Detailed information for compound 1172606

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 281.304 | Formula: C14H19NO5
  • H donors: 2 H acceptors: 4 LogP: 0.12 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CO[C@]12CCCCC1=C(N1[C@H]2[C@@H]([C@H](O)C)C1=O)C(=O)O
  • InChi: 1S/C14H19NO5/c1-7(16)9-11-14(20-2)6-4-3-5-8(14)10(13(18)19)15(11)12(9)17/h7,9,11,16H,3-6H2,1-2H3,(H,18,19)/t7-,9-,11+,14-/m1/s1
  • InChiKey: MPNGECKWGYUVMF-CZVPAOTRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi chromobox protein homolog 3 0.0046 0.0295 0.0552
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0151 0.0134
Loa Loa (eye worm) hypothetical protein 0.008 0.0831 0.0831
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0045 0.0278 0.5
Schistosoma mansoni ran 0.0046 0.0295 0.0146
Onchocerca volvulus 0.0058 0.0489 0.0872
Schistosoma mansoni lamin 0.0058 0.0489 0.0344
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0151 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Onchocerca volvulus 0.0037 0.0151 0.0027
Plasmodium vivax importin-beta 2, putative 0.0062 0.0552 0.1187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0151 0.0246
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0045 0.0278 0.5
Loa Loa (eye worm) heterochromatin protein 1 0.0082 0.0859 0.0859
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Entamoeba histolytica hypothetical protein 0.0043 0.0255 0.482
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Entamoeba histolytica hypothetical protein 0.0043 0.0255 0.482
Onchocerca volvulus 0.0037 0.0151 0.0027
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.3229 0.3217
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.044 0.0424
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0368 0.1059
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0045 0.0278 0.0374
Entamoeba histolytica hypothetical protein 0.0043 0.0255 0.482
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0062 0.0552 0.0552
Schistosoma mansoni hypothetical protein 0.0037 0.0157 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.0295 0.055
Echinococcus multilocularis GPCR, family 2 0.0037 0.0157 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.044 0.0293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Trichomonas vaginalis rotamase, putative 0.0038 0.0177 0.0343
Trichomonas vaginalis rotamase, putative 0.0039 0.0191 0.0397
Echinococcus granulosus cathepsin L cysteine proteinase 0.0037 0.0151 0.0134
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0151 0.0151
Schistosoma mansoni intermediate filament proteins 0.0058 0.0489 0.0344
Trypanosoma brucei fatty acid desaturase, putative 0.0252 0.3536 1
Onchocerca volvulus 0.0058 0.0489 0.0872
Onchocerca volvulus Huntingtin homolog 0.0291 0.4146 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.044 0.0293
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0217 0.2981 0.297
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0065 0.0065
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0117 0.1412 0.1412
Loa Loa (eye worm) hypothetical protein 0.0291 0.4146 0.4146
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0151 0.0134
Schistosoma mansoni rotamase 0.0039 0.0191 0.0041
Trypanosoma cruzi importin beta-1 subunit, putative 0.005 0.0368 0.0641
Trypanosoma cruzi cruzipain precursor, putative 0.0139 0.1766 0.4772
Schistosoma mansoni hypothetical protein 0.0043 0.0255 0.0106
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0039 0.0191 0.0191
Onchocerca volvulus Huntingtin homolog 0.0291 0.4146 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0046 0.0295 0.0425
Brugia malayi Cathepsin L-like precursor 0.0037 0.0151 0.0205
Toxoplasma gondii exonuclease III APE 0.0045 0.0278 0.3155
Brugia malayi Cathepsin L-like precursor 0.0037 0.0151 0.0205
Brugia malayi hypothetical protein 0.0291 0.4146 0.9782
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.0295 0.0278
Toxoplasma gondii peptidylprolyl isomerase 0.0038 0.0177 0.0644
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0368 0.1059
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0045 0.0278 0.03
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0045 0.0278 0.0261
Echinococcus granulosus geminin 0.0199 0.2697 0.2685
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.044 0.0424
Schistosoma mansoni survival motor neuron protein 0.0047 0.0321 0.0173
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.0295 0.0351
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Plasmodium vivax stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative 0.0252 0.3536 1
Plasmodium falciparum stearoyl-CoA desaturase 0.0252 0.3536 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Loa Loa (eye worm) hypothetical protein 0.0291 0.4146 0.4146
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0151 0.0027
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0295 0.0425
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0489 0.1016
Leishmania major fatty-acid desaturase, putative 0.0252 0.3536 1
Onchocerca volvulus 0.0037 0.0151 0.0027
Trichomonas vaginalis ap endonuclease, putative 0.0045 0.0278 0.0721
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0045 0.0278 0.0374
Trypanosoma cruzi cysteine peptidase, putative 0.0139 0.1766 0.4772
