TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 331.218 | Formula: C13H12Cl2N2O2S
H donors: 1 H acceptors: 2 LogP: 3.33 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: COCCNC(=O)c1csc(n1)c1cccc(c1Cl)Cl
InChi: 1S/C13H12Cl2N2O2S/c1-19-6-5-16-12(18)10-7-20-13(17-10)8-3-2-4-9(14)11(8)15/h2-4,7H,5-6H2,1H3,(H,16,18)
InChiKey: MEYFEGGVEZFFFS-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Protein kinase domain containing protein	0.0083	0.0015	0.0015
Loa Loa (eye worm)	TK/FAK protein kinase	0.0804	0.0712	0.0712
Trypanosoma brucei	protein kinase, putative	0.0081	0.0013	0.0013
Echinococcus multilocularis	discoidin domain containing receptor 2	0.0152	0.0081	0.0081
Echinococcus granulosus	tyrosine kinase	0.0083	0.0015	0.0015
Loa Loa (eye worm)	hypothetical protein	0.4549	0.4331	0.4331
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0117	0.0048	0.0048
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0328	0.0252	1
Toxoplasma gondii	PA14 domain-containing protein	0.0152	0.0081	0.0187
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0275	0.0201	0.0201
Brugia malayi	SH2 domain containing protein	0.0083	0.0015	0.0015
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0275	0.0201	0.0201
Trypanosoma cruzi	cytochrome P450, putative	0.0103	0.0034	0.0034
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0104	0.0036	0.0036
Echinococcus multilocularis	discoidin domain receptor	0.0152	0.0081	0.0081
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Trichomonas vaginalis	set domain proteins, putative	0.0266	0.0192	0.6478
Schistosoma mansoni	nephrin	0.0079	0.0011	0.0079
Schistosoma mansoni	tyrosine kinase	0.0126	0.0057	0.04
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0104	0.0036	0.0036
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0275	0.0201	0.0201
Echinococcus multilocularis	c Jun NH2 terminal kinase	0.0758	0.0667	0.0667
Echinococcus multilocularis	tyrosine protein kinase shark	0.0083	0.0015	0.0015
Entamoeba histolytica	protein kinase, putative	0.0088	0.002	0.0277
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0187	0.0115	0.0115
Brugia malayi	Cytochrome P450 family protein	0.0103	0.0034	0.0034
Entamoeba histolytica	protein kinase, putative	0.0187	0.0115	0.4282
Echinococcus granulosus	NCK adaptor protein	0.0088	0.002	0.002
Brugia malayi	Pre-SET motif family protein	0.0234	0.016	0.016
Echinococcus granulosus	discoidin domain containing receptor 2	0.0152	0.0081	0.0081
Loa Loa (eye worm)	CYP4Cod1	0.0103	0.0034	0.0034
Brugia malayi	Tyrosine-protein kinase abl-1	0.07	0.0611	0.0611
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0083	0.0015	0.0015
Loa Loa (eye worm)	SRC-1	0.0275	0.0201	0.0201
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0079	0.0011	0.0011
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0081	0.0013	0.0013
Giardia lamblia	Fructose-bisphosphate aldolase	0.0328	0.0252	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0318	0.0242	0.0242
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0275	0.0201	0.0201
Echinococcus multilocularis	Coagulation factor 5 8 type, C terminal	0.0152	0.0081	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0104	0.0036	0.0036
Schistosoma mansoni	vesicular amine transporter	0.0079	0.0011	0.0079
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0079	0.0011	0.0079
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0232	0.0158	0.0158
Echinococcus granulosus	protein tyrosine kinase	0.0795	0.0703	0.0703
Brugia malayi	latrophilin 2 splice variant baaae	0.0071	0.0004	0.0004
Leishmania major	cytochrome p450-like protein	0.0103	0.0034	0.0034
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Loa Loa (eye worm)	cytochrome P450 family protein	0.0103	0.0034	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0083	0.0015	0.0015
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	1.0416	1	1
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0081	0.0013	0.003
