Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor II (thrombin) | Starlite/ChEMBL | References |
Homo sapiens | coagulation factor X | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0072 | 0.0311 | 0.0344 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.012 | 0.0133 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.0503 | 0.0503 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0068 | 0.0114 |
Schistosoma mansoni | patched 1 | 0.0086 | 0.0399 | 0.0462 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0086 | 0.0399 | 0.0668 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0095 | 0.0158 |
Mycobacterium ulcerans | integral membrane transporter | 0.0032 | 0.0068 | 0.0075 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.012 | 0.0201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.012 | 0.0133 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.0503 | 0.0843 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.032 | 0.0371 |
Brugia malayi | AMP-binding enzyme family protein | 0.0072 | 0.0311 | 0.052 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.012 | 0.0133 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.0233 | 0.1297 | 0.2255 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0041 | 0.012 | 0.0209 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.0494 | 0.0827 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0438 | 0.2558 | 0.4285 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.0503 | 0.0584 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.007 | 0.0303 | 0.0507 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0494 | 0.0827 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0086 | 0.0399 | 0.0668 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0095 | 0.0158 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0095 | 0.0095 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0248 | 0.1392 | 0.2332 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0041 | 0.012 | 0.0209 |
Onchocerca volvulus | 0.0041 | 0.012 | 0.1086 | |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0995 | 0.5971 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.012 | 0.0209 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.012 | 0.0133 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.1427 | 0.8622 | 1 |
Mycobacterium leprae | Probable transmembrane transport protein | 0.0233 | 0.1297 | 0.1504 |
Echinococcus granulosus | expressed conserved protein | 0.0133 | 0.0688 | 0.1151 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0095 | 0.0158 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0438 | 0.2558 | 0.4285 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0071 | 0.0083 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0068 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0073 | 0.032 | 0.0536 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0068 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.2558 | 0.4285 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.0503 | 0.0584 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.032 | 0.0371 |
Brugia malayi | CHE-14 protein | 0.0086 | 0.0399 | 0.0668 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 0.0303 | 0.0507 |
Echinococcus multilocularis | carbonic anhydrase | 0.0438 | 0.2558 | 0.2558 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0086 | 0.0399 | 0.0442 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0032 | 0.0068 | 0.0113 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.012 | 0.012 |
Echinococcus granulosus | sentrin specific protease 7 | 0.0146 | 0.0766 | 0.1282 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0072 | 0.0311 | 0.0344 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.012 | 0.0201 |
Leishmania major | cathepsin L-like protease | 0.007 | 0.0303 | 0.0351 |
Echinococcus granulosus | carbonic anhydrase II | 0.0995 | 0.5971 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0068 | 0.0079 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0095 | 0.011 |
Echinococcus granulosus | carbonic anhydrase | 0.0438 | 0.2558 | 0.4285 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0068 | 0.0114 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.032 | 0.0371 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0438 | 0.2558 | 0.4285 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0181 | 0.021 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0095 | 0.037 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.038 | 0.044 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0041 | 0.012 | 0.0209 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0182 | 0.0316 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0001 | 0.0002 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0287 | 0.1628 | 0.1628 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.012 | 0.0201 |
Leishmania major | carbonic anhydrase-like protein | 0.0995 | 0.5971 | 0.6925 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0156 | 0.0827 | 0.1385 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0438 | 0.2558 | 0.4285 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0146 | 0.0766 | 0.0888 |
Mycobacterium leprae | conserved hypothetical protein | 0.0041 | 0.012 | 0.0139 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.0959 | 0.5751 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.0438 | 0.2558 | 0.4285 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 0.0303 | 0.0507 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0201 | 0.1101 | 0.1844 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0021 | 0.0001 | 0.0001 |
Plasmodium falciparum | inorganic anion exchanger, inorganic anion antiporter | 0.0032 | 0.0068 | 0.0264 |
Leishmania major | cathepsin L-like protease | 0.007 | 0.0303 | 0.0351 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0095 | 0.011 |
Schistosoma mansoni | carbonic anhydrase | 0.1427 | 0.8622 | 1 |
Echinococcus granulosus | expressed conserved protein | 0.0188 | 0.1026 | 0.1719 |
Onchocerca volvulus | Putative sulfate transporter | 0.0201 | 0.1105 | 1 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0201 | 0.1101 | 0.1844 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0072 | 0.0311 | 0.0344 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0068 | 0.0114 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0068 | 0.0079 |
