Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.0204 | 0.0528 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.014 | 0.0582 | 0.0575 |
Toxoplasma gondii | cathepsin CPL | 0.014 | 0.0582 | 0.2957 |
Onchocerca volvulus | 0.0098 | 0.0285 | 0.2989 | |
Toxoplasma gondii | cathepsin B | 0.0338 | 0.1968 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.014 | 0.0582 | 0.0575 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0354 | 0.2073 | 0.5538 |
Brugia malayi | Papain family cysteine protease containing protein | 0.014 | 0.0582 | 0.0599 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0103 | 0.0325 | 0.0882 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0325 | 0.0331 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0191 | 0.0938 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.014 | 0.0582 | 0.0599 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0325 | 0.0331 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Entamoeba histolytica | cysteine proteinase, putative | 0.014 | 0.0582 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0777 | 0.5032 | 0.5028 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Brugia malayi | follicle stimulating hormone receptor | 0.143 | 0.96 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Echinococcus granulosus | cathepsin l1 | 0.014 | 0.0582 | 0.0575 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0103 | 0.0325 | 0.0681 |
Loa Loa (eye worm) | ctsf protein | 0.014 | 0.0582 | 0.0599 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.014 | 0.0582 | 0.1639 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0338 | 0.1968 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Schistosoma mansoni | lipoxygenase | 0.0409 | 0.2462 | 0.2456 |
Onchocerca volvulus | Cathepsin L homolog | 0.014 | 0.0582 | 0.6176 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0114 | 0.0398 | 0.1098 |
Schistosoma mansoni | polycystin 1-related | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0396 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.2613 | 0.2716 |
Onchocerca volvulus | 0.0098 | 0.0285 | 0.2989 | |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1487 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1487 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Brugia malayi | Cathepsin L-like precursor | 0.0103 | 0.0325 | 0.0331 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.014 | 0.0582 | 0.0575 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0086 | 0.0204 | 0.0206 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0086 | 0.0204 | 0.0197 |
Brugia malayi | jmjC domain containing protein | 0.0159 | 0.0713 | 0.0735 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0167 | 0.0771 | 0.1761 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0338 | 0.1968 | 0.1962 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0547 | 0.3423 | 0.3561 |
Entamoeba histolytica | cysteine proteinase, putative | 0.014 | 0.0582 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1968 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.101 | 0.4567 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0114 | 0.0398 | 0.0407 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0291 | 0.1638 | 0.17 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.014 | 0.0582 | 0.0575 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0114 | 0.0396 | 0.0389 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Echinococcus granulosus | cysteine protease | 0.0086 | 0.0204 | 0.0197 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0431 | 0.2613 | 0.7615 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0325 | 0.0331 |
Schistosoma mansoni | jumonji domain containing protein | 0.0206 | 0.1045 | 0.1038 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.023 | 0.0232 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.014 | 0.0582 | 0.0599 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0086 | 0.0204 | 0.0197 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0086 | 0.0204 | 0.0197 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0103 | 0.0325 | 0.0318 |
Plasmodium vivax | vivapain-2 | 0.014 | 0.0582 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0135 | 0.0543 | 0.0558 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0103 | 0.0325 | 0.0331 |
Onchocerca volvulus | Cathepsin L homolog | 0.014 | 0.0582 | 0.6176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.014 | 0.0582 | 0.0575 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0159 | 0.0713 | 0.0706 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Plasmodium vivax | vivapain-2 | 0.014 | 0.0582 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Echinococcus multilocularis | cysteine protease | 0.014 | 0.0582 | 0.0575 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Schistosoma mansoni | rab6-interacting | 0.0098 | 0.0285 | 0.0278 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0186 | 0.0903 | 0.5 |
Echinococcus granulosus | RUN | 0.0098 | 0.0285 | 0.0278 |
Onchocerca volvulus | Cathepsin F homolog | 0.014 | 0.0582 | 0.6176 |
Brugia malayi | Cathepsin L-like precursor | 0.0103 | 0.0325 | 0.0331 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0338 | 0.1968 | 0.5717 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.101 | 0.4567 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0338 | 0.1968 | 0.5189 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0354 | 0.2073 | 0.6028 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.014 | 0.0582 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0167 | 0.0771 | 0.1234 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0114 | 0.0398 | 0.1098 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0354 | 0.2073 | 0.5806 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Schistosoma mansoni | loxhd1 | 0.0098 | 0.0285 | 0.0278 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0098 | 0.0285 | 0.0278 |
