TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 445.598 | Formula: C24H39N5O3
H donors: 5 H acceptors: 3 LogP: 1.69 Rotable bonds: 14
Rule of 5 violations (Lipinski): 1
SMILES: NCCC[C@@H](C(=O)NC1CCCc2c1cccc2)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC)C
InChi: 1S/C24H39N5O3/c1-15(2)21(29-22(30)16(3)26-4)24(32)28-20(13-8-14-25)23(31)27-19-12-7-10-17-9-5-6-11-18(17)19/h5-6,9,11,15-16,19-21,26H,7-8,10,12-14,25H2,1-4H3,(H,27,31)(H,28,32)(H,29,30)/t16-,19?,20-,21-/m0/s1
InChiKey: WDMKUTLEJONAPH-WXYFQQAYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	inhibitor of apoptosis protein	0.0065	0.0242	0.0216
Echinococcus multilocularis	baculoviral IAP repeat containing protein	0.0065	0.0242	0.0208
Entamoeba histolytica	cell division protein kinase 2, putative	0.0066	0.0245	0.0207
Schistosoma mansoni	voltage-gated potassium channel	0.0038	0.0074	0.0047
Schistosoma mansoni	voltage-gated potassium channel	0.0209	0.1124	0.11
Echinococcus granulosus	inhibitor of apoptosis protein	0.0065	0.0242	0.0208
Trichomonas vaginalis	CMGC family protein kinase	0.1658	1	1
Onchocerca volvulus	Casein kinase II subunit beta homolog	0.015	0.0762	0.7287
Trichomonas vaginalis	protein kinase ck2-beta, putative	0.0044	0.011	0.0072
Schistosoma mansoni	serine/threonine protein kinase	0.0194	0.1031	0.1007
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trypanosoma cruzi	cdc2-related kinase 3	0.0066	0.0245	0.0245
Loa Loa (eye worm)	CMGC/DYRK/DYRK1 protein kinase	0.0193	0.1026	0.0991
Trichomonas vaginalis	CMGC family protein kinase	0.0232	0.1265	0.1231
Plasmodium falciparum	casein kinase II beta chain	0.015	0.0762	0.0726
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0038	0.0074	0.0047
Schistosoma mansoni	serine/threonine protein kinase	0.0044	0.0112	0.0086
Schistosoma mansoni	serine/threonine protein kinase	0.0044	0.0112	0.0086
Echinococcus granulosus	dual specificity	0.0232	0.1265	0.1235
Plasmodium falciparum	DNA gyrase subunit A	0.0111	0.0519	0.0482
Entamoeba histolytica	protein kinase domain containing protein	0.0703	0.4145	0.4122
Schistosoma mansoni	voltage-gated potassium channel	0.0056	0.0182	0.0156
Onchocerca volvulus	Casein kinase II subunit beta homolog	0.015	0.0762	0.7287
Echinococcus multilocularis	cyclin dependent kinase 5	0.0066	0.0245	0.0212
Trichomonas vaginalis	CMGC family protein kinase	0.0071	0.0279	0.0241
Echinococcus granulosus	voltage gated potassium channel	0.0056	0.0182	0.0148
Mycobacterium tuberculosis	DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase)	0.0111	0.0519	1
Trichomonas vaginalis	CMGC family protein kinase	0.0066	0.0245	0.0207
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.015	0.0762	0.0726
Schistosoma mansoni	hypothetical protein	0.0065	0.0242	0.0216
Brugia malayi	Protein kinase domain containing protein	0.0194	0.1031	0.0996
Brugia malayi	Inhibitor of Apoptosis domain containing protein	0.0065	0.0242	0.0204
Leishmania major	protein kinase, putative,dual-specificity protein kinase, putative	0.0232	0.1265	0.1265
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Echinococcus granulosus	DNA topoisomerase 2 alpha	0.0032	0.0039	0.0005
Brugia malayi	cell division control protein 2 homolog	0.0066	0.0245	0.0207
Trichomonas vaginalis	CMGC family protein kinase	0.0232	0.1265	0.1231
Trypanosoma cruzi	mitochondrial DNA topoisomerase II, putative	0.0032	0.0039	0.0039
Trypanosoma cruzi	cdc2-related kinase 1	0.0066	0.0245	0.0245
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0066	0.0245	0.0207
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0038	0.0074	0.0035
Echinococcus granulosus	casein kinase ii subunit beta	0.015	0.0762	0.073
Loa Loa (eye worm)	Csnk2b protein	0.015	0.0762	0.0726
Mycobacterium leprae	Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase)	0.0053	0.0165	0.5
Loa Loa (eye worm)	CMGC/DYRK/HIPK protein kinase	0.0703	0.4145	0.4122
Leishmania major	glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270	0.0071	0.0279	0.0279
