Detailed information for compound 1148223

Basic information

Technical information
  • TDR Targets ID: 1148223
  • Name: 6,7,8,9-tetrahydropyrido[2,1-b]quinazolin-11- one
  • MW: 200.236 | Formula: C12H12N2O
  • H donors: 0 H acceptors: 1 LogP: 1.3 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=c1c2ccccc2nc2n1CCCC2
  • InChi: 1S/C12H12N2O/c15-12-9-5-1-2-6-10(9)13-11-7-3-4-8-14(11)12/h1-2,5-6H,3-4,7-8H2
  • InChiKey: LMDWOGWJYVSXEP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • ZINC00518786
  • STK099926
  • 11H-Pyrido[2,1-b]quinazolin-11-one, 6,7,8,9-tetrahydro

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0759 0.1092
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.1384 0.1384
Mycobacterium ulcerans lipase LipD 0.0041 0.0759 0.5251
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.2307 0.7652
Loa Loa (eye worm) hypothetical protein 0.0017 0.0106 0.0189
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1057 0.7515
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1057 0.7515
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0759 0.1119
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.2307 0.2307
Entamoeba histolytica hypothetical protein 0.0025 0.0322 0.2569
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0322 0.0465
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0759 0.1119
Loa Loa (eye worm) hypothetical protein 0.0033 0.0528 0.0946
Echinococcus multilocularis GPCR, family 2 0.0017 0.0106 0.0106
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0759 0.1092
Loa Loa (eye worm) hypothetical protein 0.0032 0.0506 0.0907
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1057 0.7515
Plasmodium vivax SET domain protein, putative 0.0032 0.0506 0.6338
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.1057 0.1564
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0443 0.0593
Mycobacterium ulcerans beta-lactamase 0.0041 0.0759 0.5251
Trichomonas vaginalis esterase, putative 0.0041 0.0759 0.1092
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0759 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0759 0.1119
Mycobacterium leprae Probable lipase LipE 0.0041 0.0759 0.6987
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0852 0.1239
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0265 0.6698 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0759 0.2518
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.2307 0.2307
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.1171 0.3884
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0106 0.0106
Mycobacterium tuberculosis Conserved protein 0.0041 0.0759 0.1119
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.1057 1
Echinococcus granulosus chromobox protein 1 0.0074 0.1639 0.1639
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1057 0.7515
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1057 0.1877
Loa Loa (eye worm) hypothetical protein 0.0053 0.1057 0.1895
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1057 0.1877
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0114 0.268 0.268
Loa Loa (eye worm) hypothetical protein 0.0053 0.1075 0.1928
Echinococcus granulosus chromobox protein 1 0.0074 0.1639 0.1639
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0759 0.1119
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0322 0.193
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0114 0.268 0.4805
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0322 0.5
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0322 0.193
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.083 0.2754
Onchocerca volvulus 0.0057 0.1171 0.1743
Brugia malayi beta-lactamase 0.0041 0.0759 0.1342
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Brugia malayi beta-lactamase family protein 0.0041 0.0759 0.1342
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0759 0.1092
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0852 0.1239
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.3015 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1384 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0852 0.1239
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.1075 0.1928
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1384 1
Echinococcus multilocularis chromobox protein 1 0.0074 0.1639 0.1639
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0114 0.268 0.4794
Onchocerca volvulus 0.0041 0.0759 0.1092
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.1057 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0068 0.0068
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0053 0.1057 0.7515
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0759 0.1119
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0506 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0768 0.1106
Leishmania major hypothetical protein, conserved 0.0041 0.0759 0.5251
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0768 0.1106
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Loa Loa (eye worm) hypothetical protein 0.0036 0.0626 0.1123
Brugia malayi Pre-SET motif family protein 0.0032 0.0506 0.0887
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0506 0.1679
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.1057 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.2022 0.3625
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Loa Loa (eye worm) beta-lactamase 0.0041 0.0759 0.1361
Onchocerca volvulus 0.0033 0.0528 0.0727
Mycobacterium ulcerans hypothetical protein 0.0041 0.0759 0.5251
Brugia malayi chromobox protein homolog 3 0.0042 0.0768 0.1357
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0068 0.01
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0068 0.0085
Toxoplasma gondii ABC1 family protein 0.0041 0.0759 0.5251
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0322 0.4
Loa Loa (eye worm) hypothetical protein 0.0053 0.1057 0.1895
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.5577 1
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Echinococcus multilocularis chromobox protein 1 0.0074 0.1639 0.1639
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0506 0.1679
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0506 0.1679
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0114 0.268 0.4805
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1057 0.7515
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0703 0.1035
Trichomonas vaginalis chromobox protein, putative 0.0074 0.1639 0.2483
Trichomonas vaginalis set domain proteins, putative 0.0253 0.6394 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0068 0.0085
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.1384 0.2053
Schistosoma mansoni chromobox protein 0.0074 0.1639 0.5436
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0759 0.0759
