Detailed information for compound 140634

Basic information

Technical information
  • TDR Targets ID: 140634
  • Name: (2S)-1-(4-benzhydrylpiperazin-1-yl)-3-(6-phen ylpurin-3-yl)propan-2-ol
  • MW: 504.625 | Formula: C31H32N6O
  • H donors: 1 H acceptors: 4 LogP: 3.79 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: O[C@H](Cn1cnc(c2c1ncn2)c1ccccc1)CN1CCN(CC1)C(c1ccccc1)c1ccccc1
  • InChi: 1S/C31H32N6O/c38-27(21-37-23-34-28(24-10-4-1-5-11-24)29-31(37)33-22-32-29)20-35-16-18-36(19-17-35)30(25-12-6-2-7-13-25)26-14-8-3-9-15-26/h1-15,22-23,27,30,38H,16-21H2/t27-/m0/s1
  • InChiKey: QFTHCPHICSULPM-MHZLTWQESA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2S)-1-(4-benzhydryl-1-piperazinyl)-3-(6-phenyl-3-purinyl)-2-propanol
  • (2S)-1-(4-benzhydrylpiperazino)-3-(6-phenylpurin-3-yl)propan-2-ol
  • (2S)-1-[4-[di(phenyl)methyl]piperazin-1-yl]-3-(6-phenylpurin-3-yl)propan-2-ol
  • (2S)-1-[4-[di(phenyl)methyl]-1-piperazinyl]-3-(6-phenyl-3-purinyl)propan-2-ol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni netrin receptor unc5 0.0058 0.0179 0.0356
Schistosoma mansoni steroid hormone receptor ad4bp 0.0179 0.1722 0.3538
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0179 0.1722 0.3538
Brugia malayi orphan nuclear receptor NR2E1 0.0084 0.0511 0.074
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Loa Loa (eye worm) steroid hormone receptor 0.0179 0.1722 0.2492
Schistosoma mansoni lipoxygenase 0.0115 0.0907 0.1858
Echinococcus multilocularis ecdysone induced protein 78C 0.0179 0.1722 0.3517
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0179 0.1722 0.3517
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0038 0.0055
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0179 0.1722 0.3538
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0084 0.0511 0.1289
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0179 0.1722 0.2492
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0179 0.1722 0.2492
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0179 0.1722 0.2492
Brugia malayi tailless protein 0.0084 0.0511 0.074
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0084 0.0511 0.1035
Brugia malayi nuclear receptor RXR 0.0095 0.0641 0.0927
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0511 0.1035
Brugia malayi Nuclear hormone receptor E75 0.0084 0.0511 0.074
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0179 0.1722 0.2492
Schistosoma mansoni single-minded 0.0048 0.0043 0.0075
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.1326 0.1919
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0084 0.0511 0.1289
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0164 0.5946
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.0907 0.1847
Echinococcus multilocularis nuclear receptor nhr 48 0.0084 0.0511 0.1035
Leishmania major cathepsin L-like protease 0.0063 0.0234 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Schistosoma mansoni ankyrin 23/unc44 0.0058 0.0179 0.0356
Echinococcus granulosus ecdysone induced protein 78C 0.0179 0.1722 0.3517
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0179 0.1722 0.2492
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0426 0.4884 1
Brugia malayi nuclear receptor RXR 0.0084 0.0511 0.074
Echinococcus granulosus Nuclear hormone receptor HR96 0.0084 0.0511 0.1035
Echinococcus granulosus thyroid hormone receptor alpha 0.0084 0.0511 0.1035
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0424 0.4855 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0058 0.0084
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0179 0.1722 0.3538
Loa Loa (eye worm) hypothetical protein 0.0584 0.691 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Schistosoma mansoni thyroid hormone receptor 0.0179 0.1722 0.3538
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.016 0.1485 0.2149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0179 0.1722 0.2492
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0179 0.1722 0.3517
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0179 0.1722 0.3517
Schistosoma mansoni coup transcription factor 0.0179 0.1722 0.3538
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0006 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0234 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0179 0.1722 0.3517
Echinococcus granulosus jun protein 0.0426 0.4884 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0179 0.1722 0.3517
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0179 0.1722 0.2492
Onchocerca volvulus 0.0179 0.1722 0.4582
Schistosoma mansoni hypothetical protein 0.0058 0.0179 0.0356
Schistosoma mansoni jun-related protein 0.0346 0.3862 0.7953
Brugia malayi Death domain containing protein 0.0058 0.0179 0.0259
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0511 0.1035
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.2407 0.4923
Brugia malayi nuclear hormone receptor family member odr-7 0.0084 0.0511 0.074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0179 0.1722 0.2492
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0095 0.0641 0.1309
Brugia malayi Immunoglobulin I-set domain containing protein 0.0058 0.0179 0.0259
