Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0463 | 0.578 | 0.578 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0342 | 0.0968 |
Echinococcus granulosus | phenylalanyl tRNA synthetase | 0.0048 | 0.0366 | 0.0633 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.0367 | 0.1883 |
Loa Loa (eye worm) | phenylalanyl-tRNA synthetase | 0.0048 | 0.0366 | 0.1876 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0109 | 0.1163 | 0.2012 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0524 | 0.0906 |
Plasmodium vivax | phenylalanine--tRNA ligase alpha subunit, putative | 0.0165 | 0.1889 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0342 | 0.1747 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0367 | 0.1634 |
Brugia malayi | 6-phosphofructokinase | 0.0109 | 0.1163 | 0.6009 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0453 | 0.0453 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0524 | 0.0524 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0342 | 0.0342 |
Entamoeba histolytica | phenylalanyl-tRNA synthetase alpha subunit, putative | 0.0165 | 0.1889 | 1 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0367 | 0.1634 |
Brugia malayi | phenylalanyl (f) trna synthetase protein 1 | 0.0165 | 0.1889 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0109 | 0.1163 | 0.5878 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.057 | 0.1616 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0039 | 0.0067 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0039 | 0.011 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.1163 | 0.5878 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0342 | 0.0342 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0367 | 0.104 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.0048 | 0.0366 | 0.135 |
Mycobacterium tuberculosis | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.0785 | 0.9974 | 1 |
Brugia malayi | phosphofructokinase | 0.0109 | 0.1163 | 0.6009 |
Treponema pallidum | phenylalanyl-tRNA synthetase subunit alpha | 0.0165 | 0.1889 | 1 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0165 | 0.1889 | 0.5354 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0342 | 0.0968 |
Trypanosoma cruzi | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0165 | 0.1889 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0276 | 0.1399 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase alpha chain B | 0.0165 | 0.1889 | 0.1889 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0109 | 0.1163 | 0.3296 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0453 | 0.2343 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0367 | 0.104 |
Brugia malayi | phenylalanyl-tRNA synthetase, mitochondrial precursor, putative | 0.0048 | 0.0366 | 0.1627 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0463 | 0.578 | 0.578 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.1163 | 0.5878 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.0048 | 0.0366 | 0.135 |
Echinococcus granulosus | phenylalanyl tRNA synthetase alpha chain B | 0.0165 | 0.1889 | 0.3269 |
Chlamydia trachomatis | phenylalanine--tRNA ligase subunit alpha | 0.0785 | 0.9974 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.0367 | 0.0367 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0048 | 0.0366 | 0.135 |
Echinococcus granulosus | neuropeptide s receptor | 0.0463 | 0.578 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.1889 | 1 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.0367 | 0.104 |
Brugia malayi | 6-phosphofructokinase | 0.0109 | 0.1163 | 0.6009 |
Toxoplasma gondii | Ferredoxin-fold anticodon binding domain-containing protein | 0.0048 | 0.0366 | 0.135 |
Wolbachia endosymbiont of Brugia malayi | phenylalanyl-tRNA synthetase subunit alpha | 0.0785 | 0.9974 | 0.5 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0048 | 0.0366 | 0.135 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0453 | 0.2108 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0213 | 0.0369 |
Schistosoma mansoni | hypothetical protein | 0.029 | 0.3529 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0014 | 0.0039 |
Trypanosoma brucei | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0165 | 0.1889 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0342 | 0.0591 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0244 | 0.096 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.0367 | 0.0635 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0463 | 0.578 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0109 | 0.1163 | 0.6128 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0342 | 0.0968 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.0367 | 0.0635 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0109 | 0.1163 | 0.6128 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase | 0.0048 | 0.0366 | 0.0366 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0723 | 0.3592 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0342 | 0.0591 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0453 | 0.0784 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0668 | 0.3486 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0048 | 0.0366 | 0.1036 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0109 | 0.1163 | 0.5878 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0453 | 0.1284 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0109 | 0.1163 | 0.5878 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.0367 | 0.5 |
Mycobacterium leprae | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.0117 | 0.1268 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0188 | 0.2198 | 0.2198 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0039 | 0.0039 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0213 | 0.0213 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0188 | 0.2198 | 0.3802 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0048 | 0.0366 | 0.135 |
Plasmodium falciparum | phenylalanine--tRNA ligase alpha subunit | 0.0165 | 0.1889 | 1 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0048 | 0.0366 | 0.135 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0109 | 0.1163 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0245 | 0.1234 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0301 | 0.1532 |
Loa Loa (eye worm) | phosphofructokinase | 0.0109 | 0.1163 | 0.6128 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0453 | 0.2343 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0367 | 0.1883 |
Mycobacterium ulcerans | phenylalanyl-tRNA synthetase subunit alpha | 0.0785 | 0.9974 | 1 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0453 | 0.0784 |
Giardia lamblia | Phenylalanyl-tRNA synthetase alpha chain | 0.0165 | 0.1889 | 1 |
Toxoplasma gondii | phenylalanyl-tRNA synthetase alpha chain A, putative | 0.0165 | 0.1889 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0342 | 0.1494 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0165 | 0.1889 | 1 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0453 | 0.0453 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.1163 | 0.5878 |
Onchocerca volvulus | 0.0048 | 0.0367 | 0.5 | |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0109 | 0.1163 | 0.5878 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0109 | 0.1163 | 0.5878 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0109 | 0.1163 | 0.1163 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase mitochondrial | 0.0048 | 0.0366 | 0.1036 |
Leishmania major | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0165 | 0.1889 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.