Detailed information for compound 1632790

Basic information

Technical information
  • TDR Targets ID: 1632790
  • Name: [5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3,4-dih ydroxyoxolan-2-yl]methyl dihydrogen phosphate
  • MW: 324.185 | Formula: C8H13N4O8P
  • H donors: 5 H acceptors: 6 LogP: -4.21 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1C(O)C(OC1n1cnc(nc1=O)N)COP(=O)(O)O
  • InChi: 1S/C8H13N4O8P/c9-7-10-2-12(8(15)11-7)6-5(14)4(13)3(20-6)1-19-21(16,17)18/h2-6,13-14H,1H2,(H2,9,11,15)(H2,16,17,18)
  • InChiKey: WODABQYEPQRZOS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
  • [5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3,4-dihydroxy-2-tetrahydrofuranyl]methyl dihydrogen phosphate
  • [5-(4-amino-2-keto-s-triazin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
  • [5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
  • NCI60_005768

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0212 0.1815 0.1801
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0376 0.3291 0.3291
Trichomonas vaginalis conserved hypothetical protein 0.0164 0.1382 0.1367
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0072 0.0557 0.0557
Echinococcus granulosus serine/threonine protein kinase 0.0022 0.0105 0.0105
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0072 0.0557 0.0541
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0072 0.0557 0.0474
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0466 0.4098 0.398
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1122 1 1
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0072 0.0557 0.0557
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0072 0.0557 0.0541
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0072 0.0557 0.0368
Leishmania major phosphatidylinositol 3-kinase, putative 0.0376 0.3291 0.2895
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.002 0.0087 0.0087
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1122 1 1
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0072 0.0557 0.0474
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0072 0.0557 0.0523
Trichomonas vaginalis PIKK family atypical protein kinase 0.014 0.1164 0.1148
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.002 0.0087 0.0087
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0072 0.0557 0.0557
Trypanosoma cruzi Protein kinase B 0.0022 0.0105 0.0018
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0072 0.0557 0.0557
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0197 0.018
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0197 0.018
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0072 0.0557 0.0541
Entamoeba histolytica hypothetical protein 0.0072 0.0557 0.0474
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0197 0.018
Onchocerca volvulus 0.0072 0.0557 0.5
Toxoplasma gondii FATC domain-containing protein 0.0212 0.1815 0.2262
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0072 0.0557 0.0557
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0072 0.0557 1
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0072 0.0557 0.0557
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0197 0.018
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0212 0.1815 0.1815
Trichomonas vaginalis PIKK family atypical protein kinase 0.0834 0.7413 0.7409
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0212 0.1815 0.1743
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0072 0.0557 0.0474
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0072 0.0557 0.0541
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0212 0.1815 0.1815
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0376 0.3291 0.3232
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0072 0.0557 0.0474
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0376 0.3291 0.3156
Loa Loa (eye worm) hypothetical protein 0.0072 0.0557 0.0557
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0072 0.0557 0.0474
Loa Loa (eye worm) AGC/AKT protein kinase 0.0032 0.0197 0.0197
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0072 0.0557 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0606 0.5356 0.5348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0892 0.7935 0.7931
Trichomonas vaginalis PIKK family atypical protein kinase 0.1122 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0605 0.5348 0.534
Giardia lamblia Hypothetical protein 0.0072 0.0557 0.0474
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0072 0.0557 0.0474
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0557 0.5
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0072 0.0557 0.0557
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0072 0.0557 0.0474
Echinococcus granulosus serine protein kinase ATM 0.0212 0.1815 0.1815
Brugia malayi Protein kinase domain containing protein 0.0032 0.0197 0.0197
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0236 0.2033 0.2563
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1122 1 1
Entamoeba histolytica hypothetical protein 0.0072 0.0557 0.0474
Brugia malayi FAT domain containing protein 0.0164 0.1382 0.1382
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1122 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.1122 1 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0072 0.0557 0.0474
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0105 0.0105
Loa Loa (eye worm) phosphatidylinositol 3 0.0072 0.0557 0.0557
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0072 0.0557 0.0557
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0072 0.0557 0.0557
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0261 0.0261
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0072 0.0557 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0834 0.7413 0.7409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0834 0.7413 0.7409
