Detailed information for compound 1022969

Basic information

Technical information
  • TDR Targets ID: 1022969
  • Name: [5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-ox o-7-sulfooxychromen-3-yl] hydrogen sulfate
  • MW: 476.389 | Formula: C16H12O13S2
  • H donors: 4 H acceptors: 9 LogP: 1.3 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1O)c1oc2cc(cc(c2c(=O)c1OS(=O)(=O)O)O)OS(=O)(=O)O
  • InChi: 1S/C16H12O13S2/c1-26-11-4-7(2-3-9(11)17)15-16(29-31(23,24)25)14(19)13-10(18)5-8(6-12(13)27-15)28-30(20,21)22/h2-6,17-18H,1H3,(H,20,21,22)(H,23,24,25)
  • InChiKey: ROYNQIRDSFCDQL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • [5-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-4-oxo-7-sulfooxy-chromen-3-yl] hydrogen sulfate
  • [5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-7-sulfooxy-3-chromenyl] hydrogen sulfate
  • [5-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-4-keto-7-sulfoxy-chromen-3-yl] hydrogen sulfate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Conserved hypothetical protein 0.0077 0.0625 0.1778
Loa Loa (eye worm) hypothetical protein 0.0052 0.0347 0.1259
Loa Loa (eye worm) hypothetical protein 0.0049 0.0311 0.1128
Echinococcus multilocularis integrin alpha ps 0.0026 0.0061 0.0043
Schistosoma mansoni hypothetical protein 0.0047 0.029 0.1601
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0088 1
Schistosoma mansoni tar DNA-binding protein 0.006 0.0432 0.2437
Mycobacterium ulcerans putative transglutaminase-like protein 0.0077 0.0625 0.1778
Brugia malayi calpain family protein 1 0.0074 0.0589 0.2082
Schistosoma mansoni hypothetical protein 0.0032 0.0126 0.0635
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0154 0.0337
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.1018 0.2488
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0309 0.0292
Echinococcus granulosus integrin beta 2 0.0183 0.1784 0.4395
Echinococcus granulosus integrin alpha 3 0.0092 0.0791 0.1923
Onchocerca volvulus 0.0057 0.04 0.5905
Schistosoma mansoni tar DNA-binding protein 0.006 0.0432 0.2437
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0088 0.5
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0076 0.0215
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0126 0.0394
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase 0.013 0.1199 1
Schistosoma mansoni hypothetical protein 0.0041 0.023 0.1248
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0756 0.0739
Schistosoma mansoni hypothetical protein 0.0032 0.0126 0.0635
Giardia lamblia Hypothetical protein 0.0077 0.0625 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0077 0.0625 0.1778
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0046 0.0163
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0076 0.0573
Loa Loa (eye worm) calpain 5 0.0022 0.0018 0.0066
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.023 0.0527
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0115 0.1037 0.6001
Echinococcus multilocularis tar DNA binding protein 0.006 0.0432 0.0414
Schistosoma mansoni patched 1 0.0049 0.0309 0.1714
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0798 0.1939
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0076 0.0573
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0756 0.1835
Echinococcus multilocularis Transglutaminase 0.0077 0.0625 0.0608
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0076 0.0215
Trypanosoma cruzi kinesin, putative 0.0022 0.0018 0.5
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0274
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.006 0.0432 0.1567
Trypanosoma brucei kinesin, putative 0.0022 0.0018 0.5
Schistosoma mansoni hypothetical protein 0.0177 0.1716 1
Echinococcus multilocularis survival motor neuron protein 1 0.0272 0.2758 0.2745
Loa Loa (eye worm) TAR-binding protein 0.006 0.0432 0.1567
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0076 0.0215
Loa Loa (eye worm) calpain 0.0022 0.0018 0.0066
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0018 0.5
Brugia malayi hypothetical protein 0.0041 0.023 0.0774
Loa Loa (eye worm) hypothetical protein 0.0091 0.0777 0.2819
Brugia malayi Bromodomain containing protein 0.0028 0.0088 0.0256
Schistosoma mansoni tar DNA-binding protein 0.006 0.0432 0.2437
Trichomonas vaginalis peptide N-glycanase, putative 0.0077 0.0625 1
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.023 0.1248
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0154 0.0799
Brugia malayi calpain family protein 1 0.0074 0.0589 0.2082
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0088 0.5
Giardia lamblia Transglutaminase/protease, putative 0.0077 0.0625 1
Echinococcus multilocularis expressed conserved protein 0.0106 0.0943 0.0926
Schistosoma mansoni hypothetical protein 0.0047 0.029 0.1601
Entamoeba histolytica hypothetical protein 0.0041 0.023 0.212
Brugia malayi Niemann-Pick C1 protein precursor 0.0113 0.1018 0.3649
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.023 0.0212
Echinococcus granulosus tar DNA binding protein 0.006 0.0432 0.103
Echinococcus granulosus integrin alpha ps 0.0054 0.037 0.0875
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0756 0.0739
Brugia malayi Thioredoxin family protein 0.0077 0.0625 0.2216
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0076 0.0215
Echinococcus multilocularis muscleblind protein 1 0.0141 0.1322 0.1306
Mycobacterium ulcerans hypothetical protein 0.0077 0.0625 0.1778
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0126 0.0268
Entamoeba histolytica hypothetical protein 0.0041 0.023 0.212