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0095 0.0641 0.0927
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0179 0.1722 0.3538
Echinococcus multilocularis netrin receptor unc 5 0.0058 0.0179 0.0354
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0511 0.1041
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0043 0.0075
Schistosoma mansoni nuclear hormone receptor 0.0179 0.1722 0.3538
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0195 0.1932 0.2796
Brugia malayi hypothetical protein 0.0232 0.2407 0.3484
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Brugia malayi nuclear hormone receptor 0.0179 0.1722 0.2492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Echinococcus granulosus nuclear factor of activated T cells 5 0.0299 0.3264 0.6678
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0058 0.0179 0.0354
Brugia malayi hypothetical protein 0.0334 0.3713 0.5373
Brugia malayi hypothetical protein 0.016 0.1485 0.2149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0179 0.1722 0.2492
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0179 0.1722 0.3517
Brugia malayi nuclear receptor NHR-67 0.0084 0.0511 0.074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0084 0.0511 0.1035
Echinococcus granulosus netrin receptor unc 5 0.0058 0.0179 0.0354
Loa Loa (eye worm) hypothetical protein 0.0058 0.0179 0.0259
Brugia malayi Steroid receptor seven-up type 2 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Schistosoma mansoni nuclear receptor nhr-48 0.0084 0.0511 0.1041
Schistosoma mansoni survival motor neuron protein 0.0047 0.0038 0.0065
Onchocerca volvulus Protein ultraspiracle homolog 0.0179 0.1722 0.4582
Mycobacterium ulcerans proteasome PrcA 0.0825 1 0.5
Brugia malayi Protein kinase domain containing protein 0.0058 0.0179 0.0259
Loa Loa (eye worm) hypothetical protein 0.0232 0.2407 0.3484
Brugia malayi bZIP transcription factor family protein 0.0426 0.4884 0.7068
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0179 0.1722 0.3517
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0276 0.2963 0.6061
Brugia malayi Nuclear hormone receptor-like 1 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0927
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0825 1 0.5
Echinococcus granulosus death domain containing protein 0.0058 0.0179 0.0354
Brugia malayi conserved hypotetical protein 0.0084 0.0511 0.074
Loa Loa (eye worm) DR-78 0.0084 0.0511 0.074
Brugia malayi hypothetical protein 0.0095 0.0641 0.0927
Brugia malayi hypothetical protein 0.0095 0.0641 0.0927
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0179 0.1722 0.3538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0095 0.0641 0.1309
Brugia malayi Nuclear hormone receptor E75 0.0084 0.0511 0.074
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0058 0.0084
Schistosoma mansoni retinoic acid receptor RXR 0.0276 0.2963 0.6097
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0059 0.0185 0.0369
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0095 0.0641 0.1301
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0927
Schistosoma mansoni nuclear receptor 0.0084 0.0511 0.1041
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0179 0.1722 0.2492
Brugia malayi nuclear hormone receptor 0.0084 0.0511 0.074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Schistosoma mansoni RAR-like nuclear receptor 0.0179 0.1722 0.3538
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0058 0.0179 0.0354
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Echinococcus multilocularis FTZ F1 alpha 0.0179 0.1722 0.3517
Brugia malayi ecdysone receptor 0.0084 0.0511 0.074
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0084 0.0511 0.074
Onchocerca volvulus 0.0084 0.0511 0.1289
Echinococcus granulosus Ankyrin 0.0059 0.0185 0.0367
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0927
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Brugia malayi Nuclear hormone receptor-like 1 0.0095 0.0641 0.0927
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0179 0.1722 0.2492
Schistosoma mansoni lipoxygenase 0.0081 0.0463 0.0941
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0927
Brugia malayi hypoxia-induced factor 1 0.0148 0.1326 0.1919
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0234 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0181 0.1752 0.358
Schistosoma mansoni hypothetical protein 0.0047 0.0038 0.0065
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0179 0.1722 0.3517
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Echinococcus granulosus nuclear receptor nhr 48 0.0084 0.0511 0.1035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0179 0.1722 0.3517
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0234 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0084 0.0511 0.074
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0179 0.1722 0.4582
Schistosoma mansoni nuclear receptor 0.0084 0.0511 0.1041
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Brugia malayi small heat shock protein 0.0584 0.691 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0179 0.1722 0.2492
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.0907 0.1847
