Detailed information for compound 1732915

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 466.566 | Formula: C28H34O6
  • H donors: 1 H acceptors: 3 LogP: 3.17 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)O[C@H]1C[C@H]2[C@@](C3=CC[C@H]([C@]13C)c1cocc1)(C)[C@H](O)[C@H]1[C@@H]3[C@]2(C)C(=O)C=C[C@@]3(C)CO1
  • InChi: 1S/C28H34O6/c1-15(29)34-21-12-19-27(4,18-7-6-17(26(18,21)3)16-9-11-32-13-16)24(31)22-23-25(2,14-33-22)10-8-20(30)28(19,23)5/h7-11,13,17,19,21-24,31H,6,12,14H2,1-5H3/t17-,19-,21-,22+,23-,24+,25-,26-,27-,28-/m0/s1
  • InChiKey: PCOIBLURWHFKMR-XWQWWSFPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cytochrome P450 family protein 0.004 0.0898 0.095
Echinococcus multilocularis SH2 motif 0.0128 0.4056 0.429
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Echinococcus granulosus dna polymerase kappa 0.0077 0.2231 0.236
Echinococcus multilocularis retinal guanylyl cyclase 2 0.009 0.2684 0.2839
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.009 0.2684 0.2839
Loa Loa (eye worm) TK/KIN16 protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Leishmania major DNA polymerase kappa, putative 0.0058 0.1533 0.1533
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Giardia lamblia Kinase, NEK 0.009 0.2684 1
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0217 0.7292 0.7713
Echinococcus granulosus retinal guanylyl cyclase 2 0.009 0.2684 0.2839
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0957 0.0957
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.009 0.2684 0.2839
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Echinococcus granulosus tyrosine protein kinase pr2 0.009 0.2684 0.2839
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0083 0.2463 0.8532
Leishmania major DNA damage repair protein, putative 0.0016 0.0023 0.0023
Schistosoma mansoni SH2A 0.0128 0.4056 0.4508
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Schistosoma mansoni DNA polymerase IV / kappa 0.0016 0.0023 0.0026
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.077 0.1537
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Echinococcus multilocularis calpain family protein 1, d 0.004 0.0898 0.095
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Trichomonas vaginalis AGC family protein kinase 0.009 0.2684 0.2692
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0358 0.0358
Echinococcus granulosus growth factor receptor bound protein 2 0.0128 0.4056 0.429
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.009 0.2684 0.2839
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.077 0.2868
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0375 0.002
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0329 0.1225
Schistosoma mansoni src-type protein tyrosine kinase-related 0.009 0.2684 0.2983
Brugia malayi Receptor family ligand binding region containing protein 0.009 0.2684 0.2839
Echinococcus multilocularis natriuretic peptide receptor 1 0.009 0.2684 0.2839
Trichomonas vaginalis conserved hypothetical protein 0.009 0.2684 0.2692
Schistosoma mansoni DNA polymerase eta 0.0076 0.2192 0.2436
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0062 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Schistosoma mansoni serine/threonine protein kinase 0.009 0.2684 0.2983
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.009 0.2684 0.2692
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0898 0.095
Echinococcus granulosus tyrosine protein kinase csk 0.009 0.2684 0.2839
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Brugia malayi calpain 7 0.0017 0.0062 0.0066
Echinococcus multilocularis retinal guanylyl cyclase 2 0.009 0.2684 0.2839
Brugia malayi Raf kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0217 0.7292 0.7713
Echinococcus multilocularis inositol monophosphatase 1 0.0033 0.0632 0.0668
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Trypanosoma brucei Flagellum attachment zone protein 20 0.009 0.2684 0.2684
Onchocerca volvulus 0.009 0.2684 0.3338
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Echinococcus multilocularis insulin receptor 0.009 0.2684 0.2839
Schistosoma mansoni tensin 0.0128 0.4056 0.4508
Echinococcus multilocularis tyrosine protein kinase csk 0.009 0.2684 0.2839
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0787 0.0833
Plasmodium vivax calpain, putative 0.0017 0.0062 0.0232
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0033 0.0632 0.2354
Schistosoma mansoni tyrosine kinase 0.0217 0.7292 0.8104
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Onchocerca volvulus 0.0128 0.4056 0.5322
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Entamoeba histolytica cysteine surface protein, putative 0.009 0.2684 0.3626
Brugia malayi tRNA modification GTPase TrmE family protein 0.0128 0.4056 0.429
Trypanosoma brucei antigen, putative 0.0017 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Mycobacterium ulcerans glutaminase 0.0264 0.8999 1
Schistosoma mansoni tyrosine kinase 0.0217 0.7292 0.8104
Brugia malayi SH2 domain containing protein 0.0128 0.4056 0.429
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.009 0.2684 0.2839
Loa Loa (eye worm) SRC-1 0.0217 0.7292 0.7713
Trypanosoma brucei protein kinase, putative 0.009 0.2684 0.2684
Loa Loa (eye worm) hypothetical protein 0.0076 0.2192 0.2319
Plasmodium falciparum metacaspase-like protein 0.0026 0.0375 0.1398
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0062 0.1674 0.5088
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0128 0.4056 0.429
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Brugia malayi SH2 domain containing protein 0.0128 0.4056 0.429
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.2799 0.5592
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Echinococcus multilocularis dna polymerase kappa 0.0077 0.2231 0.236
Loa Loa (eye worm) TK/INSR protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0632 0.0632
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0375 0.1398
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0128 0.4056 0.5524
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.006 0.1618 0.1798
Trichomonas vaginalis conserved hypothetical protein 0.009 0.2684 0.2692
Echinococcus multilocularis protein kinase 0.009 0.2684 0.2839
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.009 0.2684 0.2839
