Detailed information for compound 957477

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 676.299 | Formula: C17H24N6O15P4
  • H donors: 8 H acceptors: 13 LogP: -3.56 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 4
  • SMILES: Cc1ccc(cc1)NP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N)O)O)O)O
  • InChi: 1S/C17H24N6O15P4/c1-9-2-4-10(5-3-9)22-39(26,27)36-41(30,31)38-42(32,33)37-40(28,29)34-6-11-13(24)14(25)17(35-11)23-8-21-12-15(18)19-7-20-16(12)23/h2-5,7-8,11,13-14,17,24-25H,6H2,1H3,(H,28,29)(H,30,31)(H,32,33)(H2,18,19,20)(H2,22,26,27)/t11-,13-,14-,17-/m1/s1
  • InChiKey: NBMWPRRMWQRHDU-LSCFUAHRSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Abelson murine leukemia virus Tyrosine-protein kinase V-ABL Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum expressed protein Get druggable targets OG5_131234 All targets in OG5_131234
Brugia malayi Tyrosine-protein kinase abl-1 Get druggable targets OG5_131234 All targets in OG5_131234
Schistosoma japonicum Proto-oncogene tyrosine-protein kinase ABL1, putative Get druggable targets OG5_131234 All targets in OG5_131234
Loa Loa (eye worm) TK/ABL protein kinase Get druggable targets OG5_131234 All targets in OG5_131234
Echinococcus multilocularis tyrosine protein kinase Abl Get druggable targets OG5_131234 All targets in OG5_131234
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_131234 All targets in OG5_131234
Schistosoma japonicum Tyrosine-protein kinase transforming protein Abl, putative Get druggable targets OG5_131234 All targets in OG5_131234
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131234 All targets in OG5_131234
Echinococcus granulosus tyrosine protein kinase ABL1 Get druggable targets OG5_131234 All targets in OG5_131234
Echinococcus multilocularis tyrosine protein kinase ABL1 Get druggable targets OG5_131234 All targets in OG5_131234
Schistosoma japonicum expressed protein Get druggable targets OG5_131234 All targets in OG5_131234
Schistosoma japonicum Tyrosine-protein kinase transforming protein Abl, putative Get druggable targets OG5_131234 All targets in OG5_131234
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Possible L-asparagine permease AnsP2 (L-asparagine transport protein) 0.0073 0.0713 1
Loa Loa (eye worm) hypothetical protein 0.012 0.1214 0.2257
Brugia malayi Pyruvate kinase, muscle isozyme 0.0039 0.0352 0.0654
Mycobacterium ulcerans L-asparagine permease AnsP1 0.0073 0.0713 0.956
Loa Loa (eye worm) hypothetical protein 0.044 0.4607 0.8561
Plasmodium vivax pyruvate kinase, putative 0.0039 0.0352 0.3399
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0694 0.129
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0343 0.9679
Schistosoma mansoni ferritin 0.001 0.0043 0.0081
Echinococcus multilocularis pyruvate kinase 0.0039 0.0352 0.0352
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.0343 0.8915
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0049 0.0049
Schistosoma mansoni cation chloride cotransporter 0.0073 0.0713 0.1324
Mycobacterium leprae Probable pyruvate kinase PykA 0.0039 0.0352 0.441
Brugia malayi pyruvate kinase, muscle isozyme 0.0008 0.0025 0.0047
Schistosoma mansoni tyrosine kinase 0.0313 0.3254 0.6047
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0352 0.4803
Loa Loa (eye worm) hypothetical protein 0.044 0.4607 0.8561
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Mycobacterium ulcerans pyruvate kinase 0.0039 0.0352 0.441
Toxoplasma gondii peptidylprolyl isomerase 0.0038 0.0343 0.4103
Loa Loa (eye worm) hypothetical protein 0.0031 0.0264 0.0491
Leishmania major pyruvate kinase 0.0039 0.0352 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0713 0.1324
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0466 0.6037
Echinococcus multilocularis pyruvate kinase 0.0031 0.0265 0.0265
Echinococcus multilocularis lamin 0.0031 0.027 0.027
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0743 1
Echinococcus multilocularis cation chloride cotransporter 0.0073 0.0713 0.0713
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0116 0.0216
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.027 0.0502
