Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Candida albicans | secretory aspartyl proteinase SAP2p | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | plexin a4 | 0.0021 | 0.9857 | 0.9857 |
Echinococcus multilocularis | plexin a4 | 0.0021 | 0.9857 | 0.9857 |
Plasmodium falciparum | plasmepsin X | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.6974 | 0.6974 |
Brugia malayi | plexin A | 0.0021 | 0.9857 | 0.9857 |
Brugia malayi | Plexin repeat family protein | 0.0018 | 0.6974 | 0.6974 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Toxoplasma gondii | aspartyl protease | 0.0021 | 1 | 0.5 |
Onchocerca volvulus | 0.0021 | 1 | 1 | |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0021 | 1 | 1 |
Schistosoma mansoni | plexin | 0.0018 | 0.6974 | 0.6974 |
Brugia malayi | hypothetical protein | 0.0021 | 1 | 1 |
Plasmodium falciparum | plasmepsin I | 0.0021 | 1 | 0.5 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0021 | 1 | 0.5 |
Plasmodium falciparum | plasmepsin III | 0.0021 | 1 | 0.5 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0021 | 1 | 0.5 |
Brugia malayi | Pepsin A precursor | 0.0021 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0393 | 0.0393 |
Plasmodium vivax | plasmepsin V, putative | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Plasmodium vivax | aspartyl protease, putative | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0021 | 1 | 1 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0021 | 1 | 0.5 |
Plasmodium falciparum | plasmepsin VII | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0021 | 1 | 1 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0021 | 1 | 0.5 |
Onchocerca volvulus | 0.0021 | 1 | 1 | |
Plasmodium vivax | plasmepsin IV, putative | 0.0021 | 1 | 0.5 |
Plasmodium falciparum | plasmepsin IX | 0.0021 | 1 | 0.5 |
Plasmodium vivax | aspartyl protease, putative | 0.0021 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 1 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0021 | 1 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0021 | 1 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0021 | 1 | 1 |
Plasmodium vivax | aspartyl protease, putative | 0.0021 | 1 | 0.5 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0021 | 1 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0393 | 0.0393 |
Plasmodium falciparum | plasmepsin IV | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0021 | 1 | 1 |
Plasmodium falciparum | plasmepsin V | 0.0021 | 1 | 0.5 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0021 | 1 | 0.5 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0021 | 1 | 1 |
Plasmodium falciparum | plasmepsin II | 0.0021 | 1 | 0.5 |
Onchocerca volvulus | 0.0018 | 0.6974 | 0.6974 | |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0021 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 1 | 1 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0021 | 1 | 1 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0021 | 1 | 1 |
Schistosoma mansoni | plexin | 0.001 | 0.0393 | 0.0393 |
Plasmodium falciparum | plasmepsin VI | 0.0021 | 1 | 0.5 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0021 | 1 | 0.5 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0021 | 1 | 0.5 |
Loa Loa (eye worm) | plexin A | 0.0021 | 0.9857 | 0.9857 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 10 uM | Inhibition of candida albicans SAP2 using 0.05% BSA as substrate by spectrophotometric analysis | ChEMBL. | 23123016 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.