Detailed information for compound 1672249

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 283.386 | Formula: C14H21NO3S
  • H donors: 4 H acceptors: 3 LogP: 0.28 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H]1[C@@H](CCSCc2ccccc2)NC[C@H]([C@@H]1O)O
  • InChi: 1S/C14H21NO3S/c16-12-8-15-11(13(17)14(12)18)6-7-19-9-10-4-2-1-3-5-10/h1-5,11-18H,6-9H2/t11-,12-,13+,14+/m1/s1
  • InChiKey: UMFLVFDRLSSIHM-MQYQWHSLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0033 0.0712 0.1287
Loa Loa (eye worm) phosphofructokinase 0.012 0.3396 0.6138
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0802 0.0706
Mycobacterium ulcerans beta-lactamase 0.0036 0.0802 0.1393
Echinococcus multilocularis tar DNA binding protein 0.0064 0.1651 0.2984
Schistosoma mansoni DNA polymerase eta 0.0102 0.2824 0.501
Schistosoma mansoni cpg binding protein 0.0035 0.0765 0.1219
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0707 0.1278
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0334 1 1
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0015 0.0153 0.005
Leishmania major DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Schistosoma mansoni hypothetical protein 0.0033 0.0712 0.1121
Mycobacterium ulcerans hypothetical protein 0.0036 0.0802 0.1393
Brugia malayi 6-phosphofructokinase 0.012 0.3396 0.6064
Echinococcus multilocularis dna polymerase kappa 0.0044 0.1037 0.1874
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.019 0.5533 1
Entamoeba histolytica phosphofructokinase, putative 0.012 0.3396 1
Brugia malayi beta-lactamase family protein 0.0036 0.0802 0.1286
Loa Loa (eye worm) hypothetical protein 0.0036 0.0802 0.1449
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0157 0.4523 0.8138
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0015 0.0153 0.005
Echinococcus multilocularis dna polymerase eta 0.0102 0.2824 0.5104
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.1037 0.2726
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0015 0.0153 0.005
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0802 0.2001
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0015 0.0153 0.0529
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.3396 0.6138
Loa Loa (eye worm) hypothetical protein 0.0014 0.0103 0.0187
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0015 0.0153 0.0276
Schistosoma mansoni cpg binding protein 0.0035 0.0765 0.1219
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.3396 0.3327
Mycobacterium ulcerans hypothetical protein 0.0176 0.5117 1
Schistosoma mansoni cpg binding protein 0.0033 0.0707 0.1112
Echinococcus granulosus GPCR family 2 0.0033 0.0712 0.1287
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0686 0.1645
Schistosoma mansoni hypothetical protein 0.0171 0.4948 0.8922
Mycobacterium ulcerans 6-phosphofructokinase 0.012 0.3396 0.6567
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.1134 0.1041
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.012 0.3396 0.4304
Leishmania major ATP-dependent phosphofructokinase 0.012 0.3396 0.3327
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0044 0.1037 0.1874
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Echinococcus granulosus cpg binding protein 0.0035 0.0765 0.1383
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Brugia malayi beta-lactamase 0.0036 0.0802 0.1286
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0157 0.4523 0.8138
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0686 0.5
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0157 0.4523 0.8173
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.4566 0.4509
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.019 0.5533 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0044 0.1037 0.1719
Loa Loa (eye worm) hypothetical protein 0.0102 0.2824 0.5104
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.3396 0.6138
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Loa Loa (eye worm) pip kinase 1 0.0015 0.0153 0.0276
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0072 0.189 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0802 0.1449
Brugia malayi Pip kinase protein 2 0.019 0.5533 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0072 0.189 0.1806
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0617 0.0519
Echinococcus multilocularis geminin 0.0171 0.4948 0.8942
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0015 0.0153 0.0276
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0686 0.1645
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0802 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0802 0.1449
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0015 0.0153 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.1134 0.1041
Loa Loa (eye worm) beta-lactamase 0.0036 0.0802 0.1449
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0157 0.4523 0.8138
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.1651 0.2851
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.4566 0.4509
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0802 0.2001
Entamoeba histolytica deoxycytidyl transferase, putative 0.0044 0.1037 0.2726
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1651 0.2851
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0686 0.1645
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1651 0.2851
Schistosoma mansoni hypothetical protein 0.0033 0.0712 0.1121
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0686 0.8346
Schistosoma mansoni hypothetical protein 0.0033 0.0712 0.1121
Schistosoma mansoni hypothetical protein 0.0171 0.4948 0.8922
Loa Loa (eye worm) hypothetical protein 0.0105 0.2935 0.5304
Trypanosoma brucei unspecified product 0.0044 0.1037 0.0943
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.019 0.5533 1
Toxoplasma gondii ABC1 family protein 0.0036 0.0802 0.3909
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1651 0.2851
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0015 0.0153 0.005
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.1037 0.1862
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0015 0.0153 0.0091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0802 0.1286
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0157 0.4523 0.8138
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0712 0.1287
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.1037 0.039
Trypanosoma brucei unspecified product 0.003 0.0617 0.0519
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0802 0.1449
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0802 0.2001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.1037 0.039
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0015 0.0153 0.0091
Loa Loa (eye worm) hypothetical protein 0.0072 0.1906 0.3445
Trypanosoma brucei DNA polymerase eta, putative 0.0102 0.2824 0.2749
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0686 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0712 0.1121
Trypanosoma cruzi DNA polymerase eta, putative 0.0102 0.2824 0.2749
Schistosoma mansoni 6-phosphofructokinase 0.012 0.3396 0.6064
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0686 0.3262
Toxoplasma gondii hypothetical protein 0.0054 0.1347 0.696
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0686 0.6244
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Brugia malayi beta-lactamase family protein 0.0036 0.0802 0.1286
Trypanosoma brucei unspecified product 0.003 0.0617 0.0519
Loa Loa (eye worm) hypothetical protein 0.0036 0.0802 0.1449
Schistosoma mansoni 6-phosphofructokinase 0.012 0.3396 0.6064
Mycobacterium ulcerans lipase LipD 0.0036 0.0802 0.1393
Brugia malayi Pip kinase protein 1 0.0015 0.0153 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0617 0.0519
Leishmania major hypothetical protein, conserved 0.0036 0.0802 0.0706
Leishmania major DNA polymerase eta, putative 0.0102 0.2824 0.2749
Loa Loa (eye worm) pip kinase 2 0.019 0.5533 1
