TDR Targets

Basic information

Technical information

TDR Targets ID: 881529
Name: 2-methylpropyl 3-[(3-ethoxycarbonylphenyl)met hyl]-5-methyl-4-oxothieno[5,4-d]pyrimidine-6- carboxylate
MW: 428.501 | Formula: C22H24N2O5S
H donors: 0 H acceptors: 3 LogP: 4.5 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: CCOC(=O)c1cccc(c1)Cn1cnc2c(c1=O)c(C)c(s2)C(=O)OCC(C)C
InChi: 1S/C22H24N2O5S/c1-5-28-21(26)16-8-6-7-15(9-16)10-24-12-23-19-17(20(24)25)14(4)18(30-19)22(27)29-11-13(2)3/h6-9,12-13H,5,10-11H2,1-4H3
InChiKey: ZGWNZLDENMLZBJ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

isobutyl 3-[(3-ethoxycarbonylphenyl)methyl]-5-methyl-4-oxo-thieno[5,4-d]pyrimidine-6-carboxylate
3-[(3-ethoxycarbonylphenyl)methyl]-5-methyl-4-oxo-6-thieno[5,4-d]pyrimidinecarboxylic acid isobutyl ester
3-(3-carbethoxybenzyl)-4-keto-5-methyl-thieno[5,4-d]pyrimidine-6-carboxylic acid isobutyl ester
2-methylpropyl 3-[(3-ethoxycarbonylphenyl)methyl]-5-methyl-4-oxo-thieno[5,4-d]pyrimidine-6-carboxylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	neutral amino acid transporter	0.0122	0.1334	0.3313
Onchocerca volvulus		0.0026	0.0069	0.0346
Schistosoma mansoni	retinoic acid receptor RXR	0.0026	0.0069	0.0246
Brugia malayi	laminin-like protein K08C7.3 precursor	0.005	0.0395	0.0395
Trypanosoma cruzi	PAB1-binding protein , putative	0.0051	0.0403	0.0403
Echinococcus multilocularis	tissue type plasminogen activator	0.0022	0.0023	0.0058
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Onchocerca volvulus	Bile acid receptor homolog	0.0026	0.0069	0.0346
Schistosoma mansoni	hypothetical protein	0.0035	0.0189	0.0678
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Loa Loa (eye worm)	hypothetical protein	0.0399	0.498	0.498
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0023	0.0023
Echinococcus multilocularis	sodium:dicarboxylate symporter	0.0054	0.0442	0.1097
Schistosoma mansoni	nuclear hormone receptor	0.0026	0.0069	0.0246
Echinococcus multilocularis	Mitotic checkpoint protein PRCC, C terminal	0.0122	0.1332	0.3308
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.012	0.1308	0.1308
Brugia malayi	Fli-1 protein	0.0232	0.2789	0.2789
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0026	0.0069	0.0069
Loa Loa (eye worm)	hypothetical protein	0.01	0.1054	0.1054
Leishmania major	C-8 sterol isomerase-like protein	0.078	1	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0026	0.0069	0.0069
Schistosoma mansoni	solute carrier family 1 (glial high affinity glutamate transporter	0.0122	0.1334	0.4784
Onchocerca volvulus		0.0027	0.0089	0.0499
Onchocerca volvulus	Protein ultraspiracle homolog	0.0026	0.0069	0.0346
Onchocerca volvulus		0.0048	0.036	0.2572
Leishmania major	hypothetical protein, conserved	0.0051	0.0403	0.0403
Toxoplasma gondii	LsmAD domain-containing protein	0.0051	0.0403	0.2953
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0026	0.0069	0.0246
Mycobacterium tuberculosis	Probable C4-dicarboxylate-transport transmembrane protein DctA	0.0122	0.1334	1
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0026	0.0069	0.0246
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.012	0.1308	0.3247
Loa Loa (eye worm)	fli-1 protein	0.0232	0.2789	0.2789
Echinococcus granulosus	excitatory amino acid transporter 3	0.0122	0.1334	0.3313
Loa Loa (eye worm)	hypothetical protein	0.005	0.0395	0.0395
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.01	0.1054	0.3777
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.01	0.1054	0.3777
Loa Loa (eye worm)	TK/ROR protein kinase	0.0022	0.0023	0.0023
Brugia malayi	steroid hormone receptor	0.0026	0.0069	0.0069
Echinococcus multilocularis	pikachurin	0.005	0.0395	0.098
Echinococcus multilocularis	neurogenic locus notch protein	0.005	0.0395	0.098
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0026	0.0069	0.0069
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0026	0.0069	0.017
Onchocerca volvulus		0.0027	0.0089	0.0499
Echinococcus multilocularis	FTZ F1 alpha	0.0026	0.0069	0.017
Schistosoma mansoni	coup transcription factor	0.0026	0.0069	0.0246
Brugia malayi	photoreceptor-specific nuclear receptor	0.0026	0.0069	0.0069
