Detailed information for compound 1683012

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 505.388 | Formula: C20H21BrN6O3S
  • H donors: 1 H acceptors: 4 LogP: 3.7 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=CN1CCC(CC1)CCn1c(Sc2cc3OCOc3cc2Br)nc2c1ncnc2N
  • InChi: 1S/C20H21BrN6O3S/c21-13-7-14-15(30-11-29-14)8-16(13)31-20-25-17-18(22)23-9-24-19(17)27(20)6-3-12-1-4-26(10-28)5-2-12/h7-10,12H,1-6,11H2,(H2,22,23,24)
  • InChiKey: QKASCVDKULMPHI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B member 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma brucei Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock 90 kDa protein homolog Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax heat shock protein 86, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium hominis heat shock protein 83 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Theileria parva heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein HSP90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii putative heat shock protein 81-2 Get druggable targets OG5_126623 All targets in OG5_126623
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-alpha, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Endoplasmin precursor Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90-like protein, related Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein heat shock protein 90 alpha Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09487 heat shock protein 90kDa beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis hsp90 protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense heat shock protein 83,heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans hypothetical protein Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Treponema pallidum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K04079 molecular chaperone HtpG, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90, related Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Grp94/Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum heat shock protein 90, putative heat shock protein 90kDa alpha (cytosolic), class B member 1 724 aa 725 aa 35.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0031 0.0929 0.5
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1799 0.1698
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.1456 1
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0929 0.503
Echinococcus multilocularis heat shock protein 90 0.0031 0.0929 0.0816
Plasmodium vivax endoplasmin, putative 0.0039 0.1456 0.5
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Echinococcus multilocularis geminin 0.0169 1 1
Schistosoma mansoni bromodomain containing protein 0.0062 0.2924 0.2836
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Plasmodium falciparum heat shock protein 90 0.0039 0.1456 1
Loa Loa (eye worm) PHD-finger family protein 0.002 0.019 0.0559
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0929 0.4732
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.1171 0.1061
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Schistosoma mansoni endoplasmin 0.0039 0.1456 0.135
Brugia malayi heat shock protein 90 0.0039 0.1456 0.3089
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.1456 1
Echinococcus granulosus heat shock protein 0.0039 0.1456 0.135
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1799 0.1698
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.1456 1
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1799 0.1698
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Treponema pallidum heat shock protein 90 0.0031 0.0929 0.5
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.1799 0.4159
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.1456 1
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Schistosoma mansoni heat shock protein 0.0039 0.1456 0.135
Schistosoma mansoni hypothetical protein 0.0169 1 1
Echinococcus multilocularis heat shock protein 90 0.0039 0.1456 0.135
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1799 0.1698
Loa Loa (eye worm) hypothetical protein 0.004 0.1479 0.4348
Trypanosoma brucei Heat shock protein 83, putative 0.0039 0.1456 0.5
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Trypanosoma cruzi Heat shock protein 83, putative 0.0039 0.1456 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.2694 0.2604
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.1456 0.5
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0929 0.4732
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0313 0.0193
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1799 0.1698
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0313 0.0193
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Schistosoma mansoni endoplasmin 0.0039 0.1456 0.135
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0031 0.0929 0.5
Loa Loa (eye worm) hypothetical protein 0.0037 0.1327 0.3902
Toxoplasma gondii heat shock protein 90, putative 0.0039 0.1456 0.5
Trichomonas vaginalis heat shock protein, putative 0.0039 0.1456 1
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0031 0.0929 0.5
Mycobacterium ulcerans heat shock protein 90 0.0031 0.0929 0.5
Loa Loa (eye worm) hypothetical protein 0.0041 0.1601 0.4709
Loa Loa (eye worm) endoplasmin 0.0039 0.1456 0.4282
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Trypanosoma cruzi heat shock protein 90, putative 0.0031 0.0929 0.503
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.1799 0.5292
Echinococcus multilocularis endoplasmin 0.0031 0.0929 0.0816
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.1456 0.5
Schistosoma mansoni hypothetical protein 0.002 0.019 0.0069
Plasmodium vivax heat shock protein 86, putative 0.0039 0.1456 0.5
Brugia malayi Endoplasmin precursor 0.0039 0.1456 0.3089
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.1171 0.1061
Toxoplasma gondii heat shock protein HSP90 0.0039 0.1456 0.5
Echinococcus multilocularis heat shock protein 0.0039 0.1456 0.135
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.1456 0.5
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.2694 0.2604
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0929 0.4732
Echinococcus granulosus endoplasmin 0.0031 0.0929 0.0816
Echinococcus granulosus heat shock protein 90 0.0031 0.0929 0.0816
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0031 0.0929 0.0816
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0313 0.0193
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.1456 0.5
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Brugia malayi Bromodomain containing protein 0.0037 0.1322 0.2673
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1799 0.1698
Schistosoma mansoni hypothetical protein 0.0169 1 1
Trypanosoma brucei heat shock protein, putative 0.0039 0.1456 0.5
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.3401 1
Loa Loa (eye worm) heat shock protein 90 0.0039 0.1456 0.4282
Schistosoma mansoni heat shock protein 0.0039 0.1456 0.135
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.1456 1
Brugia malayi Bromodomain containing protein 0.0073 0.3675 1
Echinococcus granulosus heat shock protein 90 0.0039 0.1456 0.135
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1799 0.1698
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Leishmania major heat shock protein 83-1 0.0039 0.1456 1
Leishmania major heat shock protein 83-1 0.0039 0.1456 1

Activities

Activity type Activity value Assay description Source Reference
F (ADMET) > 50 % Oral bioavailability in Swiss nude mouse at 10 mg/kg administered using captisol and phosphate buffer system formulation by LC-ESI-MS/MS method ChEMBL. 22913511
IC50 (binding) = 0.07 uM Inhibition of human HSP90 in HCT116 cells expressing Her2 gene assessed as degradation of Her2 after 4 hrs by luciferase reporter gene assay ChEMBL. 22913511
IC50 (binding) = 0.15 uM Inhibition of human HSP90 using BODIPY labelled geldanamycin as substrate by fluorescence polarization assay ChEMBL. 22913511
IC50 (functional) = 0.43 uM Cytotoxicity against human HCT116 cells assessed as inhibition of tumor growth incubated for 72 hrs by luminometry ChEMBL. 22913511

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 22913511

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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