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0128 0.4085 0.4525
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0023 0.0023
Trichomonas vaginalis serine-threonine protein kinase, putative 0.009 0.2684 0.2692
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Echinococcus granulosus SHC transforming protein 3 0.0128 0.4056 0.429
Echinococcus multilocularis 0.0128 0.4056 0.429
Loa Loa (eye worm) hypothetical protein 0.0026 0.0375 0.0397
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0128 0.4056 0.4508
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0128 0.4056 0.429
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.2684 0.2839
Brugia malayi calpain family protein 1 0.0057 0.1513 0.16
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0128 0.4056 0.429
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Mycobacterium tuberculosis Probable reductase 0.0083 0.2463 0.492
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0358 0.0358
Brugia malayi ephrin receptor 1 precursor 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0128 0.4056 0.429
Echinococcus granulosus activated cdc42 kinase 1 0.009 0.2684 0.2839
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0128 0.4056 0.429
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.009 0.2684 0.2839
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Brugia malayi Protein kinase domain containing protein 0.0217 0.7292 0.7713
Schistosoma mansoni tyrosine-protein kinase fps85d 0.009 0.2684 0.2983
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Echinococcus multilocularis geminin 0.0164 0.5368 0.5678
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Trichomonas vaginalis protein kinase atn1, putative 0.009 0.2684 0.2692
Loa Loa (eye worm) hypothetical protein 0.0042 0.0953 0.1007
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0957 0.0957
Onchocerca volvulus 0.0128 0.4056 0.5322
Trypanosoma brucei Pseudokinase, putative 0.009 0.2684 0.2684
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Echinococcus granulosus tyrosine protein kinase shark 0.0217 0.7292 0.7713
Brugia malayi hypothetical protein 0.0217 0.7292 0.7713
Schistosoma mansoni hypothetical protein 0.0164 0.5368 0.5966
Trypanosoma brucei unspecified product 0.0035 0.0727 0.0727
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0705 0.0746
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Onchocerca volvulus 0.009 0.2684 0.3338
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0029 0.0508 0.1014
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 1 1
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0632 0.0632
Plasmodium vivax glutathione reductase, putative 0.0037 0.077 0.2868
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0953 0.0953
Leishmania major DNA polymerase eta, putative 0.0076 0.2192 0.2192
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis caspase 0.0026 0.0375 0.0397
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.009 0.2684 0.3626
Echinococcus granulosus expressed conserved protein 0.0128 0.4056 0.429
Echinococcus multilocularis N chimaerin 0.0128 0.4056 0.429
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.2799 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.009 0.2684 0.2839
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Schistosoma mansoni hypothetical protein 0.0035 0.0705 0.0783
Echinococcus granulosus epidermal growth factor receptor 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0914 0.0914
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.006 0.1618 0.1798
Loa Loa (eye worm) hypothetical protein 0.0085 0.2527 0.2672
Loa Loa (eye worm) hypothetical protein 0.0085 0.2527 0.2672
Echinococcus multilocularis SHC transforming protein 3 0.0128 0.4056 0.429
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.009 0.2684 0.2839
Trypanosoma cruzi metacaspase, putative 0.0026 0.0375 0.0375
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Mycobacterium ulcerans DNA polymerase IV 0.0077 0.2231 0.246
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Trypanosoma brucei metacaspase MCA3 0.0026 0.0375 0.0375
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Trichomonas vaginalis conserved hypothetical protein 0.009 0.2684 0.2692
Loa Loa (eye worm) calpain 5 0.0017 0.0062 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Toxoplasma gondii hypothetical protein 0.0047 0.115 0.4284
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.009 0.2684 0.2839
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Schistosoma mansoni hypothetical protein 0.0128 0.4056 0.4508
Echinococcus granulosus tyrosine kinase 0.009 0.2684 0.2839
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0787 0.0833
Brugia malayi hypothetical protein 0.009 0.2684 0.2839
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0128 0.4056 0.429
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.009 0.2684 0.2839
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0217 0.7292 0.7713
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0957 0.0957
Echinococcus multilocularis fibroblast growth factor receptor 4 0.009 0.2684 0.2839
Trichomonas vaginalis STE family protein kinase 0.009 0.2684 0.2692
Loa Loa (eye worm) TK/DDR protein kinase 0.009 0.2684 0.2839
Plasmodium vivax metacaspase 1, putative 0.0026 0.0375 0.1398
Echinococcus multilocularis protein tyrosine kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica ankyrin repeat protein 0.009 0.2684 0.3626
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0051 0.1302 0.1377
Loa Loa (eye worm) TK/EPH protein kinase 0.009 0.2684 0.2839
Mycobacterium ulcerans hypothetical protein 0.0154 0.5006 0.5551
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.009 0.2684 0.2839
Trichomonas vaginalis conserved hypothetical protein 0.009 0.2684 0.2692
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0932 0.0932
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Leishmania major kinesin, putative 0.0017 0.0062 0.0062
Echinococcus multilocularis activated cdc42 kinase 1 0.009 0.2684 0.2839
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.2684 0.2839
Leishmania major hypothetical protein, conserved 0.009 0.2684 0.2684
Echinococcus multilocularis heat shock protein 70 0.009 0.2684 0.2839
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Giardia lamblia Protein 21.1 0.009 0.2684 1