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0151 0.0246
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0038 0.0177 0.0076
Onchocerca volvulus 0.0037 0.0151 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Treponema pallidum exodeoxyribonuclease (exoA) 0.0045 0.0278 0.5
Entamoeba histolytica hypothetical protein 0.005 0.0368 1
Brugia malayi hypothetical protein 0.0043 0.0255 0.0456
Brugia malayi Cathepsin L-like precursor 0.0037 0.0151 0.0205
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Trichomonas vaginalis chromobox protein, putative 0.0049 0.035 0.0992
Brugia malayi Heterochromatin protein 1 0.0082 0.0859 0.1903
Echinococcus granulosus lamin 0.0058 0.0489 0.0473
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0177 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Schistosoma mansoni lamin 0.0058 0.0489 0.0344
Echinococcus granulosus lamin dm0 0.0058 0.0489 0.0473
Entamoeba histolytica hypothetical protein 0.0043 0.0255 0.482
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0127 0.1576 0.4211
Toxoplasma gondii HEAT repeat-containing protein 0.0062 0.0552 1
Leishmania major importin beta-1 subunit, putative 0.005 0.0368 0.0641
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Trichomonas vaginalis importin beta-1, putative 0.005 0.0368 0.1059
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0157 0.0141
Brugia malayi latrophilin 2 splice variant baaae 0.008 0.0831 0.1836
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0295 0.0388
Onchocerca volvulus 0.0037 0.0151 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0045 0.0278 0.0374
Onchocerca volvulus 0.0047 0.0321 0.0452
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0157 0.0157
Schistosoma mansoni importin beta-1 0.0062 0.0552 0.0408
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0859 0.2901
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0321 0.0613
Echinococcus granulosus expressed protein 0.0039 0.0191 0.0175
Brugia malayi exodeoxyribonuclease III family protein 0.0045 0.0278 0.0509
Loa Loa (eye worm) hypothetical protein 0.0046 0.0295 0.0295
Trichomonas vaginalis ran, putative 0.0046 0.0295 0.0785
Loa Loa (eye worm) hypothetical protein 0.0037 0.0157 0.0157
Schistosoma mansoni chromobox protein 0.0082 0.0859 0.0719
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Onchocerca volvulus 0.0252 0.3536 0.8477
Schistosoma mansoni chromobox protein 0.0082 0.0859 0.0719
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Loa Loa (eye worm) acyl-CoA desaturase 0.0252 0.3536 0.3536
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Echinococcus multilocularis snurportin 1 0.0664 1 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0045 0.0278 0.584
Schistosoma mansoni hypothetical protein 0.0037 0.0157 0.0006
Brugia malayi RNA, U transporter 1 0.0177 0.2353 0.5484
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0045 0.0278 0.0261
Echinococcus multilocularis lamin 0.0058 0.0489 0.0473
Plasmodium falciparum importin beta, putative 0.0062 0.0552 0.1187
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.044 0.0424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Trypanosoma cruzi cysteine peptidase, putative 0.0139 0.1766 0.4772
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0191 0.0397
Echinococcus granulosus GPCR family 2 0.0037 0.0157 0.0141
Echinococcus granulosus neuropeptide s receptor 0.0542 0.8093 0.809
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0151 0.0134
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0151 0.0134
Trypanosoma cruzi fatty acid desaturase, putative 0.0252 0.3536 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0037 0.0151 0.0151
Echinococcus granulosus chromobox protein 1 0.0082 0.0859 0.0844
Trypanosoma cruzi cysteine peptidase, putative 0.0139 0.1766 0.4772
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.044 0.0898
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.0295 0.0425
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0151 0.0205
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0208 0.2843 0.6659
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0045 0.0278 0.0374
Echinococcus multilocularis cysteine protease 0.0037 0.0151 0.0134
Trypanosoma cruzi fatty acid desaturase, putative 0.0252 0.3536 1
Schistosoma mansoni ran 0.0046 0.0295 0.0146
Schistosoma mansoni hypothetical protein 0.0199 0.2697 0.2585
Echinococcus granulosus intermediate filament protein 0.0058 0.0489 0.0473
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.0295 0.0278
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0038 0.0177 0.1192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0295 0.0787
Echinococcus multilocularis chromobox protein 1 0.0082 0.0859 0.0844
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0039 0.0191 0.0302
Loa Loa (eye worm) hypothetical protein 0.0037 0.0151 0.0151
Onchocerca volvulus 0.0037 0.0151 0.0027
Entamoeba histolytica Ran family GTPase 0.0046 0.0295 0.6629
Schistosoma mansoni ap endonuclease 0.0045 0.0278 0.0129
Schistosoma mansoni hypothetical protein 0.008 0.0831 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0295 0.0787
Echinococcus multilocularis cysteine protease 0.0037 0.0151 0.0134