Mycobacterium tuberculosis Probable GABA permease GabP (4-amino butyrate transport carrier) (GAMA-aminobutyrate permease) 0.0073 0.0713 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0076 0.0743 0.1382
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0466 0.6315
Echinococcus multilocularis dnaJ subfamily B 0.0479 0.5013 0.5013
Entamoeba histolytica hypothetical protein 0.0042 0.0385 1
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0352 0.1942
Echinococcus multilocularis pyruvate kinase 0.002 0.0151 0.0151
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0385 0.0715
Loa Loa (eye worm) hypothetical protein 0.044 0.4607 0.8561
Brugia malayi Amino acid permease family protein 0.0513 0.5381 1
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0352 0.0654
Trypanosoma brucei pyruvate kinase 1 0.0039 0.0352 1
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.027 0.0502
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0098 0.0098
Echinococcus granulosus solute carrier family 12 0.0513 0.5381 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0713 0.1324
Onchocerca volvulus Solute carrier family 12 member 8 homolog 0.0073 0.0713 0.393
Brugia malayi Hypothetical 112.3 kDa protein K02A2.3 in chromosome II 0.0513 0.5381 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0466 0.0466
Trichomonas vaginalis cation chloride cotransporter, putative 0.0073 0.0713 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0038 0.0343 0.9679
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0047 0.0088
Loa Loa (eye worm) histone methyltransferase 0.001 0.0049 0.009
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0352 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.0295 0.0547
Schistosoma mansoni hypothetical protein 0.0042 0.0385 0.0715
Echinococcus granulosus pyruvate kinase 0.002 0.0151 0.028
Schistosoma mansoni ferritin 0.001 0.0043 0.0081
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0743 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0092 0.0172
Brugia malayi CXXC zinc finger family protein 0.0034 0.0295 0.0547
Loa Loa (eye worm) amino acid permease 0.0513 0.5381 1
Loa Loa (eye worm) hypothetical protein 0.044 0.4607 0.8561
Echinococcus multilocularis cpg binding protein 0.0036 0.0315 0.0315
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Echinococcus multilocularis pyruvate kinase 0.0039 0.0352 0.0352
Loa Loa (eye worm) pyruvate kinase 0.0008 0.0025 0.0047
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0216 0.1096
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0039 0.0352 0.4613
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0352 0.0654
Echinococcus granulosus cation chloride cotransporter 0.0073 0.0713 0.1324
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0385 0.0385
Echinococcus multilocularis expressed protein 0.0039 0.0353 0.0353
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0116 0.0216
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0012 0.0064 0.0297
Schistosoma mansoni intermediate filament proteins 0.0031 0.027 0.0502
Brugia malayi Tyrosine-protein kinase abl-1 0.0192 0.1978 0.3676
Schistosoma mansoni ferritin light chain 0.001 0.0043 0.0081
Schistosoma mansoni pyruvate kinase 0.0039 0.0352 0.0654
Loa Loa (eye worm) hypothetical protein 0.0513 0.5381 1
Loa Loa (eye worm) hypothetical protein 0.0513 0.5381 1
Echinococcus granulosus expressed protein 0.0039 0.0353 0.0655
Schistosoma mansoni apoferritin-2 0.001 0.0043 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Trichomonas vaginalis lysine-specific permease, putative 0.0073 0.0713 1
Schistosoma mansoni hypothetical protein 0.0479 0.5013 0.9317
Mycobacterium leprae POSSIBLE L-ASPARAGINE PERMEASE ANSP1 (L-ASPARAGINE TRANSPORT PROTEIN) 0.0073 0.0713 0.956
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0216 0.246
Loa Loa (eye worm) hypothetical protein 0.044 0.4607 0.8561
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0466 0.6315
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0216 0.246
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0012 0.0064 0.0118
