Detailed information for compound 1038931

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 170.618 | Formula: C3H7ClN2O2S
  • H donors: 2 H acceptors: 2 LogP: 0.57 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CSC(=N)N.Cl
  • InChi: 1S/C3H6N2O2S.ClH/c4-3(5)8-1-2(6)7;/h1H2,(H3,4,5)(H,6,7);1H
  • InChiKey: DZLYRGFLNXMMIT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Schistosoma mansoni glutamate receptor NMDA 0.0878 0.2747 0.3861
Trichomonas vaginalis DNA helicase recq, putative 0.0028 0.0032 0.1452
Schistosoma mansoni glutamate receptor NMDA 0.1007 0.3161 0.4442
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0109 0.029 1
Echinococcus multilocularis bloom syndrome protein 0.0028 0.0032 0.0041
Brugia malayi hypothetical protein 0.0197 0.0572 0.0569
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0202 0.0199
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0568 0.1757 0.2467
Brugia malayi Metabotropic glutamate receptor precursor. 0.0049 0.0098 0.0095
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0568 0.1757 0.2467
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0049 0.0098 0.0134
Brugia malayi Cytochrome P450 family protein 0.0023 0.0016 0.0013
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0049 0.0098 0.0095
Onchocerca volvulus 0.0109 0.029 1
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0099 0.4824
Echinococcus multilocularis glutamate receptor 2 0.0376 0.1143 0.1604
Schistosoma mansoni glutamate receptor AMPA 0.0519 0.1602 0.2249
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0049 0.0098 0.0095
Loa Loa (eye worm) hypothetical protein 0.0109 0.029 0.0287
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0024 0.0169
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0156 0.1238
Echinococcus granulosus metabotropic glutamate receptor 2 0.0049 0.0098 0.0134
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0091 0.0088
Plasmodium vivax hypothetical protein, conserved 0.0109 0.029 1
Loa Loa (eye worm) hypothetical protein 0.3148 1 1
Plasmodium falciparum deoxyhypusine synthase 0.0069 0.0162 0.5549
Trypanosoma cruzi deoxyhypusine synthase, putative 0.0026 0.0026 0.0023
Echinococcus granulosus receptor type guanylyl cyclase 0.0049 0.0098 0.0134
Mycobacterium ulcerans oxidoreductase 0.0109 0.029 0.2323
Echinococcus multilocularis chromobox protein 1 0.0081 0.0202 0.0279
Echinococcus multilocularis NMDA receptor 0.0192 0.0556 0.0779
Brugia malayi deoxyhypusine synthase 0.0069 0.0162 0.0159
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0003 0.0037
Schistosoma mansoni protein kinase 0.0049 0.0098 0.0134
Schistosoma mansoni blooms syndrome DNA helicase 0.0022 0.0013 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0202 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0088 0.0085
Onchocerca volvulus 0.0036 0.0056 0.1861
Echinococcus granulosus bloom syndrome protein 0.0028 0.0032 0.0041
Onchocerca volvulus 0.0049 0.0098 0.3309
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0098 0.0095
Plasmodium falciparum protoporphyrinogen oxidase 0.0109 0.029 1
Schistosoma mansoni ATP-binding cassette transporter 0.0519 0.1602 0.2249
Leishmania major deoxyhypusine synthase, putative 0.0069 0.0162 0.0159
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Plasmodium vivax deoxyhypusine synthase, putative 0.0069 0.0162 0.555
Echinococcus multilocularis receptor type guanylyl cyclase 0.0049 0.0098 0.0134
Plasmodium vivax calcium-transporting ATPase, putative 0.0019 0.0003 0.0002
Loa Loa (eye worm) glutamate receptor 0.0049 0.0098 0.0095
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0019 0.0003 0.0033
Schistosoma mansoni glutamate receptor kainate 0.0519 0.1602 0.2249
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0024 0.0169
Brugia malayi Bloom's syndrome protein homolog 0.0028 0.0032 0.0029
Loa Loa (eye worm) hypothetical protein 0.0141 0.0392 0.0389
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0091 0.0124
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0091 0.0124
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0098 0.0095
Echinococcus granulosus lysine specific histone demethylase 1A 0.0109 0.029 0.0404
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0019 0.0003 0.0033
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0088 0.2954
Echinococcus multilocularis chromobox protein 1 0.0081 0.0202 0.0279
