Detailed information for compound 1114374

Basic information

Technical information
  • TDR Targets ID: 1114374
  • Name: 4-(3-piperidin-1-ylpropyl)-6-[3-(trifluoromet hyl)phenyl]pyrimidine-2-carbonitrile
  • MW: 374.403 | Formula: C20H21F3N4
  • H donors: 0 H acceptors: 3 LogP: 4.34 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1nc(CCCN2CCCCC2)cc(n1)c1cccc(c1)C(F)(F)F
  • InChi: 1S/C20H21F3N4/c21-20(22,23)16-7-4-6-15(12-16)18-13-17(25-19(14-24)26-18)8-5-11-27-9-2-1-3-10-27/h4,6-7,12-13H,1-3,5,8-11H2
  • InChiKey: XGXDWBUGQKHTSH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-[3-(1-piperidyl)propyl]-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile
  • 4-[3-(1-piperidyl)propyl]-6-[3-(trifluoromethyl)phenyl]-2-pyrimidinecarbonitrile
  • 4-(3-piperidinopropyl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cathepsin S Starlite/ChEMBL References
Homo sapiens cathepsin K Starlite/ChEMBL References
Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 2 Starlite/ChEMBL References
Homo sapiens cathepsin L Starlite/ChEMBL References
Homo sapiens cathepsin B Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis voltage and ligand gated potassium channel, putative Get druggable targets OG5_128858 All targets in OG5_128858
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative Get druggable targets OG5_128858 All targets in OG5_128858
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis potassium voltage gated channel subfamily H Get druggable targets OG5_128858 All targets in OG5_128858
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni SmCB2 peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase C (CPC), putative,CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like, putative Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01363 cathepsin B [EC3.4.22.1], putative Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase C (CPC), putative Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin B-like cysteine proteinase Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin B-like protease (Precursor), related Get druggable targets OG5_127800 All targets in OG5_127800
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Giardia lamblia Cathepsin B precursor Get druggable targets OG5_127800 All targets in OG5_127800
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin b Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Toxoplasma gondii cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative Get druggable targets OG5_128858 All targets in OG5_128858
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128858 All targets in OG5_128858
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) voltage and ligand gated potassium channel Get druggable targets OG5_128858 All targets in OG5_128858
Schistosoma japonicum Potassium voltage-gated channel subfamily H member 2, putative Get druggable targets OG5_128858 All targets in OG5_128858
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus potassium voltage gated channel subfamily H Get druggable targets OG5_128858 All targets in OG5_128858
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Leishmania braziliensis cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cathepsin B Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog Get druggable targets OG5_128858 All targets in OG5_128858
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin B-like cysteine proteinase precursor, putative Get druggable targets OG5_127800 All targets in OG5_127800
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like Get druggable targets OG5_127800 All targets in OG5_127800
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis voltage and ligand gated potassium channel, putative Get druggable targets OG5_128858 All targets in OG5_128858
Trypanosoma congolense cysteine peptidase C (CPC) Get druggable targets OG5_127800 All targets in OG5_127800
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum dipeptidyl aminopeptidase 1 cathepsin B 339 aa 368 aa 26.9 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin L 333 aa 359 aa 30.1 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin S 281 aa 226 aa 34.1 %
Plasmodium falciparum cysteine proteinase falcipain 1 cathepsin K 329 aa 349 aa 33.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0027 0.0425 0.0425
Brugia malayi Cathepsin L-like precursor 0.0059 0.2438 0.2438
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Onchocerca volvulus 0.0086 0.41 1
Echinococcus granulosus cathepsin l1 0.0086 0.41 0.41
Trypanosoma cruzi cruzipain precursor, putative 0.0086 0.41 0.41
Echinococcus multilocularis cathepsin L cysteine protease 0.0086 0.41 0.41
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0047 0.1662 0.1662