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0375 0.0417
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Loa Loa (eye worm) RGC/RGC protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Brugia malayi Tyrosine-protein kinase PR2 0.009 0.2684 0.2839
Onchocerca volvulus 0.009 0.2684 0.3338
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0217 0.7292 0.7713
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Echinococcus granulosus receptor type guanylyl cyclase 0.009 0.2684 0.2839
Echinococcus granulosus muscleblind protein 0.0277 0.9455 1
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica receptor protein kinase, putative 0.009 0.2684 0.3626
Mycobacterium ulcerans lipoprotein LpqF 0.0062 0.1674 0.1838
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.009 0.2684 0.2684
Echinococcus multilocularis retinal guanylyl cyclase 2 0.009 0.2684 0.2839
Echinococcus granulosus SH2 motif 0.0128 0.4056 0.429
Echinococcus granulosus kinase suppressor of Ras 1 0.009 0.2684 0.2839
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus insulin growth factor 1 receptor beta 0.009 0.2684 0.2839
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis FL cytokine receptor 0.009 0.2684 0.2839
Trichomonas vaginalis DNA polymerase eta, putative 0.0077 0.2231 0.2168
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Echinococcus granulosus calpain 5 0.0017 0.0062 0.0066
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Echinococcus granulosus fibroblast growth factor receptor 4 0.009 0.2684 0.2839
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0217 0.7292 0.7713
Loa Loa (eye worm) TK/ROR protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni protein tyrosine kinase 0.009 0.2684 0.2983
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Plasmodium falciparum thioredoxin reductase 0.0037 0.077 0.2868
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Loa Loa (eye worm) protein kinase domain-containing protein 0.009 0.2684 0.2839
Entamoeba histolytica serine/threonine kinase, putative 0.009 0.2684 0.3626
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Echinococcus multilocularis tensin 0.0128 0.4056 0.429
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0128 0.4056 0.429
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.2799 0.5592
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Echinococcus multilocularis muscleblind protein 0.0277 0.9455 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.1513 0.16
Echinococcus multilocularis epidermal growth factor receptor 0.009 0.2684 0.2839
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0022 0.0254 0.0946
Echinococcus multilocularis dna polymerase eta 0.0076 0.2192 0.2319
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.009 0.2684 0.2839
Brugia malayi Guanylyl cyclase protein 23 0.009 0.2684 0.2839
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Entamoeba histolytica serine/threonine kinase, putative 0.009 0.2684 0.3626
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Brugia malayi STAT protein, DNA binding domain containing protein 0.0128 0.4056 0.429
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0062 0.0062
Toxoplasma gondii thioredoxin reductase 0.0037 0.077 0.2868
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Loa Loa (eye worm) hypothetical protein 0.0277 0.9455 1
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica tyrosin kinase, putative 0.009 0.2684 0.3626
Echinococcus granulosus SH2 domain containing protein 7 0.0128 0.4056 0.429
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0033 0.0632 0.0317
Echinococcus granulosus tyrosine protein kinase csk 0.009 0.2684 0.2839
Entamoeba histolytica hypothetical protein 0.009 0.2688 0.3632
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.009 0.2684 0.2839
Trypanosoma brucei unspecified product 0.0035 0.0727 0.0727
Echinococcus granulosus SH2 domain containing adapter protein F 0.0128 0.4056 0.429
Echinococcus multilocularis tyrosine protein kinase HCK 0.009 0.2684 0.2839
Echinococcus granulosus tyrosine protein kinase ABL1 0.0217 0.7292 0.7713
Echinococcus multilocularis tyrosine protein kinase csk 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0062 0.0062
Trypanosoma cruzi protein kinase, putative 0.009 0.2684 0.2684
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.1302 0.1377
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0358 0.1257
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0632 0.0632
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0062 0.1674 0.3343
Brugia malayi Protein kinase domain containing protein 0.0217 0.7292 0.7713
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.009 0.2684 1
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Schistosoma mansoni shc transforming protein 0.0128 0.4056 0.4508
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni nck2/grb4 0.0128 0.4056 0.4508
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0083 0.2463 0.492
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0062 0.0062
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Entamoeba histolytica protein kinase, putative 0.009 0.2688 0.3632
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0358 0.0378
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0023 0.0023
Echinococcus granulosus N chimaerin 0.0128 0.4056 0.429
Brugia malayi Variant SH3 domain containing protein 0.0128 0.4056 0.429
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Plasmodium falciparum protein kinase, putative 0.009 0.2684 1
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Loa Loa (eye worm) RGC/RGC protein kinase 0.009 0.2684 0.2839
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0128 0.4056 0.429
Echinococcus multilocularis transfer RNA-Thr 0.009 0.2684 0.2839
Brugia malayi SH2 domain containing protein 0.0128 0.4056 0.429
Trypanosoma brucei metacaspase 0.0026 0.0375 0.0375
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0062 0.0062
Trypanosoma brucei metacaspase MCA2 0.0026 0.0375 0.0375
Schistosoma mansoni calpain C (C02 family) 0.0017 0.0062 0.0069
Schistosoma mansoni GTPase activating protein 0.0128 0.4056 0.4508
Trypanosoma brucei Metacaspase-4 0.0026 0.0375 0.0375
Trypanosoma brucei calpain-like protein, putative 0.0017 0.0062 0.0062
