Detailed information for compound 1731718

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 572.516 | Formula: C31H24O11
  • H donors: 3 H acceptors: 8 LogP: 3.11 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)[C@@]1(CC(=O)c2c(O1)cc1c(c2O)[C@@H]2C=C[C@]3(C1)C(=C(O)c1c(C3=O)cc(cc1O)C)C2=O)[C@@H]1CCC(=O)O1
  • InChi: 1S/C31H24O11/c1-12-7-15-22(16(32)8-12)27(37)24-25(35)14-5-6-30(24,28(15)38)10-13-9-18-23(26(36)21(13)14)17(33)11-31(42-18,29(39)40-2)19-3-4-20(34)41-19/h5-9,14,19,32,36-37H,3-4,10-11H2,1-2H3/t14-,19-,30-,31+/m0/s1
  • InChiKey: JUSHCXMJWBJGNO-CLEZSSNSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major cathepsin L-like protease 0.0018 0.0177 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0141 0.0636
Loa Loa (eye worm) hypothetical protein 0.0012 0.0056 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0541 0.2446
Loa Loa (eye worm) hypothetical protein 0.0036 0.0547 0.2225
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.1204 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0233 0.0324
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0341 0.1539
Giardia lamblia DINP protein human, muc B family 0.0021 0.0233 0.13
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0541 0.2446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0793 0.3582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0141 0.0636
Plasmodium vivax vivapain-2 0.0018 0.0177 0.0177
Plasmodium falciparum calcium-dependent protein kinase 3 0.0036 0.0547 0.0547
Loa Loa (eye worm) hypothetical protein 0.0035 0.0532 0.2163
Leishmania major DNA polymerase eta, putative 0.0021 0.0233 0.0868
Plasmodium falciparum proline--tRNA ligase 0.0041 0.0651 0.0651
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.0149 0.0199
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0117 0.2212 0.3079
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.09 0.3722
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0233 0.1935
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0035 0.0532 0.2404
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0891 0.4028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Trypanosoma brucei unspecified product 0.0014 0.0102 0.0849
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0177 0.0688
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0532 0.2404
Echinococcus granulosus dna polymerase eta 0.0021 0.0233 0.0324
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.09 0.3692
Mycobacterium ulcerans integral membrane transport protein 0.0016 0.0149 0.2954
Brugia malayi Cathepsin L-like precursor 0.0018 0.0177 0.0733
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0177 0.0801
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0233 0.1935
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0233 0.1935
Leishmania major hypothetical protein, conserved 0.0016 0.0149 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0102 0.0849
Echinococcus multilocularis calcium dependent protein kinase 0.0034 0.0501 0.0698
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0541 0.2446
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma brucei unspecified product 0.0014 0.0102 0.0849
Trypanosoma brucei sugar transporter, putative 0.0016 0.0149 0.124
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0348 0.3046
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0036 0.0547 0.4542
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0651 0.5409
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2212 0.3079
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0149 0.0208
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0177 0.0247
Echinococcus granulosus dna polymerase kappa 0.0021 0.0233 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0793 0.3582
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0177 0.0247
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0547 0.0761
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0035 0.0532 0.074
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0056 0.0255
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0341 0.1539
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0036 0.0547 0.2225
Loa Loa (eye worm) ctsf protein 0.0018 0.0177 0.0688
Trypanosoma cruzi hexose transporter, putative 0.002 0.0219 0.1816
Schistosoma mansoni hypothetical protein 0.0017 0.0156 0.0705
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0348 0.0484
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0233 0.0324
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0348 0.0348
Brugia malayi Cathepsin L-like precursor 0.0018 0.0177 0.0733
Echinococcus multilocularis tumor protein p63 0.036 0.7186 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.019 0.3691 0.5585
Leishmania major cathepsin L-like protease 0.0068 0.1204 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.09 0.3722
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0141 0.0636
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0793 0.6582
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Entamoeba histolytica protein kinase, putative 0.0036 0.0547 0.69
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Brugia malayi Cathepsin L-like precursor 0.0018 0.0177 0.0733
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0547 0.0761
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0066 0.5
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0233 0.1053
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0348 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0793 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Leishmania major glucose transporter/membrane transporter D2, putative 0.0036 0.0556 0.3908
