Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein | 0.0063 | 0.007 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0037 | 0.0023 | 0.0023 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0932 | 0.1652 | 0.1652 |
Loa Loa (eye worm) | hypothetical protein | 0.5516 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0932 | 0.1652 | 0.1652 |
Brugia malayi | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.008 | 0.008 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.008 | 0.0674 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0025 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0031 | 0.0011 | 0.0058 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.001 | 0.001 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0352 | 0.0597 | 0.0597 |
Loa Loa (eye worm) | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.008 | 0.0065 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0037 | 0.0023 | 0.0023 |
Treponema pallidum | amino acid ABC transporter, periplasmic binding protein (hisJ) | 0.0063 | 0.007 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0011 | 0.0011 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0352 | 0.0597 | 0.0597 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0207 | 0.0333 | 0.0333 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | carboxylesterase | 0.5516 | 1 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0048 | 0.0043 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0025 | 0.0001 | 0.0001 |
Toxoplasma gondii | hypothetical protein | 0.0055 | 0.0055 | 0.0216 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0011 | 0.0011 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0088 | 0.0115 | 0.0115 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0011 | 0.0011 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0131 | 0.0194 | 0.2722 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0025 | 0.0001 | 0.0001 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0161 | 0.0248 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Onchocerca volvulus | 0.0031 | 0.0011 | 0.0058 | |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0164 | 0.0254 | 0.0254 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0011 | 0.0011 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.034 | 0.0574 | 0.9594 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | steroid hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.008 | 0.0065 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0932 | 0.1652 | 1 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0207 | 0.0333 | 0.0333 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0159 | 0.0246 | 0.0246 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0932 | 0.1652 | 0.1652 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0352 | 0.0597 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0932 | 0.1652 | 0.1652 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | lamin | 0.0031 | 0.0011 | 0.0011 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0062 | 0.0069 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0164 | 0.0254 | 0.0254 |
Leishmania major | 0.0352 | 0.0597 | 1 | |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0161 | 0.0248 | 0.3714 |
Loa Loa (eye worm) | carboxylesterase | 0.0932 | 0.1652 | 0.1652 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.5516 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.5516 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0011 | 0.0011 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0025 | 0.0001 | 0.0001 |
Leishmania major | mitochondrial DNA polymerase beta | 0.034 | 0.0574 | 0.9564 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0932 | 0.1652 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.5516 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.5516 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0161 | 0.0248 | 0.3714 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0164 | 0.0254 | 0.0254 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0025 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.008 | 0.0065 |
Onchocerca volvulus | 0.0932 | 0.1652 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0011 | 0.0011 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0025 | 0.0001 | 0.0001 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0352 | 0.0597 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.0302 | 0.0302 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0025 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0932 | 0.1652 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0932 | 0.1652 | 0.1652 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0055 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0025 | 0.0001 | 0.0001 |
Echinococcus granulosus | acetylcholinesterase | 0.5516 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0025 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0932 | 0.1652 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0025 | 0.0001 | 0.0001 |
Chlamydia trachomatis | glutamine binding protein | 0.0063 | 0.007 | 0.5 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0044 | 0.0036 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0932 | 0.1652 | 0.1652 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0037 | 0.0023 | 0.0023 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0011 | 0.0011 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0352 | 0.0597 | 0.0597 |
Brugia malayi | Cytochrome P450 family protein | 0.0055 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | acetylcholinesterase | 0.0932 | 0.1652 | 0.1652 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0932 | 0.1652 | 0.1652 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0037 | 0.0023 | 0.0023 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.034 | 0.0574 | 0.9594 |
Schistosoma mansoni | thyroid hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0044 | 0.0036 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0025 | 0.0001 | 0.0001 |
Echinococcus granulosus | glutamate receptor 2 | 0.0037 | 0.0023 | 0.0023 |
