TDR Targets

Basic information

Technical information

TDR Targets ID: 1469112
Name: 2-[(5-furan-2-yl-4-methyl-1,2,4-triazol-3-yl) sulfanyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)b utanamide
MW: 364.446 | Formula: C14H16N6O2S2
H donors: 1 H acceptors: 5 LogP: 2.04 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CCC(C(=O)Nc1nnc(s1)C)Sc1nnc(n1C)c1ccco1
InChi: 1S/C14H16N6O2S2/c1-4-10(12(21)15-13-18-16-8(2)23-13)24-14-19-17-11(20(14)3)9-6-5-7-22-9/h5-7,10H,4H2,1-3H3,(H,15,18,21)
InChiKey: RPKGATSDADDSDV-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-[[5-(2-furyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)butanamide
2-[[5-(2-furyl)-4-methyl-1,2,4-triazol-3-yl]thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)butanamide
2-[[5-(2-furyl)-4-methyl-1,2,4-triazol-3-yl]thio]-N-(5-methyl-1,3,4-thiadiazol-2-yl)butyramide
ASN 15350567
STK230766

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	glycoprotein hormones, alpha polypeptide	Starlite/ChEMBL	No references
Homo sapiens	relaxin/insulin-like family peptide receptor 1	Starlite/ChEMBL	No references
Homo sapiens	APEX nuclease (multifunctional DNA repair enzyme) 1	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Toxoplasma gondii	exonuclease III APE	Get druggable targets OG5_126768	All targets in OG5_126768
Leishmania braziliensis	apurinic/apyrimidinic endonuclease-redox protein	Get druggable targets OG5_126768	All targets in OG5_126768
Neospora caninum	hypothetical protein	Get druggable targets OG5_126768	All targets in OG5_126768
Leishmania mexicana	apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease	Get druggable targets OG5_126768	All targets in OG5_126768
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Theileria parva	hypothetical protein	Get druggable targets OG5_126768	All targets in OG5_126768
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	Get druggable targets OG5_126768	All targets in OG5_126768
Brugia malayi	exodeoxyribonuclease III family protein	Get druggable targets OG5_126768	All targets in OG5_126768
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	Get druggable targets OG5_126768	All targets in OG5_126768
Trichomonas vaginalis	ap endonuclease, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Trypanosoma brucei gambiense	apurinic/apyrimidinic endonuclease, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Schistosoma japonicum	ko:K10771 AP endonuclease 1, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	Get druggable targets OG5_126768	All targets in OG5_126768
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	Get druggable targets OG5_126768	All targets in OG5_126768
Schistosoma mansoni	ap endonuclease	Get druggable targets OG5_126768	All targets in OG5_126768
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	Get druggable targets OG5_126768	All targets in OG5_126768
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	Get druggable targets OG5_126768	All targets in OG5_126768
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	Get druggable targets OG5_126768	All targets in OG5_126768
Cryptosporidium parvum	conserved hypothetical protein	Get druggable targets OG5_126768	All targets in OG5_126768
Treponema pallidum	exodeoxyribonuclease (exoA)	Get druggable targets OG5_126768	All targets in OG5_126768
Schistosoma mansoni	ap endonuclease	Get druggable targets OG5_126768	All targets in OG5_126768
Schistosoma japonicum	DNA-(apurinic or apyrimidinic site) lyase 2, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Candida albicans	similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease	Get druggable targets OG5_126768	All targets in OG5_126768
Plasmodium yoelii	putative AP endonuclease-related	Get druggable targets OG5_126768	All targets in OG5_126768
Leishmania infantum	apurinic/apyrimidinic endonuclease-redox protein	Get druggable targets OG5_126768	All targets in OG5_126768
Candida albicans	similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease	Get druggable targets OG5_126768	All targets in OG5_126768
Plasmodium berghei	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	Get druggable targets OG5_126768	All targets in OG5_126768
Leishmania donovani	apurinic/apyrimidinic endonuclease-redox protein	Get druggable targets OG5_126768	All targets in OG5_126768
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	Get druggable targets OG5_126768	All targets in OG5_126768
Cryptosporidium hominis	dna-(apurinic or apyrimidinic site) lyase	Get druggable targets OG5_126768	All targets in OG5_126768
Trypanosoma congolense	apurinic/apyrimidinic endonuclease, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Schistosoma japonicum	DNA-(apurinic or apyrimidinic site) lyase 2, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi	exonuclease III	Get druggable targets OG5_126768	All targets in OG5_126768
Entamoeba histolytica	exodeoxyribonuclease III, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Plasmodium knowlesi	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	Get druggable targets OG5_126768	All targets in OG5_126768
Trichomonas vaginalis	ap endonuclease, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	Get druggable targets OG5_126768	All targets in OG5_126768
Schistosoma japonicum	ko:K10772 AP endonuclease 2, putative	Get druggable targets OG5_126768	All targets in OG5_126768
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	Get druggable targets OG5_126768	All targets in OG5_126768

