Detailed information for compound 1690490

Basic information

Technical information
  • TDR Targets ID: 1690490
  • Name: 3-hydroxy-N-(4-hydroxyphenyl)naphthalene-2-ca rboxamide
  • MW: 279.29 | Formula: C17H13NO3
  • H donors: 3 H acceptors: 3 LogP: 3.85 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)NC(=O)c1cc2ccccc2cc1O
  • InChi: 1S/C17H13NO3/c19-14-7-5-13(6-8-14)18-17(21)15-9-11-3-1-2-4-12(11)10-16(15)20/h1-10,19-20H,(H,18,21)
  • InChiKey: VSGDHUXKHRQXMJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-hydroxy-N-(4-hydroxyphenyl)-2-naphthalenecarboxamide
  • 3-hydroxy-N-(4-hydroxyphenyl)-2-naphthamide
  • Oprea1_731890
  • Oprea1_054240
  • T0502-7558
  • ZINC03190822

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei heat shock protein 90, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) BEN-1 protein 0.0214 0.0275 0.0275
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0015 0.0446
Trypanosoma cruzi beta tubulin, putative 0.0214 0.0275 1
Echinococcus multilocularis beta tubulin 0.0214 0.0275 0.0496
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Onchocerca volvulus 0.024 0.0315 0.0513
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0554 0.0796 0.2813
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0049 0.0087
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0049 0.1524
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.024 0.0315 0.0715
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.024 0.0315 0.0315
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Plasmodium vivax endoplasmin, putative 0.0146 0.0171 0.5906
Trichomonas vaginalis tubulin, putative 0.0214 0.0275 0.7996
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Echinococcus multilocularis allatostatin A receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) acetyltransferase 0.0167 0.0203 0.0203
Echinococcus granulosus alpha 1A adrenergic receptor 0.024 0.0315 0.0568
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0132 0.015 0.5
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0462 0.0656 0.0656
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Brugia malayi Melatonin receptor type 1A 0.024 0.0315 0.0315
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0224 0.0291 0.0525
Echinococcus granulosus heat shock protein 0.0146 0.0171 0.0309
Entamoeba histolytica heat shock protein 90, putative 0.0146 0.0171 0.6238
Echinococcus multilocularis g-protein coupled receptor 0.024 0.0315 0.0568
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Schistosoma mansoni heat shock protein 0.0146 0.0171 0.0389
Echinococcus multilocularis g protein coupled receptor 0.024 0.0315 0.0568
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0015 0.0028
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0224 0.0291 0.0525
Onchocerca volvulus 0.024 0.0315 0.0513
Onchocerca volvulus 0.024 0.0315 0.0513
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi ORL1-like opioid receptor 0.024 0.0315 0.0315
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0103 0.0105 0.0105
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0167 0.0203 0.046
Giardia lamblia Beta tubulin 0.0214 0.0275 1
Echinococcus granulosus dna polymerase kappa 0.0044 0.0015 0.0028
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.024 0.0315 0.0568
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trichomonas vaginalis tubulin beta chain, putative 0.0214 0.0275 0.7996
Loa Loa (eye worm) tubulin beta-4 chain 0.0214 0.0275 0.0275
Trypanosoma cruzi heat shock protein 85, putative 0.0146 0.0171 0.6238
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus G protein coupled receptor 139 0.024 0.0315 0.0568
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0527 0.0756 0.1363
Schistosoma mansoni myosin xvIII 0.024 0.0315 0.0715
Brugia malayi Serotonin/octopamine receptor family protein 7 0.024 0.0315 0.0315
Echinococcus multilocularis neuropeptides capa receptor 0.024 0.0315 0.0568
Toxoplasma gondii heat shock protein HSP90 0.0146 0.0171 0.0283
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.2809 0.4254 0.7673
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Trypanosoma cruzi heat shock protein 85, putative 0.0146 0.0171 0.6238
Brugia malayi Calcitonin receptor-like protein seb-1 0.4267 0.6489 0.6489
Echinococcus multilocularis heat shock protein 0.0146 0.0171 0.0309
Echinococcus granulosus beta tubulin 0.0214 0.0275 0.0496
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Schistosoma mansoni biogenic amine receptor 0.024 0.0315 0.0715
Echinococcus multilocularis neuropeptide receptor 0.126 0.1879 0.3389