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0793 0.613
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0016 0.0149 0.5
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0651 0.5409
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0056 0.0233
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0276 0.2289
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0018 0.0083
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0547 0.0761
Trypanosoma brucei unspecified product 0.0021 0.0233 0.1935
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0233 0.092
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.019 0.3691 0.3691
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0156 0.06
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0107 0.0398
Toxoplasma gondii sugar transporter ST2 0.0016 0.0149 0.0199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0056 0.0255
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0177 0.2236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Onchocerca volvulus 0.0018 0.0177 0.1447
Brugia malayi Cathepsin L-like precursor 0.0018 0.0177 0.0733
Leishmania major protein kinase, putative 0.0036 0.0547 0.382
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0556 0.2514
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0448 0.2027
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0149 0.0675
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Leishmania major cathepsin L-like protease 0.0068 0.1204 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0556 0.462
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Toxoplasma gondii sugar transporter ST1 0.0016 0.0149 0.0199
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Entamoeba histolytica cysteine protease, putative 0.0018 0.0177 0.2236
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0793 0.6582
Schistosoma mansoni glucose transport protein 0.0117 0.2212 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0592 0.2675
Echinococcus granulosus GPCR family 2 0.0017 0.0156 0.0217
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0541 0.0795
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.0149 0.0081
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0036 0.0547 0.0804
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0556 0.2514
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0793 0.3582
Echinococcus multilocularis General substrate transporter 0.0101 0.1875 0.2609
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0547 0.0761
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Onchocerca volvulus 0.0016 0.0149 0.1113
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0149 0.0675
Loa Loa (eye worm) cysteine protease 0.0018 0.0177 0.0688
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0348 0.1571
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Brugia malayi MH2 domain containing protein 0.0127 0.2417 1
Onchocerca volvulus 0.0016 0.0149 0.1113
Loa Loa (eye worm) hypothetical protein 0.0053 0.09 0.3692
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Schistosoma mansoni glucose transport protein 0.0117 0.2212 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0341 0.1543
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0233 0.7117
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0141 0.0196
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0233 0.1053
Brugia malayi Cathepsin L-like precursor 0.0018 0.0177 0.0733
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0541 0.2446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0649 0.2934
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0233 0.5926
Onchocerca volvulus 0.0016 0.0149 0.1113
Loa Loa (eye worm) hypothetical protein 0.0053 0.0891 0.3656
Brugia malayi Sugar transporter family protein 0.0016 0.0149 0.0618
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0036 0.0547 0.2262
Leishmania major cathepsin L-like protease 0.0018 0.0177 0.0343
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0177 0.2236
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0149 0.0618
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Plasmodium falciparum mitogen-activated protein kinase 2 0.019 0.3691 0.3691
Plasmodium falciparum calcium-dependent protein kinase 4 0.0036 0.0547 0.0547
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0348 1
Echinococcus multilocularis solute carrier family 22 0.0016 0.0149 0.0208
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2212 0.3079
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Schistosoma mansoni glucose transport protein 0.0117 0.2212 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0341 0.1539
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0593 0.4922
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0041 0.0651 0.0962
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Brugia malayi major facilitator superfamily protein 0.0016 0.0149 0.0618
Entamoeba histolytica protein kinase, putative 0.0036 0.0547 0.69
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0592 0.2675
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0102 0.0849
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0149 0.124
Entamoeba histolytica hypothetical protein 0.0026 0.0348 0.4386
Schistosoma mansoni hypothetical protein 0.0036 0.0555 0.2511
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0593 0.4922
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0556 0.2514
Onchocerca volvulus 0.0016 0.0149 0.1113
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0177 0.0688
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0149 0.0675
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0149 0.2954
Schistosoma mansoni hypothetical protein 0.0017 0.0156 0.0705