Brugia malayi amine oxidase, flavin-containing family protein 0.0109 0.029 0.0287
Schistosoma mansoni metabotropic glutamate receptor 0.0049 0.0098 0.0134
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0109 0.029 1
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.1007 0.3161 0.4442
Echinococcus granulosus glutamate NMDA receptor subunit 0.1007 0.3161 0.4442
Brugia malayi hypothetical protein 0.0049 0.0098 0.0095
Leishmania major UDP-galactopyranose mutase 0.0109 0.029 0.0287
Trypanosoma cruzi C-8 sterol isomerase, putative 0.3148 1 1
Toxoplasma gondii histone lysine-specific demethylase 0.0109 0.029 1
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0003 0.0012
Onchocerca volvulus 0.0049 0.0098 0.3309
Echinococcus multilocularis microtubule associated protein 2 0.2244 0.7112 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0067 0.0156 0.0153
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0024 0.1313
Trypanosoma cruzi UDP-galactopyranose mutase 0.0109 0.029 0.0287
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0019 0.0003 0.0033
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0049 0.0098 0.0134
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0192 0.0556 0.0779
Plasmodium vivax P-type ATPase4, putative 0.0019 0.0003 0.0002
Echinococcus multilocularis glutamate receptor 2 0.0568 0.1757 0.2467
Echinococcus granulosus chromobox protein 1 0.0081 0.0202 0.0279
Brugia malayi metabotropic glutamate receptor type 2 0.0049 0.0098 0.0095
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0019 0.0003 0.0027
Schistosoma mansoni eyes absent homolog 0.0197 0.0572 0.0801
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0109 0.029 1
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0049 0.0098 0.0095
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0019 0.0003 0.0033
Toxoplasma gondii P-type ATPase PMA1 0.0019 0.0003 0.0027
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0099 0.3339
Entamoeba histolytica hypothetical protein 0.0049 0.0098 0.5963
Loa Loa (eye worm) glutamate receptor 1 0.0519 0.1602 0.1599
Schistosoma mansoni tyrosine kinase 0.0049 0.0098 0.0134
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0192 0.0556 0.0779
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0024 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0091 0.0124
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0016 0.0013
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0109 0.029 1
Brugia malayi Heterochromatin protein 1 0.0081 0.0202 0.0199
Trypanosoma cruzi extracellular receptor, putative 0.0049 0.0098 0.0095
Schistosoma mansoni chromobox protein 0.0081 0.0202 0.0279
Schistosoma mansoni hypothetical protein 0.0192 0.0556 0.0779
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0156 0.1238
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0192 0.0556 0.0779
Schistosoma mansoni metabotropic glutamate receptor 0.0049 0.0098 0.0134
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0024 0.0268
Entamoeba histolytica deoxyhypusine synthase, putative 0.0069 0.0162 1
Echinococcus granulosus glutamate receptor NMDA 0.031 0.0933 0.1308
Echinococcus granulosus nmda type glutamate receptor 0.0359 0.1088 0.1527
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0202 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0067 0.0156 0.1749
Mycobacterium ulcerans hypothetical protein 0.0025 0.0024 0.0169
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.0156 0.0153
Treponema pallidum cation-transporting ATPase, P-type 0.0019 0.0003 0.5
Loa Loa (eye worm) hypothetical protein 0.0109 0.029 0.0287
Echinococcus granulosus metabotropic glutamate receptor 5 0.0049 0.0098 0.0134
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0019 0.0003 0.0027
Mycobacterium tuberculosis Possible oxidoreductase 0.0109 0.029 0.3255
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0568 0.1757 0.2467
Loa Loa (eye worm) hypothetical protein 0.0197 0.0572 0.0569
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0019 0.0003 0.0027
Schistosoma mansoni tyrosine kinase 0.0049 0.0098 0.0134
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Schistosoma mansoni glutamate receptor kainate 0.0519 0.1602 0.2249
Echinococcus multilocularis nmda type glutamate receptor 0.0359 0.1088 0.1527
Loa Loa (eye worm) hypothetical protein 0.1609 0.5083 0.5082