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Toxoplasma gondii	intraflagellar transport protein 172, putative	glycoprotein hormones, alpha polypeptide	116 aa	94 aa	26.6 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	neurogenic locus notch protein	0.0017	0.2396	0.2396
Schistosoma mansoni	hypothetical protein	0.0017	0.2396	0.2396
Brugia malayi	EGF-like domain containing protein	0.0017	0.2427	0.2427
Echinococcus multilocularis	neurogenic locus protein delta	0.0017	0.2396	0.2396
Brugia malayi	Animal haem peroxidase family protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	protein jagged 1	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	animal heme peroxidase	0.0053	0.9969	0.9969
Echinococcus multilocularis	fat cadherin tumor suppressor	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Onchocerca volvulus		0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Brugia malayi	Animal haem peroxidase family protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2427	0.2427
Brugia malayi	Animal haem peroxidase family protein	0.0053	0.9969	0.9969
Schistosoma mansoni	cell polarity protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	neurogenic locus notch protein 4	0.0017	0.2396	0.2396
Schistosoma mansoni	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	neurogenic locus notch protein	0.0017	0.2396	0.2396
Brugia malayi	Delta serrate ligand family protein	0.0017	0.2396	0.2396
Echinococcus granulosus	neurogenic locus notch protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	neurogenic locus notch protein	0.0017	0.2396	0.2396
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0023	0.3584	0.5
Schistosoma mansoni	notch	0.0017	0.2396	0.2396
Schistosoma mansoni	notch	0.0017	0.2396	0.2396
Brugia malayi	EGF-like domain containing protein	0.0017	0.2396	0.2396
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0023	0.3584	0.5
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	slit 2 protein	0.0017	0.2427	0.2427
Echinococcus multilocularis	protein jagged 2	0.0017	0.2396	0.2396
Brugia malayi	Cadherin domain containing protein	0.0017	0.2396	0.2396
Echinococcus granulosus	protein jagged 2	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0023	0.3584	0.5
Brugia malayi	EGF-like domain containing protein	0.0017	0.2396	0.2396
Schistosoma mansoni	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	fibropellin Ia	0.0017	0.2396	0.2396
Onchocerca volvulus		0.0017	0.2396	0.2396
Schistosoma mansoni	peroxidasin	0.0053	0.9969	0.9969
Echinococcus multilocularis	neural cadherin	0.0017	0.2396	0.2396
Echinococcus granulosus	neural cadherin	0.0017	0.2396	0.2396
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0023	0.3584	0.3584
Onchocerca volvulus		0.0017	0.2396	0.2396
Onchocerca volvulus	Peroxidasin homolog	0.0053	1	1
Brugia malayi	Animal haem peroxidase family protein	0.0053	0.9969	0.9969
Brugia malayi	EGF-like domain containing protein	0.0017	0.2396	0.2396
Echinococcus granulosus	notch	0.0017	0.2396	0.2396
Echinococcus granulosus	neurogenic locus notch protein 4	0.0017	0.2396	0.2396
Schistosoma mansoni	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus granulosus	protein jagged 1	0.0017	0.2396	0.2396
Echinococcus granulosus	slit 2 protein	0.0017	0.2427	0.2427
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Trichomonas vaginalis	ap endonuclease, putative	0.0023	0.3584	0.5
Onchocerca volvulus		0.0053	0.9969	0.9969
Schistosoma mansoni	notch	0.0017	0.2396	0.2396
Schistosoma mansoni	notch	0.0017	0.2396	0.2396
Onchocerca volvulus	Peroxidasin homolog	0.0053	0.9969	0.9969
Schistosoma mansoni	notch	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Onchocerca volvulus		0.0053	0.9969	0.9969
Schistosoma mansoni	hypothetical protein	0.0017	0.2396	0.2396
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0023	0.3584	0.5
Brugia malayi	Calcium binding EGF domain containing protein	0.0017	0.2396	0.2396
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0023	0.3584	0.5
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0023	0.3584	0.3584
Brugia malayi	EGF-like domain containing protein	0.0017	0.2396	0.2396
Brugia malayi	Blistered cuticle protein 3	0.0053	0.9969	0.9969
Schistosoma mansoni	septate junction protein	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Onchocerca volvulus	Dual oxidase homolog	0.0053	0.9969	0.9969
Schistosoma mansoni	Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)]	0.0017	0.2396	0.2396
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0023	0.3584	0.5
Echinococcus multilocularis	peroxidasin	0.0053	1	1