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0179 0.1722 0.3538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Brugia malayi hypothetical protein 0.0084 0.0511 0.074
Onchocerca volvulus 0.0334 0.3713 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Leishmania major cathepsin L-like protease 0.0063 0.0234 0.5
Schistosoma mansoni thyroid hormone receptor 0.0179 0.1722 0.3538
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Onchocerca volvulus 0.0084 0.0511 0.1289
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0084 0.0511 0.1035
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0084 0.0511 0.1035
Loa Loa (eye worm) nuclear hormone receptor 0.0084 0.0511 0.074
Brugia malayi ecdysteroid receptor 0.0179 0.1722 0.2492
Brugia malayi nuclear hormone receptor family member nhr-6 0.0084 0.0511 0.074
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0179 0.1722 0.2492
Onchocerca volvulus Bile acid receptor homolog 0.0179 0.1722 0.4582
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0179 0.1722 0.2492
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0179 0.1722 0.2492
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0058 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0179 0.1722 0.2492
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0299 0.3264 0.6678
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0426 0.4884 1
Brugia malayi steroid hormone receptor 0.0179 0.1722 0.2492
Schistosoma mansoni hypothetical protein 0.0346 0.3862 0.7953
Brugia malayi hypothetical protein 0.0084 0.0511 0.074
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0179 0.1722 0.3517
Onchocerca volvulus Netrin receptor homolog 0.0058 0.0179 0.0384
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Brugia malayi Nuclear hormone receptor-like 1 0.0095 0.0641 0.0927
Brugia malayi PAS domain containing protein 0.0048 0.0043 0.0062
Brugia malayi Uncoordinated protein 44 0.0058 0.0179 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0084 0.0511 0.074
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0511 0.1041
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0234 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0084 0.0511 0.1041
Loa Loa (eye worm) hypothetical protein 0.0178 0.1716 0.2483
Brugia malayi nuclear receptor NHR-88 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0095 0.0641 0.0927
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0006 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0179 0.1722 0.3517
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0179 0.1722 0.2492
Echinococcus multilocularis jun protein 0.0426 0.4884 1
Leishmania major cathepsin L-like protease 0.0063 0.0234 0.5
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0084 0.0511 0.074
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0179 0.1722 0.3517
Loa Loa (eye worm) hypothetical protein 0.0049 0.0058 0.0084
Echinococcus granulosus FTZ F1 alpha 0.0179 0.1722 0.3517
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0058 0.0179 0.0259
Loa Loa (eye worm) hypothetical protein 0.0336 0.3739 0.5411
Brugia malayi nuclear receptor NHR-88 0.0084 0.0511 0.074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0234 0.5
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0095 0.0641 0.1301
Echinococcus granulosus Nuclear hormone receptor HR96 0.0084 0.0511 0.1035
Echinococcus multilocularis Ankyrin 0.0059 0.0185 0.0367
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0179 0.1722 0.3517
Loa Loa (eye worm) hypothetical protein 0.0179 0.1722 0.2492
Loa Loa (eye worm) hypothetical protein 0.0414 0.4734 0.6852
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.2407 0.4923
Schistosoma mansoni zinc finger protein 0.0084 0.0511 0.1041
Loa Loa (eye worm) hypothetical protein 0.0195 0.1932 0.2796
Loa Loa (eye worm) hypothetical protein 0.0059 0.0185 0.0268

Activities

Activity type Activity value Assay description Source Reference
Change (functional) = 201 % Inactivation processes of human heart Na channel expressed in Xenopus oocytes as increase in current at 10 uM ChEMBL. 7629798
Change (functional) = 378 % Inactivation process of guinea pig cardiac Na channels expressed in xenopus oocytes was determined by measuring increase in current integral in presence of compound versus control at 10 uM ChEMBL. 7629798
Change (functional) = 378 % Inactivation process of guinea pig cardiac Na channels expressed in xenopus oocytes was determined by measuring increase in current integral in presence of compound versus control at 10 uM ChEMBL. 7629798
dP/dt (functional) = 434 nM Concentration of the compound which increased contractility by 20% in rabbit ChEMBL. 7629798
EC20 (functional) = 141 nM Antiarrhythmic activity was determined by measuring the concentration of the compound that produced a 20 ms increase in ERP ChEMBL. 7629798
EC50 (functional) = 160 nM Effective concentration against Xenopus oocytes expressing guinea pig heart Na channel ChEMBL. 7629798
EC50 (functional) = 1600 nM Effective concentration against Xenopus oocytes expressing human heart Na channel ChEMBL. 7629798

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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