteine proteinase 0.0106 0.0562 0.0562
Entamoeba histolytica cysteine proteinase, putative 0.0296 0.4388 0.4054
Onchocerca volvulus 0.0575 1 1
Giardia lamblia Cathepsin L precursor 0.0106 0.0562 0.5
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0252 0.35 0.3112
Giardia lamblia Cysteine protease 0.0106 0.0562 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0296 0.4388 0.4054
Echinococcus granulosus cathepsin b 0.0106 0.0562 0.0562
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0296 0.4388 0.4388
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.027 0.3857 0.3857
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0575 1 1
Echinococcus granulosus cysteine protease 0.0296 0.4388 0.4388
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Loa Loa (eye worm) hypothetical protein 0.019 0.2253 0.2253
Loa Loa (eye worm) hypothetical protein 0.0106 0.0562 0.0562
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Onchocerca volvulus 0.0575 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Echinococcus multilocularis cathepsin L 0.0296 0.4388 0.4388
Schistosoma mansoni cathepsin F (C01 family) 0.0385 0.6174 0.6174
Leishmania major cathepsin L-like protease 0.0575 1 1
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0106 0.0562 0.5
Trypanosoma cruzi cysteine peptidase, putative 0.0575 1 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0575 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0575 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Echinococcus granulosus cathepsin l1 0.0385 0.6174 0.6174
Leishmania major cathepsin L-like protease 0.0575 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Onchocerca volvulus 0.0575 1 1
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Plasmodium vivax unspecified product 0.0296 0.4388 0.4054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0106 0.0562 0.0562
Leishmania major cathepsin L-like protease 0.0575 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0106 0.0562 0.0562
Echinococcus multilocularis cathepsin b 0.0106 0.0562 0.0562
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0385 0.6174 0.5946
Brugia malayi Cathepsin L-like precursor 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Brugia malayi Cathepsin L-like precursor 0.019 0.2253 0.2253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Giardia lamblia Cysteine protease 0.0106 0.0562 0.5
Brugia malayi Papain family cysteine protease containing protein 0.0296 0.4388 0.4388
Trypanosoma cruzi cysteine peptidase, putative 0.0575 1 1
Giardia lamblia Cysteine protease 0.0106 0.0562 0.5
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Onchocerca volvulus 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0575 1 1
Schistosoma mansoni cathepsin C 0.0106 0.0562 0.0562
Schistosoma mansoni voltage-gated potassium channel 0.0294 0.4356 0.4356
Giardia lamblia Cathepsin L precursor 0.0106 0.0562 0.5
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.027 0.3857 0.3857
Brugia malayi Cathepsin L-like cysteine proteinase 0.0385 0.6174 0.6174
Giardia lamblia Hypothetical protein 0.0106 0.0562 0.5
Onchocerca volvulus Cathepsin F homolog 0.0575 1 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0575 1 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0106 0.0562 0.5
Giardia lamblia Cathepsin L precursor 0.0106 0.0562 0.5
Giardia lamblia Hypothetical protein 0.0106 0.0562 0.5
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Plasmodium vivax unspecified product 0.019 0.2253 0.1791
Loa Loa (eye worm) hypothetical protein 0.0106 0.0562 0.0562
Onchocerca volvulus Cathepsin L homolog 0.0575 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0575 1 1
Leishmania major cathepsin L-like protease 0.0575 1 1
Loa Loa (eye worm) hypothetical protein 0.0385 0.6174 0.6174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.019 0.2253 0.1791
Brugia malayi cathepsin Z-like cysteine proteinase 0.0106 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0575 1 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0106 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0106 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0234 0.314 0.314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Loa Loa (eye worm) cathepsin B 0.0106 0.0562 0.0562
Trypanosoma cruzi cysteine proteinase, putative 0.0296 0.4388 0.4054
Trypanosoma cruzi cysteine peptidase, putative 0.0575 1 1
