Target list

Search results for query: PLoS NTD Query 7 (P. falciparum apicoplast)

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  • Score for genes in query #236 (Pfa any essentiality): 50
  • Score for genes in query #242 (Pfa Pubmed): -20
  • Score for genes in query #235 (Pfa Enzymes (EC + functional category)): 100
  • Score for genes in query #237 (Pfa all proteins): 1
  • Score for genes in query #246 (Pfa ortholog in taxon (Pvi)): 50
  • Score for genes in query #251 (Curated list of nuclear encode apicoplast targeted gene from Stuart Ralph): 1000
  • Score for genes in query #249 (Pfa assayable): 20
  • Score for genes in query #241 (Pfa compound desirability >0.2): 10
  • Score for genes in query #244 (Pfa Modbase structure models): 10
  • Score for genes in query #248 (Pfa Dindex >=0.4): 20
  • Score for genes in query #239 (Pfa uploaded weighted list for Isoelectric point): 0
  • Score for genes in query #247 (Pfa any genetic validation): -50
  • Score for genes in query #245 (Pfa NOT in humans): 50
  • Score for genes in query #238 (Pfa expression in any RBC stage (80-100%)): 25
  • Score for genes in query #240 (Pfa uploaded weighted list for molecular weight): 0
  • Score for genes in query #243 (Pfa PDB structures): -100

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 3 of 193 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1033800   OG5_145118   plasmepsin VII 1191
P. falciparum   PF3D7_1312000   OG5_127857   malonyl CoA-acyl carrier protein transacylase 1191
P. falciparum   PF3D7_1318200   OG5_137532   glycerol-3-phosphate 1-O-acyltransferase 1191
P. falciparum   PF3D7_1323500   OG5_132039   plasmepsin V 1191
P. falciparum   PF3D7_0203900   OG5_132022   5'-3' exonuclease, N-terminal resolvase-like domain, putative 1191
P. falciparum   PF3D7_0311200   OG5_167026   valine--tRNA ligase, putative 1191
P. falciparum   PF3D7_0615100   OG5_130466   enoyl-acyl carrier reductase 1191
P. falciparum   PF3D7_1201600   OG5_173806   NIMA related kinase 3 1191
P. falciparum   PF3D7_1209600   OG5_127395   porphobilinogen deaminase 1191
P. falciparum   PF3D7_1239500   OG5_128755   DNA gyrase subunit B 1191
P. falciparum   PF3D7_0206100   OG5_127283   cysteine desulfuration protein SufE 1186
P. falciparum   PF3D7_0918000   OG5_129627   glideosome-associated protein 50 1186
P. falciparum   PF3D7_1350700   OG5_130478   N6-adenine-specific methylase, putative 1161
P. falciparum   PF3D7_1364600   OG5_126648   aldehyde reductase, putative 1161
P. falciparum   PF3D7_1018000   OG5_126700   tRNA pseudouridine synthase, putative 1161
P. falciparum   PF3D7_1103400   OG5_132298   FeS cluster assembly protein SufD, putative 1161
P. falciparum   PF3D7_1413500   OG5_130065   FeS assembly ATPase SufC 1161
P. falciparum   PF3D7_1429100   OG5_127198   apicoplast ribosomal protein L15 precursor, putative 1161
P. falciparum   PF3D7_1431800   OG5_133039   apyrase, putative 1161
P. falciparum   PF3D7_1469000   OG5_130791   translation initiation factor IF-1 1161
P. falciparum   PF3D7_0209300   OG5_130616   2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1161
P. falciparum   PF3D7_0613400   OG5_130467   apicoplast ribosomal protein L18 precursor, putative 1161
P. falciparum   PF3D7_0623500   OG5_158563   superoxide dismutase [Fe] 1161
P. falciparum   PF3D7_0930500   OG5_155356   diacylglycerol kinase, putative 1161
P. falciparum   PF3D7_0307400   OG5_127187   ATP-dependent Clp protease proteolytic subunit 1156

Showing page 3 (records 51-75) of 193