Echinococcus multilocularis nmda type glutamate receptor 0.0502 0.1547 0.2172
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0091 0.0088
Loa Loa (eye worm) hypothetical protein 0.0109 0.029 0.0287
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0024 0.0169
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0019 0.0003 0.0033
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0109 0.029 0.0404
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0024 0.0169
Schistosoma mansoni chromobox protein 0.0081 0.0202 0.0279
Leishmania major C-8 sterol isomerase-like protein 0.3148 1 1
Echinococcus multilocularis glutamate receptor NMDA 0.031 0.0933 0.1308
Echinococcus multilocularis glutamate receptor 2 0.0519 0.1602 0.2249
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0049 0.0098 0.0095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0024 0.1313
Trypanosoma brucei C-8 sterol isomerase, putative 0.3148 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0091 0.0124
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0049 0.0098 0.3309
Leishmania major deoxyhypusine synthase;with=GeneDB:Linj34_V3.0350 0.0026 0.0026 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0091 0.0124
Loa Loa (eye worm) hypothetical protein 0.0197 0.0572 0.0569
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Echinococcus granulosus deoxyhypusine synthase 0.0069 0.0162 0.0224
Loa Loa (eye worm) glutamate receptor 2 0.0519 0.1602 0.1599
Brugia malayi hypothetical protein 0.0109 0.029 0.0287
Leishmania major extracellular receptor, putative 0.0049 0.0098 0.0095
Trichomonas vaginalis DNA helicase recq1, putative 0.0028 0.0032 0.1452
Trypanosoma cruzi deoxyhypusine synthase, putative 0.0026 0.0026 0.0023
Trypanosoma cruzi deoxyhypusine synthase, putative 0.0069 0.0162 0.0159
Echinococcus multilocularis deoxyhypusine synthase 0.0069 0.0162 0.0224
Brugia malayi SWIRM domain containing protein 0.0109 0.029 0.0287
Loa Loa (eye worm) hypothetical protein 0.0109 0.029 0.0287
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0067 0.0156 0.0215
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0192 0.0556 0.0779
Trypanosoma brucei deoxyhypusine synthase 0.0026 0.0026 0.0023
Plasmodium vivax cation transporting ATPase, putative 0.0019 0.0003 0.0002
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0405 0.1238 1
Plasmodium vivax hypothetical protein, conserved 0.0109 0.029 1
Toxoplasma gondii cation-transporting atpase family protein 0.0019 0.0003 0.0027
Plasmodium vivax copper-transporting ATPase, putative 0.0019 0.0003 0.0002
Chlamydia trachomatis protoporphyrinogen oxidase 0.0109 0.029 1
Loa Loa (eye worm) deoxyhypusine synthase 0.0069 0.0162 0.0159
Echinococcus granulosus glutamate receptor 2 0.0568 0.1757 0.2467
Echinococcus granulosus tyrosine kinase 0.0049 0.0098 0.0134
Brugia malayi chromobox protein homolog 3 0.0045 0.0088 0.0085
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0003 0.0012
Echinococcus granulosus nmda type glutamate receptor 0.0502 0.1547 0.2172
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0019 0.0003 0.0027
Giardia lamblia Deoxyhypusine synthase, putative 0.0069 0.0162 1
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0109 0.029 0.2323
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0024 0.0169
Echinococcus granulosus chromobox protein 1 0.0081 0.0202 0.0279
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0568 0.1757 0.2467
Brugia malayi Glutamate receptor 1 precursor 0.0519 0.1602 0.1599
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0091 0.0124
Echinococcus granulosus atrial natriuretic peptide receptor 0.0049 0.0098 0.0134
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0024 0.0729
Schistosoma mansoni amine oxidase 0.0109 0.029 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.2134
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0024 0.0021
Mycobacterium ulcerans dehydrogenase 0.0109 0.029 0.2323
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.0021 0.0627
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0568 0.1757 0.2467
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0091 0.0124
Toxoplasma gondii P-type ATPase4, putative 0.0019 0.0003 0.0027
Echinococcus granulosus glutamate receptor 2 0.0376 0.1143 0.1604
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0019 0.0003 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.2134