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0759 0.1092
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.2307 0.7652
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0106 0.0106
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0068 0.0085
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0053 0.1057 0.7515
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0106 0.0106
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0703 0.4826
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0322 0.3676
Onchocerca volvulus 0.0041 0.0759 0.1092
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.2022 0.2022
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0068 0.0085
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0759 0.5251
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1057 0.7515
Loa Loa (eye worm) hypothetical protein 0.0015 0.0068 0.0122
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.01 0.2307 0.4123
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.2022 0.6706
Brugia malayi Heterochromatin protein 1 0.0074 0.1639 0.2922
Mycobacterium tuberculosis Conserved protein 0.0041 0.0759 0.1119
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0042 0.0768 0.1377
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1384 0.4591
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0626 0.1103
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0126 0.3015 0.5406
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0322 0.2569
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0068 0.01
Brugia malayi Pre-SET motif family protein 0.0222 0.5577 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1384 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0068 0.0085
Onchocerca volvulus 0.0253 0.6394 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0068 0.0122
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0506 0.0506
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0068 0.0226
Echinococcus multilocularis tumor protein p63 0.0389 1 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.1384 1
Brugia malayi beta-lactamase family protein 0.0041 0.0759 0.1342
Onchocerca volvulus 0.002 0.0178 0.0174
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0114 0.268 0.268
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0106 0.0189
Onchocerca volvulus 0.0041 0.0759 0.1092
Mycobacterium tuberculosis Conserved protein 0.0041 0.0759 0.1119
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0759 0.0759
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0053 0.1057 0.1564
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0759 1
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0759 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0703 0.919
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0053 0.1057 0.7515
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0068 0.0085
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0759 0.2518
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.1639 0.2938
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0759 0.1342
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.2022 0.3611
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.1075 0.1909
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0475 0.0475
Trichomonas vaginalis chromobox protein, putative 0.0074 0.1639 0.2483
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.1384 0.1384
Echinococcus granulosus GPCR family 2 0.0017 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0041 0.0759 0.1361
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0322 0.193
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0126 0.3015 0.5396
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.2307 0.2307
Onchocerca volvulus 0.0044 0.083 0.1205
Onchocerca volvulus 0.0053 0.1057 0.1563
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0759 0.5251
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Loa Loa (eye worm) hypothetical protein 0.0057 0.1171 0.21
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0759 0.1119
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0768 0.1106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.2307 0.2307
Loa Loa (eye worm) hypothetical protein 0.0039 0.0703 0.1261
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0759 0.1361
Schistosoma mansoni chromobox protein 0.0074 0.1639 0.5436
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0506 0.0506
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0106 0.0167
Loa Loa (eye worm) oxidoreductase 0.0015 0.0068 0.0122
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0322 0.193
Schistosoma mansoni hypothetical protein 0.0017 0.0106 0.035
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0759 0.6987
Entamoeba histolytica acyl-coA synthetase, putative 0.0053 0.1057 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0322 0.5
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0703 1
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1384 0.4591
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0068 0.0122
Loa Loa (eye worm) hypothetical protein 0.0015 0.0068 0.0122
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0322 0.193
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0759 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0068 0.0085
Schistosoma mansoni hypothetical protein 0.0036 0.0626 0.2077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.2307 0.7652
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0506 0.3328
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0322 0.3676
Loa Loa (eye worm) hypothetical protein 0.0053 0.1057 0.1895
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0759 0.1092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0068 0.01
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.1057 1
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0106 0.0167
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0068 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0443 0.0593
Mycobacterium ulcerans hypothetical protein 0.0053 0.1057 0.7515
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0646 0.095
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.01 0.2307 0.4137
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0759 0.1119
Onchocerca volvulus 0.0089 0.2022 0.3088
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.1384 1
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0703 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.1057 0.7515
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1057 0.1877
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.1075 0.1909
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.2022 0.2022

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.