Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | thyroid hormone receptor | 0.0254 | 0.2809 | 0.2799 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.012 | 0.1139 | 0.1139 |
Brugia malayi | Inositol-1 | 0.0045 | 0.0202 | 0.0365 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.012 | 0.1139 | 0.2657 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0104 | 0.0091 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0254 | 0.2809 | 0.2799 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.012 | 0.1139 | 0.1127 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0423 | 0.041 |
Brugia malayi | conserved hypotetical protein | 0.012 | 0.1139 | 0.2174 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.012 | 0.1139 | 0.1127 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0254 | 0.2809 | 0.6598 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0254 | 0.2809 | 0.5397 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0104 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1318 | 0.3079 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0118 | 0.111 | 0.111 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.049 | 0.0477 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.049 | 0.1579 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0833 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0056 | 0.0346 | 0.0509 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0254 | 0.2809 | 0.2799 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0254 | 0.2809 | 0.5397 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0072 | 0.0541 | 0.0541 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0044 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0254 | 0.2809 | 0.5397 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0134 | 0.1318 | 0.2519 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.004 | 0.0151 | 0.0138 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0254 | 0.2809 | 0.2799 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0045 | 0.0202 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.2945 | 0.692 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.012 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Onchocerca volvulus | 0.004 | 0.0151 | 0.0477 | |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0314 | 0.3552 | 0.3544 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0254 | 0.2809 | 0.5397 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0156 | 0.0212 |
Schistosoma mansoni | nuclear hormone receptor | 0.012 | 0.1139 | 0.1127 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0086 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1318 | 0.3079 |
Brugia malayi | nuclear receptor RXR | 0.0134 | 0.1318 | 0.2519 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0104 | 0.0214 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0104 | 0.0214 |
Trichomonas vaginalis | set domain proteins, putative | 0.0233 | 0.2547 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0134 | 0.1318 | 0.1306 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0254 | 0.2809 | 0.2799 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0104 | 0.0175 |
Loa Loa (eye worm) | tnks protein | 0.0056 | 0.0346 | 0.0785 |
Onchocerca volvulus | 0.0037 | 0.0104 | 0.0309 | |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0254 | 0.2809 | 0.2799 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.012 | 0.1139 | 0.2174 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0423 | 0.0791 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0013 | 0.0013 |
Brugia malayi | hypothetical protein | 0.012 | 0.1139 | 0.2174 |
Brugia malayi | WGR domain containing protein | 0.0446 | 0.5193 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0104 | 0.0175 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0104 | 0.0214 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.012 | 0.1139 | 0.1139 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.1125 | 0.2625 |
Brugia malayi | hypothetical protein | 0.0134 | 0.1318 | 0.2519 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0045 | 0.0202 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0254 | 0.2809 | 0.5397 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0254 | 0.2809 | 0.2799 |
Onchocerca volvulus | 0.0037 | 0.0104 | 0.0309 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.0334 | 0.062 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.025 | 0.0458 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.012 | 0.1139 | 0.1127 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0254 | 0.2809 | 0.2799 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.012 | 0.1139 | 0.1139 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0254 | 0.2809 | 0.2799 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0049 | 0.0261 | 0.0379 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0254 | 0.2809 | 0.5397 |
Brugia malayi | ecdysteroid receptor | 0.0254 | 0.2809 | 0.5397 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0254 | 0.2809 | 0.6598 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0423 | 0.0967 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0104 | 0.0214 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.006 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0261 | 0.0585 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0254 | 0.2809 | 0.6598 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0254 | 0.2809 | 0.5397 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.012 | 0.1139 | 0.1127 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0202 | 0.0236 |
Entamoeba histolytica | hypothetical protein | 0.0056 | 0.0346 | 0.0509 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.037 | 0.425 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0056 | 0.0346 | 0.0509 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0104 | 0.3664 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0446 | 0.5193 | 0.5186 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.012 | 0.1139 | 0.1139 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0254 | 0.2809 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0254 | 0.2809 | 0.2809 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0334 | 0.0334 |
Onchocerca volvulus | 0.012 | 0.1139 | 0.4017 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0254 | 0.2809 | 0.6598 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.037 | 0.425 | 0.425 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0104 | 0.0104 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.037 | 0.425 | 0.4243 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.037 | 0.425 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0104 | 0.0214 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.037 | 0.425 | 0.4243 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0453 | 0.5274 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0254 | 0.2809 | 0.5397 |
