Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0985 | 0.1206 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0107 | 0.1852 | 0.1671 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0083 | 0.139 | 0.6963 |
Trypanosoma brucei | polo-like protein kinase | 0.0107 | 0.1852 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0106 | 0.1822 | 0.2199 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0384 | 0.0478 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0083 | 0.139 | 0.1221 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.0034 | 0.0019 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0331 | 0.6373 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.061 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.004 | 0.0562 | 0.0662 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.1097 | 0.1315 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0331 | 0.6373 |
Schistosoma mansoni | jumonji domain containing protein | 0.0086 | 0.1446 | 0.1759 |
Brugia malayi | Pre-SET motif family protein | 0.0429 | 0.803 | 1 |
Brugia malayi | 4-aminobutyrate aminotransferase, mitochondrial precursor | 0.0021 | 0.0193 | 0.024 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0107 | 0.1852 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.0428 | 0.0533 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0083 | 0.139 | 0.0912 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0021 | 0.0193 | 0.0213 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0106 | 0.1822 | 0.2199 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0532 | 0.064 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.139 | 0.1712 |
Plasmodium vivax | SET domain protein, putative | 0.0062 | 0.0985 | 0.7008 |
Brugia malayi | beta-lactamase | 0.0083 | 0.139 | 0.1731 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0331 | 0.0412 |
Onchocerca volvulus | 0.0488 | 0.9166 | 1 | |
Mycobacterium tuberculosis | Probable hydrolase | 0.0083 | 0.139 | 0.1221 |
Mycobacterium tuberculosis | Conserved protein | 0.0083 | 0.139 | 0.1221 |
Echinococcus granulosus | ornithine aminotransferase | 0.0021 | 0.0193 | 0.0213 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.1097 | 0.1347 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0037 | 0.0499 | 0.3591 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0107 | 0.1852 | 0.2235 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0134 | 0.0141 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0037 | 0.0499 | 0.0586 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.0034 | 0.0019 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1852 | 0.1452 |
Mycobacterium tuberculosis | Probable aminotransferase | 0.0147 | 0.2611 | 0.2466 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.1097 | 0.1335 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1852 | 0.1452 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.0812 | 0.0236 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0042 | 0.0595 | 0.0703 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.0957 | 0.6883 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0532 | 0.0662 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0134 | 0.0141 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0033 | 0.0428 | 0.3078 |
Mycobacterium ulcerans | hypothetical protein | 0.0083 | 0.139 | 0.495 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.0524 | 0.0338 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0062 | 0.0985 | 0.1178 |
Mycobacterium ulcerans | adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 0.0147 | 0.2611 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0062 | 0.0985 | 0.1178 |
Plasmodium vivax | hypothetical protein, conserved | 0.0083 | 0.139 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0083 | 0.139 | 0.0912 |
Brugia malayi | PHD-finger family protein | 0.0033 | 0.0428 | 0.0533 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1852 | 0.1452 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0083 | 0.139 | 0.0912 |
Mycobacterium tuberculosis | Conserved protein | 0.0083 | 0.139 | 0.1221 |
Mycobacterium ulcerans | hypothetical protein | 0.0147 | 0.2611 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0331 | 0.2179 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0034 | 0.0041 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1852 | 0.1452 |
Brugia malayi | Augmenter of liver regeneration | 0.0037 | 0.0499 | 0.0622 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0418 | 0.0487 |
Schistosoma mansoni | ornithine--oxo-acid transaminase | 0.0021 | 0.0193 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.139 | 0.1712 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.061 | 0.4386 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0439 | 0.822 | 1 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0037 | 0.0499 | 0.0586 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1852 | 0.1452 |
Echinococcus multilocularis | ornithine aminotransferase | 0.0021 | 0.0193 | 0.0213 |
Brugia malayi | jmjC domain containing protein | 0.0042 | 0.0595 | 0.0741 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0134 | 0.0164 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0106 | 0.1822 | 0.2199 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.1852 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0106 | 0.1822 | 0.2217 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.1097 | 0.1315 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0037 | 0.0499 | 0.1104 |
Schistosoma mansoni | hypothetical protein | 0.0439 | 0.822 | 1 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0037 | 0.0499 | 0.1104 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.061 | 0.0742 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0083 | 0.139 | 0.1691 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0134 | 0.0164 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.1097 | 0.1335 |