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Echinococcus multilocularis integrin beta 2 0.0501 0.0715 0.1289
Echinococcus granulosus beta tubulin 0.0214 0.0275 0.0496
Giardia lamblia Heat shock protein HSP 90-alpha 0.0146 0.0171 0.6238
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0006 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni growth hormone secretagogue receptor 0.024 0.0315 0.0715
Echinococcus multilocularis dual specificity mitogen activated protein 0.0072 0.0057 0.0103
Schistosoma mansoni endoplasmin 0.0146 0.0171 0.0389
Schistosoma mansoni opsin-like receptor 0.024 0.0315 0.0715
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Trypanosoma cruzi heat shock protein 90, putative 0.0132 0.015 0.5467
Echinococcus multilocularis neuropeptide FF receptor 2 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus heat shock protein 90 0.0132 0.015 0.0271
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus dual specificity mitogen activated protein 0.0072 0.0057 0.0103
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0072 0.0057 0.2088
Brugia malayi follicle stimulating hormone receptor 0.0462 0.0656 0.0656
Brugia malayi Dopamine receptor protein 1 0.024 0.0315 0.0315
Echinococcus granulosus fmrfamide receptor 0.024 0.0315 0.0568
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Echinococcus granulosus neuropeptide FF receptor 2 0.024 0.0315 0.0568
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus granulosus 7tm_1 domain containing protein 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Toxoplasma gondii heat shock protein 90, putative 0.0146 0.0171 0.0283
Echinococcus multilocularis tubulin subunit beta 0.0214 0.0275 0.0496
Entamoeba histolytica heat shock protein 90, putative 0.0146 0.0171 0.6238
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Giardia lamblia Kinase, STE STE20 0.0072 0.0057 0.2088
Trichomonas vaginalis heat shock protein, putative 0.0132 0.015 0.4371
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Trichomonas vaginalis STE family protein kinase 0.0072 0.0057 0.1669
Giardia lamblia Heat shock protein HSP 90-alpha 0.0132 0.015 0.5467
Entamoeba histolytica tubulin family protein 0.0214 0.0275 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0221 0.644
Loa Loa (eye worm) tubulin beta-2A chain 0.0214 0.0275 0.0275
Echinococcus multilocularis g protein coupled receptor 0.024 0.0315 0.0568
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.024 0.0315 0.0715
Toxoplasma gondii beta tubulin 0.0214 0.0275 0.0454
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trichomonas vaginalis heat shock protein, putative 0.0132 0.015 0.4371
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Echinococcus granulosus tubulin subunit beta 0.0214 0.0275 0.0496
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.1361 0.2034 0.2034
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.0224 0.0291 0.0661
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.024 0.0315 0.0315
Onchocerca volvulus Neuropeptide F receptor homolog 0.024 0.0315 0.0513
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.024 0.0315 0.0715
Onchocerca volvulus 0.024 0.0315 0.0513
Schistosoma mansoni hypothetical protein 0.2906 0.4403 1
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Onchocerca volvulus 0.024 0.0315 0.0513
Plasmodium vivax tubulin beta chain, putative 0.0214 0.0275 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi RE15519p 0.024 0.0315 0.0315
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) tubulin beta-1 chain 0.0214 0.0275 0.0275
Echinococcus multilocularis g protein coupled receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Schistosoma mansoni histamine h1 receptor 0.024 0.0315 0.0715
Echinococcus granulosus biogenic amine 5HT receptor 0.024 0.0315 0.0568
Toxoplasma gondii beta-1 tubulin, putative 0.0214 0.0275 0.0454
Schistosoma mansoni opsin-like receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.2906 0.4403 0.4403
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Plasmodium falciparum heat shock protein 90 0.0146 0.0171 0.6238
Echinococcus granulosus histone acetyltransferase KAT2B 0.0162 0.0195 0.0352
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.024 0.0315 0.0568
Echinococcus multilocularis G protein coupled receptor 139 0.126 0.1879 0.3389
Plasmodium falciparum tubulin beta chain 0.0214 0.0275 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) BEN-1 protein 0.0214 0.0275 0.0275
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.365 0.5544 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Brugia malayi putative neuropeptide receptor NPR1 0.024 0.0315 0.0315