Schistosoma mansoni | thyroid hormone receptor | 0.0254 | 0.2809 | 0.2799 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0254 | 0.2809 | 0.5397 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0049 | 0.0261 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0049 | 0.0261 | 0.5 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0202 | 0.6247 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.012 | 0.0365 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0254 | 0.2809 | 0.2809 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0254 | 0.2809 | 0.2799 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.0334 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0254 | 0.2809 | 0.2799 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.012 | 0.1139 | 0.2657 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Echinococcus granulosus | FTZ F1 alpha | 0.0254 | 0.2809 | 0.2809 |
Brugia malayi | steroid hormone receptor | 0.0254 | 0.2809 | 0.5397 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Brugia malayi | hypothetical protein | 0.0134 | 0.1318 | 0.2519 |
Schistosoma mansoni | inositol monophosphatase | 0.0045 | 0.0202 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1318 | 0.3079 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0254 | 0.2809 | 0.5397 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0049 | 0.0261 | 0.0471 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.049 | 0.092 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.012 | 0.1139 | 0.4017 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0254 | 0.2809 | 0.2809 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0202 | 0.0236 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0446 | 0.5193 | 0.5186 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.425 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0423 | 0.041 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0423 | 0.0791 |
Loa Loa (eye worm) | inositol-1 | 0.0045 | 0.0202 | 0.0446 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0235 | 0.2562 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0254 | 0.2809 | 0.5397 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1318 | 0.3079 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0254 | 0.2809 | 0.5397 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0.0202 | 0.0401 |
Brugia malayi | WGR domain containing protein | 0.037 | 0.425 | 0.818 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.049 | 0.1125 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.012 | 0.1139 | 0.2174 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0.0202 | 0.0401 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Onchocerca volvulus | 0.0254 | 0.2809 | 1 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0049 | 0.0261 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0254 | 0.2809 | 0.2809 |
Echinococcus granulosus | WGR domain containing protein | 0.019 | 0.2003 | 0.2003 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0423 | 0.041 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0423 | 0.0967 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.037 | 0.425 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0104 | 0.0214 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.0252 | 0.046 |
Onchocerca volvulus | Tankyrase homolog | 0.0056 | 0.0346 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Brugia malayi | ecdysone receptor | 0.012 | 0.1139 | 0.2174 |
Brugia malayi | tailless protein | 0.012 | 0.1139 | 0.2174 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0423 | 0.0967 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0254 | 0.2809 | 0.5397 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0254 | 0.2809 | 0.6598 |
Brugia malayi | hypothetical protein | 0.012 | 0.1139 | 0.2174 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0254 | 0.2809 | 0.2799 |
Schistosoma mansoni | inositol monophosphatase | 0.0045 | 0.0202 | 0.0189 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0334 | 0.0321 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0254 | 0.2809 | 0.2799 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0049 | 0.0261 | 0.0379 |
Schistosoma mansoni | zinc finger protein | 0.012 | 0.1139 | 0.1127 |
Schistosoma mansoni | tankyrase | 0.0056 | 0.0346 | 0.0333 |
Schistosoma mansoni | nuclear receptor | 0.012 | 0.1139 | 0.1127 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.006 | 0.009 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0254 | 0.2809 | 0.2809 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.049 | 0.0477 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.012 | 0.0206 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0261 | 0.0478 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.049 | 0.0477 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.019 | 0.2003 | 0.2003 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0134 | 0.1318 | 0.1318 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0334 | 0.0321 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0045 | 0.0202 | 0.0401 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0104 | 0.0175 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0254 | 0.2809 | 0.2809 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.012 | 0.1139 | 0.4017 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0104 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.1318 | 0.3079 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0254 | 0.2809 | 0.2799 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0254 | 0.2809 | 0.6598 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0254 | 0.2809 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.049 | 0.049 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0423 | 0.041 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0254 | 0.2809 | 0.5397 |
Onchocerca volvulus | 0.012 | 0.1139 | 0.4017 | |
Schistosoma mansoni | microtubule-associated protein tau | 0.0833 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.012 | 0.1139 | 0.2657 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.025 | 0.0458 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0254 | 0.2809 | 0.2799 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0254 | 0.2809 | 0.5397 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.012 | 0.1139 | 0.1127 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0134 | 0.1318 | 0.3079 |
Echinococcus multilocularis | tankyrase | 0.0056 | 0.0346 | 0.0333 |
Schistosoma mansoni | nuclear receptor | 0.012 | 0.1139 | 0.1127 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0541 | 0.0891 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.025 | 0.056 |