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0023	0.3584	0.5
Onchocerca volvulus		0.0017	0.2396	0.2396
Loa Loa (eye worm)	Notch2	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	neurogenic locus protein delta	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Onchocerca volvulus	Peroxidase homolog	0.0053	0.9969	0.9969
Loa Loa (eye worm)	animal heme peroxidase	0.0053	0.9969	0.9969
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0023	0.3584	0.5
Echinococcus granulosus	protein jagged 1	0.0017	0.2396	0.2396
Echinococcus granulosus	protein jagged 2	0.0017	0.2396	0.2396
Echinococcus granulosus	fibropellin Ia	0.0017	0.2396	0.2396
Trichomonas vaginalis	ap endonuclease, putative	0.0023	0.3584	0.5
Brugia malayi	GCC2 and GCC3 family protein	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Brugia malayi	Transmembrane cell adhesion receptor mua-3 precursor, putative	0.0017	0.2396	0.2396
Brugia malayi	exodeoxyribonuclease III family protein	0.0023	0.3584	0.3584
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0023	0.3584	1
Echinococcus granulosus	peroxidasin	0.0053	1	1
Onchocerca volvulus	Peroxidase homolog	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Onchocerca volvulus	Slit protein homolog	0.0017	0.2427	0.2427
Brugia malayi	hypothetical protein	0.0053	0.9969	0.9969
Echinococcus granulosus	delta-like protein 1	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	blistered cuticle protein 3	0.0053	0.9969	0.9969
Loa Loa (eye worm)	animal heme peroxidase	0.0053	0.9969	0.9969
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0023	0.3584	0.5
Brugia malayi	Muscle positioning protein 4	0.0017	0.2396	0.2396
Brugia malayi	notch-like transmembrane receptor	0.0017	0.2396	0.2396
Schistosoma mansoni	hypothetical protein	0.0017	0.2396	0.2396
Schistosoma mansoni	peroxidasin	0.0053	1	1
Loa Loa (eye worm)	notch protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	notch	0.0017	0.2396	0.2396
Schistosoma mansoni	hypothetical protein	0.0017	0.2396	0.2396
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0023	0.3584	0.5
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Schistosoma mansoni	laminin gamma-3 chain	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Brugia malayi	Animal haem peroxidase family protein	0.0053	0.9969	0.9969
Toxoplasma gondii	exonuclease III APE	0.0023	0.3584	1
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Onchocerca volvulus		0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Brugia malayi	Cadherin domain containing protein	0.0017	0.2396	0.2396
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0023	0.3584	0.3584
Onchocerca volvulus	Neurogenic locus notch homolog	0.0017	0.2396	0.2396
Schistosoma mansoni	slit	0.0017	0.2427	0.2427
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Brugia malayi	EGF-like domain containing protein	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Onchocerca volvulus	Chorion peroxidase homolog	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Brugia malayi	Calcium binding EGF domain containing protein	0.0017	0.2396	0.2396
Brugia malayi	EGF-like domain containing protein	0.0017	0.2396	0.2396
Brugia malayi	Calcium binding EGF domain containing protein	0.0017	0.2396	0.2396
Schistosoma mansoni	ap endonuclease	0.0023	0.3584	0.3584
Schistosoma mansoni	ap endonuclease	0.0023	0.3584	0.3584
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0023	0.3584	0.5
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Echinococcus multilocularis	protein jagged 1	0.0017	0.2396	0.2396
Schistosoma mansoni	notch	0.0017	0.2396	0.2396
Onchocerca volvulus	Neurogenic locus notch protein homolog	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Loa Loa (eye worm)	animal heme peroxidase	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Echinococcus granulosus	neurogenic locus protein delta	0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	1	1
Onchocerca volvulus		0.0017	0.2396	0.2396
Loa Loa (eye worm)	hypothetical protein	0.0053	0.9969	0.9969
Loa Loa (eye worm)	hypothetical protein	0.0017	0.2396	0.2396
Onchocerca volvulus	Putative cubilin	0.0017	0.2396	0.2396

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	0.5323 uM	PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	3.9811 uM	PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	= 17.7828 um	PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	31.6228 uM	PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1501425

Bibliographic References

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Detailed information for compound 1469112