TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 237.338 | Formula: C14H23NO2
H donors: 0 H acceptors: 1 LogP: 1.66 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: CC(/C=C/1\CCC(C1=O)CN1CCOCC1)C
InChi: 1S/C14H23NO2/c1-11(2)9-12-3-4-13(14(12)16)10-15-5-7-17-8-6-15/h9,11,13H,3-8,10H2,1-2H3/b12-9+
InChiKey: WTWDKDAPMWDNCU-FMIVXFBMSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0107	0.0495	0.0495
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0107	0.0495	0.0486
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0312	0.1761	0.1332
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0892	0.5326	0.5322
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1314	0.7921	0.7919
Entamoeba histolytica	protein kinase, putative	0.0033	0.0045	0.0013
Echinococcus granulosus	serine protein kinase ATM	0.0312	0.1761	0.1754
Schistosoma mansoni	voltage-gated potassium channel	0.0061	0.0212	0.0212
Leishmania major	phosphatidylinositol 3-related kinase, putative	0.0554	0.3247	0.2895
Plasmodium vivax	hypothetical protein	0.0107	0.0495	0.5
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.1652	1	1
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0107	0.0495	0.0486
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0107	0.0495	0.0486
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0206	0.1106	0.0642
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1228	0.7396	0.7394
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0892	0.5326	0.5322
Trypanosoma brucei	phosphatidylinositol 3-kinase catalytic subunit, putative	0.0107	0.0495	0.0452
Echinococcus granulosus	voltage gated sodium channel Nav1 alpha subunit	0.0316	0.1782	0.1775
Entamoeba histolytica	hypothetical protein	0.0312	0.1761	0.1734
Entamoeba histolytica	phosphatidylinositol-4,5-bisphosphate 3-kinase, putative	0.0107	0.0495	0.0464
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0107	0.0495	0.0628
Loa Loa (eye worm)	phosphatidylinositol 4-kinase type 3 alpha isoform 1	0.0107	0.0495	0.0486
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1314	0.7921	0.7919
Trypanosoma brucei	phosphatidylinositol 4-kinase alpha, putative	0.0107	0.0495	0.0452
Trypanosoma brucei	phosphatidylinositol 3-kinase tor, putative	0.0781	0.4645	0.462
Schistosoma mansoni	phosphatidylinositol 4-kinase type-II	0.0107	0.0495	0.0495
Echinococcus granulosus	phosphatidylinositol 3 kinase catalytic subunit	0.0107	0.0495	0.0486
Schistosoma mansoni	voltage-gated potassium channel	0.0028	0.0009	0.0009
Plasmodium falciparum	phosphatidylinositol 4-kinase	0.0107	0.0495	0.5
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0107	0.0495	0.0495
Trichomonas vaginalis	PIKK family atypical protein kinase	0.141	0.8514	0.8513
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0554	0.3247	0.3241
Plasmodium vivax	hypothetical protein, conserved	0.0107	0.0495	0.5
Plasmodium vivax	phosphatidylinositol 4-kinase, putative	0.0107	0.0495	0.5
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1652	1	1
Loa Loa (eye worm)	phosphatidylinositol 3	0.0107	0.0495	0.0486
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.1652	1	1
Giardia lamblia	GTOR	0.1652	1	1
Leishmania major	calcium channel protein, putative,ion transporter, putative	0.0316	0.1782	0.1354
Loa Loa (eye worm)	phosphatidylinositol 3	0.0107	0.0495	0.0486
Echinococcus multilocularis	phosphatidylinositol 3 and 4 kinase	0.0554	0.3247	0.3241
Echinococcus multilocularis	phosphatidylinositol 4,5 bisphosphate 3 kinase	0.0107	0.0495	0.0486
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.0045	0.0036
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0554	0.3247	0.2895
Echinococcus granulosus	PIK kinase FAT and Armadillo domain containing protein	0.0242	0.1325	0.1317
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0033	0.0045	0.0036
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0107	0.0495	0.0628
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0107	0.0495	0.0628
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1072	0.6435	0.6432
Loa Loa (eye worm)	hypothetical protein	0.0337	0.191	0.1903
Trichomonas vaginalis	conserved hypothetical protein	0.0206	0.1106	0.1098
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0031	0.003	0.0021
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0977	0.5851	0.5847
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0034	0.0051	0.0042
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0443	0.2566	0.2559
Schistosoma mansoni	phosphatidylinositol 3-kinase class	0.0107	0.0495	0.0495
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.0554	0.3247	0.3216
Brugia malayi	FAT domain containing protein	0.0242	0.1325	0.1317
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0107	0.0495	0.0495
Entamoeba histolytica	phosphatidylinositol 3-kinase 3, putative	0.0107	0.0495	0.0464
Trichomonas vaginalis	phosphatidylinositol 4-kinase, putative	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0554	0.3247	0.3241
Schistosoma mansoni	ataxia telangiectasia mutated (atm)	0.0312	0.1761	0.1761
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0554	0.3247	0.3241
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0107	0.0495	0.0452
Entamoeba histolytica	Phosphatidylinositol 3- and 4-kinase family	0.0312	0.1761	0.1734
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1314	0.7921	0.7919
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.1652	1	1
Loa Loa (eye worm)	phosphatidylinositol 3	0.0554	0.3247	0.3241
Loa Loa (eye worm)	phosphatidylinositol kinase	0.0107	0.0495	0.0486