Schistosoma mansoni | nuclear hormone receptor | 0.012 | 0.1139 | 0.1127 |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.2195 | 0.4212 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0334 | 0.0321 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0104 | 0.0091 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0423 | 0.0791 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.1125 | 0.2625 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0423 | 0.041 |
Echinococcus granulosus | tankyrase | 0.0056 | 0.0346 | 0.0346 |
Brugia malayi | nuclear receptor RXR | 0.012 | 0.1139 | 0.2174 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.012 | 0.1139 | 0.1127 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0254 | 0.2809 | 0.2799 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0086 | 0.0073 |
Echinococcus multilocularis | poly (ADP ribose) polymerase | 0.0128 | 0.1239 | 0.1228 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0253 | 0.2789 | 0.655 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0086 | 0.0073 |
Entamoeba histolytica | zinc finger protein, putative | 0.0056 | 0.0346 | 0.0509 |
Brugia malayi | Tnks protein | 0.0056 | 0.0346 | 0.0642 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0045 | 0.0202 | 0.0189 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0134 | 0.1318 | 0.2519 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0018 | 0.0011 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0086 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0254 | 0.2809 | 0.5397 |
Schistosoma mansoni | coup transcription factor | 0.0254 | 0.2809 | 0.2799 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.049 | 0.1579 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0254 | 0.2809 | 0.2809 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0254 | 0.2809 | 0.5397 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.049 | 0.0477 |
Leishmania major | hypothetical protein, conserved | 0.0049 | 0.0261 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.012 | 0.1139 | 0.1127 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.1125 | 0.2147 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0254 | 0.2809 | 0.2799 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Brugia malayi | Nuclear hormone receptor E75 | 0.012 | 0.1139 | 0.2174 |
Onchocerca volvulus | 0.0233 | 0.2547 | 0.906 | |
Brugia malayi | nuclear hormone receptor | 0.012 | 0.1139 | 0.2174 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0334 | 0.0334 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0045 | 0.0202 | 0.0227 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.0252 | 0.0562 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0423 | 0.0423 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.012 | 0.1139 | 0.2174 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0254 | 0.2809 | 0.2799 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.012 | 0.0065 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0104 | 0.0175 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0254 | 0.2809 | 0.2799 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0104 | 0.0214 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0045 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0254 | 0.2809 | 0.6598 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0254 | 0.2809 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.012 | 0.1139 | 0.2174 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0334 | 0.0321 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.012 | 0.1139 | 0.2174 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.025 | 0.056 |
Brugia malayi | nuclear receptor NHR-67 | 0.012 | 0.1139 | 0.2174 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Schistosoma mansoni | nuclear hormone receptor | 0.0254 | 0.2809 | 0.2799 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0254 | 0.2809 | 0.2809 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.004 | 0.0144 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.012 | 0.1139 | 0.1127 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0156 | 0.0494 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1139 | 0.2657 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0254 | 0.2809 | 0.6598 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0134 | 0.1318 | 0.1306 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0202 | 0.0236 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.012 | 0.1139 | 0.1139 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.012 | 0.1139 | 0.1127 |
Onchocerca volvulus | 0.0037 | 0.0104 | 0.0309 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Loa Loa (eye worm) | DR-78 | 0.012 | 0.1139 | 0.2657 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Entamoeba histolytica | hypothetical protein | 0.0056 | 0.0346 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.006 | 0.011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.049 | 0.049 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.2195 | 0.5148 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0156 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.012 | 0.0252 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.012 | 0.1139 | 0.1139 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0134 | 0.1318 | 0.1306 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0423 | 0.041 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0446 | 0.5193 | 1 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0446 | 0.5193 | 0.5193 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0334 | 0.0321 |
Brugia malayi | Nuclear hormone receptor E75 | 0.012 | 0.1139 | 0.2174 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0072 | 0.0541 | 0.0541 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.004 | 0.0144 | 0.0163 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0104 | 0.0091 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0254 | 0.2809 | 0.5397 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0049 | 0.0261 | 0.0379 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0056 | 0.0346 | 0.099 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0045 | 0.0202 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2809 | 0.6598 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antagonist activity at rat cannabinoid CB1 receptor in Wistar rat cerebellar membranes at 10 uM by [35S]GTPgammaS binding assay | ChEMBL. | 21215643 | |
Activity (functional) | = 7 % | Agonist activity at human recombinant cannabinoid CB2 receptor expressed in CHO cells at 10 uM by [35S]GTPgammaS binding assay | ChEMBL. | 21215643 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.