Mycobacterium tuberculosis	Possible arabinofuranosyltransferase AftD	0.0152	0.0081	0.9058
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Echinococcus multilocularis	discoidin domain containing receptor 2	0.0152	0.0081	0.0081
Schistosoma mansoni	protein kinase	0.0081	0.0013	0.0091
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.2856	0.2694	0.2694
Loa Loa (eye worm)	hypothetical protein	0.0611	0.0525	0.0525
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.016	0.009	1
Onchocerca volvulus		0.0087	0.0018	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0083	0.0015	0.0015
Echinococcus granulosus	c src tyrosine kinase	0.0126	0.0057	0.0057
Toxoplasma gondii	hypothetical protein	0.4549	0.4331	1
Schistosoma mansoni	tyrosine kinase	0.0083	0.0015	0.0103
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0079	0.0011	0.0079
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0232	0.0158	0.0158
Schistosoma mansoni	discoidin domain receptor	0.0152	0.0081	0.0571
Trypanosoma brucei	cytochrome P450, putative	0.0103	0.0034	0.0034
Brugia malayi	Cytochrome P450 family protein	0.024	0.0166	0.0166
Loa Loa (eye worm)	TK/DDR protein kinase	0.1096	0.0994	0.0994
Schistosoma mansoni	growth factor receptor-bound protein	0.0088	0.002	0.0142
Echinococcus granulosus	tyrosine kinase	0.0232	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Treponema pallidum	fructose-bisphosphate aldolase	0.0328	0.0252	0.5
Echinococcus granulosus	c-Jun N-terminal kinases	0.0758	0.0667	0.0667
Echinococcus multilocularis	nuclear receptor 2C2 associated protein	0.0152	0.0081	0.0081
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0103	0.0034	0.3843
Schistosoma mansoni	discoidin domain receptor	0.0152	0.0081	0.0571
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0088	0.002	0.002
Loa Loa (eye worm)	hypothetical protein	0.0088	0.002	0.002
Toxoplasma gondii	F5/8 type C domain-containing protein	0.0152	0.0081	0.0187
Plasmodium falciparum	LCCL domain-containing protein	0.0152	0.0081	1
Schistosoma mansoni	tyrosine kinase	0.0126	0.0057	0.04
Loa Loa (eye worm)	CMGC/MAPK/P38 protein kinase	1.0416	1	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0083	0.0015	0.0071
Toxoplasma gondii	F5/8 type C domain-containing protein	0.0152	0.0081	0.0187
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0275	0.0201	0.0201
Trypanosoma cruzi	cytochrome P450, putative	0.0103	0.0034	0.0034
Brugia malayi	Protein kinase domain containing protein	0.0083	0.0015	0.0015
Leishmania major	protein kinase, putative	0.0081	0.0013	0.0013
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0275	0.0201	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0083	0.0015	0.0015
Schistosoma mansoni	hypothetical protein	0.0071	0.0004	0.0025
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0081	0.0013	0.0013
Brugia malayi	Cytochrome P450 family protein	0.0103	0.0034	0.0034
Echinococcus multilocularis	discoidin domain containing receptor 2	0.0152	0.0081	0.0081
Schistosoma mansoni	tyrosine kinase	0.0275	0.0201	0.1412
Loa Loa (eye worm)	inward rectifying k channel family protein 1	0.4549	0.4331	0.4331
Echinococcus granulosus	tyrosine protein kinase HCK	0.0187	0.0115	0.0115
Loa Loa (eye worm)	TK protein kinase	0.0232	0.0158	0.0158
Echinococcus granulosus	tyrosine protein kinase shark	0.0083	0.0015	0.0015
Echinococcus granulosus	tyrosine protein kinase Blk	0.0232	0.0158	0.0158
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0083	0.0015	0.0015
Echinococcus granulosus	Coagulation factor 5 8 type C terminal	0.0152	0.0081	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0152	0.0081	0.0081
Loa Loa (eye worm)	hypothetical protein	0.1096	0.0994	0.0994
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.016	0.009	1
Loa Loa (eye worm)	hypothetical protein	0.4549	0.4331	0.4331
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0081	0.0013	0.0013
Echinococcus granulosus	discoidin domain containing receptor 2	0.0152	0.0081	0.0081