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0348 0.2887
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0541 0.2446
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0156 0.0217
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0793 0.6582
Onchocerca volvulus 0.0018 0.0177 0.1447
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0177 0.0801
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0906 0.7525
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0056 0.0711
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0177 0.0247
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0556 0.462
Brugia malayi Sugar transporter family protein 0.0117 0.2212 0.9152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0397 0.1602
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0793 0.3279
Echinococcus granulosus General substrate transporter 0.0101 0.1875 0.2609
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Leishmania major glucose transporter, lmgt3 0.0036 0.0556 0.3908
Schistosoma mansoni hypothetical protein 0.0117 0.2212 1
Onchocerca volvulus 0.0016 0.0149 0.1113
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma cruzi hexose transporter 0.0036 0.0556 0.462
Schistosoma mansoni protein kinase 0.0036 0.0547 0.2472
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0035 0.0532 0.074
Onchocerca volvulus 0.0018 0.0177 0.1447
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Plasmodium vivax vivapain-2 0.0018 0.0177 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0102 0.0849
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0156 0.0645
Echinococcus granulosus tumor protein p63 0.036 0.7186 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.1204 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0233 0.1053
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0348 0.1946
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0233 0.1935
Schistosoma mansoni sugar transporter 0.0016 0.0149 0.0675
Schistosoma mansoni sugar transporter 0.0016 0.0149 0.0675
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0177 0.0801
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2212 0.3079
Leishmania major glucose transporter, lmgt1 0.0036 0.0556 0.3908
Toxoplasma gondii cathepsin CPL 0.0018 0.0177 0.0241
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0593 0.4251
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0036 0.0547 0.0547
Onchocerca volvulus 0.0016 0.0149 0.1113
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0177 0.1447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0341 0.1543
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.1204 1
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0149 0.0208
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0177 0.0247
Brugia malayi Cathepsin L-like precursor 0.0012 0.0056 0.0233
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Mycobacterium ulcerans sugar transporter 0.0016 0.0149 0.2954
Schistosoma mansoni protein kinase 0.0036 0.0547 0.2472
Brugia malayi Cathepsin L-like precursor 0.0018 0.0177 0.0733
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0177 0.1447
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0177 0.1447
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0556 0.2514
Loa Loa (eye worm) hypothetical protein 0.0026 0.0348 0.1397
Echinococcus granulosus solute carrier family 22 0.0016 0.0149 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Onchocerca volvulus 0.0016 0.0149 0.1113
Trichomonas vaginalis myo-inositol transporter, putative 0.0016 0.0149 0.0675
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0793 0.1103
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0348 0.1438
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0341 0.1543
Schistosoma mansoni glucose transporter 0.0016 0.0149 0.0675
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0547 0.0761
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0392 0.1772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0547 0.2472
Onchocerca volvulus 0.0053 0.0891 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0028
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0141 0.0636
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0149 0.124
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0348 0.1571
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Onchocerca volvulus 0.0018 0.0177 0.1447
Leishmania major DNA polymerase kappa, putative 0.0021 0.0233 0.0868
Trypanosoma brucei glucose transporter 1E 0.0036 0.0556 0.462
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0233 0.0868
Onchocerca volvulus 0.0016 0.0149 0.1113
Trichomonas vaginalis sugar transport protein, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0556 0.2514
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0036 0.0547 0.2225
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0556 0.462
Plasmodium falciparum calcium-dependent protein kinase 2 0.0036 0.0547 0.0547
Loa Loa (eye worm) hypothetical protein 0.0012 0.0056 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0547 0.2472
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0141 0.0582
Onchocerca volvulus 0.0016 0.0149 0.1113
Echinococcus multilocularis cysteine protease 0.0018 0.0177 0.0247
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0036 0.0547 0.0547
Echinococcus granulosus solute carrier family 22 0.0016 0.0149 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0348 0.1571
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0547 0.0761
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Echinococcus granulosus cathepsin l1 0.0012 0.0056 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0592 0.2675
