Detailed information for compound 1148223

Basic information

Technical information
  • TDR Targets ID: 1148223
  • Name: 6,7,8,9-tetrahydropyrido[2,1-b]quinazolin-11- one
  • MW: 200.236 | Formula: C12H12N2O
  • H donors: 0 H acceptors: 1 LogP: 1.3 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=c1c2ccccc2nc2n1CCCC2
  • InChi: 1S/C12H12N2O/c15-12-9-5-1-2-6-10(9)13-11-7-3-4-8-14(11)12/h1-2,5-6H,3-4,7-8H2
  • InChiKey: LMDWOGWJYVSXEP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • ZINC00518786
  • STK099926
  • 11H-Pyrido[2,1-b]quinazolin-11-one, 6,7,8,9-tetrahydro

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae Probable lipase LipE 0.0041 0.0759 0.6987
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1057 0.7515
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0322 0.193
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.3015 1
Mycobacterium tuberculosis Conserved protein 0.0041 0.0759 0.1119
Mycobacterium ulcerans hypothetical protein 0.0053 0.1057 0.7515
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0703 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.2307 0.7652
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.1639 0.2938
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0626 0.1103
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0053 0.1057 0.7515
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0114 0.268 0.268
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0322 0.193
Echinococcus multilocularis GPCR, family 2 0.0017 0.0106 0.0106
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Onchocerca volvulus 0.0253 0.6394 1
Onchocerca volvulus 0.0041 0.0759 0.1092
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0126 0.3015 0.5406
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0759 0.1119
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0053 0.1057 0.1895
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.1057 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1384 1
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.1171 0.3884
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0506 0.3328
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0703 0.1035
Leishmania major hypothetical protein, conserved 0.0041 0.0759 0.5251
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1057 0.1877
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0759 0.1361
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0053 0.1057 0.7515
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0068 0.0085
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.2307 0.2307
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0759 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1384 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0106 0.0167
Onchocerca volvulus 0.0053 0.1057 0.1563
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0068 0.0085
Brugia malayi Pre-SET motif family protein 0.0222 0.5577 1
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1057 0.1877
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Loa Loa (eye worm) hypothetical protein 0.0089 0.2022 0.3625
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0068 0.0122
Loa Loa (eye worm) beta-lactamase 0.0041 0.0759 0.1361
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0506 0.0506
Entamoeba histolytica hypothetical protein 0.0025 0.0322 0.2569
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0114 0.268 0.268
Brugia malayi chromobox protein homolog 3 0.0042 0.0768 0.1357
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0852 0.1239
Loa Loa (eye worm) hypothetical protein 0.0015 0.0068 0.0122
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.01 0.2307 0.4137
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0106 0.0106
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0106 0.0167
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0322 0.193
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0443 0.0593
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.1384 0.2053
Toxoplasma gondii ABC1 family protein 0.0041 0.0759 0.5251
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0506 0.1679
Mycobacterium ulcerans lipase LipD 0.0041 0.0759 0.5251
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0759 0.1092
Onchocerca volvulus 0.0041 0.0759 0.1092
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0114 0.268 0.4805
Loa Loa (eye worm) hypothetical protein 0.0053 0.1057 0.1895
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0759 0.1119
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Mycobacterium tuberculosis Conserved protein 0.0041 0.0759 0.1119
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1057 0.7515
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0068 0.0122
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.1057 0.7515
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0759 0.1119
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0322 0.3676
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0322 0.4
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.2307 0.2307
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.2307 0.7652
Mycobacterium ulcerans beta-lactamase 0.0041 0.0759 0.5251
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.1057 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0068 0.0085
Loa Loa (eye worm) hypothetical protein 0.0015 0.0068 0.0122
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0114 0.268 0.4794
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0768 0.1106
Mycobacterium ulcerans hypothetical protein 0.0041 0.0759 0.5251
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0759 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.2022 0.2022
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1384 0.4591
Schistosoma mansoni hypothetical protein 0.0036 0.0626 0.2077
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0759 0.2518
Loa Loa (eye worm) hypothetical protein 0.0057 0.1171 0.21
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.083 0.2754
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0852 0.1239
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.1384 1
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0759 0.1092
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1057 0.7515
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0443 0.0593
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0068 0.0085
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.1057 1
Trichomonas vaginalis esterase, putative 0.0041 0.0759 0.1092
Echinococcus granulosus chromobox protein 1 0.0074 0.1639 0.1639