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.1652	1	1
Loa Loa (eye worm)	hypothetical protein	0.0107	0.0495	0.0486
Entamoeba histolytica	protein kinase rad3, putative	0.0312	0.1761	0.1734
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0987	0.5911	0.5907
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0554	0.3247	0.2895
Echinococcus granulosus	phosphatidylinositol 3 and 4 kinase	0.0554	0.3247	0.3241
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0031	0.003	0.0021
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0554	0.3247	0.3241
Loa Loa (eye worm)	hypothetical protein	0.0348	0.1981	0.1973
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.1652	1	1
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.0045	0.0036
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.0107	0.0495	0.0486
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.0031	0.0033	0.0023
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0107	0.0495	0.0486
Loa Loa (eye worm)	hypothetical protein	0.0107	0.0495	0.0486
Echinococcus multilocularis		0.0107	0.0495	0.0486
Trypanosoma cruzi	target of rapamycin kinase 3	0.1315	0.7929	0.7822
Plasmodium falciparum	phosphatidylinositol 3-kinase	0.0107	0.0495	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0242	0.1325	0.1317
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0107	0.0495	0.0495
Echinococcus multilocularis	serine protein kinase ATM	0.0312	0.1761	0.1754
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0987	0.5911	0.5907
Echinococcus multilocularis	Zinc finger, PHD finger	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0206	0.1106	0.1098
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0891	0.5317	0.5313
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.0045	0.0036
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0031	0.003	0.0021
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0107	0.0495	0.0464
Schistosoma mansoni	voltage-gated potassium channel	0.0061	0.0212	0.0212
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0977	0.5851	0.5847
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0028	0.0009	0.0009
Loa Loa (eye worm)	phosphatidylinositol 3	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1228	0.7396	0.7394
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0028	0.0009	0.0009
Entamoeba histolytica	protein kinase, putative	0.0033	0.0045	0.0013
Echinococcus multilocularis	phosphatidylinositol 4 kinase alpha	0.0107	0.0495	0.0486
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.1652	1	1
Plasmodium vivax	phosphatidylinositol 3- and 4-kinase, putative	0.0107	0.0495	0.5
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0161	0.0152
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0892	0.5326	0.5322
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0107	0.0495	0.0486
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0312	0.1761	0.1754
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1314	0.7921	0.7919
Entamoeba histolytica	hypothetical protein	0.0107	0.0495	0.0464
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0034	0.0051	0.0042
Schistosoma mansoni	fkbp-rapamycin associated protein	0.0312	0.1761	0.1761
Loa Loa (eye worm)	phosphatidylinositol 3	0.0107	0.0495	0.0486
Echinococcus multilocularis	phosphatidylinositol 4 phosphate 3 kinase C2	0.0107	0.0495	0.0486
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0107	0.0495	0.0464
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0312	0.1761	0.1332
Entamoeba histolytica	hypothetical protein	0.0107	0.0495	0.0464
Echinococcus granulosus	serine:threonine protein kinase SMG1	0.0312	0.1761	0.1754
Echinococcus granulosus	voltage gated potassium channel	0.0031	0.003	0.0021
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1108	0.6655	0.6652
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1228	0.7396	0.7394
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.0045	0.0036
Echinococcus granulosus	phosphatidylinositol 4 phosphate 3 kinase C2	0.0107	0.0495	0.0486
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0028	0.0009	0.0009
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0312	0.1761	0.1754
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.1315	0.7929	0.792
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0057	0.0191	0.0182
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.0045	0.0036
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1228	0.7396	0.7394
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.1652	1	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1652	1	1
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0028	0.0009	0.0009
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0107	0.0495	0.0452
Onchocerca volvulus		0.0107	0.0495	0.5
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit gamma, putative	0.0107	0.0495	0.0486
Entamoeba histolytica	hypothetical protein	0.0107	0.0495	0.0464
Echinococcus multilocularis	sodium channel protein	0.0316	0.1782	0.1775
Onchocerca volvulus		0.0107	0.0495	0.5
Echinococcus granulosus	phosphatidylinositol 4 kinase beta	0.0107	0.0495	0.0486
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0107	0.0495	0.0486
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0107	0.0495	0.0486
Loa Loa (eye worm)	hypothetical protein	0.0312	0.1761	0.1754
Trichomonas vaginalis	conserved hypothetical protein	0.0348	0.1981	0.1973
Loa Loa (eye worm)	hypothetical protein	0.0031	0.003	0.0021
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.1652	1	1
Toxoplasma gondii	non-specific serine/threonine protein kinase	0.0348	0.1981	0.2646