Loa Loa (eye worm) TK/FAK protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0217 0.7292 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.009 0.2684 0.2983
Schistosoma mansoni calpain-7 (C02 family) 0.0017 0.0062 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Echinococcus granulosus suppressor of cytokine signaling 6 0.0128 0.4056 0.429
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.1302 0.2601
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0062 0.0062
Plasmodium falciparum metacaspase 1 0.0026 0.0375 0.1398
Loa Loa (eye worm) TK protein kinase 0.0217 0.7292 0.7713
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Brugia malayi glutathione reductase 0.0037 0.077 0.0814
Trichomonas vaginalis inositol monophosphatase, putative 0.0033 0.0632 0.0317
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Brugia malayi Tensin 0.0128 0.4056 0.429
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Leishmania major protein kinase, putative 0.009 0.2684 0.2684
Schistosoma mansoni tensin 0.0128 0.4056 0.4508
Echinococcus granulosus raf serine:threonine protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Echinococcus granulosus tyrosine protein kinase Src64B 0.0217 0.7292 0.7713
Echinococcus granulosus insulin receptor 0.009 0.2684 0.2839
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0033 0.0632 0.0317
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.2684 0.2839
Schistosoma mansoni vav2 0.0128 0.4056 0.4508
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis dual specificity testis specific protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus retinal guanylyl cyclase 2 0.009 0.2684 0.2839
Schistosoma mansoni growth factor receptor-bound protein 0.0128 0.4056 0.4508
Trichomonas vaginalis conserved hypothetical protein 0.009 0.2684 0.2692
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0375 0.002
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0026 0.0375 0.0397
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni suppressor of cytokine signaling 0.0128 0.4056 0.4508
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 1 1
Schistosoma mansoni Mername-AA248 (C02 family) 0.0017 0.0062 0.0069
Brugia malayi Probable tyrosine-protein kinase kin-31 0.009 0.2684 0.2839
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 1 1
Loa Loa (eye worm) serine/threonine protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.009 0.2684 0.2839
Plasmodium vivax tyrosine kinase-like protein, putative 0.009 0.2684 1
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Echinococcus granulosus natriuretic peptide receptor 1 0.009 0.2684 0.2839
Plasmodium falciparum tyrosine kinase-like protein 0.009 0.2684 1
Echinococcus granulosus activin receptor type 0.009 0.2684 0.2839
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0026 0.0375 0.0397
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0358 0.0358
Echinococcus multilocularis SH2 motif 0.0128 0.4056 0.429
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Schistosoma mansoni eyes absent homolog 0.0085 0.2527 0.2808
Entamoeba histolytica hypothetical protein 0.009 0.2688 0.3632
Brugia malayi SH2 domain containing protein 0.0128 0.4056 0.429
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Brugia malayi hypothetical protein 0.0085 0.2527 0.2672
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.009 0.2684 0.2692
Brugia malayi SH2 domain containing protein 0.0128 0.4056 0.429
Schistosoma mansoni glutaminase 0.0264 0.8999 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0217 0.7292 0.7713
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Brugia malayi Inositol-1 0.0033 0.0632 0.0668
Schistosoma mansoni calpain-7 (C02 family) 0.0017 0.0062 0.0069
Brugia malayi C-terminal src kinase protein 1 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0128 0.4056 0.429
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0329 0.1225
Brugia malayi cytokine inducible SH2-containing protein 5 0.0128 0.4056 0.429
Schistosoma mansoni hypothetical protein 0.0164 0.5368 0.5966
Loa Loa (eye worm) SH2 domain-containing protein 0.0128 0.4056 0.429
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Loa Loa (eye worm) SH2 domain-containing protein 0.0128 0.4056 0.429
Leishmania major DNA polymerase kappa, putative 0.0016 0.0023 0.0023
Entamoeba histolytica tyrosin kinase, putative 0.009 0.2684 0.3626
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.009 0.2684 0.2684
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Loa Loa (eye worm) TK/ABL protein kinase 0.0217 0.7292 0.7713
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0128 0.4056 0.429
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0375 0.0375
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0077 0.2231 0.2168
Loa Loa (eye worm) glutathione reductase 0.0037 0.077 0.0814
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.4442 0.4442
Brugia malayi protein-tyrosine kinase 0.0217 0.7292 0.7713
Brugia malayi hypothetical protein 0.0146 0.4728 0.5
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Echinococcus granulosus tyrosine protein kinase Srms 0.0217 0.7292 0.7713
Brugia malayi Tyrosine-protein kinase abl-1 0.0217 0.7292 0.7713
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.2192 0.2192
Loa Loa (eye worm) TK/Met protein kinase 0.009 0.2684 0.2839
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0329 0.1225
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Brugia malayi hypothetical protein 0.0035 0.0705 0.0746
Echinococcus granulosus SH2 motif 0.0128 0.4056 0.429
Echinococcus multilocularis tyrosine protein kinase csk 0.009 0.2684 0.2839
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.077 0.077
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0023 0.0023
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.009 0.2688 0.3632
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0051 0.1302 0.1377
Schistosoma mansoni tyrosine protein kinase 0.009 0.2684 0.2983
Brugia malayi Variant SH3 domain containing protein 0.0128 0.4056 0.429
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Entamoeba histolytica serine/threonine kinase, putative 0.009 0.2684 0.3626
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Schistosoma mansoni tyrosine-protein kinase fps85d 0.009 0.2684 0.2983