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0149 0.124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.0149 0.124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0056 0.0255
Onchocerca volvulus 0.0016 0.0149 0.1113
Schistosoma mansoni sugar transporter 0.0016 0.0149 0.0675
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0149 0.0675
Echinococcus multilocularis GPCR, family 2 0.0017 0.0156 0.0217
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Leishmania major cathepsin L-like protease 0.0018 0.0177 0.0343
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0793 0.3246
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.2417 1
Plasmodium vivax hexose transporter 0.0117 0.2212 0.2212
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0177 0.0801
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0149 0.0572
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0348 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0149 0.0675
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Leishmania major cathepsin L-like protease 0.0018 0.0177 0.0343
Brugia malayi hypothetical protein 0.0016 0.0149 0.0618
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0233 0.0964
Schistosoma mansoni hypothetical protein 0.0017 0.0156 0.0705
Toxoplasma gondii facilitative glucose transporter GT1 0.0117 0.2212 0.3336
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0149 0.0208
Loa Loa (eye worm) hypothetical protein 0.0018 0.0177 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0398 0.1798
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.1204 1
Brugia malayi hypothetical protein 0.0016 0.0149 0.0618
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0233 0.1935
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.2212 1
Leishmania major glucose transporter, lmgt2 0.0036 0.0556 0.3908
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.0149 0.0149
Onchocerca volvulus 0.0016 0.0149 0.1113
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0793 0.3582
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0036 0.0547 0.0547
Onchocerca volvulus 0.0016 0.0149 0.1113
Schistosoma mansoni DNA polymerase eta 0.0021 0.0233 0.1053
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0141 0.0196
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0793 0.6582
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2212 0.3079
Leishmania major cathepsin L-like protease 0.0018 0.0177 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0556 0.462
Echinococcus multilocularis solute carrier family 22 0.0016 0.0149 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0556 0.2514
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0141 0.1168
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0035 0.0532 0.2201
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0547 0.0547
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0233 0.7117
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2212 0.3079
Onchocerca volvulus 0.0018 0.0177 0.1447
Plasmodium falciparum hexose transporter 0.0117 0.2212 0.2212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0541 0.2446
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0036 0.0547 0.0761
Onchocerca volvulus Putative transporter 0.0016 0.0149 0.1113
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0177 0.0177
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0149 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0156 0.06
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0282 0.1273
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0398 0.1798
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0016 0.0149 0.2954
Brugia malayi major facilitator superfamily protein 0.0016 0.0149 0.0618
Onchocerca volvulus 0.0016 0.0149 0.1113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0592 0.2675
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0141 0.1168
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0547 0.0761
Loa Loa (eye worm) hypothetical protein 0.0036 0.0555 0.2261
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0651 0.5409
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Schistosoma mansoni protein kinase 0.0036 0.0547 0.2472
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0233 0.5926
Toxoplasma gondii sugar transporter ST3 0.0016 0.0149 0.0199
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0219 0.182
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0149 0.0675
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0233 0.0964
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0156 0.0217
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0348 0.2887
Loa Loa (eye worm) sugar transporter 0.0117 0.2212 0.9148
Echinococcus multilocularis solute carrier family 22 0.0016 0.0149 0.0208
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0035 0.0532 0.2201
Plasmodium vivax CDK-related protein kinase 6, putative 0.0498 1 1
Echinococcus granulosus solute carrier family 22 0.0016 0.0149 0.0208
Onchocerca volvulus 0.0018 0.0177 0.1447
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0233 0.0324
Plasmodium vivax sugar transporter, putative 0.0016 0.0149 0.0149
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2212 0.3079
Echinococcus multilocularis dna polymerase eta 0.0021 0.0233 0.0324
Loa Loa (eye worm) hypothetical protein 0.0012 0.0056 0.0186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.047 0.2123
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2212 0.3079
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0177 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0177 0.0801
Schistosoma mansoni hypothetical protein 0.0017 0.0156 0.0705
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0651 0.4802
