Detailed information for compound 158625

Basic information

Technical information
  • TDR Targets ID: 158625
  • Name: (2S,3S,4S)-2-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5 -(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-methox yoxolan-2-yl]-2-oxoethoxy]-N-[2-(3,4-dimethox yphenyl)ethyl]-3,4-dihydroxy-3,4-dihydro-2H-p yran-6-carboxamide
  • MW: 622.578 | Formula: C27H34N4O13
  • H donors: 6 H acceptors: 7 LogP: -2.41 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 3
  • SMILES: CO[C@@H]1[C@H](O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O)[C@H](C(=O)N)O[C@H]1OC(=C[C@@H]([C@@H]1O)O)C(=O)NCCc1ccc(c(c1)OC)OC
  • InChi: 1S/C27H34N4O13/c1-39-14-5-4-12(10-15(14)40-2)6-8-29-24(37)16-11-13(32)18(34)26(42-16)44-22(23(28)36)21-20(41-3)19(35)25(43-21)31-9-7-17(33)30-27(31)38/h4-5,7,9-11,13,18-22,25-26,32,34-35H,6,8H2,1-3H3,(H2,28,36)(H,29,37)(H,30,33,38)/t13-,18-,19+,20-,21-,22+,25+,26+/m0/s1
  • InChiKey: QYLGUXRTVGQUJV-XROQQFDASA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S,3S,4S)-2-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-methoxy-tetrahydrofuran-2-yl]-2-oxo-ethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxamide
  • (2S,3S,4S)-2-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxo-1-pyrimidinyl)-4-hydroxy-3-methoxy-2-tetrahydrofuranyl]-2-oxoethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxamide
  • (2S,3S,4S)-2-[(1R)-2-azanyl-1-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-methoxy-oxolan-2-yl]-2-oxo-ethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxamide
  • (2S,3S,4S)-2-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-diketopyrimidin-1-yl)-4-hydroxy-3-methoxy-tetrahydrofuran-2-yl]-2-keto-ethoxy]-N-homoveratryl-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxamide
  • (4S,5S,6S)-6-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-methoxyoxolan-2-yl]-2-oxoethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxamide
  • (4S,5S,6S)-6-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-methoxy-tetrahydrofuran-2-yl]-2-oxo-ethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxamide
  • (4S,5S,6S)-6-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxo-1-pyrimidinyl)-4-hydroxy-3-methoxy-2-tetrahydrofuranyl]-2-oxoethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxamide
  • (4S,5S,6S)-6-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-diketopyrimidin-1-yl)-4-hydroxy-3-methoxy-tetrahydrofuran-2-yl]-2-keto-ethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxamide
  • (4S,5S,6S)-6-[(1R)-2-amino-1-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-3-methoxy-oxolan-2-yl]-2-oxo-ethoxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxamide
  • (4S,5S,6S)-6-{(R)-1-Carbamoyl-1-[(2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-hydroxy-3-methoxy-tetrahydro-furan-2-yl]-methoxy}-4,5-dihydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid [2-(3,4-dimethoxy-phenyl)-ethyl]-amide
  • AIDS-189134
  • AIDS189134