Schistosoma mansoni cathepsin B (C01 family) 0.0106 0.0562 0.0562
Giardia lamblia Cathepsin L precursor 0.0106 0.0562 0.5
Brugia malayi Cathepsin L-like precursor 0.0385 0.6174 0.6174
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0106 0.0562 0.5
Giardia lamblia Cysteine protease 0.0106 0.0562 0.5
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Loa Loa (eye worm) ctsf protein 0.0575 1 1
Schistosoma mansoni cathepsin s 0.019 0.2253 0.2253
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0106 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.019 0.2253 0.2253
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0252 0.35 0.3112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Loa Loa (eye worm) hypothetical protein 0.0106 0.0562 0.0562
Onchocerca volvulus 0.0575 1 1
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Entamoeba histolytica cysteine proteinase, putative 0.0385 0.6174 0.5946
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0575 1 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0575 1 1
Brugia malayi Cathepsin L-like precursor 0.0575 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0296 0.4388 0.4388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0385 0.6174 0.5946
Entamoeba histolytica cysteine proteinase, putative 0.0296 0.4388 0.4054
Loa Loa (eye worm) hypothetical protein 0.0106 0.0562 0.0562
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Loa Loa (eye worm) fibroinase 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0575 1 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0575 1 1
Plasmodium vivax vivapain-1 0.0296 0.4388 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0575 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0296 0.4388 0.4054
Echinococcus granulosus cathepsin L 0.0106 0.0562 0.0562
Loa Loa (eye worm) papain family cysteine protease containing protein 0.019 0.2253 0.2253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Brugia malayi Cathepsin L-like precursor 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Entamoeba histolytica cysteine protease, putative 0.0296 0.4388 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0575 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0575 1 1
Trypanosoma cruzi cruzipain precursor, putative 0.019 0.2253 0.1791
Entamoeba histolytica cysteine proteinase, putative 0.0575 1 1
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Brugia malayi Cathepsin L-like precursor 0.0385 0.6174 0.6174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0575 1 1
Schistosoma mansoni cathepsin S (C01 family) 0.0106 0.0562 0.0562
Trypanosoma cruzi cysteine proteinase, putative 0.0296 0.4388 0.4054
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0106 0.0562 0.0562
Leishmania major cathepsin L-like protease 0.0575 1 1
Giardia lamblia Cathepsin L precursor 0.0106 0.0562 0.5
Toxoplasma gondii cathepsin CPL 0.0575 1 1
Loa Loa (eye worm) hypothetical protein 0.0106 0.0562 0.0562
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0106 0.0562 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0296 0.4388 0.4054
Onchocerca volvulus 0.0575 1 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0575 1 1
Brugia malayi cathepsin F-like cysteine proteinase 0.019 0.2253 0.2253
Brugia malayi fibroinase precursor 0.0106 0.0562 0.0562
Leishmania major cathepsin L-like protease 0.0575 1 1
Echinococcus granulosus cathepsin L 0.0296 0.4388 0.4388
Plasmodium falciparum cysteine proteinase falcipain 1 0.0296 0.4388 0.4054
Schistosoma mansoni cathepsin F (C01 family) 0.0575 1 1
Loa Loa (eye worm) hypothetical protein 0.019 0.2253 0.2253
Entamoeba histolytica cysteine proteinase 2 0.0296 0.4388 0.4054
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0575 1 1
Brugia malayi cathepsin L precursor 0.0106 0.0562 0.0562
Giardia lamblia Cathepsin B precursor 0.0106 0.0562 0.5
Brugia malayi Cathepsin L-like precursor 0.0575 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0296 0.4388 0.4054
Brugia malayi cathepsin F-like cysteine proteinase 0.0106 0.0562 0.0562
Plasmodium vivax vivapain-3 0.0296 0.4388 0.4054
Leishmania major cysteine peptidase A (CPA) 0.0575 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0575 1 1
Loa Loa (eye worm) hypothetical protein 0.0385 0.6174 0.6174

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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