Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | chemokine (C-C motif) receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Putative cubilin | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | fibropellin Ia | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0768 | 0.0768 |
Brugia malayi | Cadherin domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0768 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0738 | 0.0738 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | slit | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0768 | 0.0768 |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | notch-like transmembrane receptor | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | slit 2 protein | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | fibropellin Ia | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | notch | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Delta serrate ligand family protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | neural cadherin | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Onchocerca volvulus | Slit protein homolog | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | notch | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0768 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0768 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | notch protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus granulosus | delta-like protein 1 | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | protein jagged 2 | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | septate junction protein | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | Notch2 | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Giardia lamblia | High cysteine protein | 0.0055 | 0.2631 | 0.5 |
Onchocerca volvulus | 0.0055 | 0.2631 | 0.2018 | |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | EGF-like domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0055 | 0.2631 | 0.2018 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0055 | 0.2631 | 0.5 |
Echinococcus granulosus | protein jagged 2 | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | neural cadherin | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | notch | 0.0055 | 0.2631 | 0.2018 |
Echinococcus granulosus | slit 2 protein | 0.0055 | 0.2631 | 0.2018 |
Schistosoma mansoni | cell polarity protein | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Muscle positioning protein 4 | 0.0055 | 0.2631 | 0.2631 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Echinococcus multilocularis | protein jagged 1 | 0.0055 | 0.2631 | 0.2018 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.2631 | 0.2018 |
Echinococcus multilocularis | protein jagged 2 | 0.0055 | 0.2631 | 0.2018 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2631 | 0.2631 |
Brugia malayi | Cadherin domain containing protein | 0.0055 | 0.2631 | 0.2631 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.