Brugia malayi intermediate filament protein 0.0058 0.0489 0.1016
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0489 0.0489
Loa Loa (eye worm) cysteine protease 0.0037 0.0151 0.0151
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0552 0.1119
Brugia malayi Importin beta-1 subunit 0.0062 0.0552 0.1168
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0489 0.0489
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.035 0.0524
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.044 0.0293
Brugia malayi Cathepsin L-like precursor 0.0037 0.0151 0.0205
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.3229 0.3217
Echinococcus granulosus importin subunit beta 1 0.0062 0.0552 0.0537
Echinococcus multilocularis importin subunit beta 1 0.0062 0.0552 0.0537
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0157 0.0141
Leishmania major cathepsin L-like protease 0.0139 0.1766 0.4772
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.0295 0.3581
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0045 0.0278 0.5
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0552 0.1119
Loa Loa (eye worm) hypothetical protein 0.0036 0.014 0.014
Echinococcus multilocularis musashi 0.0058 0.0489 0.0473
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0045 0.0278 0.0278
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0255 0.0106
Brugia malayi Cathepsin L-like precursor 0.0037 0.0151 0.0205
Loa Loa (eye worm) hypothetical protein 0.0233 0.3229 0.3229
Schistosoma mansoni hypothetical protein 0.0037 0.0157 0.0006
Loa Loa (eye worm) fibroinase 0.0037 0.0151 0.0151
Onchocerca volvulus 0.0037 0.0151 0.0027
Loa Loa (eye worm) ctsf protein 0.0037 0.0151 0.0151
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0157 0.022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0046 0.0295 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0255 0.0239
Trichomonas vaginalis chromobox protein, putative 0.0049 0.035 0.0992
Onchocerca volvulus Cathepsin F homolog 0.0037 0.0151 0.0027
Trypanosoma cruzi major cysteine proteinase, putative 0.011 0.1297 0.3387
Echinococcus multilocularis neuropeptide s receptor 0.0542 0.8093 0.809
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0664 1 1
Loa Loa (eye worm) hypothetical protein 0.0297 0.4237 0.4237
Schistosoma mansoni hypothetical protein 0.0037 0.0157 0.0006
Trypanosoma cruzi fatty acid desaturase, putative 0.0252 0.3536 1
Trichomonas vaginalis ap endonuclease, putative 0.0045 0.0278 0.0721
Echinococcus granulosus cathepsin l1 0.0037 0.0151 0.0134
Loa Loa (eye worm) hypothetical protein 0.0057 0.0473 0.0473
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0297 0.4237 1
Brugia malayi Cathepsin L-like precursor 0.0037 0.0151 0.0205
Leishmania major GTP-binding protein, putative 0.0046 0.0295 0.0425
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Loa Loa (eye worm) hypothetical protein 0.0058 0.0489 0.0489
Echinococcus multilocularis geminin 0.0199 0.2697 0.2685
Leishmania major cathepsin L-like protease 0.0139 0.1766 0.4772
Echinococcus multilocularis neuropeptide receptor A26 0.0542 0.8093 0.809
Leishmania major cathepsin L-like protease 0.0139 0.1766 0.4772
Trichomonas vaginalis conserved hypothetical protein 0.0202 0.2753 1
Leishmania major stearic acid desaturase, putative 0.0252 0.3536 1
Schistosoma mansoni hypothetical protein 0.0664 1 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0217 0.2981 0.297
Schistosoma mansoni ap endonuclease 0.0045 0.0278 0.0129
Brugia malayi hypothetical protein 0.0233 0.3229 0.7583
Echinococcus multilocularis expressed protein 0.0039 0.0191 0.0175
Echinococcus granulosus cathepsin l cysteine peptidase 0.0037 0.0151 0.0134
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0038 0.0177 0.0076
Echinococcus multilocularis lamin dm0 0.0058 0.0489 0.0473
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0208 0.2843 0.2843
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.044 0.0424
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0046 0.0295 0.0425
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0157 0.022
Echinococcus granulosus neuropeptide receptor A26 0.0542 0.8093 0.809
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Brugia malayi Calcitonin receptor-like protein seb-1 0.0117 0.1412 0.3229
Echinococcus granulosus chromobox protein 1 0.0082 0.0859 0.0844
Schistosoma mansoni hypothetical protein 0.0047 0.0321 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0151 0.0246
Onchocerca volvulus 0.0252 0.3536 0.8477
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0045 0.0278 0.0374
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0255 0.0239
Echinococcus multilocularis chromobox protein 1 0.0082 0.0859 0.0844
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.0295 0.0295
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0151 0.0246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732
Brugia malayi acyl-CoA desaturase 0.0252 0.3536 0.8319
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0859 0.2901
Schistosoma mansoni hypothetical protein 0.0199 0.2697 0.2585
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0139 0.1766 0.4732

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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