Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Serotonin 1a (5-HT1a) receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | cytochrome b | 0.0572 | 1 | 1 |
Echinococcus granulosus | cytochrome B | 0.0572 | 1 | 1 |
Schistosoma mansoni | cytochrome b | 0.0572 | 1 | 1 |
Toxoplasma gondii | cytochrome b | 0.0572 | 1 | 0.5 |
Plasmodium vivax | cytochrome b | 0.0572 | 1 | 0.5 |
Plasmodium falciparum | cytochrome b | 0.0572 | 1 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.015 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | cytochrome b subunit of the bc complex | 0.0572 | 1 | 0.5 |
Schistosoma mansoni | cytochrome b | 0.0572 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.015 | 0 | 0.5 |
Toxoplasma gondii | apocytochrome b, putative | 0.0572 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.