Onchocerca volvulus | 0.0041 | 0.012 | 0.1086 | |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.012 | 0.0133 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0095 | 0.0158 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.0181 | 0.021 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0072 | 0.0311 | 0.036 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0072 | 0.0311 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.012 | 0.0201 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0032 | 0.0068 | 0.0113 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0001 | 0.0002 |
Mycobacterium ulcerans | transmembrane carbonic anhydrase, SulP | 0.0032 | 0.0068 | 0.0075 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.0503 | 0.0584 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0055 | 0.021 | 0.0352 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0086 | 0.0399 | 0.0668 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0095 | 0.0158 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0054 | 0.0199 | 0.0221 |
Plasmodium vivax | sulfate transporter, putative | 0.0032 | 0.0068 | 0.3385 |
Toxoplasma gondii | hypothetical protein | 0.0438 | 0.2558 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0095 | 0.0105 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1427 | 0.8622 | 0.9551 |
Echinococcus multilocularis | carbonic anhydrase | 0.0438 | 0.2558 | 0.2558 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.2558 | 0.4285 |
Echinococcus multilocularis | protein dispatched 1 | 0.0098 | 0.0473 | 0.0473 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1494 | 0.9028 | 1 |
Plasmodium falciparum | carbonic anhydrase | 0.0438 | 0.2558 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0438 | 0.2558 | 0.2967 |
Echinococcus granulosus | carbonic anhydrase | 0.0438 | 0.2558 | 0.4285 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0054 | 0.0199 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0438 | 0.2558 | 0.4285 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.012 | 0.0201 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0021 | 0.0001 | 0.0002 |
Toxoplasma gondii | inorganic anion transporter, sulfate permease (SulP) family protein | 0.0032 | 0.0068 | 0.0264 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1427 | 0.8622 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1494 | 0.9028 | 1 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1427 | 0.8622 | 1 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0021 | 0.0001 | 0.0005 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0201 | 0.1101 | 0.1277 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0995 | 0.5971 | 0.6925 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0199 | 0.0334 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0072 | 0.0311 | 0.036 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0068 | 0.0114 |
Trypanosoma brucei | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0032 | 0.0068 | 0.0113 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.032 | 0.0371 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0995 | 0.5971 | 1 |
Echinococcus multilocularis | protein patched | 0.0086 | 0.0399 | 0.0399 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0995 | 0.5971 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0438 | 0.2558 | 0.2967 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.038 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0311 | 0.052 |
Schistosoma mansoni | hypothetical protein | 0.0438 | 0.2558 | 0.2967 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0201 | 0.1101 | 0.1101 |
Mycobacterium ulcerans | transmembrane carbonic anhydrase, SulP | 0.0032 | 0.0068 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.012 | 0.0201 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0041 | 0.012 | 0.0209 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0995 | 0.5971 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0072 | 0.0311 | 0.0344 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0041 | 0.012 | 0.0209 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.012 | 0.0133 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.012 | 0.0133 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0041 | 0.012 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.1101 | 0.1844 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0068 | 0.0079 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0995 | 0.5971 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0311 | 0.0344 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0068 | 0.0068 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0071 | 0.0124 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0297 | 0.0497 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0072 | 0.0311 | 0.036 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.012 | 0.0133 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0199 | 0.0334 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0072 | 0.0311 | 0.0344 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.032 | 0.032 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.2558 | 0.4285 |
Onchocerca volvulus | 0.0072 | 0.0311 | 0.2811 | |
Toxoplasma gondii | kringle domain-containing protein | 0.0021 | 0.0001 | 0.0005 |
Onchocerca volvulus | 0.0051 | 0.0181 | 0.1639 | |
Echinococcus multilocularis | carbonic anhydrase | 0.0438 | 0.2558 | 0.2558 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.012 | 0.0469 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0072 | 0.0311 | 0.054 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0995 | 0.5971 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.012 | 0.0139 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.007 | 0.0303 | 0.0507 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.038 | 0.044 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0095 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.038 | 0.044 |
Brugia malayi | Protein kinase domain containing protein | 0.0021 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.012 | 0.0201 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.026 | 0.1462 | 0.2543 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.012 | 0.0139 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.012 | 0.0201 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0103 | 0.0503 | 0.0843 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.012 | 0.0201 |