Trichomonas vaginalis | acetylornithine aminotransferase, putative | 0.0147 | 0.2611 | 0.2339 |
Onchocerca volvulus | 0.0083 | 0.139 | 0.1146 | |
Echinococcus granulosus | dnaJ subfamily B | 0.0439 | 0.822 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.1097 | 0.1347 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0037 | 0.0499 | 0.2695 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0144 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.061 | 0.0721 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0083 | 0.139 | 0.1672 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.139 | 0.1712 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0062 | 0.0985 | 0.1198 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0874 | 0.1067 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0418 | 0.0508 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0138 | 0.2448 | 0.3032 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0418 | 0.0487 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.1097 | 0.1367 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.061 | 0.1832 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.1097 | 0.1347 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0037 | 0.0499 | 0.06 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0037 | 0.0499 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0042 | 0.0595 | 0.072 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0384 | 0.0456 |
Onchocerca volvulus | 0.0083 | 0.139 | 0.1146 | |
Mycobacterium tuberculosis | Conserved protein | 0.0083 | 0.139 | 0.1221 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0046 | 0.0677 | 0.0802 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0033 | 0.0428 | 0.0499 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1852 | 0.1452 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0106 | 0.1822 | 0.2217 |
Trichomonas vaginalis | set domain proteins, putative | 0.0488 | 0.9166 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0083 | 0.139 | 0.1221 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0134 | 0.0141 |
Brugia malayi | beta-lactamase family protein | 0.0083 | 0.139 | 0.1731 |
Onchocerca volvulus | 0.0083 | 0.139 | 0.1146 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.1852 | 0.1452 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0083 | 0.139 | 0.1712 |
Brugia malayi | beta-lactamase family protein | 0.0083 | 0.139 | 0.1731 |
Leishmania major | hypothetical protein, conserved | 0.0083 | 0.139 | 0.6963 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.061 | 0.1723 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0107 | 0.1852 | 0.2235 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0068 | 0.1091 | 0.1327 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0083 | 0.139 | 0.1221 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0882 | 0.1078 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0037 | 0.0499 | 0.342 |
Plasmodium vivax | ornithine aminotransferase, putative | 0.0021 | 0.0193 | 0.1159 |
Echinococcus granulosus | Aminotransferase class III | 0.0021 | 0.0193 | 0.0213 |
Brugia malayi | jmjC domain containing protein | 0.0108 | 0.1874 | 0.2334 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0331 | 0.2382 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.1097 | 0.1335 |
Mycobacterium leprae | Probable lipase LipE | 0.0083 | 0.139 | 0.495 |
Brugia malayi | MH2 domain containing protein | 0.0138 | 0.2448 | 0.3049 |
Giardia lamblia | Kinase, PLK | 0.0107 | 0.1852 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.139 | 0.1712 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0134 | 0.0141 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0012 | 0.0031 | 0.0015 |
Toxoplasma gondii | ornithine aminotransferase, mitochondrial precursor, putative | 0.0021 | 0.0193 | 0.1389 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0083 | 0.139 | 0.1221 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0106 | 0.1822 | 0.2217 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0108 | 0.1874 | 0.2262 |
Toxoplasma gondii | ABC1 family protein | 0.0083 | 0.139 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0046 | 0.0677 | 0.0802 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.139 | 0.1712 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0874 | 0.1088 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.061 | 0.0742 |
Chlamydia trachomatis | glutamate-1-semialdehyde-2,1-aminomutase | 0.0021 | 0.0193 | 0.5 |
Brugia malayi | PHD-finger family protein | 0.0013 | 0.0034 | 0.0042 |
Plasmodium falciparum | ornithine aminotransferase | 0.0021 | 0.0193 | 0.339 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0083 | 0.139 | 0.1691 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0033 | 0.0428 | 0.3078 |
Mycobacterium ulcerans | lipase LipD | 0.0083 | 0.139 | 0.495 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0107 | 0.1852 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0532 | 0.0647 |
Mycobacterium leprae | conserved hypothetical protein | 0.0083 | 0.139 | 0.495 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0134 | 0.0167 |
Onchocerca volvulus | 0.0062 | 0.0985 | 0.0684 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.1097 | 0.1335 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0331 | 0.1788 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.1097 | 0.1335 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.061 | 0.0738 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0428 | 0.0521 |