Schistosoma mansoni pyruvate kinase 0.0039 0.0352 0.0654
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0743 1
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0743 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0027 0.0027
Echinococcus granulosus lamin dm0 0.0031 0.027 0.0502
Schistosoma mansoni cpg binding protein 0.0034 0.0295 0.0547
Echinococcus granulosus ferritin 0.001 0.0043 0.0081
Loa Loa (eye worm) hypothetical protein 0.044 0.4607 0.8561
Loa Loa (eye worm) hypothetical protein 0.0513 0.5381 1
Mycobacterium ulcerans GabA permease GabP 0.0073 0.0713 0.956
Echinococcus multilocularis solute carrier family 12 0.0513 0.5381 0.5381
Echinococcus granulosus pyruvate kinase 0.002 0.0151 0.028
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0027 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Brugia malayi Amino acid permease family protein 0.0073 0.0713 0.1324
Schistosoma mansoni ferritin 0.001 0.0043 0.0081
Echinococcus multilocularis expressed protein 0.001 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0092 0.0172
Echinococcus multilocularis lamin dm0 0.0031 0.027 0.027
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0039 0.0353 0.0655
Schistosoma mansoni solute carrier family 12 k-cl cotransporter 0.0073 0.0713 0.1324
Brugia malayi hypothetical protein 0.0073 0.0713 0.1324
Onchocerca volvulus 0.0031 0.027 0.1489
Loa Loa (eye worm) solute carrier family 12 member 1 0.0073 0.0713 0.1324
Onchocerca volvulus 0.0031 0.027 0.1489
Loa Loa (eye worm) hypothetical protein 0.0513 0.5381 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0049 0.009
Schistosoma mansoni lamin 0.0031 0.027 0.0502
Echinococcus multilocularis pyruvate kinase 0.002 0.0151 0.0151
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0039 0.0353 0.0655
Loa Loa (eye worm) hypothetical protein 0.0513 0.5381 1
Echinococcus granulosus pyruvate kinase 0.0039 0.0352 0.0654
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0352 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0743 1
Loa Loa (eye worm) pyruvate kinase-PB 0.0027 0.0227 0.0422
Schistosoma mansoni rotamase 0.0039 0.0353 0.0655
Echinococcus multilocularis ferritin 0.001 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0125 0.1263 0.2346
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Onchocerca volvulus Solute carrier family 12 member 9 homolog 0.0073 0.0713 0.393
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Trichomonas vaginalis gaba permease, putative 0.0073 0.0713 1
Loa Loa (eye worm) hypothetical protein 0.0513 0.5381 1
Entamoeba histolytica hypothetical protein 0.0042 0.0385 1
Trichomonas vaginalis rotamase, putative 0.0039 0.0353 0.4811
Entamoeba histolytica pyruvate kinase, putative 0.0027 0.0227 0.5899
Echinococcus granulosus expressed protein 0.001 0.0043 0.0081
Echinococcus multilocularis pyruvate kinase 0.002 0.0151 0.0151
Loa Loa (eye worm) TK/ABL protein kinase 0.0317 0.3302 0.6137
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0098 0.0183
Entamoeba histolytica hypothetical protein 0.0042 0.0385 1
Echinococcus granulosus dnaJ subfamily B 0.0479 0.5013 0.9317
Loa Loa (eye worm) hypothetical protein 0.0015 0.0098 0.0183
Brugia malayi Pyruvate kinase, M2 isozyme 0.0039 0.0352 0.0654
Brugia malayi hypothetical protein 0.0177 0.1813 0.337
Schistosoma mansoni pyruvate kinase 0.002 0.0151 0.028
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0743 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0713 0.1324
Leishmania major pyruvate kinase 0.0039 0.0352 1
Schistosoma mansoni ferritin 0.001 0.0043 0.0081
Trypanosoma brucei pyruvate kinase 1, putative 0.0039 0.0352 1
Schistosoma mansoni cpg binding protein 0.0036 0.0315 0.0585
Echinococcus multilocularis musashi 0.0031 0.027 0.027
Plasmodium falciparum pyruvate kinase 0.0039 0.0352 0.3399
Trichomonas vaginalis cation chloride cotransporter, putative 0.0073 0.0713 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0743 1
Brugia malayi solute carrier family 12 member 1 0.0073 0.0713 0.1324
Loa Loa (eye worm) hypothetical protein 0.0177 0.1813 0.337
