Target list

Search results for query: Union of (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 24)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #11 (TM): -3
  • Score for genes in query #15 (EC ): 3
  • Score for genes in query #5 (Trypanosomatids): 7
  • Score for genes in query #24 (PiNoDrug4 WARNING: we were unable to find some of the genes in your list!): weighted list
  • Score for genes in query #14 (Signal Peptide): -3
  • Score for genes in query #12 (Paralogos): -3
  • Score for genes in query #8 (Assayability - Soluble): 5
  • Score for genes in query #13 (GPI): -3
  • Score for genes in query #4 (Essential (-C. elegans)): 23
  • Score for genes in query #10 (PM 100kDa): 3
  • Score for genes in query #6 (Not In Mammals): 11
  • Score for genes in query #9 (Pubmed): 7
  • Score for genes in query #7 (Assayability - Assay Available): 5

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

18566 records found | Showing page 3 of 743 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.511229.110   OG5_127272   glycyl-tRNA synthetase, putative 1126
T. cruzi   TcCLB.506297.240   OG5_127102   protein transport protein SEC61 subunit alpha, putative 1125
T. cruzi   TcCLB.504797.100   OG5_133785   rotamase, putative 1125
T. cruzi   TcCLB.511577.40   OG5_133785   35 kDa cyclophilin, putative 1125
T. cruzi   TcCLB.510101.70   OG5_127102   pretranslocation protein, alpha subunit, putative 1125
T. cruzi   TcCLB.508319.40   OG5_127438   ATP-dependent RNA helicase SUB2, putative 1125
T. cruzi   TcCLB.503589.10   OG5_127109   GDP-mannose pyrophosphorylase 1125
T. cruzi   TcCLB.510947.10   OG5_127109   GDP-mannose pyrophosphorylase 1125
T. cruzi   TcCLB.506303.50   OG5_126853   UDP-galactose 4-epimerase, putative 1124
T. cruzi   TcCLB.507811.30   OG5_127962   ATP-dependent DEAD/H RNA helicase, putative 1124
T. cruzi   TcCLB.506811.190   OG5_126853   UDP-galactose 4-epimerase 1124
T. cruzi   TcCLB.506625.110   OG5_145769   DNA topoisomerase type IB small subunit, putative 1124
T. cruzi   TcCLB.507603.200   OG5_127831   proteasome regulatory ATPase subunit 3, putative 1123
T. cruzi   TcCLB.509429.270   OG5_127831   proteasome regulatory ATPase subunit 3, putative 1123
T. cruzi   TcCLB.506213.120   OG5_126849   ATP-dependent RNA helicase HEL67 1123
T. cruzi   TcCLB.511211.20   OG5_127608   Coatomer subunit gamma 1123
T. cruzi   TcCLB.511285.120   OG5_126849   ATP-dependent RNA helicase HEL67 1123
T. cruzi   TcCLB.511649.150   OG5_129378   phosphoglycerate mutase protein, putative 1122
T. cruzi   TcCLB.510141.10   OG5_126909   thymine-7-hydroxylase, putative 1122
T. cruzi   TcCLB.507241.30   OG5_128330   arginine kinase 1122
T. cruzi   TcCLB.510531.54   OG5_127814   small nuclear ribonucleoprotein, putative 1122
T. cruzi   TcCLB.511819.14   OG5_127814   small nuclear ribonucleoprotein, putative 1122
T. cruzi   TcCLB.510889.221   OG5_126980   glucose-6-phosphate isomerase, glycosomal, putative 1122
T. cruzi   TcCLB.510285.60   OG5_127211   ubiquinone biosynthesis methyltransferase, putative 1121
T. cruzi   TcCLB.507027.59   OG5_127602   pre-mRNA cleavage complex II Clp1 protein, putative 1121

Showing page 3 (records 51-75) of 743