Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0835 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0129 | 1 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0792 | 0.151 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2703 | 0.539 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.2166 | 0.4427 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.2703 | 0.5652 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.2703 | 0.2703 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0835 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0792 | 0.1287 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0835 | 0.0835 |
Echinococcus granulosus | zinc finger protein | 0.0022 | 0.0488 | 0.0592 |
Brugia malayi | Bromodomain containing protein | 0.0086 | 0.6175 | 0.6175 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0129 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.2703 | 0.2531 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.5736 | 0.5636 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0596 | 0.0376 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0068 | 0.4605 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0229 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0596 | 0.1112 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2855 | 0.2688 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.1035 | 0.1035 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.2659 | 0.2487 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0835 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.2703 | 0.5652 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0835 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.2703 | 0.5652 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0229 | 0.0366 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.0292 | 0.0064 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.2409 | 0.2409 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0835 | 0.062 |
Schistosoma mansoni | bromodomain containing protein | 0.0073 | 0.4972 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0835 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.2703 | 0.5652 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0835 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0022 | 0.0488 | 0.0891 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.2166 | 0.4427 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0835 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.0022 | 0.0488 | 0.0592 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0835 | 0.5 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0229 | 0.0366 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2703 | 0.539 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0792 | 0.1287 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2703 | 0.539 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0229 | 0.0366 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0068 | 0.4605 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2416 | 0.2239 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.