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.1662 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.007 0.3093 0.3093
Entamoeba histolytica cysteine proteinase 2 0.0047 0.1662 0.4054
Echinococcus granulosus cathepsin b 0.0181 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0047 0.1662 0.1662
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Echinococcus multilocularis cathepsin b 0.0181 1 1
Echinococcus multilocularis cathepsin b 0.0181 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0086 0.41 0.41
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Plasmodium vivax unspecified product 0.0027 0.0425 0.1037
Onchocerca volvulus 0.0059 0.2438 0.5946
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.135 0.3292
Trypanosoma cruzi cysteine protease, putative 0.0047 0.1662 0.1662
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Echinococcus granulosus cathepsin l cysteine peptidase 0.0086 0.41 0.41
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Onchocerca volvulus Cathepsin F homolog 0.0086 0.41 1
Toxoplasma gondii cathepsin B 0.007 0.3093 0.7543
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.41 0.41
Plasmodium vivax unspecified product 0.0047 0.1662 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Entamoeba histolytica cysteine proteinase, putative 0.0059 0.2438 0.5946
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Onchocerca volvulus 0.0086 0.41 1
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.41 0.41
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.1786 0.1786
Brugia malayi Cathepsin L-like precursor 0.0027 0.0425 0.0425
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0027 0.0425 0.0425
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0086 0.41 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0086 0.41 0.41
Echinococcus multilocularis cysteine protease 0.0086 0.41 0.41
Plasmodium falciparum cysteine proteinase falcipain 3 0.0086 0.41 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0047 0.1662 0.4054
Brugia malayi Cathepsin L-like precursor 0.0086 0.41 0.41
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0086 0.41 0.41
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.41 0.41
Onchocerca volvulus 0.0086 0.41 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Toxoplasma gondii cathepsin CPL 0.0086 0.41 1
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.1662 0.4054
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Entamoeba histolytica cysteine protease, putative 0.0086 0.41 1
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.41 0.41
Loa Loa (eye worm) hypothetical protein 0.0059 0.2438 0.2438
Brugia malayi Cathepsin L-like precursor 0.0059 0.2438 0.2438
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.41 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0425 0.0425
Brugia malayi Cathepsin L-like precursor 0.0086 0.41 0.41
Loa Loa (eye worm) hypothetical protein 0.0059 0.2438 0.2438
Onchocerca volvulus 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Echinococcus multilocularis cysteine protease 0.0086 0.41 0.41
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.2438 0.5946
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.135 0.3292
Echinococcus granulosus cysteine protease 0.0047 0.1662 0.1662
Brugia malayi Cathepsin L-like cysteine proteinase 0.0059 0.2438 0.2438
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0027 0.0425 0.0425
Entamoeba histolytica cysteine proteinase, putative 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.41 0.41
Loa Loa (eye worm) fibroinase 0.0086 0.41 0.41
Loa Loa (eye worm) cathepsin B 0.007 0.3093 0.3093
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0047 0.1662 0.1662
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0045 0.1532 0.1532
Trypanosoma cruzi cysteine peptidase, putative 0.0086 0.41 0.41
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0086 0.41 1
Schistosoma mansoni cathepsin F (C01 family) 0.0059 0.2438 0.2438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Plasmodium vivax vivapain-1 0.0047 0.1662 0.4054
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.1532 0.1532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Trypanosoma cruzi cruzipain precursor, putative 0.0027 0.0425 0.0425
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0181 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.1662 0.4054
Echinococcus granulosus cathepsin b 0.0181 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0047 0.1662 0.1662
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Trypanosoma cruzi cysteine proteinase, putative 0.0047 0.1662 0.1662
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0181 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.1166 0.1166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.2438 0.5946