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Echinococcus multilocularis tyrosine protein kinase csk 0.009 0.2684 0.2839
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Loa Loa (eye worm) inositol-1 0.0033 0.0632 0.0668
Echinococcus multilocularis NCK adaptor protein 0.0128 0.4056 0.429
Schistosoma mansoni serine/threonine protein kinase 0.009 0.2684 0.2983
Brugia malayi Flap endonuclease-1 0.0025 0.0358 0.0378
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0358 0.1333
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Brugia malayi calpain 5 0.0017 0.0062 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Trypanosoma cruzi metacaspase, putative 0.0026 0.0375 0.0375
Schistosoma mansoni serine/threonine protein kinase 0.009 0.2684 0.2983
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0128 0.4056 0.429
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Entamoeba histolytica receptor protein kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis protein KINase family member (kin 25) 0.009 0.2684 0.2839
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.077 0.0814
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Entamoeba histolytica ankyrin repeat protein 0.009 0.2684 0.3626
Onchocerca volvulus 0.0217 0.7292 1
Onchocerca volvulus 0.009 0.2684 0.3338
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0128 0.4056 0.429
Echinococcus granulosus activated cdc42 kinase 1 0.009 0.2684 0.2839
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Schistosoma mansoni adapter molecule crk 0.0128 0.4056 0.4508
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Echinococcus multilocularis receptor type guanylyl cyclase 0.009 0.2684 0.2839
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.4442 0.4442
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.1533 0.3062
Loa Loa (eye worm) TK/ALK protein kinase 0.009 0.2684 0.2839
Echinococcus granulosus retinal guanylyl cyclase 2 0.009 0.2684 0.2839
Echinococcus multilocularis muscleblind protein 1 0.0277 0.9455 1
Trypanosoma cruzi kinesin, putative 0.0017 0.0062 0.0062
Loa Loa (eye worm) TK/RYK protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.1513 0.1681
Toxoplasma gondii protein kinase domain-containing protein 0.009 0.2684 1
Echinococcus granulosus caspase 8 0.0026 0.0375 0.0397
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.009 0.2684 0.3338
Brugia malayi hypothetical protein 0.0016 0.0017 0.0018
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Schistosoma mansoni serine/threonine protein kinase 0.009 0.2684 0.2983
Plasmodium vivax protein kinase, putative 0.009 0.2684 1
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.006 0.1618 0.1712
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0375 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Echinococcus multilocularis integrin linked protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica protein kinase, putative 0.0128 0.4056 0.5524
Echinococcus granulosus calpain 0.0017 0.0062 0.0066
Echinococcus granulosus dna polymerase eta 0.0076 0.2192 0.2319
Schistosoma mansoni ephrin receptor 0.009 0.2684 0.2983
Echinococcus multilocularis calpain 7 (C02 family) 0.0017 0.0062 0.0066
Trypanosoma brucei trypanothione reductase 0.0037 0.077 0.077
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Brugia malayi bone morphogenetic protein type 1 receptor 0.009 0.2684 0.2839
Echinococcus multilocularis tyrosine protein kinase 0.009 0.2684 0.2839
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.2231 0.2231
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Schistosoma mansoni ephrin receptor 0.009 0.2684 0.2983
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.009 0.2684 0.2839
Entamoeba histolytica tyrosin kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.009 0.2684 0.2839
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Leishmania major metacaspase, putative 0.0026 0.0375 0.0375
Trichomonas vaginalis protein tyrosine kinase, putative 0.009 0.2684 0.2692
Schistosoma mansoni hypothetical protein 0.009 0.2684 0.2983
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0217 0.7292 0.7713
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Echinococcus multilocularis raf serine:threonine protein kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.009 0.2684 0.2684
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.009 0.2684 0.2839
Trichomonas vaginalis glutaminase, putative 0.0264 0.8999 1
Echinococcus multilocularis calpain 0.0017 0.0062 0.0066
Entamoeba histolytica hypothetical protein 0.0035 0.0705 0.0889
Brugia malayi calpain family protein 1 0.0057 0.1513 0.16
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.1533 0.1533
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Echinococcus granulosus hypothetical protein 0.0128 0.4056 0.429
Loa Loa (eye worm) TK/EGFR protein kinase 0.009 0.2684 0.2839
Onchocerca volvulus 0.009 0.2684 0.3338
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.006 0.1618 0.1712
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0128 0.4056 0.429
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0023 0.0023
Echinococcus granulosus tyrosine protein kinase 0.009 0.2684 0.2839
Giardia lamblia DINP protein human, muc B family 0.0058 0.1533 0.5673
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0023 0.0023
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0128 0.4056 0.429
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.1533 0.1533
Entamoeba histolytica serine/threonine kinase, putative 0.009 0.2684 0.3626
Schistosoma mansoni tensin-related 0.0128 0.4056 0.4508
Loa Loa (eye worm) hypothetical protein 0.004 0.0898 0.095
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0128 0.4056 0.429
Loa Loa (eye worm) SH2 domain-containing protein 0.0128 0.4056 0.429
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Loa Loa (eye worm) calpain family protein 1 0.004 0.0898 0.095
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Entamoeba histolytica deoxycytidyl transferase, putative 0.0051 0.1302 0.1715
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Echinococcus granulosus calpain A 0.0017 0.0062 0.0066
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.009 0.2684 0.2839
Onchocerca volvulus 0.0217 0.7292 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.004 0.0898 0.095
