Detailed information for compound 1469902

Basic information

Technical information
  • TDR Targets ID: 1469902
  • Name: N-(2,5-diethoxyphenyl)-2-(4-propylpiperazin-1 -yl)acetamide
  • MW: 349.468 | Formula: C19H31N3O3
  • H donors: 1 H acceptors: 1 LogP: 2.55 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN1CCN(CC1)CC(=O)Nc1cc(OCC)ccc1OCC
  • InChi: 1S/C19H31N3O3/c1-4-9-21-10-12-22(13-11-21)15-19(23)20-17-14-16(24-5-2)7-8-18(17)25-6-3/h7-8,14H,4-6,9-13,15H2,1-3H3,(H,20,23)
  • InChiKey: UCJFGCBOEMJPFI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,5-diethoxyphenyl)-2-(4-propyl-1-piperazinyl)acetamide
  • N-(2,5-diethoxyphenyl)-2-(4-propylpiperazin-1-yl)ethanamide
  • ASN 09858504
  • N-(2,5-Diethoxy-phenyl)-2-(4-propyl-piperazin-1-yl)-acetamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1797 1 1
Schistosoma mansoni hypothetical protein 0.0118 0.0402 0.0195
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.004 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0546 0.285 0.6497
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.017 0.0703 0.2004
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0118 0.0402 0.1115
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0277 0.1313 0.2969
Echinococcus granulosus serine protein kinase ATM 0.0315 0.1528 0.152
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.0057
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0706 0.3762 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0277 0.1313 0.2969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0459 0.2355 0.536
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0277 0.1313 0.2969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0607 0.3201 0.7304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0656 0.3481 0.7946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.3129 0.7139
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0625 0.3303 0.7537
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0118 0.0402 0.5565
Brugia malayi Heterochromatin protein 1 0.0084 0.0211 0.0172
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0441 0.225 0.2218
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0625 0.3303 0.3022
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0402 0.0738
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0461 0.2367 0.5388
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0706 0.3762 0.8455
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0146 0.0256
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.017 0.0703 0.1567
Trichomonas vaginalis PIKK family atypical protein kinase 0.0582 0.3054 0.6965
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1797 1 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0625 0.3303 0.878
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.1747 0.4645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0166 0.0682 0.1518
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0066 0.0105
Entamoeba histolytica hypothetical protein 0.0315 0.1528 0.4063
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0625 0.3303 0.3022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0197 0.0857 0.192
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0402 0.0392
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0118 0.0402 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0075 0.0123
Loa Loa (eye worm) phosphatidylinositol 3 0.0706 0.3762 0.7058
Echinococcus multilocularis serine protein kinase ATM 0.0315 0.1528 0.152
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0277 0.1313 0.3492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.2089 0.4749
Loa Loa (eye worm) phosphatidylinositol 3 0.016 0.0642 0.1189
Onchocerca volvulus 0.0118 0.0402 1
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0441 0.225 0.2242
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0706 0.3762 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.0402 0.0738
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0706 0.3762 0.35
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0315 0.1528 0.1494
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0389 0.0379
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0025 0.001
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0216 0.0962 0.141
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0334 0.1639 0.4357
Toxoplasma gondii target of rapamycin (TOR), putative 0.0644 0.341 1
Entamoeba histolytica hypothetical protein 0.0118 0.0402 0.1069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.2089 0.4749
Echinococcus granulosus chromobox protein 1 0.0084 0.0211 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0349 0.1724 0.3911
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0315 0.1528 0.1494
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0118 0.0402 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0644 0.341 0.7784
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.017 0.0703 0.1869
Trichomonas vaginalis PIKK family atypical protein kinase 0.0644 0.341 0.7784
Entamoeba histolytica hypothetical protein 0.0118 0.0402 0.1069
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0211 0.0438
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0118 0.0402 0.0876
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0277 0.1313 0.1279
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0706 0.3762 0.35
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0315 0.1528 0.1173
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.017 0.0703 0.0502
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Trichomonas vaginalis PIKK family atypical protein kinase 0.0656 0.3481 0.7946
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.1747 0.5
Loa Loa (eye worm) hypothetical protein 0.0197 0.0857 0.1593