Schistosoma mansoni chromobox protein 0.0074 0.1639 0.5436
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0126 0.3015 0.5396
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0703 0.4826
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0053 0.1057 0.1564
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0106 0.0189
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0852 0.1239
Echinococcus multilocularis tumor protein p63 0.0389 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.2022 0.3611
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0068 0.0085
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0265 0.6698 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.2307 0.7652
Loa Loa (eye worm) oxidoreductase 0.0015 0.0068 0.0122
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0322 0.5
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0759 0.6987
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0322 0.193
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.1384 0.1384
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0703 1
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.2022 0.2022
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0759 0.5251
Schistosoma mansoni chromobox protein 0.0074 0.1639 0.5436
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0322 0.5
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0759 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.2307 0.2307
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0759 0.1092
Plasmodium vivax SET domain protein, putative 0.0032 0.0506 0.6338
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Trichomonas vaginalis set domain proteins, putative 0.0253 0.6394 1
Mycobacterium tuberculosis Conserved protein 0.0041 0.0759 0.1119
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0759 0.1119
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.5577 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0768 0.1377
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0703 0.919
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0036 0.0626 0.1123
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.01 0.2307 0.4123
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0759 0.1119
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0759 0.1092
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.1384 0.1384
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1057 0.7515
Onchocerca volvulus 0.002 0.0178 0.0174
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0322 0.0465
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0759 0.2518
Onchocerca volvulus 0.0033 0.0528 0.0727
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.2022 0.6706
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0506 0.1679
Echinococcus granulosus chromobox protein 1 0.0074 0.1639 0.1639
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0506 0.1679
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.1057 0.1564
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.1075 0.1928
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0759 0.0759
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0068 0.0085
Onchocerca volvulus 0.0044 0.083 0.1205
Echinococcus multilocularis chromobox protein 1 0.0074 0.1639 0.1639
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.1075 0.1909
Brugia malayi beta-lactamase family protein 0.0041 0.0759 0.1342
Brugia malayi beta-lactamase family protein 0.0041 0.0759 0.1342
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0068 0.0068
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0068 0.0068
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0322 0.2569
Trichomonas vaginalis chromobox protein, putative 0.0074 0.1639 0.2483
Entamoeba histolytica acyl-coA synthetase, putative 0.0053 0.1057 1
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0759 0.1119
Onchocerca volvulus 0.0089 0.2022 0.3088
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1384 0.4591
Loa Loa (eye worm) hypothetical protein 0.0053 0.1075 0.1928
Brugia malayi Heterochromatin protein 1 0.0074 0.1639 0.2922
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0106 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0768 0.1106
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.1057 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0068 0.0085
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0759 0.0759
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1057 0.1877
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0759 0.1092
Loa Loa (eye worm) hypothetical protein 0.0033 0.0528 0.0946
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1384 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.1075 0.1909
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0506 0.0506
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0759 0.5251
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0017 0.0106 0.0189
Loa Loa (eye worm) hypothetical protein 0.0032 0.0506 0.0907
Brugia malayi Pre-SET motif family protein 0.0032 0.0506 0.0887
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0068 0.01
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0068 0.01
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Brugia malayi beta-lactamase 0.0041 0.0759 0.1342
Onchocerca volvulus 0.0057 0.1171 0.1743
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.2307 0.2307
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0322 0.3676
Echinococcus granulosus GPCR family 2 0.0017 0.0106 0.0106
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1057 0.7515
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0759 1
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.1384 1
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0068 0.0226
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0322 0.193
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0759 0.1342
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0759 0.1119
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1057 0.7515
Trichomonas vaginalis chromobox protein, putative 0.0074 0.1639 0.2483
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0768 0.1106
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0114 0.268 0.4805
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0053 0.1057 0.7515
Echinococcus multilocularis chromobox protein 1 0.0074 0.1639 0.1639
Onchocerca volvulus 0.0041 0.0759 0.1092
Loa Loa (eye worm) hypothetical protein 0.0053 0.1057 0.1895

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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