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0088 0.4269
Brugia malayi Guanylyl cyclase protein 23 0.0049 0.0098 0.0095
Brugia malayi Receptor family ligand binding region containing protein 0.0049 0.0098 0.0095
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0024 0.1313
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0024 0.0021
Brugia malayi Receptor family ligand binding region containing protein 0.0049 0.0098 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0024 0.0169
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0109 0.029 1
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0024 0.0021
Schistosoma mansoni amine oxidase 0.0109 0.029 0.0404
Echinococcus multilocularis protoporphyrinogen oxidase 0.0109 0.029 0.0404
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0019 0.0003 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0088 0.4269
Loa Loa (eye worm) RecQ helicase 0.0028 0.0032 0.0029
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0109 0.029 0.0404
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0568 0.1757 0.2467
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0568 0.1757 0.2467
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0021
Trichomonas vaginalis deoxyhypusine synthase, putative 0.0069 0.0162 0.8018
Toxoplasma gondii deoxyhypusine synthase 0.0069 0.0162 0.5561
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0156 0.0215
Entamoeba histolytica deoxyhypusine synthase, putative 0.0069 0.0162 1
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0024 0.0021
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0405 0.1238 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0003 0.0015
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0192 0.0556 0.0779
Schistosoma mansoni deoxyhypusine synthase 0.0069 0.0162 0.0224
Trypanosoma brucei deoxyhypusine synthase 0.0069 0.0162 0.0159
Mycobacterium ulcerans monoamine oxidase 0.0109 0.029 0.2323
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Loa Loa (eye worm) hypothetical protein 0.0109 0.029 0.0287
Schistosoma mansoni glutamate receptor AMPA 0.0519 0.1602 0.2249
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0141 0.0139
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0156 0.0215
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0024 0.0729
Trypanosoma cruzi UDP-galactopyranose mutase 0.0109 0.029 0.0287
Brugia malayi Glutamate receptor 2 precursor 0.0519 0.1602 0.1599
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0019 0.0003 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0024 0.0268
Loa Loa (eye worm) hypothetical protein 0.0036 0.0056 0.0053
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0024 0.0169
Mycobacterium tuberculosis Conserved hypothetical protein 0.0109 0.029 0.3255
Echinococcus multilocularis tyrosine kinase 0.0049 0.0098 0.0134
Schistosoma mansoni glutamate receptor kainate 0.0519 0.1602 0.2249
Echinococcus multilocularis 0.0109 0.029 0.0404
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0021
Echinococcus granulosus lysine specific histone demethylase 1A 0.0109 0.029 0.0404
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0109 0.029 0.0404
Schistosoma mansoni microtubule-associated protein tau 0.2244 0.7112 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0098 0.0095
Echinococcus granulosus microtubule associated protein 2 0.2244 0.7112 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0021
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0568 0.1757 0.2467
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0049 0.0098 0.0134
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0024 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0099 0.4824
Treponema pallidum hypothetical protein 0.0019 0.0003 0.5
Onchocerca volvulus 0.0025 0.0024 0.0729
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0192 0.0556 0.0779
Echinococcus granulosus glutamate receptor subunit protein glur 0.0192 0.0556 0.0779
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0297 0.0891 1
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0109 0.029 1
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0192 0.0556 0.0779
Loa Loa (eye worm) hypothetical protein 0.0109 0.029 0.0287
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0095

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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