Loa Loa (eye worm) hypothetical protein 0.0057 0.04 0.1451
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0076 0.0573
Echinococcus multilocularis peregrin 0.0028 0.0088 0.007
Schistosoma mansoni tar DNA-binding protein 0.006 0.0432 0.2437
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0309 0.1122
Brugia malayi Integrin beta pat-3 precursor 0.0247 0.2487 0.901
Schistosoma mansoni survival motor neuron protein 0.0055 0.0385 0.2159
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0038 0.0188 0.0683
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0018 0.5
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.032
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0018 0.5
Echinococcus multilocularis GPCR, family 2 0.0032 0.0126 0.0108
Loa Loa (eye worm) integrin alpha pat-2 0.0186 0.1816 0.6585
Loa Loa (eye worm) calpain family protein 1 0.0052 0.0347 0.1259
Schistosoma mansoni hypothetical protein 0.0032 0.0126 0.0635
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0881 0.3195
Loa Loa (eye worm) hypothetical protein 0.0069 0.0532 0.1928
Loa Loa (eye worm) hypothetical protein 0.0059 0.0429 0.1556
Mycobacterium tuberculosis Hypothetical protein 0.0077 0.0625 0.1778
Mycobacterium tuberculosis Conserved protein 0.0077 0.0625 0.1778
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0076 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0126 0.0457
Loa Loa (eye worm) integrin beta-2 0.0247 0.2487 0.9016
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0074 0.0589 0.3361
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0588 0.3354
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0756 0.274
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.042 0.1524
Brugia malayi Integrin alpha pat-2 precursor 0.0121 0.11 0.3947
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0076 0.0215
Echinococcus granulosus muscleblind protein 0.0141 0.1322 0.3245
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0532 0.1874
Echinococcus multilocularis integrin beta 2 0.0183 0.1784 0.1769
Loa Loa (eye worm) hypothetical protein 0.0052 0.0347 0.1259
Brugia malayi RNA recognition motif domain containing protein 0.006 0.0432 0.151
Mycobacterium ulcerans transglutaminase family protein 0.0077 0.0625 0.1778
Entamoeba histolytica hypothetical protein 0.0041 0.023 0.212
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0088 0.0412
Onchocerca volvulus Alhambra homolog 0.0028 0.0088 0.0233
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0076 0.0215
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0756 0.1835
Entamoeba histolytica hypothetical protein 0.0041 0.023 0.212
Schistosoma mansoni tar DNA-binding protein 0.006 0.0432 0.2437
Brugia malayi PHD-finger family protein 0.0028 0.0088 0.0256
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0076 0.0209
Schistosoma mansoni integrin alpha-ps 0.0028 0.0085 0.0396
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0018 0.5
Brugia malayi jmjC domain containing protein 0.0034 0.0154 0.0495
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0756 0.2692
Mycobacterium leprae Conserved hypothetical protein 0.0077 0.0625 0.1597
Echinococcus granulosus GPCR family 2 0.0032 0.0126 0.0268
Schistosoma mansoni integrin alpha 0.0121 0.11 0.637
Loa Loa (eye worm) calpain family protein 1 0.0074 0.0589 0.2135
Loa Loa (eye worm) hypothetical protein 0.0141 0.1322 0.4794
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.1018 0.1001
Mycobacterium leprae Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0341 0.3517 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0881 0.3195
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0113 0.1018 1
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0341 0.3517 0.5
Loa Loa (eye worm) hypothetical protein 0.0095 0.0815 0.2957
Loa Loa (eye worm) hypothetical protein 0.0074 0.0589 0.2135
Plasmodium falciparum phd finger protein, putative 0.0028 0.0088 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0078 0.063 0.3605
Brugia malayi RNA binding protein 0.006 0.0432 0.151
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0022 0.0018 0.5
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0309 0.0724
Echinococcus multilocularis protein dispatched 1 0.0055 0.0385 0.0367
Brugia malayi hypothetical protein 0.0272 0.2758 1
Loa Loa (eye worm) RNA binding protein 0.006 0.0432 0.1567
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0018 0.5
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0126 0.0268
Schistosoma mansoni hypothetical protein 0.0026 0.0061 0.0251
Echinococcus granulosus geminin 0.0177 0.1716 0.4224
Echinococcus multilocularis tumor protein p63 0.0388 0.4037 0.4026
Echinococcus granulosus survival motor neuron protein 1 0.0272 0.2758 0.6818
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0076 1
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0341 0.3517 1
Echinococcus multilocularis calpain A 0.0078 0.063 0.0613
Loa Loa (eye worm) hypothetical protein 0.0032 0.0126 0.0457
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0274
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0385 0.1337
Echinococcus granulosus jumonji domain containing protein 0.004 0.021 0.0478
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0076 0.0215
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0076 0.0209
Onchocerca volvulus 0.0052 0.0347 0.494
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0126 0.0394
Schistosoma mansoni hypothetical protein 0.0055 0.0385 0.2159
