Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | acyl-CoA desaturase | 0.16 | 0.905 | 1 |
Leishmania major | fatty-acid desaturase, putative | 0.1762 | 1 | 1 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.16 | 0.905 | 0.5 |
Onchocerca volvulus | 0.1762 | 1 | 1 | |
Echinococcus granulosus | Fatty acid desaturase type 1 | 0.0162 | 0.0602 | 0.5 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3 | 0.0162 | 0.0602 | 0.5 |
Mycobacterium ulcerans | electron transfer protein FdxB | 0.0162 | 0.0602 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0162 | 0.0602 | 0.5 |
Brugia malayi | acyl-CoA desaturase | 0.16 | 0.905 | 1 |
Echinococcus multilocularis | Peptidase M, neutral zinc metallopeptidases, zinc binding site | 0.0162 | 0.0602 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.16 | 0.905 | 0.8989 |
Mycobacterium ulcerans | transmembrane alkane 1-monooxygenase AlkB | 0.0162 | 0.0602 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.1762 | 1 | 1 |
Brugia malayi | Fatty acid desaturase family protein | 0.0162 | 0.0602 | 0.0665 |
Mycobacterium tuberculosis | Probable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauric acid omega-hydroxylase) (omega-hydroxylase) (f | 0.0162 | 0.0602 | 0.5 |
Mycobacterium tuberculosis | Probable conserved membrane protein | 0.0162 | 0.0602 | 0.5 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.1762 | 1 | 1 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3 | 0.0162 | 0.0602 | 0.5 |
Loa Loa (eye worm) | fatty acid desaturase | 0.0162 | 0.0602 | 0.0665 |
Echinococcus multilocularis | Fatty acid desaturase, type 1 | 0.0162 | 0.0602 | 0.5 |
Onchocerca volvulus | 0.1762 | 1 | 1 | |
Echinococcus granulosus | Sphingolipid delta4 desaturase DES1 | 0.0162 | 0.0602 | 0.5 |
Mycobacterium tuberculosis | Possible electron transfer protein FdxB | 0.0162 | 0.0602 | 0.5 |
Echinococcus multilocularis | Peptidase M, neutral zinc metallopeptidases, zinc binding site | 0.0162 | 0.0602 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.16 | 0.905 | 0.8989 |
Schistosoma mansoni | fatty acid desaturase | 0.0162 | 0.0602 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0162 | 0.0602 | 0.5 |
Toxoplasma gondii | sphingolipid delta 4 desaturase/c-4 hydroxylase protein des2 family protein | 0.0162 | 0.0602 | 0.5 |
Brugia malayi | Fatty acid desaturase family protein | 0.0162 | 0.0602 | 0.0665 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.16 | 0.905 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0602 | 0.0665 |
Mycobacterium ulcerans | linoleoyl-CoA desaturase, DesA3_2 | 0.0162 | 0.0602 | 0.5 |
Loa Loa (eye worm) | FAT-3 protein | 0.0162 | 0.0602 | 0.0665 |
Brugia malayi | Delta5 fatty acid desaturase | 0.0162 | 0.0602 | 0.0665 |
Loa Loa (eye worm) | fatty acid desaturase | 0.0162 | 0.0602 | 0.0665 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.