Echinococcus granulosus cpg binding protein 0.0036 0.0315 0.0585
Trichomonas vaginalis rotamase, putative 0.0038 0.0343 0.467
Brugia malayi Probable ClpP-like protease 0.0076 0.0743 0.1382
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0352 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0352 0.4803
Echinococcus granulosus pyruvate kinase 0.002 0.0151 0.028
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0385 0.0715
Trichomonas vaginalis aromatic amino acid transporter, putative 0.0073 0.0713 1
Trichomonas vaginalis amino acid permease, putative 0.0073 0.0713 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0125 0.1263 0.1263
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0713 1
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0743 0.0743
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0352 0.1942
Schistosoma mansoni ferritin light chain 0.001 0.0043 0.0081
Mycobacterium ulcerans D-serine/D-alanine/glycine transporter, CycA 0.0073 0.0713 0.956
Trichomonas vaginalis ferritin, putative 0.001 0.0043 0.0353
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0466 0.0866
Echinococcus granulosus tyrosine protein kinase ABL1 0.0317 0.3302 0.6137
Schistosoma mansoni cpg binding protein 0.0036 0.0315 0.0585
Schistosoma mansoni solute carrier family 12 electroneutral k-cl cotransporter 0.0513 0.5381 1
Entamoeba histolytica hypothetical protein 0.0042 0.0385 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0216 0.1096
Toxoplasma gondii pyruvate kinase PyKII 0.002 0.0151 0.1273
Giardia lamblia Pyruvate kinase 0.0039 0.0352 1
Echinococcus granulosus lamin 0.0031 0.027 0.0502
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0027 0.005
Brugia malayi intermediate filament protein 0.0031 0.027 0.0502
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0743 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0227 0.0422
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0027 0.005
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0038 0.0343 0.9679
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0743 1
Loa Loa (eye worm) hypothetical protein 0.044 0.4607 0.8561
Brugia malayi hypothetical protein 0.0073 0.0713 0.1324
Brugia malayi pyruvate kinase 0.0008 0.0025 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0353 0.4811
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0743 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0317 0.3302 0.3302
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0352 0.1942
Toxoplasma gondii pyruvate kinase PyK1 0.0039 0.0352 0.4239
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0743 0.1382
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0343 0.9679
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0613 0.8085
Loa Loa (eye worm) hypothetical protein 0.0513 0.5381 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0743 0.1382
Schistosoma mansoni apoferritin-2 0.001 0.0043 0.0081
Toxoplasma gondii hypothetical protein 0.0026 0.0216 0.2229
Brugia malayi hypothetical protein 0.0042 0.0385 0.0715
Loa Loa (eye worm) hypothetical protein 0.0039 0.0352 0.0654
Echinococcus granulosus intermediate filament protein 0.0031 0.027 0.0502
Echinococcus granulosus pyruvate kinase 0.0039 0.0352 0.0654
Mycobacterium leprae POSSIBLE L-ASPARAGINE PERMEASE ANSP2 (L-ASPARAGINE TRANSPORT PROTEIN) 0.0073 0.0713 0.956
Mycobacterium tuberculosis Probable D-serine/alanine/glycine transporter protein CycA 0.0073 0.0713 1
Onchocerca volvulus 0.0177 0.1813 1
Schistosoma mansoni lamin 0.0031 0.027 0.0502
Loa Loa (eye worm) hypothetical protein 0.0031 0.027 0.0502
Onchocerca volvulus 0.0034 0.0295 0.1625
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0743 1
Loa Loa (eye worm) intermediate filament protein 0.0031 0.027 0.0502

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2 10'1 uM Inhibition of Abelson murine leukemia virus p60 v-abl ChEMBL. 1479375
IC50 (binding) = 16 uM Inhibition of p60v-abl tyrosine kinase from Abelson murine leukemia virus ChEMBL. 3045321

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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