Echinococcus granulosus	sodium:chloride dependent neurotransmitter	0.01	0.1054	0.2615
Echinococcus granulosus	neutral amino acid transporter A	0.0122	0.1334	0.3313
Schistosoma mansoni	dihydropyridine-sensitive l-type calcium channel	0.0063	0.0566	0.2029
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0495	0.0495
Echinococcus granulosus	GA binding protein alpha chain	0.0077	0.0739	0.1834
Echinococcus multilocularis	lamin	0.0027	0.0089	0.022
Echinococcus multilocularis	excitatory amino acid transporter 2	0.0122	0.1334	0.3313
Schistosoma mansoni	aldehyde dehydrogenase	0.012	0.1308	0.4689
Schistosoma mansoni	ets-related	0.0232	0.2789	1
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0082	0.0082
Echinococcus granulosus	excitatory amino acid transporter 2	0.0122	0.1334	0.3313
Plasmodium falciparum	ataxin-2 like protein, putative	0.0051	0.0403	1
Loa Loa (eye worm)	hypothetical protein	0.078	1	1
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.012	0.1308	0.9802
Entamoeba histolytica	hypothetical protein	0.0035	0.0189	1
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0593	0.0593
Loa Loa (eye worm)	hypothetical protein	0.005	0.0395	0.0395
Echinococcus multilocularis	neutral amino acid transporter A	0.0122	0.1334	0.3313
Schistosoma mansoni	serine-rich repeat protein	0.0068	0.0623	0.2233
Brugia malayi	Steroid receptor seven-up type 2	0.0026	0.0069	0.0069
Brugia malayi	EGF-like domain containing protein	0.005	0.0395	0.0395
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0035	0.0189	0.0469
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0403	0.0403
Echinococcus multilocularis	sodium:dicarboxylate symporter	0.0122	0.1334	0.3313
Echinococcus multilocularis	tumor protein p63	0.0326	0.4028	1
Plasmodium falciparum	ataxin-2 like protein, putative	0.0051	0.0403	1
Echinococcus granulosus	FTZ F1 alpha	0.0026	0.0069	0.017
Schistosoma mansoni	thyroid hormone receptor	0.0147	0.167	0.5985
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0026	0.0069	0.0069
Plasmodium vivax	ataxin-2 like protein, putative	0.0051	0.0403	1
Brugia malayi	Protein kinase domain containing protein	0.0022	0.0023	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0026	0.0069	0.0069
Schistosoma mansoni	aldehyde dehydrogenase	0.012	0.1308	0.4689
Entamoeba histolytica	hypothetical protein	0.0035	0.0189	1
Mycobacterium ulcerans	aldehyde dehydrogenase	0.012	0.1308	1
Toxoplasma gondii	aldehyde dehydrogenase	0.012	0.1308	1
Brugia malayi	Nuclear hormone receptor-like 1	0.0026	0.0069	0.0069
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0026	0.0069	0.017
Echinococcus granulosus	voltage dependent calcium channel subunit	0.0131	0.1457	0.3617
Schistosoma mansoni	slit	0.005	0.0395	0.1416
Entamoeba histolytica	hypothetical protein	0.0035	0.0189	1
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0026	0.0069	0.0246
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0026	0.0069	0.0069
Echinococcus multilocularis	Excitatory amino acid transporter	0.0122	0.1334	0.3313
Brugia malayi	Thrombospondin N-terminal -like domain containing protein	0.005	0.0395	0.0395
Echinococcus granulosus	lamin	0.0027	0.0089	0.022
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0147	0.167	0.4144
Echinococcus granulosus	neurogenic locus notch protein	0.005	0.0395	0.098
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0027	0.0089	0.0089
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0035	0.0189	0.0469
Entamoeba histolytica	hypothetical protein	0.0035	0.0189	1
Schistosoma mansoni	intermediate filament proteins	0.0027	0.0089	0.0318
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0026	0.0069	0.0246
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0026	0.0069	0.0069
Schistosoma mansoni	chondroitin sulfate proteoglycan-related	0.005	0.0395	0.1416
Loa Loa (eye worm)	hypothetical protein	0.01	0.1054	0.1054
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0026	0.0069	0.0069
Echinococcus multilocularis	neutral amino acid transporter excitatory amino acid transporter	0.0054	0.0442	0.1097