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0072 0.0057 0.2088
Plasmodium vivax heat shock protein 86, putative 0.0146 0.0171 0.5906
Giardia lamblia Beta tubulin 0.0214 0.0275 1
Schistosoma mansoni integrin beta subunit 0.0398 0.0557 0.1266
Schistosoma mansoni biogenic amine receptor 0.024 0.0315 0.0715
Echinococcus multilocularis adenylate cyclase type IX 0.0194 0.0245 0.0442
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptide Y receptor 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Brugia malayi Serotonin receptor 0.024 0.0315 0.0315
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus multilocularis fmrfamide receptor 0.024 0.0315 0.0568
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0022 0.0037
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Brugia malayi larval opioid receptor 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptide receptor A26 0.024 0.0315 0.0568
Brugia malayi putative neuropeptide receptor 0.024 0.0315 0.0315
Loa Loa (eye worm) neuropeptide F receptor 0.024 0.0315 0.0315
Brugia malayi heat shock protein 90 0.0146 0.0171 0.0171
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.024 0.0315 0.0715
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Plasmodium falciparum endoplasmin, putative 0.0042 0.0011 0.0398
Onchocerca volvulus 0.024 0.0315 0.0513
Brugia malayi G protein-coupled receptor 0.024 0.0315 0.0315
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0016 0.0582
Loa Loa (eye worm) hypothetical protein 0.0554 0.0796 0.0796
Echinococcus multilocularis endoplasmin 0.0132 0.015 0.0271
Brugia malayi Serotonin receptor 0.024 0.0315 0.0315
Loa Loa (eye worm) beta-tubulin 0.0214 0.0275 0.0275
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.024 0.0315 0.0715
Schistosoma mansoni neuropeptide receptor 0.024 0.0315 0.0715
Echinococcus granulosus g protein coupled receptor 0.024 0.0315 0.0568
Trichomonas vaginalis heat shock protein, putative 0.0132 0.015 0.4371
Brugia malayi hypothetical protein 0.0103 0.0105 0.0105
Onchocerca volvulus 0.024 0.0315 0.0513
Brugia malayi neuropeptide F receptor 0.024 0.0315 0.0315
Echinococcus multilocularis biogenic amine (5HT) receptor 0.024 0.0315 0.0568
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Echinococcus multilocularis G-protein coupled receptor, putative 0.024 0.0315 0.0568
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Trypanosoma cruzi heat shock protein 90, putative 0.0118 0.0129 0.4687
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0221 0.644
Onchocerca volvulus 0.024 0.0315 0.0513
Trypanosoma brucei Heat shock protein 83, putative 0.0146 0.0171 0.6238
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Loa Loa (eye worm) pigment dispersing factor receptor c 0.4267 0.6489 0.6489
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0049 0.1765
Loa Loa (eye worm) hypothetical protein 0.6556 1 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis neuropeptide Y receptor 0.024 0.0315 0.0568
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Trypanosoma cruzi heat shock protein 85, putative 0.0132 0.015 0.5467
Echinococcus granulosus neuropeptide receptor 0.126 0.1879 0.3389
Echinococcus multilocularis serotonin receptor 0.024 0.0315 0.0568
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Echinococcus granulosus integrin beta 2 0.0501 0.0715 0.1289
Echinococcus granulosus g protein coupled receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi Caveolin-1 0.053 0.0759 0.0759
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.024 0.0315 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0049 0.011
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Brugia malayi Dopamine receptor 0.024 0.0315 0.0315
Brugia malayi G-protein coupled receptor 0.024 0.0315 0.0315
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0004 0.0159
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus neuropeptides capa receptor 0.024 0.0315 0.0568
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0132 0.015 0.5
Brugia malayi Endoplasmin precursor 0.0146 0.0171 0.0171
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0049 0.0087
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.1361 0.2034 0.3668
Echinococcus multilocularis adenylate cyclase 9 0.0554 0.0796 0.1436
Echinococcus multilocularis heat shock protein 90 0.0132 0.015 0.0271
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Echinococcus granulosus hypothetical protein 0.024 0.0315 0.0568
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Giardia lamblia Beta tubulin 0.0214 0.0275 1
