Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | non-specific serine/threonine protein kinase | 0.009 | 0.1634 | 0.2153 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.034 | 0.784 | 0.7822 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0045 | 0.0524 | 0.0443 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0143 | 0.2955 | 0.2895 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0427 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0081 | 0.1405 | 0.1332 |
Entamoeba histolytica | phosphatidylinositol-4,5-bisphosphate 3-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0143 | 0.2955 | 0.2895 |
Leishmania major | hypothetical protein, unknown function | 0.0028 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0151 | 0.3158 | 0.3158 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.059 | 0.0509 |
Plasmodium vivax | protein kinase Crk2 | 0.0045 | 0.0524 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0151 | 0.3158 | 0.3158 |
Toxoplasma gondii | FATC domain-containing protein | 0.0081 | 0.1405 | 0.1835 |
Loa Loa (eye worm) | phosphatidylinositol kinase | 0.0028 | 0.0085 | 0.0085 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.059 | 0.059 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.059 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0085 | 0.0085 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0427 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0143 | 0.2955 | 0.2895 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0143 | 0.2955 | 0.2895 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0143 | 0.2955 | 0.2895 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0255 | 0.5734 | 0.5698 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0151 | 0.3158 | 0.3158 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0045 | 0.0524 | 0.0443 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0427 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.009 | 0.1634 | 0.1563 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0045 | 0.0524 | 0.0524 |
Leishmania major | cytochrome p450-like protein | 0.0028 | 0.0088 | 0.0088 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0253 | 0.5671 | 0.5634 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0045 | 0.0524 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.059 | 0.059 |
Brugia malayi | FAT domain containing protein | 0.0062 | 0.0951 | 0.0951 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.023 | 0.5115 | 0.5074 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0045 | 0.0524 | 0.0524 |
Echinococcus granulosus | serine:threonine protein kinase SMG1 | 0.0081 | 0.1405 | 0.1332 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0081 | 0.1405 | 0.1405 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0255 | 0.5734 | 0.5698 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0045 | 0.0524 | 0.061 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.034 | 0.7831 | 0.7813 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0722 | 0.0722 |
Onchocerca volvulus | 0.0028 | 0.0085 | 1 | |
Loa Loa (eye worm) | CYP4Cod1 | 0.0028 | 0.0088 | 0.0088 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0081 | 0.1405 | 0.1332 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0028 | 0.0085 | 0.0085 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.034 | 0.7831 | 0.7813 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0053 | 0.0722 | 0.0642 |
Echinococcus granulosus | serine protein kinase ATM | 0.0081 | 0.1405 | 0.1332 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0231 | 0.5124 | 0.5082 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0062 | 0.0951 | 0.0873 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.1405 | 0.1405 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0427 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0318 | 0.7284 | 0.7261 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.059 | 0.0509 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0028 | 0.0085 | 0.0085 |
Echinococcus granulosus | cyclin dependent kinase | 0.0045 | 0.0524 | 0.0443 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0103 | 0.1969 | 0.1969 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0115 | 0.2245 | 0.2178 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0045 | 0.0524 | 0.0443 |
Leishmania major | phosphatidylinositol 4-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0028 | 0.0085 | 0.0085 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0045 | 0.0524 | 0.0443 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0427 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0045 | 0.0524 | 0.0443 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0318 | 0.7284 | 0.7261 |
Brugia malayi | Cytochrome P450 family protein | 0.0063 | 0.0969 | 0.0969 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0231 | 0.5124 | 0.5082 |
Brugia malayi | Cytochrome P450 family protein | 0.0028 | 0.0088 | 0.0088 |
Entamoeba histolytica | protein kinase rad3, putative | 0.0081 | 0.1405 | 0.1405 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0143 | 0.2955 | 0.2895 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0231 | 0.5124 | 0.5082 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1405 | 0.1405 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.034 | 0.7831 | 0.7813 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0045 | 0.0524 | 0.0443 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0045 | 0.0524 | 0.0524 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0045 | 0.0524 | 0.0524 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0143 | 0.2955 | 0.2955 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0427 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0045 | 0.0524 | 0.0443 |
Plasmodium falciparum | protein kinase 5 | 0.0045 | 0.0524 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0045 | 0.0524 | 0.0443 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0365 | 0.845 | 0.8437 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.034 | 0.7831 | 0.7813 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0045 | 0.0524 | 0.0524 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0202 | 0.4413 | 0.4366 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0045 | 0.0524 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.059 | 0.0509 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0085 | 0.0085 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.059 | 0.0509 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.059 | 0.059 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0143 | 0.2955 | 0.2955 |
Schistosoma mansoni | hypothetical protein | 0.0103 | 0.1969 | 0.1901 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0427 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0045 | 0.0524 | 0.0443 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0427 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0028 | 0.0088 | 0.0088 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0253 | 0.5671 | 0.5634 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0045 | 0.0524 | 0.0524 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0143 | 0.2955 | 0.2955 |