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Loa Loa (eye worm) cysteine protease 0.0086 0.41 0.41
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Onchocerca volvulus 0.0086 0.41 1
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Giardia lamblia Cathepsin B precursor 0.007 0.3093 1
Loa Loa (eye worm) hypothetical protein 0.0181 1 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0086 0.41 0.41
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Plasmodium vivax vivapain-2 0.0086 0.41 1
Brugia malayi Papain family cysteine protease containing protein 0.0086 0.41 0.41
Onchocerca volvulus Cathepsin L homolog 0.0086 0.41 1
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Loa Loa (eye worm) ctsf protein 0.0086 0.41 0.41
Entamoeba histolytica cysteine proteinase 1, putative 0.0047 0.1662 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.007 0.3093 0.7543
Onchocerca volvulus 0.0086 0.41 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.007 0.3093 0.5868
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.1662 0.4054
Echinococcus multilocularis cathepsin L cysteine protease 0.0086 0.41 0.41
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Echinococcus multilocularis cathepsin L 0.0047 0.1662 0.1662
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.1662 0.1662
Giardia lamblia Cathepsin B precursor 0.007 0.3093 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Trypanosoma cruzi cysteine proteinase, putative 0.0047 0.1662 0.1662
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.2438 0.2438
Giardia lamblia Cathepsin B precursor 0.007 0.3093 1
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0425 0.0425
Brugia malayi Cathepsin L-like precursor 0.0086 0.41 0.41
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0027 0.0425 0.0425
Plasmodium vivax vivapain-2 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Brugia malayi Papain family cysteine protease containing protein 0.0047 0.1662 0.1662
Leishmania major cysteine peptidase A (CPA) 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Onchocerca volvulus Cathepsin L homolog 0.0086 0.41 1
Echinococcus granulosus cathepsin L cysteine protease 0.0047 0.1662 0.1662
Schistosoma mansoni cathepsin s 0.0027 0.0425 0.0425
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.1532 0.1532
Loa Loa (eye worm) hypothetical protein 0.0059 0.2438 0.2438
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.1662 0.4054
Onchocerca volvulus 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0086 0.41 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0045 0.1532 0.1532
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Leishmania major cathepsin L-like protease 0.0086 0.41 1
Brugia malayi Cathepsin L-like precursor 0.0086 0.41 0.41
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Brugia malayi Papain family cysteine protease containing protein 0.0047 0.1662 0.1662
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0181 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.1662 0.4054
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0086 0.41 0.41
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.1786 0.1786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Echinococcus granulosus cathepsin L 0.0047 0.1662 0.1662
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0086 0.41 1
Entamoeba histolytica cysteine protease, putative 0.0047 0.1662 0.4054
Echinococcus granulosus cathepsin l1 0.0059 0.2438 0.2438
Brugia malayi cathepsin L-like precursor 0.0059 0.2438 0.2438
Schistosoma mansoni cathepsin F (C01 family) 0.0086 0.41 0.41
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0086 0.41 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0086 0.41 1
Plasmodium vivax vivapain-3 0.0047 0.1662 0.4054
Loa Loa (eye worm) hypothetical protein 0.0086 0.41 0.41
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.007 0.3093 0.3093
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0086 0.41 0.41

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 4 nM Inhibition of human recombinant cathepsin K by fluorescence assay ChEMBL. 20149657
IC50 (binding) = 4 nM Inhibition of human recombinant cathepsin K using Z-Phe-Arg-MCA substrate by fluorimetric assay ChEMBL. 20843687
IC50 (binding) = 23 nM Inhibition of human recombinant cathepsin S by fluorescence assay ChEMBL. 20149657
IC50 (binding) = 4200 nM Inhibition of human recombinant cathepsin B by fluorescence assay ChEMBL. 20149657
IC50 (binding) > 10000 nM Inhibition of human recombinant cathepsin L by fluorescence assay ChEMBL. 20149657
IC50 (binding) = 0.16 uM Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells ChEMBL. 20149657
Ki (binding) = 0.16 uM Displacement of [3H] dofetilide from human ERG channel expressed in HEK293 cells ChEMBL. 20843687

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.