Echinococcus multilocularis	inhibitor of apoptosis protein	0.0065	0.0242	0.0208
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0044	0.0112	0.0078
Wolbachia endosymbiont of Brugia malayi	DNA gyrase subunit A	0.0111	0.0519	1
Brugia malayi	casein kinase II, putaitve	0.0044	0.011	0.0072
Entamoeba histolytica	protein kinase domain containing protein	0.1658	1	1
Plasmodium falciparum	casein kinase 2, alpha subunit	0.1658	1	1
Schistosoma mansoni	casein kinase II beta subunit	0.015	0.0762	0.0737
Toxoplasma gondii	ck2 beta subunit	0.015	0.0762	0.0726
Schistosoma mansoni	inhibitor of apoptosis (iap) domain family member	0.0065	0.0242	0.0216
Trypanosoma brucei	Casein kinase II subunit beta, putative	0.015	0.0762	0.0762
Trichomonas vaginalis	CMGC family protein kinase	0.0232	0.1265	0.1231
Schistosoma mansoni	serine/threonine protein kinase	0.0703	0.4145	0.4129
Trypanosoma cruzi	mitochondrial DNA topoisomerase II, putative	0.0032	0.0039	0.0039
Entamoeba histolytica	protein kinase, putative	0.0232	0.1265	0.1231
Trypanosoma cruzi	casein kinase II, putative	0.1658	1	1
Onchocerca volvulus		0.0071	0.0279	0.2416
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0038	0.0074	0.004
Trichomonas vaginalis	CMGC family protein kinase	0.1658	1	1
Toxoplasma gondii	protein kinase G AGC kinase family member PKG	0.0044	0.0112	0.0074
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0038	0.0074	0.0035
Trichomonas vaginalis	CMGC family protein kinase	0.0066	0.0245	0.0207
Echinococcus granulosus	homeodomain interacting protein kinase 3	0.0703	0.4145	0.4125
Plasmodium vivax	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Trypanosoma brucei	dual specificity tyrosine-phosphorylation-regulated kinase 2, putative	0.0232	0.1265	0.1265
Echinococcus granulosus	dual specificity	0.0232	0.1265	0.1235
Echinococcus multilocularis	DNA topoisomerase 2 alpha	0.0032	0.0039	0.0005
Treponema pallidum	DNA gyrase, subunit A (gyrA)	0.0111	0.0519	1
Brugia malayi	Homeodomain interacting protein kinase protein 1	0.0703	0.4145	0.4122
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0038	0.0074	0.0047
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Trichomonas vaginalis	CMGC family protein kinase	0.1658	1	1
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0056	0.0182	0.0148
Echinococcus granulosus	dual specificity	0.0193	0.1026	0.0995
Giardia lamblia	Casein kinase II beta chain	0.015	0.0762	0.0742
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0066	0.0245	0.0207
Trypanosoma brucei	protein kinase, putative	0.0071	0.0279	0.0279
Echinococcus multilocularis	potassium:sodium hyperpolarization activated	0.0038	0.0074	0.004
Plasmodium falciparum	DNA gyrase subunit B	0.0058	0.0198	0.016
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0242	0.0204
Trypanosoma brucei	cdc2-related kinase 1	0.0066	0.0245	0.0245
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Schistosoma mansoni	serine/threonine protein kinase	0.0066	0.0245	0.0219
Loa Loa (eye worm)	CMGC/CDK/CDK5 protein kinase	0.0066	0.0245	0.0207
Echinococcus granulosus	cyclin dependent kinase	0.0066	0.0245	0.0212
Giardia lamblia	Kinase, CMGC GSK	0.0071	0.0279	0.0257
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0044	0.0112	0.0078
Brugia malayi	Csnk2b protein	0.015	0.0762	0.0726
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0179	0.0939	0.0904
Plasmodium vivax	casein kinase 2, alpha subunit, putative	0.1658	1	1
Toxoplasma gondii	cell-cycle-associated protein kinase GSK, putative	0.0071	0.0279	0.0241
Entamoeba histolytica	cell division protein kinase 2, putative	0.0066	0.0245	0.0207
Plasmodium vivax	DNA gyrase subunit B, putative	0.0058	0.0198	0.016
Trypanosoma cruzi	dual specificity tyrosine-phosphorylation-regulated kinase 2, putative	0.0232	0.1265	0.1265
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0038	0.0074	0.0047
Entamoeba histolytica	protein kinase, putative	0.0071	0.0279	0.0241