Echinococcus multilocularis	protein tyrosine kinase	0.0795	0.0703	0.0703
Schistosoma mansoni	nck2/grb4	0.0088	0.002	0.0142
Echinococcus granulosus	roundabout 2	0.0079	0.0011	0.0011
Loa Loa (eye worm)	hypothetical protein	0.4549	0.4331	0.4331
Leishmania major	mitogen-activated protein kinase 3, putative,map kinase 3, putative	1.0416	1	1
Mycobacterium leprae	PROBABLE CONSERVED TRANSMEMBRANE PROTEIN	0.0152	0.0081	0.9058
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0126	0.0057	0.0057
Schistosoma mansoni	btb and poz domain-containing protein	0.0152	0.0081	0.0571
Toxoplasma gondii	F5/8 type C domain-containing protein	0.0152	0.0081	0.0187
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0088	0.002	0.002
Echinococcus granulosus	activin receptor type	0.0081	0.0013	0.0013
Echinococcus multilocularis	mitogen activated protein kinase 14	1.0416	1	1
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0275	0.0201	0.0201
Brugia malayi	Sex muscle abnormal protein 5	0.0088	0.002	0.002
Echinococcus multilocularis	activin receptor type	0.0081	0.0013	0.0013
Echinococcus granulosus	mitogen activated protein kinase 14	1.0416	1	1
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	1.0416	1	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Loa Loa (eye worm)	hypothetical protein	0.1209	0.1103	0.1103
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0194	0.0122	0.0122
Brugia malayi	Stress-activated protein kinase jnk-1	0.0758	0.0667	0.0667
Echinococcus multilocularis	mitogen activated protein kinase 14	1.0416	1	1
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0232	0.0158	0.0158
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Schistosoma mansoni	tyrosine kinase	0.0795	0.0703	0.4948
Brugia malayi	Variant SH3 domain containing protein	0.0088	0.002	0.002
Schistosoma mansoni	tyrosine kinase	0.0275	0.0201	0.1412
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0275	0.0201	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0152	0.0081	0.0081
Schistosoma mansoni	cell adhesion molecule	0.0079	0.0011	0.0079
Echinococcus granulosus	tyrosine protein kinase Srms	0.0083	0.0015	0.0015
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0232	0.0158	0.0158
Schistosoma mansoni	serine/threonine protein kinase	0.0758	0.0667	0.4698
Echinococcus multilocularis	mitogen activated protein kinase 11	1.0416	1	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0088	0.002	0.002
Loa Loa (eye worm)	hypothetical protein	0.0071	0.0004	0.0004
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.1582	0.1464	0.1464
Trypanosoma brucei	mitogen-activated protein kinase 3, putative	1.0416	1	1
Brugia malayi	Tyrosine-protein kinase abl-1	0.0926	0.083	0.083
Brugia malayi	hypothetical protein	0.0079	0.0011	0.0011
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0081	0.0013	0.0013
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0117	0.0048	0.0048
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0126	0.0057	0.0057
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0234	0.016	0.016
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Echinococcus granulosus	tyrosine protein kinase ABL1	0.1582	0.1464	0.1464
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0088	0.002	0.0142
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0194	0.0122	0.0122
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Echinococcus multilocularis	roundabout 2	0.0079	0.0011	0.0011
Plasmodium vivax	LCCL domain-containing protein	0.0152	0.0081	0.5
Schistosoma mansoni	septate junction protein	0.0152	0.0081	0.0571
Brugia malayi	Protein kinase domain containing protein	0.0083	0.0015	0.0015
Schistosoma mansoni	serine/threonine protein kinase	0.0082	0.0014	0.0095
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0079	0.0011	0.0011
Brugia malayi	Fibronectin type III domain containing protein	0.0079	0.0011	0.0011
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0081	0.0013	0.0013
Loa Loa (eye worm)	TK protein kinase	0.0187	0.0115	0.0115
