Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.0195 | 0.0098 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0042 | 0.1062 | 0.1592 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0125 | 0.4218 | 0.8847 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0042 | 0.1062 | 0.1194 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0026 | 0.0441 | 0.1355 |
Leishmania major | trypanothione reductase | 0.0055 | 0.1552 | 0.5497 |
Brugia malayi | CAAX amino terminal protease family protein | 0.0087 | 0.2771 | 0.321 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0019 | 0.0191 | 0.0188 |
Treponema pallidum | NADH oxidase | 0.0019 | 0.0191 | 0.0041 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0055 | 0.1537 | 0.178 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0139 | 0.4748 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.1062 | 0.3688 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0195 | 0.0226 |
Echinococcus granulosus | roundabout 2 | 0.0018 | 0.0144 | 0.0209 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0278 | 1 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0784 | 0.1174 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0049 | 0.1317 | 0.2535 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0042 | 0.1062 | 0.1005 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0191 | 0.0475 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Onchocerca volvulus | 0.0275 | 0.9898 | 1 | |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0784 | 0.2963 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Onchocerca volvulus | 0.0109 | 0.3618 | 0.3615 | |
Brugia malayi | Thioredoxin reductase | 0.0055 | 0.1552 | 0.1798 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0042 | 0.1062 | 0.1005 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0055 | 0.1552 | 0.1764 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0195 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0144 | 0.0127 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.1552 | 0.5497 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0055 | 0.1537 | 0.3014 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0055 | 0.1537 | 0.3105 |
Trichomonas vaginalis | set domain proteins, putative | 0.0275 | 0.9898 | 0.9897 |
Entamoeba histolytica | CAAX prenyl protease family | 0.0087 | 0.2771 | 0.2726 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0136 | 0.4614 | 0.9688 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0042 | 0.1062 | 0.1005 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0242 | 0.8632 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0055 | 0.1552 | 0.6556 |
Schistosoma mansoni | alpha-glucosidase | 0.0163 | 0.5644 | 0.9238 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0042 | 0.1062 | 0.1005 |
Brugia malayi | glutathione reductase | 0.0055 | 0.1552 | 0.1798 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.0195 | 0.0186 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.0195 | 0.0488 |
Trypanosoma cruzi | peptidase with unknown catalytic mechanism (family U48) | 0.0087 | 0.2771 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.1062 | 0.1005 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0026 | 0.0441 | 0.1355 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0019 | 0.0191 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.2288 | 0.262 |
Onchocerca volvulus | 0.0035 | 0.0784 | 0.0733 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0784 | 0.2963 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0074 | 0.2288 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.0736 | 0.1102 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0049 | 0.1317 | 0.2535 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0191 | 0.0475 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0055 | 0.1552 | 0.2331 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0019 | 0.0191 | 0.0306 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0019 | 0.0191 | 0.0129 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0125 | 0.4218 | 0.8847 |
Echinococcus granulosus | CAAX prenyl protease 2 | 0.0087 | 0.2771 | 0.4168 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0042 | 0.1062 | 0.1005 |
Brugia malayi | Pre-SET motif family protein | 0.0242 | 0.8632 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0784 | 0.1277 |
Entamoeba histolytica | CAAX amino terminal protease family | 0.0018 | 0.0151 | 0.0089 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0042 | 0.1062 | 0.1005 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0139 | 0.4748 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0019 | 0.0191 | 0.0188 |
Trichomonas vaginalis | Clan U, family U48, CaaX prenyl peptidase 2-like | 0.0087 | 0.2771 | 0.2726 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0019 | 0.0191 | 0.0281 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0074 | 0.2288 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0019 | 0.0191 | 0.0188 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0136 | 0.4614 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0055 | 0.1552 | 0.1764 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0784 | 0.0909 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.1062 | 0.1005 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 1 |
Leishmania major | CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) | 0.0087 | 0.2771 | 1 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0087 | 0.2771 | 0.4533 |
Entamoeba histolytica | CAAX amino terminal protease family | 0.0018 | 0.0151 | 0.0089 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0189 | 0.6643 | 0.7695 |
Plasmodium vivax | glutathione reductase, putative | 0.0055 | 0.1552 | 0.6556 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0015 | 0.0035 | 0.0045 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0055 | 0.1537 | 0.251 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0278 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Echinococcus multilocularis | CAAX prenyl protease 2 | 0.0087 | 0.2771 | 0.4168 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0019 | 0.0191 | 0.0281 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0049 | 0.1317 | 0.1977 |
Plasmodium falciparum | glutathione reductase | 0.0055 | 0.1552 | 0.6556 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0055 | 0.1537 | 0.3105 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0019 | 0.0191 | 0.0475 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0019 | 0.0191 | 0.009 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0074 | 0.2288 | 0.4287 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0125 | 0.4218 | 0.8847 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0026 | 0.0441 | 0.0294 |
