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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
4804 records found | Showing page 3 of 193 (records 51-75) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
P. falciparum | PF3D7_0922600 | OG5_127086 | glutamine synthetase, putative | 353 |
P. falciparum | PF3D7_1331100 | OG5_153054 | DNA polymerase theta, putative | 351 |
P. falciparum | PF3D7_0206000 | OG5_128675 | DNA repair protein RAD2, putative | 351 |
P. falciparum | PF3D7_1407900 | OG5_126885 | plasmepsin I | 348 |
P. falciparum | PF3D7_1120100 | OG5_127491 | phosphoglycerate mutase, putative | 346 |
P. falciparum | PF3D7_1438900 | OG5_126593 | thioredoxin peroxidase 1 | 346 |
P. falciparum | PF3D7_0624000 | OG5_126743 | hexokinase | 345 |
P. falciparum | PF3D7_0907900 | OG5_128237 | peptide deformylase | 345 |
P. falciparum | PF3D7_1219900 | OG5_127027 | ribulose-phosphate 3-epimerase, putative | 345 |
P. falciparum | PF3D7_1129000 | OG5_127074 | spermidine synthase | 344 |
P. falciparum | PF3D7_0209300 | OG5_130616 | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 342 |
P. falciparum | PF3D7_0215700 | OG5_126694 | DNA-directed RNA polymerase II subunit RPB2, putative | 342 |
P. falciparum | PF3D7_1216200 | OG5_126704 | glycerol-3-phosphate dehydrogenase, putative | 342 |
P. falciparum | PF3D7_1115300 | OG5_126607 | cysteine proteinase falcipain 2b | 341 |
P. falciparum | PF3D7_1116700 | OG5_130494 | dipeptidyl aminopeptidase 1 | 341 |
P. falciparum | PF3D7_1453800 | OG5_127121 | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 341 |
P. falciparum | PF3D7_0422000 | OG5_126812 | steroid dehydrogenase, putative | 341 |
P. falciparum | PF3D7_1408000 | OG5_126885 | plasmepsin II | 340 |
P. falciparum | PF3D7_1308200 | OG5_126835 | carbamoyl phosphate synthetase | 339 |
P. falciparum | PF3D7_1329400 | OG5_126856 | AMP deaminase, putative | 337 |
P. falciparum | PF3D7_1215000 | OG5_126593 | thioredoxin peroxidase 2 | 337 |
P. falciparum | PF3D7_0922200 | OG5_126734 | S-adenosylmethionine synthetase | 336 |
P. falciparum | PF3D7_1212800 | OG5_126893 | iron-sulfur subunit of succinate dehydrogenase | 335 |
P. falciparum | PF3D7_0814900 | OG5_126676 | superoxide dismutase [Fe] | 333 |
P. falciparum | PF3D7_1015900 | OG5_126698 | enolase | 331 |