Target list

Search results for query: Pfal rankings for 19 criteria -- reweightable!

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #303 (Pfal PDB structures): 50
  • Score for genes in query #313 (Pfal less than 100 kDa): 20
  • Score for genes in query #302 (Pfal structural models): 30
  • Score for genes in query #310 (Pfal late trophozoite 80-100): 8
  • Score for genes in query #316 (Pfal early schizont 60-80): 4
  • Score for genes in query #295 (Pfal early trophozoite 80-100): 8
  • Score for genes in query #291 (Pfal assayable): 30
  • Score for genes in query #315 (Pfal compound desirability > 0.3): 35
  • Score for genes in query #311 (Pfal druggability > 0.6): 35
  • Score for genes in query #292 (Pfal merozoite 80-100): 8
  • Score for genes in query #307 (Pfal genetic validation): 50
  • Score for genes in query #294 (Pfal early schizont 80-100): 8
  • Score for genes in query #309 (Pfal no TM domains): 20
  • Score for genes in query #305 (Pfal not in humans): 25
  • Score for genes in query #298 (Pfal late schizont 80-100): 8
  • Score for genes in query #299 (Pfal essential in at least one organism): 40
  • Score for genes in query #300 (Pfal publications): 35
  • Score for genes in query #296 (Pfal early ring 60-80): 4
  • Score for genes in query #314 (Pfal late ring 60-80): 4
  • Score for genes in query #312 (Pfal merozoite 60-80): 4
  • Score for genes in query #301 (Pfal enzymes): 100
  • Score for genes in query #304 (Pfal late trophozoite 60-80): 4
  • Score for genes in query #297 (Pfal early ring 80-100): 8
  • Score for genes in query #308 (Pfal early trophozoite 60-80): 4
  • Score for genes in query #306 (Pfal late ring 80-100): 8
  • Score for genes in query #293 (Pfal late schizont 60-80): 4

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 3 of 193 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0922600   OG5_127086   glutamine synthetase, putative 353
P. falciparum   PF3D7_1331100   OG5_153054   DNA polymerase theta, putative 351
P. falciparum   PF3D7_0206000   OG5_128675   DNA repair protein RAD2, putative 351
P. falciparum   PF3D7_1407900   OG5_126885   plasmepsin I 348
P. falciparum   PF3D7_1120100   OG5_127491   phosphoglycerate mutase, putative 346
P. falciparum   PF3D7_1438900   OG5_126593   thioredoxin peroxidase 1 346
P. falciparum   PF3D7_0624000   OG5_126743   hexokinase 345
P. falciparum   PF3D7_0907900   OG5_128237   peptide deformylase 345
P. falciparum   PF3D7_1219900   OG5_127027   ribulose-phosphate 3-epimerase, putative 345
P. falciparum   PF3D7_1129000   OG5_127074   spermidine synthase 344
P. falciparum   PF3D7_0209300   OG5_130616   2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 342
P. falciparum   PF3D7_0215700   OG5_126694   DNA-directed RNA polymerase II subunit RPB2, putative 342
P. falciparum   PF3D7_1216200   OG5_126704   glycerol-3-phosphate dehydrogenase, putative 342
P. falciparum   PF3D7_1115300   OG5_126607   cysteine proteinase falcipain 2b 341
P. falciparum   PF3D7_1116700   OG5_130494   dipeptidyl aminopeptidase 1 341
P. falciparum   PF3D7_1453800   OG5_127121   glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 341
P. falciparum   PF3D7_0422000   OG5_126812   steroid dehydrogenase, putative 341
P. falciparum   PF3D7_1408000   OG5_126885   plasmepsin II 340
P. falciparum   PF3D7_1308200   OG5_126835   carbamoyl phosphate synthetase 339
P. falciparum   PF3D7_1329400   OG5_126856   AMP deaminase, putative 337
P. falciparum   PF3D7_1215000   OG5_126593   thioredoxin peroxidase 2 337
P. falciparum   PF3D7_0922200   OG5_126734   S-adenosylmethionine synthetase 336
P. falciparum   PF3D7_1212800   OG5_126893   iron-sulfur subunit of succinate dehydrogenase 335
P. falciparum   PF3D7_0814900   OG5_126676   superoxide dismutase [Fe] 333
P. falciparum   PF3D7_1015900   OG5_126698   enolase 331

Showing page 3 (records 51-75) of 193