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0026	0.0069	0.0346
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0026	0.0069	0.0246
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0026	0.0069	0.017
Schistosoma mansoni	sodium/dicarboxylate symporter-related	0.0054	0.0442	0.1585
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0026	0.0069	0.0069
Schistosoma mansoni	transcription factor LCR-F1	0.0035	0.0189	0.0678
Loa Loa (eye worm)	cytochrome P450 family protein	0.0023	0.0031	0.0031
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0026	0.0069	0.0069
Schistosoma mansoni	thyroid hormone receptor	0.0147	0.167	0.5985
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0026	0.0069	0.017
Echinococcus granulosus	Excitatory amino acid transporter	0.0122	0.1334	0.3313
Brugia malayi	Ets-domain containing protein	0.0077	0.0739	0.0739
Echinococcus multilocularis	Excitatory amino acid transporter	0.0122	0.1334	0.3313
Echinococcus multilocularis	GA binding protein alpha chain	0.0077	0.0739	0.1834
Schistosoma mansoni	hypothetical protein	0.0068	0.0623	0.2233
Echinococcus granulosus	Excitatory amino acid transporter	0.0122	0.1334	0.3313
Brugia malayi	nuclear hormone receptor	0.0026	0.0069	0.0069
Echinococcus granulosus	pikachurin	0.005	0.0395	0.098
Loa Loa (eye worm)	D-ets-4 DNA binding domain-containing protein	0.0077	0.0739	0.0739
Brugia malayi	Cytochrome P450 family protein	0.0023	0.0031	0.0031
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0023	0.0033	0.0081
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Echinococcus granulosus	lamin dm0	0.0027	0.0089	0.022
Echinococcus granulosus	excitatory amino acid transporter 2	0.0122	0.1334	0.3313
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0026	0.0069	0.017
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.01	0.1054	0.3777
Echinococcus granulosus	ecdysone induced protein 78C	0.0026	0.0069	0.017
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0026	0.0069	0.017
Echinococcus granulosus	Mitotic checkpoint protein PRCC C terminal	0.0122	0.1332	0.3308
Echinococcus multilocularis	slit 2 protein	0.005	0.0395	0.098
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0026	0.0069	0.017
Echinococcus multilocularis	neutral amino acid transporter excitatory amino acid transporter	0.0122	0.1334	0.3313
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0026	0.0069	0.017
Mycobacterium ulcerans	aldehyde dehydrogenase	0.012	0.1308	1
Trypanosoma cruzi	PAB1-binding protein , putative	0.0051	0.0403	0.0403
Echinococcus granulosus	voltage dependent calcium channel subunit	0.0288	0.3526	0.8752
Echinococcus multilocularis	voltage dependent calcium channel subunit	0.0131	0.1457	0.3617
Mycobacterium ulcerans	aldehyde dehydrogenase	0.012	0.1308	1
Brugia malayi	nuclear receptor NHR-88	0.0026	0.0069	0.0069
Loa Loa (eye worm)	hypothetical protein	0.005	0.0395	0.0395
Schistosoma mansoni	sodium/dicarboxylate symporter-related	0.0054	0.0442	0.1585
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0026	0.0069	0.017
Loa Loa (eye worm)	steroid hormone receptor	0.0026	0.0069	0.0069
Brugia malayi	Ets-domain containing protein	0.0077	0.0739	0.0739
Brugia malayi	hypothetical protein	0.0033	0.0165	0.0165
Brugia malayi	Kringle domain containing protein	0.0022	0.0023	0.0023
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0069	0.0069
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0026	0.0069	0.0069
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0026	0.0069	0.0069
Wolbachia endosymbiont of Brugia malayi	Na+/H+-dicarboxylate symporter	0.0122	0.1334	0.5
Schistosoma mansoni	hypothetical protein	0.0023	0.0033	0.0117
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0026	0.0069	0.017
Giardia lamblia	DINP protein human, muc B family	0.002	0	0.5
Trypanosoma brucei	PAB1-binding protein , putative	0.0051	0.0403	0.0403
Schistosoma mansoni	lamin	0.0027	0.0089	0.0318
Echinococcus multilocularis	neutral amino acid transporter A	0.0122	0.1334	0.3313
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0026	0.0069	0.0069
Schistosoma mansoni	laminin gamma-3 chain	0.005	0.0395	0.1416