Echinococcus granulosus | FTZ F1 alpha | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | thyroid hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.008 | 0.008 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.5516 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0932 | 0.1652 | 0.1652 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | neuroligin | 0.0932 | 0.1652 | 0.1652 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.008 | 0.008 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0131 | 0.0194 | 0.2733 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0932 | 0.1652 | 0.1652 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0932 | 0.1652 | 0.1652 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0352 | 0.0597 | 1 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0011 | 0.0011 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0037 | 0.0023 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.0001 | 0.0001 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0044 | 0.0036 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0932 | 0.1652 | 0.1652 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0037 | 0.0023 | 0.0023 |
Onchocerca volvulus | 0.0932 | 0.1652 | 1 | |
Toxoplasma gondii | fructose-bisphospatase I | 0.0131 | 0.0194 | 0.2722 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0207 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | ecdysteroid receptor | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0088 | 0.0115 | 0.0115 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0037 | 0.0023 | 0.0023 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0932 | 0.1652 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0037 | 0.0023 | 0.0023 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.0302 | 0.0302 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0037 | 0.0023 | 0.0023 |
Brugia malayi | nuclear receptor NHR-88 | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0352 | 0.0597 | 0.0597 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0932 | 0.1652 | 0.1652 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0179 | 0.0281 | 0.1335 |
Echinococcus multilocularis | geminin | 0.0191 | 0.0302 | 0.0302 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0352 | 0.0597 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.5516 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0025 | 0.0001 | 0.0001 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | lamin | 0.0031 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | acetylcholinesterase | 0.5516 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0011 | 0.0011 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.0063 | 0.007 | 0.5 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0048 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0011 | 0.0011 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0025 | 0.0001 | 0.0001 |
Echinococcus granulosus | neuroligin | 0.0932 | 0.1652 | 0.1652 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0037 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | carboxylesterase | 0.0932 | 0.1652 | 0.1652 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0058 | 0.0061 | 0.0343 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0062 | 0.0069 | 0.0069 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0088 | 0.0115 | 0.0115 |
Onchocerca volvulus | 0.0932 | 0.1652 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | Carboxylesterase family protein | 0.0932 | 0.1652 | 0.1652 |
Echinococcus granulosus | acetylcholinesterase | 0.5516 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0932 | 0.1652 | 0.1652 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0025 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0932 | 0.1652 | 1 | |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0131 | 0.0194 | 0.2733 |
Loa Loa (eye worm) | acetyltransferase | 0.0164 | 0.0254 | 0.0254 |
Echinococcus granulosus | geminin | 0.0191 | 0.0302 | 0.0302 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.034 | 0.0574 | 0.9594 |
Echinococcus granulosus | lamin | 0.0031 | 0.0011 | 0.0011 |
Schistosoma mansoni | coup transcription factor | 0.0025 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0932 | 0.1652 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.008 | 0.0065 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0932 | 0.1652 | 0.1652 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.008 | 0.008 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0352 | 0.0597 | 0.0597 |
Mycobacterium ulcerans | hypothetical protein | 0.0179 | 0.0281 | 0.1335 |
Schistosoma mansoni | gliotactin | 0.0932 | 0.1652 | 0.1652 |
Brugia malayi | nuclear hormone receptor | 0.0025 | 0.0001 | 0.0001 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0932 | 0.1652 | 1 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0131 | 0.0194 | 0.2733 |
Echinococcus granulosus | carboxylesterase 5A | 0.5516 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0025 | 0.0001 | 0.0001 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0025 | 0.0001 | 0.0001 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0011 | 0.0011 |
Schistosoma mansoni | lipoxygenase | 0.0062 | 0.0069 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0025 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0932 | 0.1652 | 0.1652 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0025 | 0.0001 | 0.0001 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | 0 % | Inhibition of LTD4 (leukotrine) induced bronchospasm in the guinea pig when administered perorally (50 mg/kg) | ChEMBL. | 3669017 |
Inhibition (functional) | 0 % | Inhibition of ovalbumin (OA) induced bronchospasm in the guinea pig at 50 mg/kg | ChEMBL. | 3669017 |
Inhibition (functional) | = 20 % | Inhibition of Ovalbumin (OA) induced bronchospasm in the guinea pig when administered intraduodenally (50 mg/kg) | ChEMBL. | 3669017 |
Inhibition (functional) | = 20 % | Inhibition of Ovalbumin (OA) induced bronchospasm in the guinea pig when administered intraduodenally (50 mg/kg) | ChEMBL. | 3669017 |
Inhibition (functional) | = 71 % | Inhibition of LTD4 (leukotrine) induced bronchospasm in the guinea pig when administered intraduodenally (50 mg/kg) | ChEMBL. | 3669017 |
Inhibition (functional) | = 71 % | Inhibition of LTD4 (leukotrine) induced bronchospasm in the guinea pig when administered intraduodenally (50 mg/kg) | ChEMBL. | 3669017 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.