Schistosoma mansoni	tyrosine kinase	0.0083	0.0015	0.0103
Echinococcus granulosus	discoidin domain receptor	0.1209	0.1103	0.1103
Echinococcus granulosus	growth factor receptor bound protein 2	0.0088	0.002	0.002
Brugia malayi	Variant SH3 domain containing protein	0.0088	0.002	0.002
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0079	0.0011	0.0011
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0275	0.0201	0.0201
Schistosoma mansoni	protein kinase	0.0081	0.0013	0.0091
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0275	0.0201	0.0201
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0275	0.0201	0.0201
Brugia malayi	SRC-1	0.0275	0.0201	0.0201
Schistosoma mansoni	hypothetical protein	0.0152	0.0081	0.0571
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0104	0.0036	0.0036
Brugia malayi	hypothetical protein	0.0083	0.0015	0.0015
Echinococcus multilocularis	NCK adaptor protein	0.0088	0.002	0.002
Echinococcus multilocularis	mitogen activated protein kinase 11	1.0416	1	1
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Echinococcus multilocularis	c src tyrosine kinase	0.0126	0.0057	0.0057
Echinococcus granulosus	twitchin	0.0122	0.0053	0.0053
Loa Loa (eye worm)	cytochrome P450 family protein	0.0103	0.0034	0.0034
Brugia malayi	Protein kinase domain containing protein	0.1247	0.114	0.114
Schistosoma mansoni	tyrosine kinase	0.1537	0.142	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0275	0.0201	0.0201
Echinococcus multilocularis	tyrosine protein kinase Abl	0.07	0.0611	0.0611
Echinococcus granulosus	Immunoglobulin	0.0079	0.0011	0.0011
Echinococcus granulosus	mitogen activated protein kinase 11	1.0416	1	1
Schistosoma mansoni	adapter molecule crk	0.0088	0.002	0.0142
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0275	0.0201	0.0201
Loa Loa (eye worm)	TK/ABL protein kinase	0.1582	0.1464	0.1464
Schistosoma mansoni	growth factor receptor-bound protein	0.0088	0.002	0.0142
Echinococcus granulosus	defective proboscis extension response	0.0079	0.0011	0.0011
Echinococcus multilocularis	tyrosine kinase	0.0083	0.0015	0.0015
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0328	0.0252	1
Onchocerca volvulus		0.1247	0.114	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0275	0.0201	0.0201
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0275	0.0201	0.0201
Echinococcus multilocularis	Immunoglobulin	0.0079	0.0011	0.0011
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Loa Loa (eye worm)	TK/FER protein kinase	0.0083	0.0015	0.0015
Onchocerca volvulus		0.0266	0.0192	0.1573
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.016	0.009	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0328	0.0252	1
Brugia malayi	protein-tyrosine kinase	0.0232	0.0158	0.0158
Brugia malayi	SH2 domain containing protein	0.0083	0.0015	0.0015
Brugia malayi	Protein kinase domain containing protein	0.0804	0.0712	0.0712
Plasmodium vivax	LCCL domain-containing protein	0.0152	0.0081	0.5
Echinococcus multilocularis	Immunoglobulin	0.0079	0.0011	0.0011
Echinococcus granulosus	discoidin domain containing receptor 2	0.0152	0.0081	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Loa Loa (eye worm)	CMGC/MAPK/JNK protein kinase	0.0758	0.0667	0.0667
Schistosoma mansoni	dock	0.0152	0.0081	0.0571
Onchocerca volvulus		0.0152	0.0081	0.0591
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0126	0.0057	0.04
Schistosoma mansoni	protein kinase	0.0081	0.0013	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0088	0.002	0.0277
Plasmodium falciparum	LCCL domain-containing protein	0.0152	0.0081	1
Echinococcus multilocularis	neuroglian	0.0079	0.0011	0.0011
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0275	0.0201	0.0201
Loa Loa (eye worm)	cytochrome P450 family protein	0.024	0.0166	0.0166
Echinococcus granulosus	neuroglian	0.0079	0.0011	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0011	0.0011

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 879671