Loa Loa (eye worm) | beta-lactamase | 0.0083 | 0.139 | 0.1712 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0083 | 0.139 | 0.495 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0062 | 0.0985 | 0.7085 |
Brugia malayi | RNA binding protein | 0.0068 | 0.1097 | 0.1367 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.061 | 0.1832 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.1097 | 0.1367 |
Brugia malayi | Inositol-1 | 0.0043 | 0.061 | 0.0759 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0033 | 0.0428 | 0.0511 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0037 | 0.0499 | 0.3591 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.061 | 0.3292 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0021 | 0.019 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0331 | 0.039 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0062 | 0.0985 | 0.1178 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0083 | 0.139 | 0.495 |
Mycobacterium leprae | PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA | 0.0147 | 0.2611 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0068 | 0.1105 | 0.1356 |
Plasmodium falciparum | phd finger protein, putative | 0.0033 | 0.0428 | 0.8462 |
Mycobacterium tuberculosis | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 0.0147 | 0.2611 | 0.2466 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0083 | 0.139 | 0.7506 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.139 | 0.1712 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0428 | 0.0511 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.061 | 0.0721 |
Brugia malayi | hypothetical protein | 0.0018 | 0.014 | 0.0175 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0138 | 0.2448 | 0.3032 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0083 | 0.139 | 0.1672 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.061 | 0.1832 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0134 | 0.0164 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0429 | 0.803 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.0812 | 0.0236 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0062 | 0.0985 | 0.1198 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0042 | 0.0595 | 0.0724 |
Brugia malayi | Pre-SET motif family protein | 0.0062 | 0.0985 | 0.1226 |
Echinococcus multilocularis | peregrin | 0.0033 | 0.0428 | 0.0499 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0083 | 0.139 | 0.6963 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0106 | 0.1822 | 0.2269 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0083 | 0.139 | 0.1221 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0928 | 0.1109 |
Echinococcus granulosus | peregrin | 0.0033 | 0.0428 | 0.0499 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0106 | 0.1822 | 0.2251 |
Onchocerca volvulus | Alhambra homolog | 0.0033 | 0.0428 | 0.005 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.1852 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0107 | 0.1852 | 0.2306 |
Mycobacterium ulcerans | beta-lactamase | 0.0083 | 0.139 | 0.495 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0022 | 0.0224 | 0.0279 |
Echinococcus multilocularis | Aminotransferase class III | 0.0021 | 0.0193 | 0.0213 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0012 | 0.0031 | 0.0015 |
Schistosoma mansoni | kinase | 0.0055 | 0.0839 | 0.1021 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0874 | 0.1088 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.0524 | 0.1369 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0106 | 0.1822 | 0.2199 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0134 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0034 | 0.0019 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.0428 | 0.2894 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0384 | 0.0467 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0107 | 0.1852 | 0.2288 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0134 | 0.0167 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0108 | 0.1874 | 0.2262 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0083 | 0.139 | 0.1731 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0874 | 0.1067 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0062 | 0.0985 | 0.1198 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0499 | 0.1104 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.1852 | 0.2253 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0418 | 0.0508 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0033 | 0.0428 | 0.0499 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0083 | 0.139 | 0.0912 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0042 | 0.0595 | 0.0724 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0037 | 0.0499 | 0.1104 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0083 | 0.139 | 0.0912 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0134 | 0.0164 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0083 | 0.139 | 0.1221 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0134 | 0.0141 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0134 | 0.0141 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0062 | 0.0985 | 0.1198 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0033 | 0.0428 | 0.0521 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0083 | 0.139 | 0.0912 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | Agonist activity at human recombinant 5HT2B receptor by cell-based system | ChEMBL. | 19269173 | |
Emax (functional) | = 18 % | Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization at 10 uM by FLIPR assay relative to serotonin | ChEMBL. | 19269173 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.