Trypanosoma cruzi | CAAX prenyl protease 2, putative | 0.0087 | 0.2771 | 1 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0019 | 0.0191 | 0.0129 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0125 | 0.4218 | 0.8847 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0074 | 0.2288 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0183 | 0.6391 | 0.7403 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0183 | 0.6391 | 0.7393 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0441 | 0.1355 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.009 | 0.2865 | 0.4686 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 0.2169 |
Onchocerca volvulus | 0.009 | 0.2865 | 0.2849 | |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0171 | 0.5935 | 0.597 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 0.3439 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0195 | 0.0488 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2865 | 0.3292 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0189 | 0.6643 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0019 | 0.0191 | 0.0475 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0042 | 0.1062 | 0.1592 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 0.4787 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 1 |
Onchocerca volvulus | 0.0084 | 0.2644 | 0.2624 | |
Giardia lamblia | Hypothetical protein | 0.0087 | 0.2771 | 0.263 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0784 | 0.0872 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0042 | 0.1062 | 0.4261 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0019 | 0.0191 | 0.0188 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0195 | 0.0186 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0784 | 0.1174 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0049 | 0.1317 | 0.2034 |
Trypanosoma brucei | glucosidase, putative | 0.0042 | 0.1062 | 0.3688 |
Mycobacterium tuberculosis | Probable reductase | 0.0125 | 0.4218 | 0.8847 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 0.4787 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0042 | 0.1062 | 0.123 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0019 | 0.0191 | 0.0188 |
Schistosoma mansoni | cell adhesion molecule | 0.0015 | 0.0035 | 0.0049 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0784 | 0.1174 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.009 | 0.2865 | 0.4686 |
Toxoplasma gondii | thioredoxin reductase | 0.0055 | 0.1552 | 0.6556 |
Brugia malayi | Probable ClpP-like protease | 0.0074 | 0.2288 | 0.265 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0144 | 0.0127 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.1062 | 0.3688 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.1062 | 0.1005 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0019 | 0.0191 | 0.0475 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0139 | 0.4748 | 1 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0055 | 0.1537 | 0.5442 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0019 | 0.0191 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.2771 | 0.3183 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0191 | 0.0475 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0136 | 0.4614 | 0.9708 |
Plasmodium falciparum | thioredoxin reductase | 0.0055 | 0.1552 | 0.6556 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0055 | 0.1552 | 0.5497 |
Onchocerca volvulus | 0.0167 | 0.5787 | 0.582 | |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0125 | 0.4218 | 0.877 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.2865 | 0.3292 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0125 | 0.4218 | 0.8847 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.009 | 0.2865 | 0.3319 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0055 | 0.1552 | 0.3046 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0195 | 0.0488 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0051 | 0.1398 | 0.1585 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0074 | 0.2288 | 0.3439 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0784 | 0.1277 |
Schistosoma mansoni | alpha glucosidase | 0.0042 | 0.1062 | 0.1732 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0049 | 0.1317 | 0.1977 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0191 | 0.0222 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0189 | 0.6643 | 0.7686 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0074 | 0.2288 | 0.374 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0019 | 0.0191 | 0.009 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.1062 | 0.1005 |
Trypanosoma brucei | cytochrome P450, putative | 0.0019 | 0.0195 | 0.0488 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0063 | 0.0033 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0042 | 0.1062 | 0.1005 |
Plasmodium falciparum | thioredoxin reductase | 0.0019 | 0.0191 | 0.0188 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0042 | 0.1062 | 0.3688 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0019 | 0.0191 | 0.0188 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0087 | 0.2771 | 0.4533 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0019 | 0.0191 | 0.0087 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0195 | 0.0226 |
Schistosoma mansoni | alpha-glucosidase | 0.0163 | 0.5644 | 0.9238 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0019 | 0.0191 | 0.0475 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0055 | 0.1537 | 0.2308 |
Echinococcus multilocularis | roundabout 2 | 0.0018 | 0.0144 | 0.0209 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0016 | 0.0063 | 0.0073 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0784 | 0.1277 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0139 | 0.4748 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0278 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0189 | 0.6643 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0019 | 0.0191 | 0.009 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0055 | 0.1537 | 0.2308 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0019 | 0.0191 | 0.0188 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0189 | 0.6643 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0055 | 0.1552 | 0.2331 |
Trypanosoma brucei | CAAX amino terminal protease, putative | 0.0087 | 0.2771 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0784 | 0.1277 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.