Brugia malayi G-protein coupled receptor 0.024 0.0315 0.0315
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) neuropeptide F receptor 0.024 0.0315 0.0315
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.024 0.0315 0.0513
Echinococcus granulosus g protein coupled receptor 0.024 0.0315 0.0568
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0016 0.0582
Echinococcus granulosus tubulin beta 1 chain 0.0214 0.0275 0.0496
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.3979 0.6049 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0015 0.0558
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.024 0.0315 0.0715
Schistosoma mansoni hypothetical protein 0.0224 0.0291 0.0661
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Loa Loa (eye worm) G-protein coupled receptor 0.024 0.0315 0.0315
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trichomonas vaginalis STE family protein kinase 0.0072 0.0057 0.1669
Echinococcus granulosus tachykinin peptides receptor 99D 0.0527 0.0756 0.1363
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Echinococcus granulosus thyrotropin releasing hormone receptor 0.024 0.0315 0.0568
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi Dopamine receptor protein 2 0.024 0.0315 0.0315
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0132 0.015 0.4718
Schistosoma mansoni biogenic amine (5HT) receptor 0.024 0.0315 0.0715
Trypanosoma brucei unspecified product 0.0037 0.0004 0.0159
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) hypothetical protein 0.0103 0.0105 0.0105
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.024 0.0315 0.0315
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.1511 0.2263 0.2263
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0214 0.0275 0.0496
Echinococcus granulosus allatostatin A receptor 0.024 0.0315 0.0568
Brugia malayi sulfakinin receptor protein 0.024 0.0315 0.0315
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0132 0.015 0.0271
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Brugia malayi acetyltransferase, GNAT family protein 0.0167 0.0203 0.0203
Echinococcus multilocularis fmrfamide receptor 0.024 0.0315 0.0568
Echinococcus granulosus serotonin receptor 0.024 0.0315 0.0568
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.1361 0.2034 0.2034
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Trichomonas vaginalis tubulin alpha chain, putative 0.0214 0.0275 0.7996
Echinococcus multilocularis heat shock protein 90 0.0146 0.0171 0.0309
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus granulosus tubulin beta 4A class IVa 0.0214 0.0275 0.0496
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Schistosoma mansoni peptide (allatostatin)-like receptor 0.024 0.0315 0.0715
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.365 0.5544 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0224 0.0291 0.0661
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis orexin receptor type 2 0.024 0.0315 0.0568
Schistosoma mansoni hypothetical protein 0.0224 0.0291 0.0661
Echinococcus granulosus heat shock protein 90 0.0146 0.0171 0.0309
Loa Loa (eye worm) latrophilin receptor protein 2 0.1361 0.2034 0.2034
Echinococcus granulosus neuropeptide Y receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus adenylate cyclase 9 0.0554 0.0796 0.1436
Brugia malayi GnHR receptor homolog 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptide receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) G-protein coupled receptor 0.024 0.0315 0.0315
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.1361 0.2034 0.3668
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Echinococcus granulosus GPCR family 2 0.1361 0.2034 0.3668
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Brugia malayi AKH receptor 0.024 0.0315 0.0315
Trypanosoma cruzi Heat shock protein 83, putative 0.0146 0.0171 0.6238
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0224 0.0291 0.0291
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0132 0.015 0.5
Brugia malayi G protein-coupled receptor F59B2.13 0.024 0.0315 0.0315
Onchocerca volvulus 0.0554 0.0796 0.2813
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Onchocerca volvulus 0.024 0.0315 0.0513
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Onchocerca volvulus 0.024 0.0315 0.0513
Loa Loa (eye worm) TYRA-2 protein 0.024 0.0315 0.0315
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0242 0.0318 0.0574
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) hypothetical protein 0.0224 0.0291 0.0291
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0072 0.0057 0.0057