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Trichomonas vaginalis glucose transporter, putative 0.0016 0.0149 0.0675
Trypanosoma brucei glucose transporter, putative 0.0036 0.0556 0.462
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0177 0.1472
Plasmodium falciparum calcium-dependent protein kinase 1 0.0036 0.0547 0.0547
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0233 0.2939
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Brugia malayi Sugar transporter family protein 0.0016 0.0149 0.0618
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0267 1
Loa Loa (eye worm) sugar transporter 0.0016 0.0149 0.0572
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0035 0.0532 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0398 0.1798
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Echinococcus granulosus calcium dependent protein kinase 0.0034 0.0501 0.0698
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0177 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0592 0.2675
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0036 0.0547 0.0804
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0267 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0233 0.1935
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0035 0.0532 0.6712
Giardia lamblia GTOR 0.0048 0.0793 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Echinococcus multilocularis solute carrier family 22 0.0016 0.0149 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0541 0.2446
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0177 0.0733
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0233 0.1053
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0149 0.0618
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0348 0.3083
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0555 0.2298
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0341 0.1543
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Giardia lamblia Prolyl-tRNA synthetase 0.0035 0.0532 0.5949
Brugia malayi Cam kinase protein 1 0.0036 0.0547 0.2262
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.2417 1
Plasmodium falciparum protein kinase 7 0.0331 0.6594 0.6594
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0177 0.0801
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0036 0.0547 0.0804
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0392 0.1772
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0141 0.0536
Onchocerca volvulus 0.0016 0.0149 0.1113
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0348 0.0348
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Echinococcus multilocularis cysteine protease 0.0018 0.0177 0.0247
Brugia malayi hypothetical protein 0.0016 0.0149 0.0618
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0556 0.462
Echinococcus granulosus cathepsin l1 0.0018 0.0177 0.0247
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0348 0.0501
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0141 0.1168
Onchocerca volvulus 0.0016 0.0149 0.1113
Schistosoma mansoni sugar transporter 0.0016 0.0149 0.0675
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0793 0.613
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0177 0.0177
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0156 0.0217
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0651 0.4802
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0156 0.0645
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0149 0.0675
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0556 0.462
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0149 0.0572
Brugia malayi Cathepsin L-like precursor 0.0012 0.0056 0.0233
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0177 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0141 0.0636
Loa Loa (eye worm) fibroinase 0.0018 0.0177 0.0688
Plasmodium vivax proline--tRNA ligase, putative 0.0041 0.0651 0.0651
Loa Loa (eye worm) hypothetical protein 0.0016 0.0149 0.0572
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0156 0.0217
Toxoplasma gondii protein kinase, putative 0.0331 0.6594 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.1083 0.8997
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0348 1
Trypanosoma brucei glucose transporter 2A 0.0036 0.0556 0.462
Loa Loa (eye worm) hypothetical protein 0.0021 0.0233 0.092
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0793 0.1103
Onchocerca volvulus 0.0016 0.0149 0.1113
Brugia malayi cathepsin L-like precursor 0.0012 0.0056 0.0233
Loa Loa (eye worm) hypothetical protein 0.0035 0.0532 0.2163
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0149 0.0618
Onchocerca volvulus 0.0018 0.0177 0.1447
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.1204 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0141 0.1168
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0532 0.2404
Echinococcus granulosus solute carrier family 22 0.0016 0.0149 0.0208
Plasmodium falciparum calcium-dependent protein kinase 5 0.0036 0.0547 0.0547
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0793 1
Leishmania major cathepsin L-like protease 0.0068 0.1204 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0141 0.0636
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0556 0.2514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0075 0.0339

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 15.49 uM Cytotoxicity against human SW480 assessed as cell viability measured after 48 hrs by MTT assay ChEMBL. 23586920

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 23586920

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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