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0261 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0752 0.6677 0.6671
Entamoeba histolytica hypothetical protein 0.0212 0.1815 0.1743
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0197 0.018
Entamoeba histolytica protein kinase, putative 0.003 0.0179 0.0092
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0164 0.1382 0.1382
Trypanosoma cruzi target of rapamycin kinase 3 0.0893 0.7943 0.7925
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0072 0.0557 0.0474
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0072 0.0557 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0834 0.7413 0.7409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0834 0.7413 0.7409
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0072 0.0557 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.067 0.5937 0.593
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0072 0.0557 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0605 0.5348 0.534
Giardia lamblia GTOR 0.1122 1 1
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0072 0.0557 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0072 0.0557 0.0557
Toxoplasma gondii target of rapamycin (TOR), putative 0.0834 0.7413 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0212 0.1815 0.1801
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0072 0.0557 0.0368
Loa Loa (eye worm) phosphatidylinositol 3 0.0376 0.3291 0.3291
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0072 0.0557 0.0541
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0072 0.0557 0.0557
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0072 0.0557 0.0557
Entamoeba histolytica hypothetical protein 0.0072 0.0557 0.0474
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0072 0.0557 0.0557
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0231 0.0231
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.002 0.0085 0.0085
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0072 0.0557 1
Loa Loa (eye worm) hypothetical protein 0.014 0.1164 0.1164
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0072 0.0557 0.0541
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0212 0.1815 0.1815
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0072 0.0557 0.0557
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1122 1 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0893 0.7943 0.7902
Loa Loa (eye worm) hypothetical protein 0.0236 0.2033 0.2033
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.003 0.0179 0.0179
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0105 0.0018
Echinococcus multilocularis nervana 2 0.002 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.2033 0.2019
Echinococcus granulosus Glutaredoxin protein 5 0.002 0.0085 0.0085
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1122 1 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0231 0.0231
Echinococcus granulosus serine threonine protein kinase nrc 0.002 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0072 0.0557 0.0557
Loa Loa (eye worm) phosphatidylinositol kinase 0.0072 0.0557 0.0557
Entamoeba histolytica protein kinase, putative 0.0032 0.0197 0.011
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0072 0.0557 0.0368
Loa Loa (eye worm) phosphatidylinositol 3 0.0072 0.0557 0.0557
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0212 0.1815 0.1743
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1122 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0557 0.0541
Entamoeba histolytica protein kinase, putative 0.0032 0.0197 0.011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0022 0.0105 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0376 0.3291 0.3279
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0376 0.3291 0.3291
Trichomonas vaginalis PIKK family atypical protein kinase 0.067 0.5937 0.593
Trichomonas vaginalis PIKK family atypical protein kinase 0.0376 0.3291 0.3279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0376 0.3291 0.3279
Entamoeba histolytica hypothetical protein 0.0072 0.0557 0.0474
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0212 0.1815 0.1651
Trichomonas vaginalis PIKK family atypical protein kinase 0.1122 1 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0376 0.3291 0.3156
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0072 0.0557 0.0474
Echinococcus granulosus nervana 2 0.002 0.0085 0.0085
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0212 0.1815 0.1743
Trichomonas vaginalis PIKK family atypical protein kinase 0.0892 0.7935 0.7931
Loa Loa (eye worm) hypothetical protein 0.0164 0.1382 0.1382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0376 0.3291 0.3279
Plasmodium vivax hypothetical protein 0.0072 0.0557 1
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.002 0.0085 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0376 0.3291 0.3279
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0072 0.0557 0.0557
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0072 0.0557 0.0541
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0072 0.0557 0.0557
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0212 0.1815 0.1815
Echinococcus multilocularis 0.0072 0.0557 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0892 0.7935 0.7931
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0072 0.0557 0.0474
Echinococcus multilocularis Glutaredoxin protein 5 0.002 0.0085 0.0085
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0072 0.0557 0.0557
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0212 0.1815 0.1815
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0072 0.0557 0.0474
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0072 0.0557 0.0557
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0072 0.0557 0.0523
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0072 0.0557 0.0557