Loa Loa (eye worm) apoptosis regulator protein 0.0224 0.0291 0.0291
Schistosoma mansoni biogenic amine (dopamine) receptor 0.024 0.0315 0.0715
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus multilocularis neuropeptides capa receptor 0.024 0.0315 0.0568
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.024 0.0315 0.0568
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Schistosoma mansoni neuropeptide receptor 0.126 0.1879 0.4267
Echinococcus granulosus tm gpcr rhodopsin 0.024 0.0315 0.0568
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Echinococcus multilocularis serotonin receptor 0.024 0.0315 0.0568
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Brugia malayi Integrin beta pat-3 precursor 0.058 0.0837 0.0837
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) integrin beta-2 0.058 0.0837 0.0837
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus granulosus peptide allatostatin:somatostatin 0.024 0.0315 0.0568
Schistosoma mansoni endoplasmin 0.0146 0.0171 0.0389
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Schistosoma mansoni opsin-like receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.024 0.0315 0.0315
Treponema pallidum heat shock protein 90 0.0132 0.015 0.5
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Entamoeba histolytica tubulin family protein 0.0214 0.0275 1
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0072 0.0057 0.1802
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Brugia malayi Tubulin beta-1 chain 0.0214 0.0275 0.0275
Trichomonas vaginalis tubulin gamma chain, putative 0.0214 0.0275 0.7996
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.024 0.0315 0.0568
Echinococcus granulosus neuropeptide s receptor 0.024 0.0315 0.0568
Schistosoma mansoni neuropeptide receptor 0.024 0.0315 0.0715
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Schistosoma mansoni neuropeptide F-like receptor 0.024 0.0315 0.0715
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0015 0.0446
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.2809 0.4254 0.7673
Trichomonas vaginalis STE family protein kinase 0.0072 0.0057 0.1669
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0022 0.0037
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Schistosoma mansoni neuropeptide f receptor 76f 0.024 0.0315 0.0715
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0022 0.0647
Echinococcus multilocularis dro:myosuppressin receptor 0.024 0.0315 0.0568
Echinococcus multilocularis neuropeptide Y receptor 0.024 0.0315 0.0568
Echinococcus multilocularis sodium channel protein 0.0242 0.0318 0.0574
Echinococcus granulosus sex peptide receptor 0.024 0.0315 0.0568
Echinococcus multilocularis beta tubulin 0.0214 0.0275 0.0496
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus dro:myosuppressin receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) heat shock protein 90 0.0146 0.0171 0.0171
Schistosoma mansoni heat shock protein 0.0146 0.0171 0.0389
Trypanosoma brucei heat shock protein 90, putative 0.0146 0.0171 0.6238
Toxoplasma gondii beta-tubulin, putative 0.0214 0.0275 0.0454
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Schistosoma mansoni neuropeptide F-like receptor 0.024 0.0315 0.0715
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi Latrophilin receptor protein 2 0.1361 0.2034 0.2034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.024 0.0315 0.0568
Schistosoma mansoni adenoreceptor 0.024 0.0315 0.0715
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Echinococcus multilocularis neuropeptide receptor 0.024 0.0315 0.0568
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0011 0.0318
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.024 0.0315 0.0715
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni biogenic amine (dopamine) receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis sex peptide receptor 0.024 0.0315 0.0568
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0049 0.1765
Loa Loa (eye worm) endoplasmin 0.0146 0.0171 0.0171
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Schistosoma mansoni serine-type protease inhibitor 0.0457 0.0648 0.1471
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0016 0.0582
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptides capa receptor 0.024 0.0315 0.0568
Echinococcus granulosus tm gpcr rhodopsin 0.024 0.0315 0.0568
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.1534 0.2299 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0167 0.0203 0.0365
Brugia malayi latrophilin 2 splice variant baaae 0.2906 0.4403 0.4403
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0022 0.004