Loa Loa (eye worm) hypothetical protein 0.0184 0.0784 0.1455
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0702 0.0693
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0211 0.0379
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0118 0.0402 0.5719
Trichomonas vaginalis PIKK family atypical protein kinase 0.0706 0.3762 0.8591
Brugia malayi FAT domain containing protein 0.0231 0.1052 0.1016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.3129 0.7139
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1086 0.5936 0.5931
Schistosoma mansoni hypothetical protein 0.0231 0.1052 0.0859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0315 0.1528 0.3463
Leishmania major phosphatidylinositol 3-kinase, putative 0.017 0.0703 0.0757
Schistosoma mansoni fkbp-rapamycin associated protein 0.0315 0.1528 0.1346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0706 0.3762 0.8591
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.017 0.0703 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0197 0.0857 0.192
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0625 0.3303 0.7537
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0277 0.1313 0.3492
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1797 1 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.017 0.0703 0.2004
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0224 0.1013 0.2692
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Trichomonas vaginalis PIKK family atypical protein kinase 0.0644 0.341 0.7784
Giardia lamblia GTOR 0.0706 0.3762 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0461 0.2367 0.5388
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.017 0.0703 0.0693
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0518 0.2692 0.7157
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.017 0.0703 0.1567
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0118 0.0402 0.0364
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0277 0.1313 0.095
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0175 0.073 0.0531
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.1747 0.4645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0644 0.341 0.7784
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0706 0.3762 0.3737
Onchocerca volvulus 0.0118 0.0402 1
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0441 0.225 0.2242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.3131 0.7142
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0118 0.0402 0.0195
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0118 0.0402 0.5719
Trichomonas vaginalis PIKK family atypical protein kinase 0.0656 0.3481 0.7946
Loa Loa (eye worm) acetyltransferase 0.0175 0.073 0.1356
Trichomonas vaginalis PIKK family atypical protein kinase 0.0546 0.285 0.6497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0315 0.1528 0.3463
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.3131 0.7142
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0118 0.0402 0.5565
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Loa Loa (eye worm) hypothetical protein 0.0349 0.1724 0.3224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0656 0.3481 0.7946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0546 0.285 0.6497
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0025 0.0014
Plasmodium vivax hypothetical protein 0.0118 0.0402 0.5565
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.0716 1
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.017 0.0703 0.1304
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0508 0.2631 0.6995
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1086 0.5936 0.5848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0607 0.3201 0.7304
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0277 0.1313 0.2294
Loa Loa (eye worm) hypothetical protein 0.0267 0.1256 0.2344
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1797 1 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0175 0.073 0.0721
Trichomonas vaginalis PIKK family atypical protein kinase 0.0546 0.285 0.6497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.3131 0.7142
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0315 0.1528 0.152
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.017 0.0703 0.0666
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0625 0.3303 0.7537
Echinococcus granulosus chromobox protein 1 0.0084 0.0211 0.0201
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.0716 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1797 1 1
Loa Loa (eye worm) hypothetical protein 0.0267 0.1256 0.2344
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.017 0.0703 0.0693
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0231 0.1052 0.1043
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.017 0.0703 0.1869
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0813 0.4375 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0025 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.3131 0.7142
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.1747 0.4645
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.017 0.0703 0.0314
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0211 0.0438
Echinococcus multilocularis chromobox protein 1 0.0084 0.0211 0.0201
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0118 0.0402 0.0364
Entamoeba histolytica protein kinase rad3, putative 0.0315 0.1528 0.4063
Giardia lamblia Phosphatidylinositol 4-kinase 0.0118 0.0402 0.1069
Loa Loa (eye worm) hypothetical protein 0.0315 0.1528 0.2857
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0118 0.0402 0.5565
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0118 0.0402 0.1115