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1652	1	1
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.1315	0.7929	0.7822
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0028	0.0009	0.0009
Brugia malayi	Protein kinase domain containing protein	0.0033	0.0045	0.0036
Echinococcus multilocularis	DNA dependent protein kinase catalytic subunit	0.0107	0.0495	0.0486
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0107	0.0495	0.0464
Echinococcus multilocularis	PIK kinase, FAT and Armadillo domain containing protein	0.0242	0.1325	0.1317
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0312	0.1761	0.1754
Mycobacterium leprae	conserved hypothetical protein	0.0107	0.0495	0.5
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0057	0.0191	0.0182
Toxoplasma gondii	FATC domain-containing protein	0.0312	0.1761	0.2348
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1228	0.7396	0.7394
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0107	0.0495	0.0486
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.0107	0.0495	0.0486
Schistosoma mansoni	phosphatidylinositol 3-and 4-kinase	0.0554	0.3247	0.3247
Loa Loa (eye worm)	phosphatidylinositol 3	0.1652	1	1
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0107	0.0495	0.0464
Plasmodium falciparum	phosphatidylinositol 3- and 4-kinase, putative	0.0107	0.0495	0.5
Plasmodium vivax	phosphatidylinositol 3-kinase, putative	0.0107	0.0495	0.5
Schistosoma mansoni	hypothetical protein	0.0107	0.0495	0.0495
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0107	0.0495	0.0486
Toxoplasma gondii	target of rapamycin (TOR), putative	0.1228	0.7396	1
Entamoeba histolytica	hypothetical protein	0.0107	0.0495	0.0464
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0891	0.5317	0.5313
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.0045	0.0036
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0987	0.5911	0.5907
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1228	0.7396	0.7394
Echinococcus granulosus	phosphatidylinositol 4 kinase alpha	0.0107	0.0495	0.0486
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0107	0.0495	0.0486
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0107	0.0495	0.0486
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0554	0.3247	0.3241
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.1652	1	1
Schistosoma mansoni	hypothetical protein	0.0242	0.1325	0.1325
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0107	0.0495	0.0628
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.1652	1	1
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0107	0.0495	0.0486
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0554	0.3247	0.3241
Echinococcus granulosus	sodium channel protein	0.0316	0.1782	0.1775
Loa Loa (eye worm)	hypothetical protein	0.0242	0.1325	0.1317
Brugia malayi	phosphatidylinositol 4-kinase, catalytic, alpha polypeptide	0.0107	0.0495	0.0486
Loa Loa (eye worm)	phosphatidylinositol 3	0.0107	0.0495	0.0486
Trypanosoma brucei	FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative	0.0686	0.406	0.4033
Entamoeba histolytica	phosphatidylinositol 4-kinase, putative	0.0107	0.0495	0.0464
Schistosoma mansoni	voltage-gated potassium channel	0.0031	0.003	0.003
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0892	0.5326	0.5322
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1314	0.7921	0.7919
Echinococcus granulosus	phosphatidylinositol 45 bisphosphate 3 kinase	0.0107	0.0495	0.0486
Loa Loa (eye worm)	hypothetical protein	0.0206	0.1106	0.1098
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0107	0.0495	0.0486
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0107	0.0495	0.0628
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.1652	1	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0891	0.5317	0.5313
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0107	0.0495	0.0464
Trypanosoma brucei	phosphatidylinositol kinase related protein, putative	0.0312	0.1761	0.1724
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0554	0.3247	0.3216
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0312	0.1761	0.1754
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0057	0.0191	0.0182
Echinococcus granulosus	DNA dependent protein kinase catalytic subunit	0.0107	0.0495	0.0486
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0107	0.0495	0.0486
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.0554	0.3247	0.2895
Plasmodium vivax	phosphatidylinositol 4-kinase, putative	0.0107	0.0495	0.5
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0107	0.0495	0.0486
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1228	0.7396	0.7394
Echinococcus multilocularis	serine:threonine protein kinase SMG1	0.0312	0.1761	0.1754
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0107	0.0495	0.0495
Schistosoma mansoni	voltage-gated potassium channel	0.0031	0.003	0.003
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0057	0.0191	0.0182
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0107	0.0495	0.0486
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0107	0.0495	0.5
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.0045	0.0036
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0107	0.0495	0.0486
Echinococcus multilocularis	voltage gated potassium channel	0.0031	0.003	0.0021
Brugia malayi	p70 ribosomal S6 kinase beta	0.0031	0.0033	0.0023
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0312	0.1761	0.1754

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2008240

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1632781