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Leishmania major DNA polymerase eta, putative 0.0041 0.0914 0.0914
Onchocerca volvulus 0.0217 0.7292 1
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis caspase 2 0.0026 0.0375 0.0397
Onchocerca volvulus 0.0128 0.4056 0.5322
Brugia malayi Protein kinase domain containing protein 0.0217 0.7292 0.7713
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0128 0.4056 0.429
Brugia malayi hypothetical protein 0.0128 0.4056 0.429
Echinococcus granulosus tyrosine protein kinase Btk29A 0.009 0.2684 0.2839
Echinococcus multilocularis c src tyrosine kinase 0.0217 0.7292 0.7713
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Loa Loa (eye worm) RGC/RGC protein kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.0217 0.7292 0.7713
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Brugia malayi SH2 domain containing protein 0.0128 0.4056 0.429
Brugia malayi Muscleblind-like protein 0.0277 0.9455 1
Trypanosoma cruzi protein kinase, putative 0.009 0.2684 0.2684
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0083 0.2463 0.492
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trypanosoma cruzi metacaspase, putative 0.0026 0.0375 0.0375
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0375 0.0375
Echinococcus multilocularis calpain 5 0.0017 0.0062 0.0066
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0128 0.4085 0.8159
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0217 0.7292 0.7713
Loa Loa (eye worm) glutaminase 2 0.0264 0.8999 0.9518
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0041 0.0914 0.3404
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0375 0.002
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Schistosoma mansoni growth factor receptor-bound protein 0.0128 0.4056 0.4508
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0375 0.0417
Echinococcus granulosus tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Onchocerca volvulus 0.004 0.0898 0.0756
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Schistosoma mansoni flap endonuclease-1 0.0023 0.027 0.0301
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0033 0.0632 0.5
Echinococcus multilocularis ephrin type A receptor 4 A 0.009 0.2684 0.2839
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus tyrosine protein kinase Src42A 0.0217 0.7292 0.7713
Echinococcus granulosus caspase 2 0.0026 0.0375 0.0397
Schistosoma mansoni tyrosine kinase 0.0217 0.7292 0.8104
Brugia malayi ImpB/MucB/SamB family protein 0.0076 0.2192 0.2319
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Plasmodium falciparum glutathione reductase 0.0037 0.077 0.2868
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0217 0.7292 0.7713
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Echinococcus multilocularis tyrosine kinase 0.009 0.2684 0.2839
Echinococcus multilocularis protein kinase 0.009 0.2684 0.2839
Echinococcus granulosus protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis conserved hypothetical protein 0.009 0.2684 0.2692
Trypanosoma cruzi kinesin, putative 0.0017 0.0062 0.0062
Loa Loa (eye worm) TK/CSK protein kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Echinococcus granulosus ephrin type A receptor 4 A 0.009 0.2684 0.2839
Brugia malayi Probable tyrosine-protein kinase kin-31 0.009 0.2684 0.2839
Trypanosoma brucei unspecified product 0.0071 0.2001 0.2001
Echinococcus multilocularis SH2 domain containing protein 7 0.0128 0.4056 0.429
Echinococcus granulosus tyrosine kinase 0.0217 0.7292 0.7713
Schistosoma mansoni inositol monophosphatase 0.0033 0.0632 0.0702
Onchocerca volvulus 0.0128 0.4056 0.5322
Echinococcus granulosus protein tyrosine kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0375 0.0417
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0083 0.2463 0.492
Echinococcus multilocularis epidermal growth factor receptor 0.009 0.2684 0.2839
Echinococcus multilocularis caspase 8 0.0026 0.0375 0.0397
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0932 0.0932
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0128 0.4056 0.4508
Brugia malayi Variant SH3 domain containing protein 0.0128 0.4056 0.429
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0375 0.0397
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0033 0.0632 0.0678
Schistosoma mansoni suppressor of cytokine signaling 0.0128 0.4056 0.4508
Echinococcus granulosus inositol monophosphatase 1 0.0033 0.0632 0.0668
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Onchocerca volvulus Tyrosine kinase homolog 0.009 0.2684 0.3338
Loa Loa (eye worm) hypothetical protein 0.0024 0.0329 0.0348
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0217 0.7292 0.7713
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Echinococcus granulosus flap endonuclease 1 0.0025 0.0358 0.0378
Echinococcus granulosus tyrosine protein kinase HCK 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0017 0.0062 0.0062
Echinococcus multilocularis tyrosine protein kinase pr2 0.009 0.2684 0.2839
Loa Loa (eye worm) TK/KIN6 protein kinase 0.009 0.2684 0.2839
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0128 0.4056 0.429
Echinococcus multilocularis tyrosine kinase 0.0217 0.7292 0.7713
Echinococcus granulosus tensin 0.0128 0.4056 0.429
Brugia malayi hypothetical protein 0.0024 0.0329 0.0348
Mycobacterium ulcerans DNA polymerase IV 0.0077 0.2231 0.246
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.009 0.2684 0.2684
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Brugia malayi SH2 domain containing protein 0.0217 0.7292 0.7713
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0128 0.4056 0.429
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Trichomonas vaginalis conserved hypothetical protein 0.009 0.2684 0.2692
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0329 0.1225
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0023 0.0023
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.5006 1
Onchocerca volvulus 0.009 0.2684 0.3338
Plasmodium falciparum protein kinase, putative 0.009 0.2684 1
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Brugia malayi Sex muscle abnormal protein 5 0.0128 0.4056 0.429
Echinococcus multilocularis tyrosine protein kinase shark 0.0217 0.7292 0.7713
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0932 0.0932