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0088 0.007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0221
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0154 0.0799
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0154 0.0558
Mycobacterium ulcerans hypothetical protein 0.0027 0.0076 0.0215
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0091 0.0777 0.2771
Echinococcus multilocularis muscleblind protein 0.0141 0.1322 0.1306
Loa Loa (eye worm) hypothetical protein 0.0028 0.0085 0.031
Schistosoma mansoni hypothetical protein 0.0069 0.0532 0.3024
Plasmodium vivax calpain, putative 0.0022 0.0018 0.2075
Trypanosoma cruzi kinesin, putative 0.0022 0.0018 0.5
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0076 0.0209
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0088 0.0174
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0076 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0309 0.1122
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0018 0.5
Loa Loa (eye worm) hypothetical protein 0.0272 0.2758 1
Brugia malayi Muscleblind-like protein 0.0141 0.1322 0.4759
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0126 0.0108
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0018 0.5
Echinococcus multilocularis geminin 0.0177 0.1716 0.1701
Echinococcus granulosus Niemann Pick C1 protein 0.0162 0.1551 0.3813
Brugia malayi Kelch motif family protein 0.0038 0.0188 0.0621
Loa Loa (eye worm) hypothetical protein 0.0074 0.0589 0.2135
Echinococcus multilocularis protein patched 0.0049 0.0309 0.0292
Onchocerca volvulus 0.0077 0.0625 1
Echinococcus multilocularis integrin alpha 3 0.0092 0.0791 0.0774
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0756 0.4344
Echinococcus granulosus tumor protein p63 0.0388 0.4037 1
Brugia malayi hypothetical protein 0.0038 0.0188 0.0621
Echinococcus granulosus calpain A 0.0078 0.063 0.1523
Echinococcus granulosus expressed conserved protein 0.0106 0.0943 0.23
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0046 0.0163
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0076 0.0215
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0881 0.315
Schistosoma mansoni hypothetical protein 0.0047 0.029 0.1601
Echinococcus multilocularis Niemann Pick C1 protein 0.0162 0.1551 0.1535
Schistosoma mansoni integrin beta subunit 0.0145 0.1372 0.7977
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0018 0.5
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0078 0.063 0.3605
Mycobacterium tuberculosis Long conserved protein 0.0077 0.0625 0.1778
Loa Loa (eye worm) hypothetical protein 0.0141 0.1322 0.4794
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0798 0.0781
Echinococcus multilocularis jumonji domain containing protein 0.004 0.021 0.0192
Echinococcus granulosus integrin alpha ps 0.0026 0.0061 0.0106
Schistosoma mansoni hypothetical protein 0.0177 0.1716 1
Brugia malayi jmjC domain containing protein 0.0093 0.0798 0.2844
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0126 0.0108
Echinococcus multilocularis integrin alpha ps 0.0054 0.037 0.0352
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0078 0.063 0.0613
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0274
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0078 0.063 0.1523
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0756 0.4344
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0756 0.4344
Echinococcus multilocularis calpain family protein 1, d 0.0052 0.0347 0.0329
Brugia malayi CHE-14 protein 0.0049 0.0309 0.1062
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0341 0.3517 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0018 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0018 0.5
Loa Loa (eye worm) hypothetical protein 0.0038 0.0188 0.0683
Schistosoma mansoni hypothetical protein 0.0047 0.029 0.1601
Schistosoma mansoni hypothetical protein 0.0028 0.0088 0.0412
Brugia malayi TAR-binding protein 0.006 0.0432 0.151
Schistosoma mansoni integrin alpha-ps 0.0054 0.037 0.207
Loa Loa (eye worm) hypothetical protein 0.0113 0.1018 0.3691
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0018 0.5
Schistosoma mansoni hypothetical protein 0.0077 0.0625 0.3576
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.0018 0.5
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.0018 0.5
Echinococcus granulosus Transglutaminase 0.0077 0.0625 0.1511
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0154 0.0136
Echinococcus multilocularis integrin alpha ps 0.0054 0.037 0.0352
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0309 0.0724
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0076 0.0215
Trypanosoma brucei antigen, putative 0.0022 0.0018 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0881 0.315
Loa Loa (eye worm) hypothetical protein 0.0067 0.0507 0.1837
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0088 0.032
Echinococcus granulosus peregrin 0.0028 0.0088 0.0174
Mycobacterium ulcerans hypothetical protein 0.0077 0.0625 0.1778
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0022 0.0018 0.5
Onchocerca volvulus 0.0055 0.0385 0.5624
Trypanosoma brucei calpain-like protein, putative 0.0022 0.0018 0.5
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) 0.013 0.1199 0.5
Schistosoma mansoni hypothetical protein 0.0032 0.0126 0.0635
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.04 0.2249
Mycobacterium leprae Conserved hypothetical protein 0.0077 0.0625 0.1597

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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