Entamoeba histolytica phosphofructokinase, putative 0.012 0.3396 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0157 0.4523 0.8173
Leishmania major DNA polymerase eta, putative 0.0072 0.189 0.1806
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0015 0.0153 0.0276
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0015 0.0153 0.005
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0686 0.3262
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.3396 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.683 1
Echinococcus granulosus geminin 0.0171 0.4948 0.8942
Echinococcus granulosus 6 phosphofructokinase 0.012 0.3396 0.6138
Entamoeba histolytica phosphofructokinase, putative 0.012 0.3396 1
Echinococcus multilocularis cpg binding protein 0.0035 0.0765 0.1383
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0686 0.8346
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0044 0.1037 0.1874
Brugia malayi CXXC zinc finger family protein 0.0033 0.0707 0.1112
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0686 0.1645
Loa Loa (eye worm) RNA binding protein 0.0064 0.1651 0.2984
Mycobacterium tuberculosis Conserved hypothetical protein 0.0176 0.5117 0.7159
Schistosoma mansoni hypothetical protein 0.0072 0.1906 0.332
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0015 0.0153 0.005
Echinococcus granulosus tar DNA binding protein 0.0064 0.1651 0.2984
Echinococcus granulosus dna polymerase kappa 0.0044 0.1037 0.1874
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.2935 0.5215
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Brugia malayi ImpB/MucB/SamB family protein 0.0102 0.2824 0.501
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.1037 0.0943
Onchocerca volvulus 0.0036 0.0802 0.0197
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.1037 0.2726
Brugia malayi RNA binding protein 0.0064 0.1651 0.2851
Loa Loa (eye worm) TAR-binding protein 0.0064 0.1651 0.2984
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.2935 0.5215
Giardia lamblia Hypothetical protein 0.0015 0.0153 0.0529
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0015 0.0153 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Loa Loa (eye worm) hypothetical protein 0.0036 0.0802 0.1449
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0686 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Brugia malayi phosphofructokinase 0.012 0.3396 0.6064
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0686 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0157 0.4523 0.8173
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.1906 0.332
Echinococcus multilocularis 6 phosphofructokinase 0.012 0.3396 0.6138
Trichomonas vaginalis esterase, putative 0.0036 0.0802 0.2001
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0015 0.0153 0.0276
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0802 0.1286
Loa Loa (eye worm) hypothetical protein 0.019 0.5533 1
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0015 0.0153 0.0276
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0015 0.0153 0.0276
Onchocerca volvulus 0.0036 0.0802 0.0197
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0686 0.1645
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.1855 0.3225
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.3396 0.3327
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0802 0.1393
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0712 0.1287
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.1037 0.0943
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0153 0.0707
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0802 0.1393
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.012 0.3396 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.1134 0.1041
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0015 0.0153 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.2935 0.5304
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0015 0.0153 0.005
Echinococcus granulosus dna polymerase eta 0.0102 0.2824 0.5104
Onchocerca volvulus 0.0036 0.0802 0.0197
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0686 0.1645
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0712 0.1287
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.4566 0.4509
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0044 0.1037 0.1874
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0802 0.0706
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0802 0.1449
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.1037 0.1862
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.3396 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.1651 0.2984
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0802 0.2001
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.3396 1
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1651 0.2851
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0802 0.0706
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0712 0.1121
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0015 0.0153 0.0847
Echinococcus multilocularis GPCR, family 2 0.0033 0.0712 0.1287
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0015 0.0153 0.005
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0686 0.3262
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0712 0.1287
Loa Loa (eye worm) hypothetical protein 0.0036 0.0802 0.1449
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0015 0.0153 0.005
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0015 0.0153 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0617 0.0519
Schistosoma mansoni hypothetical protein 0.0033 0.0712 0.1121
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0015 0.0153 0.0707
Brugia malayi TAR-binding protein 0.0064 0.1651 0.2851
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0686 0.1645
Loa Loa (eye worm) FYVE zinc finger family protein 0.0015 0.0153 0.0276
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0015 0.0153 0.0091
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.019 0.5533 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.1134 0.1041
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0157 0.4523 0.8173
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.1623 0.8502
Loa Loa (eye worm) hypothetical protein 0.0036 0.0802 0.1449
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0044 0.1037 0.1719
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.1451 0.1362
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.1037 0.1719
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0015 0.0153 0.0276
Giardia lamblia DINP protein human, muc B family 0.0044 0.1037 1
Brugia malayi 6-phosphofructokinase 0.012 0.3396 0.6064
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0015 0.0153 0.005
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0802 0.2001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0157 0.4523 0.8173
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1651 0.2851
Onchocerca volvulus 0.019 0.5533 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0334 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.3396 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0015 0.0153 0.005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0712 0.1287
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0802 0.1286
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0015 0.0153 0.0091
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.1037 0.0943
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.1037 0.0943
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0015 0.0153 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1037 0.0943
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0015 0.0153 0.0276
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.012 0.3396 1
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0686 0.1645
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0015 0.0153 0.005

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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