Loa Loa (eye worm) | cysteine protease | 0.014 | 0.0582 | 0.0599 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0086 | 0.0204 | 0.0528 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1968 | 0.5 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Loa Loa (eye worm) | doublecortin family protein | 0.0098 | 0.0285 | 0.029 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0103 | 0.0325 | 0.0681 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0354 | 0.2073 | 0.6028 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Echinococcus granulosus | tumor protein p63 | 0.0777 | 0.5032 | 0.5028 |
Echinococcus multilocularis | RUN | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0086 | 0.0204 | 0.0197 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.014 | 0.0582 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0103 | 0.0325 | 0.0331 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Echinococcus multilocularis | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Brugia malayi | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Mycobacterium ulcerans | hypothetical protein | 0.0186 | 0.0903 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0159 | 0.0713 | 0.0706 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.0094 | 0.0091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0098 | 0.0285 | 0.2144 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Brugia malayi | jmjC domain containing protein | 0.0229 | 0.1205 | 0.1249 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0159 | 0.0713 | 0.0735 |
Echinococcus multilocularis | cysteine protease | 0.014 | 0.0582 | 0.0575 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.014 | 0.0582 | 0.0575 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0585 | 0.3693 | 0.3688 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.143 | 0.96 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Onchocerca volvulus | 0.0103 | 0.0325 | 0.341 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0135 | 0.0543 | 0.0558 |
Trypanosoma brucei | cytochrome P450, putative | 0.0114 | 0.0398 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 0.3423 | 0.3561 |
Echinococcus granulosus | cathepsin L | 0.0086 | 0.0204 | 0.0197 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1968 | 0.5 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0431 | 0.2613 | 0.2716 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.014 | 0.0582 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 0.0913 | 0.0945 |
Loa Loa (eye worm) | fibroinase | 0.014 | 0.0582 | 0.0599 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0086 | 0.0204 | 0.0528 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0585 | 0.3693 | 0.3688 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0086 | 0.0204 | 0.0528 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Schistosoma mansoni | lipoxygenase | 0.0585 | 0.3693 | 0.3688 |
Loa Loa (eye worm) | cathepsin B | 0.0338 | 0.1968 | 0.2044 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0338 | 0.1968 | 0.5478 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0167 | 0.0771 | 0.2196 |
Brugia malayi | Doublecortin family protein | 0.0098 | 0.0285 | 0.029 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0098 | 0.0285 | 0.2144 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0169 | 0.0169 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0135 | 0.0543 | 0.0558 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0229 | 0.1205 | 0.1199 |
Leishmania major | cysteine peptidase A (CPA) | 0.014 | 0.0582 | 0.0608 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0291 | 0.1638 | 0.17 |
Echinococcus granulosus | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.014 | 0.0582 | 0.0575 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Entamoeba histolytica | cysteine protease, putative | 0.014 | 0.0582 | 1 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0547 | 0.3423 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Echinococcus granulosus | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Brugia malayi | Cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0159 | 0.0713 | 0.0706 |
Trypanosoma cruzi | cysteine protease, putative | 0.0086 | 0.0204 | 0.0528 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0086 | 0.0204 | 0.0206 |
Brugia malayi | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0159 | 0.0713 | 0.0706 |
Echinococcus multilocularis | cathepsin L | 0.0086 | 0.0204 | 0.0197 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0547 | 0.3423 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.014 | 0.0582 | 0.0575 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0582 | 0.0599 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0229 | 0.1205 | 0.1199 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Onchocerca volvulus | 0.0114 | 0.0396 | 0.418 | |
Brugia malayi | Cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0103 | 0.0325 | 0.3182 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0285 | 0.0278 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Schistosoma mansoni | rab6-interacting | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0547 | 0.3423 | 1 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Echinococcus granulosus | cathepsin l1 | 0.0103 | 0.0325 | 0.0318 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.006 mg kg-1 | Ability to antagonize the stereotypy in rats induced by d-amphetamine sulfate 5 h later of the treatment | ChEMBL. | 2876105 |
ED50 (functional) | = 0.02 mg kg-1 | Ability to antagonize the stereotypy in rats induced by d-amphetamine sulfate 1 h later of the treatment | ChEMBL. | 2876105 |
ED50 (functional) | = 0.66 mg kg-1 | Ability to antagonize the stereotypy in rats induced by d-amphetamine sulfate 24 h later of the treatment | ChEMBL. | 2876105 |
IC50 (binding) | = 15 nM | Ability to displace [3H]-spiroperidol from labeled Dopamine receptor of corpus striatum | ChEMBL. | 2876105 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.