Entamoeba histolytica	protein kinase domain containing protein	0.0232	0.1265	0.1231
Trypanosoma cruzi	Casein kinase II subunit beta, putative	0.015	0.0762	0.0762
Schistosoma mansoni	voltage-gated potassium channel	0.0056	0.0182	0.0156
Brugia malayi	Protein kinase domain containing protein	0.0193	0.1026	0.0991
Plasmodium vivax	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Echinococcus granulosus	cyclic nucleotide gated cation channel alpha 3	0.0038	0.0074	0.004
Echinococcus multilocularis	voltage gated potassium channel	0.0056	0.0182	0.0148
Echinococcus granulosus	hyperpolarization activated cyclic	0.0038	0.0074	0.004
Onchocerca volvulus		0.0065	0.0242	0.2047
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0038	0.0074	0.004
Trichomonas vaginalis	CMGC family protein kinase	0.0232	0.1265	0.1231
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0038	0.0074	0.004
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.015	0.0762	0.0726
Echinococcus multilocularis	cyclin dependent kinase	0.0066	0.0245	0.0212
Echinococcus multilocularis	casein kinase ii subunit alpha	0.1658	1	1
Leishmania major	cell division related protein kinase 2,cdc2-related kinase	0.0066	0.0245	0.0245
Leishmania major	cell division protein kinase 2,cdc2-related kinase	0.0066	0.0245	0.0245
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Schistosoma mansoni	DNA topoisomerase II	0.0032	0.0039	0.0012
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trichomonas vaginalis	CMGC family protein kinase	0.0071	0.0279	0.0241
Chlamydia trachomatis	DNA gyrase subunit A	0.0111	0.0519	1
Loa Loa (eye worm)	AGC/PKG protein kinase	0.0044	0.0112	0.0074
Plasmodium falciparum	protein kinase 5	0.0066	0.0245	0.0207
Schistosoma mansoni	serine/threonine protein kinase	0.0232	0.1265	0.1242
Leishmania major	protein kinase ck2 regulatory subunit, putative	0.015	0.0762	0.0762
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0182	0.0144
Brugia malayi	Cyclic-nucleotide gated cation channel	0.0038	0.0074	0.0035
Entamoeba histolytica	protein kinase, putative	0.0193	0.1026	0.0991
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Toxoplasma gondii	cell-cycle-associated protein kinase DYRK2, putative	0.0232	0.1265	0.1231
Trypanosoma brucei	Casein kinase II	0.1658	1	1
Brugia malayi	Serine/threonine-protein kinase Pim-3	0.0194	0.1031	0.0996
Echinococcus multilocularis	cGMP dependent protein kinase 1	0.0044	0.0112	0.0078
Plasmodium vivax	DNA gyrase subunit A, putative	0.0111	0.0519	0.0482
Toxoplasma gondii	DNA gyrase/topoisomerase IV, A subunit domain-containing protein	0.0111	0.0519	0.0482
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0044	0.011	0.0072
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0192	0.1016	0.0985
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Trypanosoma cruzi	CMGC/DYRK protein kinase, putative	0.0193	0.1026	0.1026
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0074	0.0035
Leishmania major	mitochondrial DNA topoisomerase II	0.0032	0.0039	0.0039
Echinococcus granulosus	dual specificity	0.0232	0.1265	0.1235
Schistosoma mansoni	serine/threonine protein kinase	0.0066	0.0245	0.0219
Loa Loa (eye worm)	casein kinase II	0.0044	0.011	0.0072
Trypanosoma brucei	STE group serine/threonine-protein kinase, putative	0.0036	0.0065	0.0065
Trypanosoma cruzi	Casein kinase II subunit beta, putative	0.015	0.0762	0.0762
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0056	0.0182	0.0144
Schistosoma mansoni	voltage-gated potassium channel	0.0209	0.1124	0.11
Echinococcus granulosus	hyperpolarization activated cyclic	0.0038	0.0074	0.004
Brugia malayi	Inhibitor of Apoptosis domain containing protein	0.0065	0.0242	0.0204
Giardia lamblia	Kinase, CMGC DYRK	0.0232	0.1265	0.1246
Trichomonas vaginalis	CMGC family protein kinase	0.0232	0.1265	0.1231
Trichomonas vaginalis	CMGC family protein kinase	0.0232	0.1265	0.1231