Leishmania major | cathepsin L-like protease | 0.007 | 0.0303 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0517 | 0.0867 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.012 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0199 | 0.0334 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0199 | 0.0334 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0021 | 0.0001 | 0.0002 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0182 | 0.0316 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.012 | 0.0201 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0068 | 0.0114 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.0503 | 0.0503 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.032 | 0.0536 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.0181 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0068 | 0.0114 |
Echinococcus multilocularis | expressed conserved protein | 0.0133 | 0.0688 | 0.0688 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0204 | 0.112 | 0.1299 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.032 | 0.0371 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0182 | 0.0316 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0438 | 0.2558 | 0.2967 |
Onchocerca volvulus | 0.0041 | 0.012 | 0.1086 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0072 | 0.0311 | 0.036 |
Brugia malayi | hypothetical protein | 0.0248 | 0.1392 | 0.2332 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.012 | 0.0139 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0095 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0072 | 0.0311 | 0.054 |
Echinococcus multilocularis | sentrin specific protease 7 | 0.0146 | 0.0766 | 0.0766 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0095 | 0.011 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0103 | 0.0503 | 0.0843 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0095 | 0.011 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0072 | 0.0311 | 0.036 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0054 | 0.0199 | 0.078 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0072 | 0.0311 | 0.036 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0311 | 0.052 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.0494 | 0.0827 |
Brugia malayi | AMP-binding enzyme family protein | 0.0072 | 0.0311 | 0.052 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0095 | 0.0105 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.0503 | 0.0843 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0041 | 0.012 | 0.0209 |
Schistosoma mansoni | carbonic anhydrase | 0.0438 | 0.2558 | 0.2967 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0146 | 0.0766 | 0.0888 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0767 | 0.4574 | 0.7954 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0287 | 0.1628 | 0.2727 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0095 | 0.0105 |
Brugia malayi | beta-lactamase | 0.0041 | 0.012 | 0.0201 |
Onchocerca volvulus | 0.0021 | 0.0001 | 0.0012 | |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0893 | 0.5345 | 0.9295 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0068 | 0.0114 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0064 | 0.0265 | 0.0444 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1494 | 0.9028 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0297 | 0.0344 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.012 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0311 | 0.052 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0072 | 0.0311 | 0.036 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.012 | 0.0201 |
Loa Loa (eye worm) | STAT protein | 0.0156 | 0.0827 | 0.1385 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0021 | 0.0001 | 0.0002 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0086 | 0.0399 | 0.0399 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.012 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.1392 | 0.2332 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0054 | 0.0199 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0199 | 0.0334 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.012 | 0.0133 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0438 | 0.2558 | 0.4285 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.012 | 0.0201 |
Mycobacterium leprae | Probable lipase LipE | 0.0041 | 0.012 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.012 | 0.0201 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0248 | 0.1392 | 0.1392 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0072 | 0.0311 | 0.0344 |
Leishmania major | hypothetical protein, conserved | 0.0021 | 0.0001 | 0.0002 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0995 | 0.5971 | 0.5971 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0995 | 0.5971 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.007 | 0.0303 | 0.0507 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.012 | 0.0209 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0095 | 0.0158 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0995 | 0.5971 | 0.6925 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.012 | 0.6015 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.032 | 0.0371 |
Echinococcus multilocularis | expressed conserved protein | 0.0188 | 0.1026 | 0.1026 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0399 | 0.0668 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0068 | 0.0079 |
Onchocerca volvulus | 0.0201 | 0.1105 | 1 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0182 | 0.0316 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.0494 | 0.0827 |
Brugia malayi | AMP-binding enzyme family protein | 0.0072 | 0.0311 | 0.052 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0297 | 0.0497 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0054 | 0.0199 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.012 | 0.0133 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.012 | 0.0201 |
Brugia malayi | Kringle domain containing protein | 0.0021 | 0.0001 | 0.0002 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0021 | 0.0001 | 0.0067 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0072 | 0.0311 | 0.036 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.