Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2250 records found | Showing page 3 of 90 (records 51-75) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0902c | OG5_127115 | Two component sensor histidine kinase PrrB | 150 |
M. tuberculosis | Rv1311 | OG5_127404 | Probable ATP synthase epsilon chain AtpC | 145 |
M. tuberculosis | Rv1092c | OG5_141174 | Probable pantothenate kinase CoaA (pantothenic acid kinase) | 145 |
M. tuberculosis | Rv1631 | OG5_127254 | Probable dephospho-CoA kinase CoaE (dephosphocoenzyme a kinase) | 145 |
M. tuberculosis | Rv0429c | OG5_128237 | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 145 |
M. tuberculosis | Rv2447c | OG5_126889 | Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate syn ... | 145 |
M. tuberculosis | Rv3609c | OG5_127507 | GTP cyclohydrolase I FolE (GTP-ch-I) | 145 |
M. tuberculosis | Rv0989c | No group | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthet ... | 145 |
M. tuberculosis | Rv1300 | OG5_128078 | Probable HemK protein homolog HemK | 145 |
M. tuberculosis | Rv1485 | OG5_127510 | Ferrochelatase HemZ (protoheme ferro-lyase) (heme synthetase) | 145 |
M. tuberculosis | Rv2121c | OG5_129102 | ATP phosphoribosyltransferase HisG | 145 |
M. tuberculosis | Rv1437 | OG5_126776 | Probable phosphoglycerate kinase Pgk | 145 |
M. tuberculosis | Rv1822 | OG5_127373 | Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA ... | 145 |
M. tuberculosis | Rv2746c | OG5_127373 | Probable PGP synthase PgsA3 (CDP-diacylglycerol--glycerol-3-phosphate 3- phospha ... | 145 |
M. tuberculosis | Rv1649 | OG5_127036 | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 145 |
M. tuberculosis | Rv0500 | OG5_126801 | Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) | 145 |
M. tuberculosis | Rv2182c | OG5_126904 | 1-acylglycerol-3-phosphate O-acyltransferase | 145 |
M. tuberculosis | Rv3336c | OG5_127531 | Probable tryptophanyl-tRNA synthetase TrpS (tryptophan--tRNA ligase) (TRPRS) (tr ... | 145 |
M. tuberculosis | Rv3913 | OG5_127532 | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 145 |
M. tuberculosis | Rv1689 | OG5_127413 | Probable tyrosyl-tRNA synthase TyrS (TYRRS) | 145 |
M. tuberculosis | Rv1568 | OG5_128068 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 140 |
M. tuberculosis | Rv2882c | OG5_127647 | Ribosome recycling factor Frr (ribosome releasing factor) (RRF) | 140 |
M. tuberculosis | Rv0440 | OG5_126788 | 60 kDa chaperonin 2 GroEL2 (protein CPN60-2) (GroEL protein 2) (65 kDa antigen) ... | 140 |
M. tuberculosis | Rv2861c | OG5_126721 | Methionine aminopeptidase MapB (map) (peptidase M) | 140 |
M. tuberculosis | Rv3566c | OG5_131280 | Arylamine N-acetyltransferase Nat (arylamine acetylase) | 140 |