Brugia malayi p70 ribosomal S6 kinase beta 0.003 0.0179 0.0179
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0231 0.0231
Echinococcus multilocularis nervana 2 0.002 0.0085 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0834 0.7413 0.7409
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1122 1 1
Schistosoma mansoni fkbp-rapamycin associated protein 0.0212 0.1815 0.1815
Trichomonas vaginalis PIKK family atypical protein kinase 0.0606 0.5356 0.5348
Onchocerca volvulus 0.0072 0.0557 0.5
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0072 0.0557 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0605 0.5348 0.534
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.021 0.0193
Loa Loa (eye worm) phosphatidylinositol 3 0.0072 0.0557 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.0557 0.0541
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0022 0.0105 0.0018
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0072 0.0557 0.0557
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0197 0.018
Giardia lamblia Phosphatidylinositol 4-kinase 0.0072 0.0557 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0664 0.5878 0.587
Echinococcus multilocularis rac serine:threonine kinase 0.0022 0.0105 0.0105
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0072 0.0557 0.0474
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0072 0.0557 0.0541
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0893 0.7943 0.7822
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0072 0.0557 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.067 0.5937 0.593
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0164 0.1382 0.1382
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0072 0.0557 0.0557
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.014 0.1164 0.1086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0958 0.8524 0.8521
Schistosoma mansoni serine/threonine-protein kinase 0.0022 0.0105 0.0105
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0072 0.0557 0.0474
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0072 0.0557 0.0557
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0072 0.0557 0.0523
Trichomonas vaginalis PIKK family atypical protein kinase 0.1122 1 1
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0557 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0376 0.3291 0.3232
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0072 0.0557 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0072 0.0557 0.5
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0072 0.0557 0.0557
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0072 0.0557 0.0541
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0072 0.0557 0.0523
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.053 0.4679 0.4573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0892 0.7935 0.7931
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0072 0.0557 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0834 0.7413 0.7409
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0072 0.0557 0.0541
Trichomonas vaginalis PIKK family atypical protein kinase 0.0606 0.5356 0.5348
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0072 0.0557 0.0523
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0072 0.0557 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1122 1 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0072 0.0557 0.0541
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0072 0.0557 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0212 0.1815 0.1801
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0072 0.0557 0.0474
Loa Loa (eye worm) hypothetical protein 0.0212 0.1815 0.1815
Trichomonas vaginalis PIKK family atypical protein kinase 0.0892 0.7935 0.7931
Trichomonas vaginalis PIKK family atypical protein kinase 0.0606 0.5356 0.5348
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0072 0.0557 0.0557
Loa Loa (eye worm) phosphatidylinositol 3 0.0072 0.0557 0.0557
Schistosoma mansoni hypothetical protein 0.0164 0.1382 0.1382
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0231 0.0231
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0376 0.3291 0.3291
Entamoeba histolytica protein kinase rad3, putative 0.0212 0.1815 0.1743
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0072 0.0557 0.0474
Loa Loa (eye worm) hypothetical protein 0.0031 0.0188 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0301 0.2614 0.2601
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0072 0.0557 0.0557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0664 0.5878 0.587
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0072 0.0557 0.0557
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.021 0.0193
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0376 0.3291 0.2895
Echinococcus multilocularis Zinc finger, PHD finger 0.0072 0.0557 0.0557
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0197 0.018
Schistosoma mansoni hypothetical protein 0.0072 0.0557 0.0557
Echinococcus granulosus nervana 2 0.002 0.0085 0.0085
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0072 0.0557 1
Loa Loa (eye worm) hypothetical protein 0.0229 0.1963 0.1963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0728 0.6459 0.6453
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0072 0.0557 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.014 0.1164 0.1148
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1122 1 1
Echinococcus multilocularis serine protein kinase ATM 0.0212 0.1815 0.1815
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0376 0.3291 0.3291
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0072 0.0557 0.0541
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1122 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0072 0.0557 0.0557

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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