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Entamoeba histolytica	hypothetical protein	0.0193	0.1026	0.0991
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0192	0.1016	0.0981
Plasmodium falciparum	casein kinase II beta chain	0.015	0.0762	0.0726
Trypanosoma brucei	CMGC/DYRK protein kinase, putative	0.0193	0.1026	0.1026
Leishmania major	protein kinase, putative	0.0044	0.0112	0.0112
Giardia lamblia	Kinase, CMGC CK2	0.1658	1	1
Onchocerca volvulus	Deterin homolog	0.0065	0.0242	0.2047
Trypanosoma cruzi	glycogen synthase kinase 3, putative	0.0071	0.0279	0.0279
Echinococcus multilocularis	protein kinase shaggy	0.0071	0.0279	0.0245
Mycobacterium ulcerans	DNA gyrase subunit A	0.0111	0.0519	1
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0056	0.0182	0.0148
Echinococcus multilocularis	homeodomain interacting protein kinase 3	0.0703	0.4145	0.4125
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Loa Loa (eye worm)	CAMK/PIM protein kinase	0.0194	0.1031	0.0996
Loa Loa (eye worm)	hypothetical protein	0.0175	0.0911	0.0875
Leishmania major	casein kinase II, putative	0.1658	1	1
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0192	0.1016	0.0985
Toxoplasma gondii	CMGC kinase, CK2 family	0.1658	1	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trypanosoma brucei	cdc2-related kinase 3	0.0066	0.0245	0.0245
Brugia malayi	Protein kinase domain containing protein	0.0066	0.0245	0.0207
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Echinococcus granulosus	cyclin dependent kinase 1	0.0066	0.0245	0.0212
Echinococcus granulosus	protein kinase shaggy	0.0071	0.0279	0.0245
Echinococcus multilocularis	cyclic nucleotide gated cation channel alpha 3	0.0038	0.0074	0.004
Echinococcus granulosus	glycogen synthase kinase 3 beta	0.0071	0.0279	0.0245
Brugia malayi	intracellular kinase	0.0071	0.0279	0.0241
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0038	0.0074	0.0047
Schistosoma mansoni	glycogen synthase kinase 3-related (gsk3) (cmgc group III)	0.0071	0.0279	0.0253
Leishmania major	protein kinase, putative	0.0044	0.0112	0.0112
Leishmania major	serine/threonine-protein kinase, putative,protein kinase, putative	0.0193	0.1026	0.1026
Plasmodium falciparum	glycogen synthase kinase 3	0.0071	0.0279	0.0241
Echinococcus multilocularis	cyclin dependent kinase 1	0.0066	0.0245	0.0212
Trichomonas vaginalis	CMGC family protein kinase	0.1658	1	1
Echinococcus multilocularis	cyclin dependent kinase 1	0.0066	0.0245	0.0212
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0038	0.0074	0.0035
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Echinococcus multilocularis	cGMP dependent protein kinase 1	0.0044	0.0112	0.0078
Echinococcus multilocularis	dual specificity	0.0232	0.1265	0.1235
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0044	0.011	0.0072
Echinococcus multilocularis	proto oncogene serine:threonine protein kinase	0.0194	0.1031	0.1
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0038	0.0074	0.0035
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.015	0.0762	0.0726
Trypanosoma cruzi	cdc2-related kinase 3	0.0066	0.0245	0.0245
Loa Loa (eye worm)	hypothetical protein	0.0166	0.0861	0.0825
Trypanosoma brucei	DNA topoisomerase ii	0.0032	0.0039	0.0039
Schistosoma mansoni	protein kinase	0.1658	1	1
Loa Loa (eye worm)	CMGC/DYRK/DYRK2 protein kinase	0.0232	0.1265	0.1231
Brugia malayi	Dual-specificity tyrosine-phosphorylation regulated kinase 2	0.0232	0.1265	0.1231
Loa Loa (eye worm)	hypothetical protein	0.0175	0.0911	0.0875
Echinococcus multilocularis	expressed conserved protein	0.0044	0.0112	0.0078
Entamoeba histolytica	casein kinase, putative	0.1658	1	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Loa Loa (eye worm)	CMGC/CK2 protein kinase	0.1658	1	1
Echinococcus granulosus	cyclin dependent kinase 5	0.0066	0.0245	0.0212
Echinococcus multilocularis	dual specificity	0.0232	0.1265	0.1235
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0038	0.0074	0.0047