Echinococcus granulosus tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Schistosoma mansoni tensin 0.0128 0.4056 0.4508
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Echinococcus granulosus integrin linked protein kinase 0.009 0.2684 0.2839
Brugia malayi hypothetical protein 0.009 0.2684 0.2839
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Echinococcus granulosus epidermal growth factor receptor 0.009 0.2684 0.2839
Echinococcus granulosus suppressor of cytokine signaling 7 0.0128 0.4056 0.429
Trypanosoma brucei DNA polymerase eta, putative 0.0076 0.2192 0.2192
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.2799 0.5592
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0953 0.0953
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0128 0.4056 0.429
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus tyrosine protein kinase Lyn 0.0217 0.7292 0.7713
Echinococcus multilocularis hypothetical protein 0.0017 0.0062 0.0066
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0375 0.0375
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Schistosoma mansoni caspase-3 (C14 family) 0.0026 0.0375 0.0417
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.009 0.2684 0.2839
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.009 0.2684 0.2983
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Loa Loa (eye worm) glutaminase 0.0264 0.8999 0.9518
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Schistosoma mansoni signal transduction protein lnk-related 0.0128 0.4056 0.4508
Loa Loa (eye worm) hypothetical protein 0.0146 0.4728 0.5
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0375 0.002
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Echinococcus granulosus tyrosine protein kinase Src42A 0.0128 0.4056 0.429
Echinococcus granulosus tyrosine kinase 0.0217 0.7292 0.7713
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0017 0.0062 0.0062
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.1256 0.1256
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.009 0.2684 0.2839
Trypanosoma brucei DNA polymerase IV, putative 0.0071 0.2001 0.2001
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Toxoplasma gondii protein kinase 0.009 0.2684 1
Entamoeba histolytica hypothetical protein 0.009 0.2688 0.3632
Echinococcus multilocularis tensin 0.0128 0.4056 0.429
Trypanosoma brucei beta lactamase 0.0062 0.1674 0.1674
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0217 0.7292 0.7713
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.009 0.2684 1
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Echinococcus granulosus geminin 0.0164 0.5368 0.5678
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0128 0.4056 0.4508
Brugia malayi Protein kinase domain containing protein 0.0217 0.7292 0.7713
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus tyrosine protein kinase Blk 0.0217 0.7292 0.7713
Schistosoma mansoni tyrosine kinase 0.0217 0.7292 0.8104
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.4442 0.4442
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Entamoeba histolytica serine/threonine kinase, putative 0.009 0.2684 0.3626
Echinococcus granulosus tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Echinococcus multilocularis kinase suppressor of Ras 1 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.0277 0.9455 1
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.009 0.2684 1
Echinococcus multilocularis activin receptor type 0.009 0.2684 0.2839
Schistosoma mansoni hypothetical protein 0.0128 0.4056 0.4508
Brugia malayi SRC-1 0.0217 0.7292 0.7713
Brugia malayi SH2 domain containing protein 0.0217 0.7292 0.7713
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0051 0.1302 0.1447
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0358 0.1333
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0128 0.4056 0.5322
Echinococcus granulosus calpain 7 C02 family 0.0017 0.0062 0.0066
Brugia malayi Cell death protein 3 precursor 0.0026 0.0375 0.0397
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0375 0.1398
Echinococcus granulosus signal transduction protein lnk realted 0.0128 0.4056 0.429
Toxoplasma gondii STE kinase 0.009 0.2684 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0932 0.0932
Entamoeba histolytica SH2 domain containing protein 0.0128 0.4056 0.5524
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.2231 0.2231
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0375 0.1398
Schistosoma mansoni serine/threonine RGC 0.009 0.2684 0.2983
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0083 0.2463 0.492
Onchocerca volvulus 0.009 0.2684 0.3338
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Echinococcus multilocularis tyrosine protein kinase Abl 0.0217 0.7292 0.7713
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0033 0.0632 0.0788
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.0057 0.1513 0.16
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Schistosoma mansoni tyrosine kinase 0.0217 0.7292 0.8104
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0051 0.1302 0.1377
Onchocerca volvulus 0.0217 0.7292 1
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.009 0.2684 0.2839
Brugia malayi glutaminase DH11.1 0.0264 0.8999 0.9518
Echinococcus multilocularis tyrosine protein kinase Blk 0.0217 0.7292 0.7713
Onchocerca volvulus 0.0128 0.4056 0.5322
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Loa Loa (eye worm) calpain family protein 1 0.0057 0.1513 0.16
Plasmodium vivax tyrosine kinase-like protein, putative 0.009 0.2684 1
Brugia malayi Thioredoxin reductase 0.0037 0.077 0.0814
Schistosoma mansoni calpain (C02 family) 0.0017 0.0062 0.0069
Giardia lamblia Kinase 0.009 0.2684 1
Brugia malayi SH2 domain containing protein 0.0128 0.4056 0.429
Echinococcus granulosus c src tyrosine kinase 0.0217 0.7292 0.7713
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Onchocerca volvulus 0.0217 0.7292 1
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0358 0.0409
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.009 0.2684 0.3338
Echinococcus multilocularis growth factor receptor bound protein 2 0.0128 0.4056 0.429
Brugia malayi Variant SH3 domain containing protein 0.0128 0.4056 0.429
Loa Loa (eye worm) calpain 0.0017 0.0062 0.0066
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.009 0.2684 0.2692