Schistosoma mansoni biogenic amine (5HT) receptor 0.024 0.0315 0.0715
Brugia malayi Adenylyl cyclase protein 0.0554 0.0796 0.0796
Echinococcus granulosus biogenic amine 5HT receptor 0.024 0.0315 0.0568
Echinococcus multilocularis alpha 1A adrenergic receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0072 0.0057 0.0057
Onchocerca volvulus 0.024 0.0315 0.0513
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0242 0.0318 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.024 0.0315 0.0315
Echinococcus granulosus g-protein coupled receptor 0.024 0.0315 0.0568
Trypanosoma cruzi heat shock protein 90, putative 0.0146 0.0171 0.6238
Schistosoma mansoni serine-type protease inhibitor 0.0457 0.0648 0.1471
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.024 0.0315 0.0568
Onchocerca volvulus 0.024 0.0315 0.0513
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0022 0.0647
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus sodium channel protein 0.0242 0.0318 0.0574
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Echinococcus multilocularis GPCR, family 2 0.1361 0.2034 0.3668
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0049 0.1765
Schistosoma mansoni protein kinase 0.0072 0.0057 0.013
Trichomonas vaginalis heat shock protein, putative 0.0146 0.0171 0.4987
Giardia lamblia Grp94/Hsp90 0.0132 0.015 0.5467
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Echinococcus multilocularis neuropeptide receptor A26 0.024 0.0315 0.0568
Brugia malayi neuropeptide F receptor 0.024 0.0315 0.0315
Brugia malayi gonadotropin-releasing hormone receptor 2 0.024 0.0315 0.0315
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.024 0.0315 0.0568
Echinococcus multilocularis neuropeptide s receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus endoplasmin 0.0132 0.015 0.0271
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Echinococcus granulosus tm gpcr rhodopsin 0.024 0.0315 0.0568
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.024 0.0315 0.0315
Trichomonas vaginalis tubulin epsilon chain, putative 0.0214 0.0275 0.7996
Trypanosoma cruzi heat shock protein 85, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.0344 0.0344
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Schistosoma mansoni apoptosis regulator bax 0.0224 0.0291 0.0661
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Mycobacterium ulcerans heat shock protein 90 0.0132 0.015 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis somatostatin receptor 0.024 0.0315 0.0568
Brugia malayi Tachykinin-like peptides receptor 99D 0.024 0.0315 0.0315
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.024 0.0315 0.0568
Echinococcus granulosus orexin receptor type 2 0.024 0.0315 0.0568
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Onchocerca volvulus 0.053 0.076 0.2641
Trichomonas vaginalis endoplasmin, putative 0.0042 0.0011 0.0318
Schistosoma mansoni alpha-1 adrenergic receptor 0.024 0.0315 0.0715
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Loa Loa (eye worm) adenylyl cyclase 3 0.0724 0.1058 0.1058
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni neuropeptide receptor 0.024 0.0315 0.0715
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trichomonas vaginalis tubulin epsilon chain, putative 0.0214 0.0275 0.7996
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Schistosoma mansoni biogenic amine (dopamine) receptor 0.024 0.0315 0.0715
Echinococcus granulosus somatostatin receptor 0.024 0.0315 0.0568
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Loa Loa (eye worm) melatonin receptor type 1A 0.024 0.0315 0.0315
Schistosoma mansoni biogenic amine receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) tubulin beta chain 0.0214 0.0275 0.0275
Echinococcus granulosus 7TM GPCR rhodopsin 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0049 0.1765
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0015 0.0558
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.053 0.0759 0.0759
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus adenylate cyclase type IX 0.0194 0.0245 0.0442
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Onchocerca volvulus 0.024 0.0315 0.0513
Brugia malayi beta-tubulin, identical 0.0214 0.0275 0.0275
Brugia malayi Kelch motif family protein 0.0103 0.0105 0.0105
Echinococcus multilocularis tubulin beta 1 chain 0.0214 0.0275 0.0496

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) > 100 uM Growth inhibition of human MDA-MB-231 cells after 72 hrs by MTT assay ChEMBL. 23102993

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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