Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0249 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | notch | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | protein jagged 2 | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Fibulin-1 precursor | 0.0249 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | protein jagged 2 | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | slit | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | Tolloid protein 1 | 0.0249 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | septate junction protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | slit 2 protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Cadherin domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | protein jagged 1 | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | notch | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | Notch2 | 0.0095 | 0.2421 | 0.2421 |
Onchocerca volvulus | 0.0095 | 0.2421 | 0.2421 | |
Onchocerca volvulus | 0.0095 | 0.2421 | 0.2421 | |
Brugia malayi | notch-like transmembrane receptor | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Onchocerca volvulus | Putative cubilin | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 1 | 1 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | protein jagged 2 | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | neural cadherin | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | neural cadherin | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Muscle positioning protein 4 | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | notch | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | EGF-like domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | cell polarity protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | notch | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | slit 2 protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | notch | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0249 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0249 | 1 | 1 |
Echinococcus multilocularis | protein jagged 1 | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | protein jagged 1 | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | notch | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | delta-like protein 1 | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | laminin | 0.0249 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | EGF-like domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | Delta serrate ligand family protein | 0.0095 | 0.2421 | 0.2421 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0095 | 0.2421 | 0.2421 |
Schistosoma mansoni | notch | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | EGF-like domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | fibropellin Ia | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | EGF-like domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0249 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0.2421 | 0.2421 | |
Echinococcus granulosus | protein jagged 1 | 0.0095 | 0.2421 | 0.2421 |
Brugia malayi | EGF-like domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | notch protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0249 | 1 | 1 |
Onchocerca volvulus | Slit protein homolog | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 1 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0249 | 1 | 1 |
Onchocerca volvulus | 0.0095 | 0.2421 | 0.2421 | |
Brugia malayi | EGF-like domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0249 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus multilocularis | fibrillin 1 | 0.0249 | 1 | 1 |
Schistosoma mansoni | egf-like domain protein | 0.0249 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 1 | 1 |
Giardia lamblia | High cysteine protein | 0.0095 | 0.2421 | 0.5 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0249 | 1 | 1 |
Echinococcus granulosus | laminin | 0.0249 | 1 | 1 |
Schistosoma mansoni | notch | 0.0095 | 0.2421 | 0.2421 |
Onchocerca volvulus | Arrow homolog | 0.0249 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0095 | 0.2421 | 0.2421 |
Onchocerca volvulus | 0.0095 | 0.2421 | 0.2421 | |
Echinococcus multilocularis | fibropellin Ia | 0.0095 | 0.2421 | 0.2421 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2421 | 0.2421 |
Mycobacterium ulcerans | hypothetical protein | 0.0046 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.