Schistosoma mansoni | fkbp-rapamycin associated protein | 0.0081 | 0.1405 | 0.1332 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0277 | 0.6281 | 0.625 |
Echinococcus multilocularis | PIK kinase, FAT and Armadillo domain containing protein | 0.0062 | 0.0951 | 0.0873 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.2418 | 0.2418 |
Giardia lamblia | Kinase, CMGC CDK | 0.0045 | 0.0524 | 0.0443 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0028 | 0.0088 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.059 | 0.0509 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0143 | 0.2955 | 0.2895 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0081 | 0.1405 | 0.1332 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0045 | 0.0524 | 0.0443 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0028 | 0.0085 | 0.0085 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0427 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0143 | 0.2955 | 0.2895 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0028 | 0.0085 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0028 | 0.0088 | 0.0003 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0177 | 0.3803 | 0.375 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.059 | 0.0509 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0081 | 0.1405 | 0.1332 |
Brugia malayi | Protein kinase domain containing protein | 0.0045 | 0.0524 | 0.0524 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.2418 | 0.2418 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0143 | 0.2955 | 0.2895 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0045 | 0.0524 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0045 | 0.0524 | 0.0443 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0427 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0143 | 0.2955 | 0.2895 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0143 | 0.2955 | 0.2895 |
Entamoeba histolytica | Phosphatidylinositol 3- and 4-kinase family | 0.0081 | 0.1405 | 0.1405 |
Entamoeba histolytica | phosphatidylinositol 4-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1561 | 0.1561 |
Brugia malayi | Cytochrome P450 family protein | 0.0028 | 0.0088 | 0.0088 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0028 | 0.0088 | 0.0003 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.023 | 0.5115 | 0.5074 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0427 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.034 | 0.7831 | 0.7813 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0231 | 0.5124 | 0.5082 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0063 | 0.0969 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1634 | 0.1634 |
Echinococcus granulosus | PIK kinase FAT and Armadillo domain containing protein | 0.0062 | 0.0951 | 0.0873 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.059 | 0.0509 |
Brugia malayi | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | 0.0028 | 0.0085 | 0.0085 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.059 | 0.0509 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0081 | 0.1405 | 0.1332 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0318 | 0.7284 | 0.7261 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0045 | 0.0524 | 0.0443 |
Brugia malayi | cell division control protein 2 homolog | 0.0045 | 0.0524 | 0.0524 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0951 | 0.0951 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0318 | 0.7284 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0028 | 0.0088 | 0.0088 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0028 | 0.0085 | 0.0085 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 3, putative | 0.0028 | 0.0085 | 0.0085 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.034 | 0.784 | 0.784 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0081 | 0.1405 | 0.1405 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0081 | 0.1405 | 0.1332 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0286 | 0.651 | 0.6481 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0318 | 0.7284 | 0.7261 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0081 | 0.1405 | 0.1332 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0427 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0143 | 0.2955 | 0.2895 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.2418 | 0.2418 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.0085 | 0.0085 |
Onchocerca volvulus | 0.0028 | 0.0085 | 1 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0053 | 0.0722 | 0.0642 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.059 | 0.0509 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0045 | 0.0524 | 0.0443 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.059 | 0.059 |
Leishmania major | phosphatidylinositol kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Giardia lamblia | GTOR | 0.0427 | 1 | 1 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0427 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0028 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1969 | 0.1969 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.0951 | 0.0873 |
Leishmania major | phosphatidylinositol 4-kinase alpha, putative | 0.0028 | 0.0085 | 0.0085 |
Echinococcus multilocularis | serine:threonine protein kinase SMG1 | 0.0081 | 0.1405 | 0.1332 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.0085 | 0.0085 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0053 | 0.0722 | 0.0642 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0143 | 0.2955 | 0.2955 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.034 | 0.784 | 0.7822 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0427 | 1 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0028 | 0.0085 | 0.0085 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.023 | 0.5115 | 0.5074 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0255 | 0.5734 | 0.5698 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0028 | 0.0088 | 0.0003 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0318 | 0.7284 | 0.7261 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0318 | 0.7284 | 0.7261 |
Loa Loa (eye worm) | phosphatidylinositol 4-kinase type 3 alpha isoform 1 | 0.0028 | 0.0085 | 0.0085 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0028 | 0.0085 | 0.0085 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0045 | 0.0524 | 0.0443 |
Giardia lamblia | Kinase, CMGC CDK | 0.0045 | 0.0524 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.3158 | 0.3158 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0045 | 0.0524 | 0.0524 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0028 | 0.0085 | 0.0085 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0081 | 0.1405 | 0.1332 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0318 | 0.7284 | 0.7261 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0427 | 1 | 1 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0045 | 0.0524 | 0.0443 |
Mycobacterium leprae | conserved hypothetical protein | 0.0028 | 0.0085 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.082 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.