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0315 0.1528 0.2835
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0461 0.2363 0.2333
Trichomonas vaginalis conserved hypothetical protein 0.0231 0.1052 0.2369
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0349 0.1724 0.5019
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0706 0.3762 0.3627
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0398 0.2004 0.4032
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0118 0.0402 0.1115
Brugia malayi acetyltransferase, GNAT family protein 0.0175 0.073 0.0693
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.3129 0.7139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0425 0.2159 0.4912
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0118 0.0402 0.0876
Echinococcus multilocularis 0.0118 0.0402 0.0392
Loa Loa (eye worm) hypothetical protein 0.0441 0.225 0.4214
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0582 0.3054 0.8118
Loa Loa (eye worm) phosphatidylinositol kinase 0.0118 0.0402 0.0738
Trichomonas vaginalis PIKK family atypical protein kinase 0.0644 0.341 0.7784
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0118 0.0402 0.0364
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0706 0.3762 0.8455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0402 0.0876
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0402 0.0392
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Schistosoma mansoni phosphatidylinositol 4-kinase 0.017 0.0703 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0644 0.341 0.7784
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.016 0.0642 0.025
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1086 0.5936 0.5931
Entamoeba histolytica hypothetical protein 0.0518 0.2692 0.7157
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0118 0.0402 0.0392
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0315 0.1528 0.1173
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.017 0.0703 0.0757
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0118 0.0402 0.0392
Loa Loa (eye worm) phosphatidylinositol 3 0.0979 0.5325 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0546 0.285 0.6161
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0118 0.0402 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0813 0.4375 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0881 0.4766 0.4761
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0315 0.1528 0.1346
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0277 0.1313 0.1126
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0254 0.0044
Echinococcus multilocularis Zinc finger, PHD finger 0.017 0.0703 0.0693
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.017 0.0703 0.0693
Giardia lamblia Hypothetical protein 0.0118 0.0402 0.1069
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0402 0.0392
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0706 0.3762 0.3755
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0402 0.5565
Trichomonas vaginalis PIKK family atypical protein kinase 0.0413 0.2089 0.4749
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0657 0.3482 0.7752
Trypanosoma cruzi target of rapamycin kinase 3 0.0657 0.3482 0.3209
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0402 0.0738
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0402 0.0738
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0706 0.3762 0.3755
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Brugia malayi jmjC domain containing protein 0.0115 0.0389 0.0351
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0706 0.3762 0.8455
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0402 0.0392
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0118 0.0402 0.1069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0644 0.341 0.7784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0656 0.3481 0.7946
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0657 0.3482 0.7752
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.017 0.0703 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0625 0.3303 0.3276
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0231 0.1052 0.1043
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.017 0.0703 0.1567
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0355 0.1756 0.4669
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0706 0.3762 0.8455
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.017 0.0703 0.0757
Loa Loa (eye worm) phosphatidylinositol 3 0.0813 0.4375 0.8213
Loa Loa (eye worm) hypothetical protein 0.0231 0.1052 0.196
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0402 0.0738
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.0716 0.5
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0197 0.0857 0.0474
Brugia malayi Cytochrome P450 family protein 0.0059 0.0066 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0402 0.0876
Toxoplasma gondii FATC domain-containing protein 0.0315 0.1528 0.4442
Trichomonas vaginalis PIKK family atypical protein kinase 0.0474 0.244 0.5556
Entamoeba histolytica hypothetical protein 0.0118 0.0402 0.1069
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0315 0.1528 0.152
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.1747 0.3965
Plasmodium falciparum phosphatidylinositol 3-kinase 0.017 0.0703 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0546 0.285 0.6161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0706 0.3762 0.8591
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0813 0.4375 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0389 0.0379
Echinococcus multilocularis chromobox protein 1 0.0084 0.0211 0.0201

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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