Brugia malayi	Excitatory amino acid transporter	0.0122	0.1334	0.1334
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0026	0.0069	0.017
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0023	0.0033	0.0081
Trypanosoma brucei	C-8 sterol isomerase, putative	0.078	1	1
Leishmania major	hypothetical protein, conserved	0.0022	0.0023	0.0023
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0026	0.0069	0.0246
Onchocerca volvulus	Excitatory amino acid transporter homolog	0.0122	0.1334	1
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0089	0.0089
Echinococcus granulosus	intermediate filament protein	0.0027	0.0089	0.022
Treponema pallidum	methyl-accepting chemotaxis protein (mcp2-1)	0.0267	0.3245	1
Loa Loa (eye worm)	intermediate filament protein	0.0027	0.0089	0.0089
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0026	0.0069	0.0069
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0026	0.0069	0.0069
Echinococcus multilocularis	musashi	0.0027	0.0089	0.022
Brugia malayi	Cache domain containing protein	0.0058	0.0495	0.0495
Echinococcus granulosus	tumor protein p63	0.0326	0.4028	1
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.002	0	0.5
Echinococcus multilocularis	neutral amino acid transporter A	0.0122	0.1334	0.3313
Echinococcus granulosus	tissue type plasminogen activator	0.0022	0.0023	0.0058
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.078	1	1
Trichomonas vaginalis	DNA polymerase eta, putative	0.002	0	0.5
Schistosoma mansoni	cellular tumor antigen P53	0.0048	0.036	0.1292
Loa Loa (eye worm)	excitatory amino acid transporter	0.0122	0.1334	0.1334
Echinococcus multilocularis	lamin dm0	0.0027	0.0089	0.022
Chlamydia trachomatis	glutamate symporter	0.0122	0.1334	1
Loa Loa (eye worm)	abnormal epIthelia family member	0.005	0.0395	0.0395
Brugia malayi	Intermediate filament tail domain containing protein	0.0027	0.0089	0.0089
Brugia malayi	hypothetical protein	0.0035	0.0189	0.0189
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.012	0.1308	0.3247
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0026	0.0069	0.0246
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0026	0.0069	0.0069
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0026	0.0069	0.017
Echinococcus multilocularis	sodium:chloride dependent neurotransmitter	0.01	0.1054	0.2615
Brugia malayi	intermediate filament protein	0.0027	0.0089	0.0089
Schistosoma mansoni	hypothetical protein	0.0022	0.0023	0.0084
Brugia malayi	laminin alpha chain	0.005	0.0395	0.0395
Schistosoma mansoni	dihydropyridine-sensitive l-type calcium channel	0.0126	0.1387	0.4971
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0026	0.0069	0.0069
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0026	0.0069	0.0069
Echinococcus granulosus	neutral amino acid transporter A	0.0122	0.1334	0.3313
Echinococcus granulosus	slit 2 protein	0.005	0.0395	0.098
Loa Loa (eye worm)	hypothetical protein	0.0048	0.036	0.036
Schistosoma mansoni	gabp alpha	0.0077	0.0739	0.2649
Schistosoma mansoni	cell polarity protein	0.005	0.0395	0.1416
Echinococcus granulosus	sodium:dicarboxylate symporter	0.0122	0.1334	0.3313
Brugia malayi	ecdysteroid receptor	0.0026	0.0069	0.0069
Schistosoma mansoni	RAR-like nuclear receptor	0.0026	0.0069	0.0246
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0026	0.0069	0.0069
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0026	0.0069	0.017
Brugia malayi	hypothetical protein	0.0051	0.0403	0.0403
Trypanosoma cruzi	hypothetical protein, conserved	0.0022	0.0023	0.0023
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0026	0.0069	0.0069
Echinococcus multilocularis	ecdysone induced protein 78C	0.0026	0.0069	0.017
Echinococcus multilocularis	excitatory amino acid transporter 2	0.0122	0.1334	0.3313
Echinococcus multilocularis	voltage dependent calcium channel subunit	0.0288	0.3526	0.8752
Echinococcus multilocularis	excitatory amino acid transporter 3	0.0122	0.1334	0.3313
Schistosoma mansoni	lamin	0.0027	0.0089	0.0318
Schistosoma mansoni	hypothetical protein	0.0122	0.1332	0.4777

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 881529