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli phospho-N-acetylmuramoyl-pentapeptide transferase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX Get druggable targets OG5_131597 All targets in OG5_131597
Mycobacterium leprae Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX Get druggable targets OG5_131597 All targets in OG5_131597
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) Get druggable targets OG5_131597 All targets in OG5_131597
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase Get druggable targets OG5_131597 All targets in OG5_131597
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase Get druggable targets OG5_131597 All targets in OG5_131597
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase Get druggable targets OG5_131597 All targets in OG5_131597
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0038 0.027 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0215 0.0861
Leishmania major hypothetical protein, conserved 0.0034 0.0227 0.6201
Schistosoma mansoni hypothetical protein 0.0051 0.0422 0.1816
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0023 0.0101 0.1222
Schistosoma mansoni glutaminase 0.0208 0.2197 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0215 0.3135
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0227 0.079
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0023 0.0101 0.0336
Loa Loa (eye worm) glutaminase 2 0.0208 0.2197 0.8611
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0215 0.6657
Onchocerca volvulus 0.0038 0.027 0.095
Brugia malayi latrophilin 2 splice variant baaae 0.011 0.1093 0.4227
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.007 0.0715
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0422 0.661
Plasmodium falciparum UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0038 0.027 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0215 0.3135
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0624 0.2366
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0215 0.3135
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.007 0.0169
Schistosoma mansoni DNA polymerase eta 0.002 0.007 0.0196
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0215 0.5724
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0322 0.1358
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0322 0.1185
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0023 0.0101 0.1222
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0227 0.6201
Loa Loa (eye worm) hypothetical protein 0.011 0.1093 0.4227
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0227 0.2178
Trichomonas vaginalis glutaminase, putative 0.0208 0.2197 1
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0624 0.2747
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0215 0.5724
Giardia lamblia Kinase, CMGC MAPK 0.0042 0.0322 1
Mycobacterium ulcerans glutaminase 0.0208 0.2197 0.2142
Toxoplasma gondii glycosyl transferase, group 4 family protein 0.0038 0.027 0.7634
Leishmania major UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0038 0.027 0.7917
Loa Loa (eye worm) hypothetical protein 0.0038 0.027 0.0961
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0322 0.1185
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.007 0.0196
Echinococcus granulosus mitogen activated protein kinase 3 0.0042 0.0322 0.4944
Echinococcus granulosus tar DNA binding protein 0.0069 0.0624 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0215 0.5724
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0022 0.0091 0.1063
Trichomonas vaginalis set domain proteins, putative 0.018 0.1883 0.8523
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0422 0.661
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0215 0.0145
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0624 0.2747
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0038 0.027 0.1116
Echinococcus multilocularis dna polymerase eta 0.002 0.007 0.0715
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0227 0.3337
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0038 0.027 0.1116
Loa Loa (eye worm) hypothetical protein 0.0023 0.0101 0.0289
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.007 0.0715
Trypanosoma brucei protein kinase, putative 0.0042 0.0322 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0624 0.2747
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0322 0.1185
Trypanosoma brucei unspecified product 0.002 0.007 0.2183
Trypanosoma brucei UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0038 0.027 0.8372
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.007 0.2183
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0227 0.3337
Echinococcus granulosus UDP N acetylglucosamine dolichyl phosphate 0.0038 0.027 0.4063
Echinococcus granulosus dna polymerase eta 0.002 0.007 0.0715
Loa Loa (eye worm) hypothetical protein 0.0051 0.0422 0.1564
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.2547 1
Brugia malayi Augmenter of liver regeneration 0.0034 0.0227 0.079
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0227 0.6201
Brugia malayi follicle stimulating hormone receptor 0.0176 0.1838 0.7184
Echinococcus multilocularis GPCR, family 2 0.0051 0.0422 0.661
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0422 0.1564
Echinococcus multilocularis mitogen activated protein kinase 3 0.0042 0.0322 0.4944
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0215 0.0742
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.007 0.0196
Trichomonas vaginalis glucosaminephosphotransferase, putative 0.0038 0.027 0.0938
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0624 1
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.007 0.2183
Echinococcus multilocularis dna polymerase kappa 0.002 0.007 0.0715
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.007 0.0169
Brugia malayi MH2 domain containing protein 0.0239 0.2547 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0023 0.0101 0.1222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.0101 0.0336
Echinococcus multilocularis mitogen activated protein kinase 0.0042 0.0322 0.4944
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0042 0.0322 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0042 0.0322 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0042 0.0322 0.117
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0215 0.3135
Loa Loa (eye worm) hypothetical protein 0.0161 0.1671 0.6522
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Schistosoma mansoni hypothetical protein 0.0051 0.0422 0.1816
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0042 0.0322 1
Schistosoma mansoni hypothetical protein 0.0051 0.0422 0.1816
Brugia malayi Pre-SET motif family protein 0.0158 0.1636 0.6381
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0042 0.0322 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0161 0.1671 0.6522
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0161 0.1671 0.6522
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0422 0.1564
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.007 0.2183
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0042 0.0322 1
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0624 0.2747
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0896 1 1
Loa Loa (eye worm) hypothetical protein 0.002 0.007 0.0169
Echinococcus granulosus mitogen activated protein kinase 0.0042 0.0322 0.4944
Echinococcus multilocularis UDP N acetylglucosamine dolichyl phosphate 0.0038 0.027 0.4063
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0624 0.2747
Brugia malayi isocitrate dehydrogenase 0.0033 0.0215 0.0742
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0215 0.6657
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0042 0.0322 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0227 0.6201
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0422 0.1564
Brugia malayi Pre-SET motif family protein 0.0023 0.0101 0.0289
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.007 0.2183
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0215 0.0742
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0042 0.0322 1
Giardia lamblia UDP-N-acetylglucosamine-dolichyl-phosphateN-acetylglucosaminephosphotransferase 0.0038 0.027 0.7917
Brugia malayi TAR-binding protein 0.0069 0.0624 0.2366
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0215 0.5141
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0227 0.7031
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0215 0.3135
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Brugia malayi MAP kinase sur-1 0.0042 0.0322 0.117
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0341 0.3704 0.5
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0896 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.2547 1
Onchocerca volvulus 0.018 0.1883 1
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0227 0.5684
Loa Loa (eye worm) glutaminase 0.0208 0.2197 0.8611
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0215 0.5141
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.0101 0.0336
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0042 0.0322 1
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0227 0.7446
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0038 0.027 0.7917
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) 0.0341 0.3704 0.5
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0624 0.2366
Echinococcus granulosus GPCR family 2 0.0051 0.0422 0.661
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0422 0.661
Loa Loa (eye worm) RNA binding protein 0.0069 0.0624 0.2366
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0158 0.1636 0.6381
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0038 0.027 0.7917
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0896 1 0.5
Brugia malayi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0038 0.027 0.0961
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0624 0.2366
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0322 0.1185
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0023 0.0101 0.0336
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0422 0.661
Mycobacterium ulcerans undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe 0.0038 0.027 0.0201
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0161 0.1671 0.6522
Plasmodium vivax N-acetylglucosamine-1-phosphate transferase, putative 0.0038 0.027 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0176 0.1838 0.7184
Brugia malayi glutaminase DH11.1 0.0208 0.2197 0.8611
Brugia malayi RNA binding protein 0.0069 0.0624 0.2366
Echinococcus granulosus dna polymerase kappa 0.002 0.007 0.0715
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0227 0.5684
Schistosoma mansoni hypothetical protein 0.011 0.1093 0.4909
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.007 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.007 0.2183
Schistosoma mansoni hypothetical protein 0.0051 0.0422 0.1816
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0215 0.3135
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0215 0.6735

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 25 ng ml-1 Inhibitory activity against translocase I ChEMBL. 14611838
IC50 (binding) = 25 ng ml-1 Inhibitory activity against translocase I ChEMBL. 14611838
MIC (functional) = 50 ug ml-1 Antimycobacterial activity against Mycobacterium smegmatis (SANK 75075) ChEMBL. 14611838

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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