Plasmodium falciparum flap endonuclease 1 0.0025 0.0358 0.1333
Loa Loa (eye worm) TK/ACK protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Plasmodium falciparum tyrosine kinase-like protein 0.009 0.2684 1
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0128 0.4056 0.4508
Echinococcus multilocularis calpain A 0.006 0.1618 0.1712
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0128 0.4056 0.4508
Brugia malayi polk-prov protein 0.0042 0.0953 0.1007
Onchocerca volvulus 0.009 0.2684 0.3338
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0128 0.4056 0.429
Entamoeba histolytica protein kinase, putative 0.009 0.2684 0.3626
Leishmania major trypanothione reductase 0.0037 0.077 0.077
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Leishmania major hypothetical protein, conserved 0.0024 0.0329 0.0329
Entamoeba histolytica hypothetical protein 0.0035 0.0705 0.0889
Trichomonas vaginalis TK family protein kinase 0.009 0.2684 0.2692
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0217 0.7292 0.8104
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Brugia malayi integrin-linked kinase 0.009 0.2684 0.2839
Schistosoma mansoni tyrosine kinase 0.0217 0.7292 0.8104
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0375 0.002
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0705 0.0783
Onchocerca volvulus 0.009 0.2684 0.3338
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.009 0.2684 0.3626
Entamoeba histolytica tyrosine kinase, putative 0.009 0.2684 0.3626
Loa Loa (eye worm) hypothetical protein 0.0026 0.0375 0.0397
Trypanosoma cruzi metacaspase, putative 0.0026 0.0375 0.0375
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.009 0.2684 0.3626
Echinococcus multilocularis SH2 motif 0.0128 0.4056 0.429
Entamoeba histolytica hypothetical protein 0.0035 0.0705 0.0889
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.2684 0.2839
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0632 0.0632
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0375 0.1398
Loa Loa (eye worm) STAT protein 0.0128 0.4056 0.429
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Trypanosoma brucei DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Echinococcus multilocularis signal transduction protein lnk realted 0.0128 0.4056 0.429
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.009 0.2684 0.2839
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0375 0.002
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Loa Loa (eye worm) hypothetical protein 0.0128 0.4056 0.429
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0358 0.0378
Entamoeba histolytica hypothetical protein 0.0035 0.0705 0.0889
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0017 0.0062 0.0062
Schistosoma mansoni protein kinase 0.009 0.2684 0.2983
Brugia malayi Protein kinase domain containing protein 0.0217 0.7292 0.7713
Leishmania major protein kinase, putative 0.009 0.2684 0.2684
Entamoeba histolytica serine/threonine kinase, putative 0.009 0.2684 0.3626
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0329 0.0329
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Loa Loa (eye worm) RGC/RGC protein kinase 0.009 0.2684 0.2839
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0705 0.0746
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0128 0.4056 0.429
Trypanosoma brucei chrX additional, unordered contigs 0.0016 0.0023 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0023 0.0088
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis CAMK family protein kinase 0.009 0.2684 0.2692
Brugia malayi Furin-like cysteine rich region family protein 0.009 0.2684 0.2839
Loa Loa (eye worm) hypothetical protein 0.009 0.2684 0.2839
Brugia malayi Protein kinase domain containing protein 0.009 0.2684 0.2839
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0217 0.7292 0.7713
Loa Loa (eye worm) TK/FER protein kinase 0.0217 0.7292 0.7713
Schistosoma mansoni tyrosine kinase 0.009 0.2684 0.2983
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0128 0.4056 0.5322
Onchocerca volvulus 0.0217 0.7292 1
Echinococcus granulosus calpain A 0.006 0.1618 0.1712
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0217 0.7292 0.7713
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0017 0.0062 0.0062
Echinococcus granulosus dual specificity testis-specific protein kinase 0.009 0.2684 0.2839
Brugia malayi RhoGAP domain containing protein 0.0128 0.4056 0.429
Entamoeba histolytica protein kinase domain containing protein 0.009 0.2684 0.3626
Trypanosoma cruzi DNA polymerase kappa, putative 0.0077 0.2231 0.2231
Plasmodium falciparum DNA repair protein REV1, putative 0.0016 0.0023 0.0088
Mycobacterium tuberculosis Probable dehydrogenase 0.0083 0.2463 0.492
Entamoeba histolytica tyrosin kinase, putative 0.009 0.2684 0.3626
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0217 0.7292 0.7713
Loa Loa (eye worm) TK protein kinase 0.009 0.2684 0.2839
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Onchocerca volvulus 0.0146 0.4728 0.6292
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0023 0.0023
Echinococcus granulosus NCK adaptor protein 0.0128 0.4056 0.429
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.009 0.2684 0.2839
Schistosoma mansoni terminal deoxycytidyl transferase 0.0051 0.1302 0.1447
Trichomonas vaginalis TKL family protein kinase 0.009 0.2684 0.2692
Entamoeba histolytica hypothetical protein, conserved 0.009 0.2684 0.3626
Schistosoma mansoni tensin-related 0.0128 0.4056 0.4508
Schistosoma mansoni inositol monophosphatase 0.0033 0.0632 0.0702
Plasmodium falciparum protein kinase, putative 0.009 0.2684 1
Onchocerca volvulus 0.0128 0.4056 0.5322
Plasmodium vivax DNA repair protein REV1, putative 0.0016 0.0023 0.0088
Echinococcus granulosus caspase 0.0026 0.0375 0.0397
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0217 0.7292 0.7713
Giardia lamblia Kinase, NEK 0.009 0.2684 1
Loa Loa (eye worm) TK/FER protein kinase 0.009 0.2684 0.2839
Entamoeba histolytica hypothetical protein 0.009 0.2684 0.3626
Trypanosoma brucei kinesin, putative 0.0017 0.0062 0.0062
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.009 0.2684 0.2983
Echinococcus granulosus tyrosine protein kinase csk 0.009 0.2684 0.2839

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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