Giardia lamblia	Kinase, CMGC CDK	0.0066	0.0245	0.0224
Plasmodium falciparum	cGMP-dependent protein kinase	0.0044	0.0112	0.0074
Entamoeba histolytica	protein kinase, putative	0.0193	0.1026	0.0991
Entamoeba histolytica	protein kinase domain containing protein	0.0071	0.0279	0.0241
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Schistosoma mansoni	serine/threonine protein kinase	0.0044	0.0112	0.0086
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Plasmodium vivax	protein kinase Crk2	0.0066	0.0245	0.0207
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Schistosoma mansoni	serine/threonine protein kinase	0.0193	0.1026	0.1002
Echinococcus multilocularis	dual specificity	0.0232	0.1265	0.1235
Echinococcus granulosus	5'partial\|cyclin dependent kinase 1	0.0066	0.0245	0.0212
Entamoeba histolytica	protein kinase domain containing protein	0.0193	0.1026	0.0991
Echinococcus multilocularis	cyclic nucleotide gated cation channel	0.0038	0.0074	0.004
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0179	0.0939	0.0904
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0242	0.0204
Echinococcus granulosus	cGMP dependent protein kinase	0.0044	0.0112	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0047	0.013	0.0091
Echinococcus granulosus	casein kinase ii subunit alpha	0.1658	1	1
Trypanosoma cruzi	CMGC/DYRK protein kinase, putative	0.0193	0.1026	0.1026
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Echinococcus granulosus	potassium:sodium hyperpolarization activated	0.0038	0.0074	0.004
Echinococcus multilocularis	glycogen synthase kinase 3 beta	0.0071	0.0279	0.0245
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0192	0.1016	0.0981
Toxoplasma gondii	casein kinase ii regulatory subunit protein	0.015	0.0762	0.0726
Trichomonas vaginalis	CMGC family protein kinase	0.1658	1	1
Loa Loa (eye worm)	CAMK/PIM protein kinase	0.0194	0.1031	0.0996
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Brugia malayi	Egg laying defective protein 4	0.0044	0.0112	0.0074
Echinococcus granulosus	death associated protein kinase 1	0.0586	0.343	0.3408
Plasmodium vivax	glycogen synthase kinase 3, putative	0.0071	0.0279	0.0241
Giardia lamblia	Casein kinase II beta chain	0.0044	0.011	0.0089
Giardia lamblia	Kinase, CMGC CDK	0.0066	0.0245	0.0224
Trichomonas vaginalis	CMGC family protein kinase	0.1658	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0071	0.0279	0.0241
Giardia lamblia	Kinase, CMGC GSK	0.0071	0.0279	0.0257
Echinococcus granulosus	proto oncogene serine:threonine protein kinase	0.0194	0.1031	0.1
Echinococcus multilocularis	death associated protein kinase 1	0.0816	0.4839	0.4821
Echinococcus multilocularis	dual specificity	0.0193	0.1026	0.0995
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0038	0.0074	0.004
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0071	0.0279	0.0241
Echinococcus multilocularis	casein kinase ii subunit beta	0.015	0.0762	0.073
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trypanosoma cruzi	cdc2-related kinase 1	0.0066	0.0245	0.0245
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Echinococcus granulosus	baculoviral IAP repeat containing protein	0.0065	0.0242	0.0208
Trichomonas vaginalis	protein kinase ck2-beta, putative	0.0044	0.011	0.0072
Trichomonas vaginalis	CMGC family protein kinase	0.1658	1	1
Toxoplasma gondii	cell-cycle-associated protein kinase CDK, putative	0.0066	0.0245	0.0207
Onchocerca volvulus	Serine\/threonine protein kinase homolog	0.0194	0.1031	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0044	0.011	0.0072
Trichomonas vaginalis	CMGC family protein kinase	0.0066	0.0245	0.0207
Trichomonas vaginalis	casein kinase II beta chain, putative	0.015	0.0762	0.0726
Plasmodium vivax	unspecified product	0.1658	1	1
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0071	0.0279	0.0241

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1624762

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1470021