Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | chemokine (C-C motif) receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | notch | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0768 | 0.0768 |
Brugia malayi | Muscle positioning protein 4 | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | slit | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | slit 2 protein | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | neural cadherin | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Echinococcus granulosus | delta-like protein 1 | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | septate junction protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Giardia lamblia | High cysteine protein | 0.0055 | 0.2631 | 0.5 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | notch-like transmembrane receptor | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0055 | 0.2631 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0768 | 0.0768 |
Echinococcus granulosus | notch | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0768 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | protein jagged 2 | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0768 | 0.0768 |
Echinococcus granulosus | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Delta serrate ligand family protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | neural cadherin | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0738 | 0.0738 |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0055 | 0.2631 | 0.2018 |
Onchocerca volvulus | Putative cubilin | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | Notch2 | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Onchocerca volvulus | Slit protein homolog | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | cell polarity protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0768 | 0.0768 |
Echinococcus multilocularis | fibropellin Ia | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | notch protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Cadherin domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | slit 2 protein | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | fibropellin Ia | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | protein jagged 2 | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Cadherin domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | protein jagged 2 | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.